@article{HornRaptisFischeretal., author = {Horn, Lars-Christian and Raptis, Georgios and Fischer, Uta and Bilek, Karin}, title = {Impact of tumorload in surgically treated, histologically staged early cervical cancer: Multivariate analysis of 568 patients}, series = {International Journal of Gynecology \& Obstetrics}, volume = {70}, journal = {International Journal of Gynecology \& Obstetrics}, number = {Suppl. 1}, pages = {20 -- 21}, subject = {Geb{\"a}rmutterhalskrebs}, language = {en} } @article{HornRaptisFischeretal., author = {Horn, Lars-Christian and Raptis, Georgios and Fischer, Uta and Bilek, Karin}, title = {p53-tumorsuppressor gene in surgically treated histologically staged early cervical cancer}, series = {International Journal of Gynecology \& Obstetrics}, volume = {70}, journal = {International Journal of Gynecology \& Obstetrics}, number = {Suppl. 1}, pages = {112}, subject = {Tumorsuppressor-Gen}, language = {en} } @article{SchenkelAlbertRaptisetal., author = {Schenkel, Johannes and Albert, J{\"u}rgen and Raptis, Georgios and Butz, Norbert}, title = {Notfalldatensatz: Bessere Unterst{\"u}tzung f{\"u}r den Arzt}, series = {Deutsches {\"A}rzteblatt}, volume = {108}, journal = {Deutsches {\"A}rzteblatt}, number = {19}, pages = {A-1046, B-864, C-864}, subject = {Elektronische Gesundheitskarte}, language = {de} } @article{HornRaptisMartin, author = {Horn, Lars-Christian and Raptis, Georgios and Martin, Rosemarie}, title = {Tumorassoziierte Proteolyse, p53-Immunhistochemie und Zelladh{\"a}sion bei prim{\"a}r operierten Zervixkarzinomen}, series = {Geburtshilfe und Frauenheilkunde}, volume = {60}, journal = {Geburtshilfe und Frauenheilkunde}, number = {Suppl. 1}, pages = {200}, subject = {Tumorassoziierte Proteolyse}, language = {de} } @article{SchenkelAlbertRaptisetal., author = {Schenkel, Johannes and Albert, J{\"u}rgen and Raptis, Georgios and Butz, Norbert}, title = {Notfalldatenmanagement auf der elektronischen Gesundheitskarte}, series = {e-Health}, journal = {e-Health}, editor = {Duesberg, Felix}, publisher = {medical future verlag}, address = {Solingen}, pages = {64 -- 67}, subject = {Elektronische Gesundheitskarte}, language = {de} } @inproceedings{Raptis, author = {Raptis, Georgios}, title = {Notfalldaten und Datenerhalt mit der elektronischen Gesundheitskarte.}, series = {Tagungsband 22. Smartcard-Workshop 2012}, booktitle = {Tagungsband 22. Smartcard-Workshop 2012}, publisher = {Fraunhofer-Verlag}, pages = {166}, subject = {Elektronische Gesundheitskarte}, language = {de} } @misc{Raptis, author = {Raptis, Georgios}, title = {Biometrie - Anwendungen und Datenschutz. Welche Zusatzinformationen liefert der IRIS-Pf{\"o}rtner? Nebennutzen in einem biometrischen Zugangskontrollsystem. Medizinische Hintergr{\"u}nde. Symposium des Bundesamtes f{\"u}r Sicherheit in der Informationstechnik, Vortrag, Darmstadt 23. Mai 2002}, series = {Symposium des Bundesamtes f{\"u}r Sicherheit in der Informationstechnik}, journal = {Symposium des Bundesamtes f{\"u}r Sicherheit in der Informationstechnik}, language = {de} } @article{LekakisNanasPrassopoulosetal., author = {Lekakis, J. and Nanas, J. and Prassopoulos, V. and Raptis, Georgios}, title = {Cardiac I-123 metaiodobenzylguanidine uptake in predicting early and late mortality in patients with congestive heart failure}, series = {Circulation (Suppl.)}, volume = {96}, journal = {Circulation (Suppl.)}, number = {8}, pages = {2104}, subject = {Stauungssuffizienz}, language = {en} } @article{HornFischerTannapfeletal., author = {Horn, Lars-Christian and Fischer, Uta and Tannapfel, A. and Kuhn, H. and H{\"a}nel, C. and Raptis, Georgios}, title = {The role of p53 tumorsuppressorgene in tumor progression in cervical cancer}, series = {Pathology - Research and Practice}, volume = {195}, journal = {Pathology - Research and Practice}, pages = {328}, subject = {Tumorsuppressor-Gen}, language = {en} } @techreport{SchenkelAlbertRaptis, type = {Working Paper}, author = {Schenkel, Johannes and Albert, J{\"u}rgen and Raptis, Georgios}, title = {Arbeitskonzept Notfalldatenmanagement}, subject = {Elektronische Gesundheitskarte}, language = {de} } @phdthesis{Raptis, author = {Raptis, Georgios}, title = {Vertraulichkeit von medizinischen Daten in der Telematik-Infrastruktur - Sicherheitsanalyse unter Ber{\"u}cksichtigung von Aspekten der langfristigen Sicherheit}, address = {Heidelberg}, subject = {Medizinische Dokumentation}, language = {de} } @misc{Raptis, author = {Raptis, Georgios}, title = {Mechanismen und Einsatzkonzepte von Heilberufsausweis und elektronischer Gesundheitskarte}, series = {Oberseminar im Fachbereich Informatik, Kryptographie und Computeralgebra der TU-Darmstadt, 28.11.2006}, journal = {Oberseminar im Fachbereich Informatik, Kryptographie und Computeralgebra der TU-Darmstadt, 28.11.2006}, subject = {Elektronische Gesundheitskarte}, language = {de} } @article{HoehGamaelRaptis, author = {H{\"o}h, H. and Gamael, A. and Raptis, Georgios}, title = {Energie und Phakozeit bei Ultraschall und Laserphakoemulsifikation}, series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, volume = {217}, journal = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, number = {Suppl. 8}, pages = {5}, subject = {Phakoemulsifikation}, language = {de} } @misc{Raptis, author = {Raptis, Georgios}, title = {Einsatzm{\"o}glichkeiten des elektronischen Heilberufsausweises}, series = {CAST-Forums, Fraunhofer IGD, 14.09.2006}, journal = {CAST-Forums, Fraunhofer IGD, 14.09.2006}, subject = {Heilberuf}, language = {de} } @article{HornbergerMarquisChristiansenetal., author = {Hornberger, Helga and Marquis, Peter M. and Christiansen, Silke H. and Strunk, Horst P.}, title = {Microstructure of a high strength alumina glass composite}, series = {Journal of Materials Research}, volume = {11}, journal = {Journal of Materials Research}, number = {4}, doi = {10.1557/JMR.1996.0104}, pages = {855 -- 858}, abstract = {The morphology and microstructure of an Al2O3 glass composite (trade name In-Ceram, Vita Zahnfabrik) were studied using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The composite was produced by infiltration of a lanthanum-based glass throughout a porous Al2O3 body. This alumina body was formed by three classes of particles differing in size and shape: faceted particles typically ≤4 μm in diameter, platelets of average diameter 8 μm, 1.5 μm thickness, and small spheres 0.4 μm in diameter. The outstanding strength properties of the composite (600 MPa, ball-on-ring test) are a result of the high wetting capability of the glass phase on the Al2O3 surface. In addition, plastic strain relaxation in the faceted particles by dislocation formation compensates partially for residual stresses and impedes crack formation at the glass/Al2O3 interface.}, language = {en} } @misc{HornbergerThielVollmann, author = {Hornberger, Helga and Thiel, Norbert and Vollmann, Markus}, title = {Fully ceramic tooth replacement with a frame made of cer-stabilised zircon-oxide}, pages = {8}, abstract = {Vollkeramischer Zahnersatz mit einem Ger{\"u}st, das aus einem Ger{\"u}stmaterial aus einem Cer-stabilisierten Zirkonoxid (Ce-ZrO2) mit einem Anteil von bis zu 25 Gew\% Aluminiumoxid (Al2O3) bezogen auf den Anteil an ZrO2 aufgebaut ist und einem Infiltrationsglasanteil im Ger{\"u}st von 0-40 Vol\% bezogen auf das Volumen des Ger{\"u}sts sowie einer auf das Ger{\"u}stmaterial abgestimmten Verblendkeramik.Die Erfindung betrifft die Verwendung von cer-stabilisiertem ZrO2 zur Herstellung von Ger{\"u}stmaterialien, die als Restauration im Dentalbereich einsetzbar sind.}, language = {en} } @article{GebhardtSeussTurhanetal., author = {Gebhardt, F. and Seuss, Sigrid and Turhan, Metehan C. and Hornberger, Helga and Virtanen, Sannakaisa and Boccaccini, Aldo R.}, title = {Characterization of electrophoretic chitosan coatings on stainless steel}, series = {Materials Letters}, volume = {66}, journal = {Materials Letters}, number = {1}, doi = {10.1016/j.matlet.2011.08.088}, pages = {302 -- 304}, abstract = {Electrophoretic chitosan deposits on stainless steel AISI 316 L were produced and characterized. The coating quality (thickness, defectiveness, corrosion protection ability) was seen to depend on the electric field used for EPD. Corrosion studies in concentrated simulated body fluid (SBF5) demonstrated that the surface characteristics of AISI 316 L can be positively influenced by the chitosan coating.}, language = {en} } @misc{AechtnerHornbergerNageletal., author = {Aechtner, Stefan and Hornberger, Helga and Nagel, Emil and Thiel, Norbert}, title = {Composite material and method for the preparation thereof}, pages = {5}, abstract = {A composite material with a porous inorganic-nonmetallic matrix and a second material, characterized in that said porous inorganic-nonmetallic matrix has a bending strength of >=40 MPa as measured according to ISO 6 872; said second material is an organic material which at least partly fills the pores of said porous matrix; and said composite material has a modulus of elasticity, E, of >=25 GPa as measured according to ISO 10 477.}, language = {en} } @misc{MuerrleHornberger, author = {Muerrle, Ulrich and Hornberger, Helga}, title = {Method of making a ceramic restoration}, pages = {8}, abstract = {Production of a dental reconstruction comprises: (a) forming a mold (12) from a model (10); (b) using (12) to make an isotropically heat-expandable replica from a ceramic precursor (14); (c) oxidizing (14) to produce an enlarged ceramic replica; (d) forming a silicone mold from this replica; (e) using (d) to make a second ceramic replica; and (f) sintering the second replica with volume reduction to form a replica identical to (10).}, language = {en} } @article{HornbergerMarquisFranks, author = {Hornberger, Helga and Marquis, Peter M. and Franks, J.}, title = {The impact of diamond-like coatings on the strength of dental ceramics}, series = {Journal of Dental Research}, volume = {74}, journal = {Journal of Dental Research}, pages = {522}, language = {en} } @article{HornbergerMarquis, author = {Hornberger, Helga and Marquis, Peter M.}, title = {Mechanical properties and microstructure of In-Ceram}, series = {Glastechnische Berichte - Glass Science and Technology}, volume = {68}, journal = {Glastechnische Berichte - Glass Science and Technology}, number = {6}, pages = {188 -- 194}, language = {en} } @article{ManarancheHornberger, author = {Manaranche, Claire and Hornberger, Helga}, title = {A proposal for the classification of precious dental alloys according to their resistance to corrosion based on the iso 10271 standard}, series = {European Cells and Materials}, volume = {5}, journal = {European Cells and Materials}, number = {SUPPL. 1}, publisher = {Univ. of Wales}, address = {Aberystwyth, Wales}, pages = {34 -- 36}, abstract = {A lot of dental alloys are available on the market. Among these alloys, there are the conventional alloys, the so called casting alloys used without ceramics, the bonding alloys used with high fusing ceramics and the universal alloys used without or with low fusing ceramics. It is im portant to know the physical and mechanical properties of these materials but also their biocompatibility and their resistance to corrosion. Dental alloys are generally placed in the mouth for many years, they must not induce adverse biological reactions such as gingival swelling and erythema, mucosal pain and lichenoid reactions. Although these troubles are often caused not by the materials itself (1, 2), they can be induced by the metallic ions released during their corrosion. In order to decrease the risks to the health, it is necessary to study the corrosion of the dental alloys. Currently, the ISO 10271 Standard (3), describes 3 different corrosion tests: a static immersion test (chemical corrosion), an electrochemic al test and a tarnish test. However, there are no indications yet about the possible interpretation of test results. In this paper, we propose a method to compare and classify the dental alloys in relation to their chemical and electrochemical corrosion results. METHODS: The material tested are pure metals such as gold, palladium, silver, copper and zinc as well as dental alloys which are commercially sold (see Table 1). 54 different materials have been tested. A minimum of four samples of each material were tested by electrochemic al corrosio n and a minimum of three in chemical test. The samples were cast and prepared as indicated by the manufacturer and by the ISO 10271. For the electrochemical test, the samples are in the form of disks 11 mm in diameter. They are tested with a potentiostat/galvanostat Voltalab Model 21. For the chemical test, the samples are rectangular with the dimensions 35X10X1.7 mm. The solution used and the operating conditions are described in the ISO 10271. The concentration of metallic ions released is measured by Induced Coupled Plasma}, language = {en} } @article{HornbergerWeissmannLutz, author = {Hornberger, Helga and Weissmann, R. and Lutz, N.}, title = {Machining of silica glasses using excimer laser radiation}, series = {Glastechnische Berichte - Glass Science and Technology}, volume = {69}, journal = {Glastechnische Berichte - Glass Science and Technology}, number = {2}, pages = {44 -- 49}, language = {en} } @article{WesselyHausleiterMichaelisetal., author = {Wessely, Rainer and Hausleiter, J{\"o}rg and Michaelis, Cornelia and Jaschke, Birgit and Vogeser, Michael and Milz, Stefan and Behnisch, Boris and Schratzenstaller, Thomas and Renke-Gluszko, Magdalena and St{\"o}ver, Michael and Wintermantel, Erich and Kastrati, Adnan and Sch{\"o}mig, Albert}, title = {Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating}, series = {Arteriosclerosis, Thrombosis, and Vascular Biology}, volume = {25}, journal = {Arteriosclerosis, Thrombosis, and Vascular Biology}, number = {4}, issn = {1524-4636}, doi = {10.1161/01.ATV.0000157579.52566.ee}, pages = {748 -- 753}, abstract = {Objective The risk of in-stent restenosis can be considerably reduced by stents eluting cytostatic compounds. We created a novel drug-eluting stent system that includes several new features in the rapidly evolving field of stent-based drug delivery. Methods and Results The aim of the present study was the preclinical evaluation of a stent-coating system permitting individual, on-site coating of stents with a unique microporous surface allowing for individualizable, dose-adjustable, and multiple coatings with identical or various compounds, designated ISAR (individualizable drug-eluting stent system to abrogate restenosis). Stents were coated with 0.75\% rapamycin solution, and high-performance liquid chromatography (HPLC)-based determination of drug release profile indicated drug release for >21 days. Rapamycin-eluting microporous (REMP) stents implanted in porcine coronary arteries were safe. To determine the efficacy of REMP stents, this novel drug-eluting stent platform was compared with the standard sirolimus-eluting stent. At 30 days, in-stent neointima formation in porcine coronary arteries was similar in both groups, yielding a significant decrease of neointimal area and injury-dependent neointimal thickness compared with bare-metal stents. Conclusion The ISAR drug-eluting stent platform as a novel concept for stent coating allows for a safe, effective, on-site stent coating process, thus justifying further clinical evaluation to decrease in-stent restenosis in humans. In-stent neointima formation can be successfully attenuated by drug-eluting stents. We introduce a novel conceptual approach for stent-coating that allows for dose-adjustable, on-site stent coating process if desired with multiple compounds. Microporous stents coated with rapamycin proved safe and effective for the limitation of neointima formation in a porcine coronary stent model.}, language = {en} } @article{HausleiterKastratiWesselyetal., author = {Hausleiter, J{\"o}rg and Kastrati, Adnan and Wessely, Rainer and Dibra, Alban and Mehilli, Julinda and Schratzenstaller, Thomas and Graf, Isolde and Renke-Gluszko, Magdalena and Behnisch, Boris and Dirschinger, Josef and Wintermantel, Erich and Sch{\"o}mig, Albert}, title = {Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating}, series = {European Heart Journal - Clinical research}, volume = {26}, journal = {European Heart Journal - Clinical research}, number = {15}, doi = {10.1093/eurheartj/ehi405}, pages = {1475 -- 1481}, abstract = {Aims Drug-eluting stents (DES) represent a major advance in interventional cardiology. Along with the success shown, current DES also present limitations related to the presence of polymer-coating, fixed drug, and dose used. With the ISAR (Individualized Drug-Eluting Stent System to Abrogate Restenosis) project, a DES system has been developed that permits individualized choice of the drug and dose to use for the given patient. The objective of this prospective dose finding study was to assess the feasibility, safety, and efficacy of a polymer-free on-site stent coating with increasing rapamycin doses. Methods and results In this dose finding study, 602 patients were sequentially enrolled in four groups: microporous bare metal stent (BMS), DES stents coated with a 0.5, 1.0, and 2.0\% rapamycin solution. The angiographic in-segment restenosis rate at follow-up angiography was the primary study endpoint. In-segment restenosis was significantly reduced from 25.9\% with BMS to 18.9, 17.2, and 14.7\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.024). Similarly, the need for target lesion revascularization at 1 year follow-up was reduced from 21.5\% with BMS to 16.4, 12.6, and 8.8\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.006). Conclusion The placement of polymer-free stents coated on-site with rapamycin is feasible and safe. Furthermore, a dose-dependent efficacy in restenosis prevention is achievable with this new DES concept.}, language = {en} } @incollection{Weber, author = {Weber, Karsten}, title = {Der Preis der Informationsfreiheit}, series = {Wissen und Bildung in der modernen Gesellschaft}, booktitle = {Wissen und Bildung in der modernen Gesellschaft}, publisher = {Rosa-Luxemburg-Stiftung e.V.}, address = {Leipzig}, language = {de} }