@incollection{BlahnikovaMuellerWaasetal., author = {Blahn{\´i}kov{\´a}, Barbora and M{\"u}ller, D. and Waas, M. and Lechner, Alfred}, title = {Multilyzer - Mikrofluidisches Echtzeitmesssystem f{\"u}r die Analyse umweltrelevanter Substanzen}, series = {7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, M{\"u}nchen}, booktitle = {7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, M{\"u}nchen}, publisher = {VDE-Verlag}, address = {M{\"u}nchen}, isbn = {978-3-8007-4491-6}, pages = {382 -- 385}, abstract = {Die {\"u}berm{\"a}ßige Verwendung von stickstoffbasierten D{\"u}ngemitteln in der Landwirtschaft stellt eine Gef{\"a}hrdung f{\"u}r die Umwelt und Lebewesen dar. So ist die Analyse von Boden- und Grundwasser zu einem wesentlichen Bestandteil der Nachhaltigkeit und der {\"o}kologischen Erhaltung geworden. Daf{\"u}r bietet der Multilyzer eine passende L{\"o}sung. Der Multilyzer ist ein mikrofluidisches Analysesystem zur Bestimmung niedrigster Konzentrationen von Nitrat, Nitrit und Ammonium, die alle wesentliche Bestandteile des Stickstoffkreislaufs sind. Welche bei {\"U}berm{\"a}ßiger Aufnahme im K{\"o}rper krebserregend wirken und den Sauerstofftransport im Blutkreislauf st{\"o}ren. Der Aufbau ist eine Kombination aus Absorptions- und Fluoreszenzspektroskopie. Der Betrieb mit einer 12 Volt Batterie erm{\"o}glicht die Verwendung des Multilyzer-Systems zur Online-Messung im Feld. Somit k{\"o}nnen sehr kurze Analysezeiten realisiert und der Einfluss von Umwandlungs- bzw. Abbauprozessen vermieden werden. Das gesamte Messsystem wird im Kompetenzzentrum Nanochem an der OTH Regensburg entwickelt, inklusive Fertigungstechnologien, Software- und Hardwaresteuerung.}, language = {de} } @inproceedings{BiekerRoustaieLangeretal., author = {Bieker, Johannes and Roustaie, Farough and Langer, Christoph and Schreiner, Rupert and Schlaak, Helmut F.}, title = {Innovatives Verfahren zur Herstellung und Integration metallischer Nanokonen f{\"u}r die Feldemission}, series = {MikroSystemTechnik Kongress 2017 : MEMS, Mikroelektronik, Systeme 23.-25. Oktober 2017 in M{\"u}nchen}, booktitle = {MikroSystemTechnik Kongress 2017 : MEMS, Mikroelektronik, Systeme 23.-25. Oktober 2017 in M{\"u}nchen}, number = {CD-ROM}, publisher = {VDE-Verlag}, address = {M{\"u}nchen}, isbn = {978-3-8007-4491-6}, pages = {797 -- 800}, abstract = {In den letzten Jahren wurde am Institut f{\"u}r Elektromechanische Konstruktionen die Fabrikation und Integration von metallischen Nanodr{\"a}hten und Nanokonen mittels Template-basierter Abscheidung erforscht. Diese Variante der in-situ Abscheidung von metallischen Nanostrukturen bietet eine Vielzahl von Anwendungsm{\"o}glichkeiten. Im Rahmen dieses Beitrags werden das Herstellungsverfahren zur Herstellung metallischer Nanokonen vorgestellt. Dies beinhaltet sowohl die Templatepr{\"a}paration mittels asymmetrischen {\"A}tzens als auch die anschließende Integration mittels galvanischer Abscheidung. Eine Anwendung der metallischen Nanokonen stellt die Verwendung als Feldemitter in der Vakuumelektronik dar. Es werden erste Messungen der Langzeitstabilit{\"a}t des Feldemissionsstromes der metallischen Konen pr{\"a}sentiert.}, language = {de} } @incollection{BetzLechner, author = {Betz, Michael A. and Lechner, Alfred}, title = {Sprayganik - Spraytool f{\"u}r organische Halbleiter}, series = {7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, M{\"u}nchen}, booktitle = {7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, M{\"u}nchen}, publisher = {VDE-Verlag}, address = {M{\"u}nchen}, isbn = {978-3-8007-4491-6}, pages = {747 -- 750}, abstract = {Spr{\"u}hbeschichtung stellt einen kosteng{\"u}nstigen und materialeffizienten aber komplexen Prozess dar. Um diese Vorteile f{\"u}r die Abscheidung teurer organischer Halbleiter zu nutzen, wurde ein Spr{\"u}hbeschichter entwickelt, der neueste Anforderungen an den Prozess erf{\"u}llt. Zudem konnten selbstansaugende Mikrospr{\"u}hd{\"u}sen mikrotechnologisch in Silizium realisiert werden, welche bereits eine bis zu vierfache Materialeffizienz im Vergleich zu herk{\"o}mmlichen airbrush-D{\"u}sen nachweisen konnten. Die neueste D{\"u}sengeneration zeigt nun eine weiter verbesserte Zerst{\"a}ubung, was bei gespr{\"u}hten OPDs zu einer reduzierten Dunkelstromdichte von 9,1×10-6 mA·cm-2 (-5 V) und erh{\"o}hten externen Quanteneffizienz von 78,5\% (530 nm, -5 V) f{\"u}hrt.}, language = {de} } @unpublished{AmatHalimahIshaketal., author = {Amat, A. and Halimah, M. K. and Ishak, M. and Nazrin, S. N. and Syamimi, Nik Nur and Hasnimulyati, L.}, title = {Electronic Polarizability and Optical Basicity of BaO-B2O3-TeO2 Glass System}, edition = {Version 1, posted 30 Nov, 2021}, doi = {10.21203/rs.3.rs-1093838/v1}, abstract = {[(TeO2)0.7(B2O3)0.3]1-x (BaO)x, x = 0.00, 0.05, 0.10, 0.20, 0.25, 0.30 and 0.35 mol fraction glass series were successfully synthesized by conventional melt quenching method. Amorphous phase of all samples was confirmed through X-ray diffraction while optical properties were determined using UV-VIS spectrophotometer. Fourier Transform Infrared (FTIR) analysis showed that the glass structure consisted of TeO3, TeO4, TeO6, BO3 and BO4 structural units. The optical band gap energy, Eopt which was calculated from Tauc' plots decreased as the amount of BaO increases, whereas, the Urbach energy value increased. The increase in Urbach energy value was attributed to the increase of defects in glass structure. The refractive indices of glass were found to increase along with the increased amount of BaO, due to the high polarization and high density of host material and glass modifier. The molar polarizability, αm, oxide ion polarizability, αo2- and optical basicity, Λ of the glasses are calculated by Lorentz-Lorenz equation. The glasses were found to possess αm values between 8.106 - 8.489 {\AA}3, and αo2- values between 3.303 to 4.772. Meanwhile, optical basicity increases from 0.115 to 0.893.

}, language = {en} } @inproceedings{RahimanBerndtSchreiner, author = {Rahiman, Mohd Fuad and Berndt, Dominik and Schreiner, Rupert}, title = {Micro-wire Pirani with temperature-stabilized Environment}, series = {3. Symposium Elektronik und Systemintegration ESI 2022: 06. April 2022, Hochschule Landshut}, booktitle = {3. Symposium Elektronik und Systemintegration ESI 2022: 06. April 2022, Hochschule Landshut}, isbn = {978-3-9818439-7-2}, pages = {52 -- 59}, language = {en} } @misc{Schreiner, author = {Schreiner, Rupert}, title = {Miniaturized sensor and actuator elements based on the heat transport in gases or the ionization of gas particles}, series = {16th International Conference on Optical and Electronic Sensors, COE'2020, 29 March - 2 April 2020, Krakow, Poland (online)}, journal = {16th International Conference on Optical and Electronic Sensors, COE'2020, 29 March - 2 April 2020, Krakow, Poland (online)}, language = {en} } @book{OPUS4-3319, title = {Philosophie und Phantastik}, editor = {Weber, Karsten and Friesen, Hans and Zoglauer, Thomas}, publisher = {Mentis}, address = {M{\"u}nster}, isbn = {978-3-95743-073-1}, language = {de} } @inproceedings{KleshchSerbunOrekhovetal., author = {Kleshch, Victor I. and Serbun, Pavel and Orekhov, Anton and L{\"u}tzenkirchen-Hecht, Dirk and Obraztsov, Alexander N. and Prommesberger, Christian and Langer, Christoph and Schreiner, Rupert and Lutzenkirchen-Hecht, Dirk}, title = {Field emission properties of p-type silicon tips decorated with tungsten nanoparticles}, series = {2017 30th International Vacuum Nanoelectronics Conference (IVNC), 10-14 July 2017, Regensburg, Germany}, booktitle = {2017 30th International Vacuum Nanoelectronics Conference (IVNC), 10-14 July 2017, Regensburg, Germany}, publisher = {IEEE}, doi = {10.1109/IVNC.2017.8051580}, pages = {138 -- 139}, abstract = {An array of conical-shaped p-type silicon tips was fabricated by using reactive ion etching and sharpening oxidation. The apex of each tip was decorated by a tungsten hemispherical nanoparticle. Field emission properties of the tips were measured by a tungsten-needle anode positioned above the tip apex. Tips decorated with tungsten nanoparticles demonstrated a smaller saturation region in current-voltage characteristics compared to the pristine tips. An emission activation process, which consisted in sudden current increase at certain value of applied voltage, was observed for the decorated silicon tips. This behavior was explained by the formation of vertical protrusions extending from the metal particles revealed by scanning electron microscopy after field emission experiments.}, language = {en} } @inproceedings{WickLindnerZimmeretal., author = {Wick, Michael and Lindner, Gerhard and Zimmer, Katja and Schreiner, Rupert and Fuhrmann, Thomas and Seebauer, Gudrun and Xu, Boqing and Zheng, Jihong and Wang, Ning}, title = {German-Chinese cooperative Bachelor in engineering physics/optoelectronics}, series = {14th Conference on Education and Training in Optics and Photonics: ETOP 2017; Hangzhou, China 29.05.2017 - 31.05.2017}, booktitle = {14th Conference on Education and Training in Optics and Photonics: ETOP 2017; Hangzhou, China 29.05.2017 - 31.05.2017}, editor = {Liu, Xu and Zhang, Xi-Cheng}, publisher = {SPIE}, isbn = {9781510613812}, doi = {10.1117/12.2269943}, abstract = {The University of Shanghai for Science and Technology (USST), the Coburg University of Applied Sciences and Arts (CUASA) and the OTH Regensburg, University of Applied Sciences (OTHR) established an English taught international cooperative bachelor program in the area of Engineering Physics/Optoelectronics. Students from China study their first four semesters at USST. They continue their studies in Germany for the last three semesters, including an internship and a bachelor thesis, graduating with a Chinese and a German bachelor degree. Students from Germany study their third and fourth semester at USST to gain international experience. While the first cohort of Chinese students is currently in Germany, the second cohort of German students is in Shanghai. Up to now the feedback regarding this study program is completely positive, thus it is planned to develop it further.}, language = {en} } @inproceedings{KnappLangerPrommesbergeretal., author = {Knapp, Wolfram and Langer, Christoph and Prommesberger, Christian and Lindner, Matthias and Schreiner, Rupert}, title = {Investigations of the transition from field electron emission to stable plasma discharge in a micro electron source at vacuum pressure}, series = {2017 30th International Vacuum Nanoelectronics Conference (IVNC), 10-14 July 2017, Regensburg, Germany}, booktitle = {2017 30th International Vacuum Nanoelectronics Conference (IVNC), 10-14 July 2017, Regensburg, Germany}, publisher = {IEEE}, doi = {10.1109/IVNC.2017.8051594}, pages = {166 -- 167}, abstract = {We report on the transition from field electron emission to plasma discharges. During an experiment with a miniaturized field emission electron source a plasma discharge accompanied by a luminous effect was observed. A novel graphical evaluation method was used to interpret and to compare the observed phenomenon.}, language = {en} } @misc{HartmannSattler, author = {Hartmann, Julia and Sattler, Florian}, title = {Knowledge Nuggets in der Lehre}, language = {de} } @article{WunderlichHauslerMaerkletal., author = {Wunderlich, Lukas and Hausler, Peter and Maerkl, Susanne and Bierl, Rudolf and Hirsch, Thomas}, title = {Nanoparticle Determination in Water by LED-Excited Surface Plasmon Resonance Imaging}, series = {Chemosensors}, volume = {9}, journal = {Chemosensors}, number = {7}, publisher = {MDPI}, issn = {2227-9040}, doi = {10.3390/chemosensors9070175}, pages = {1 -- 9}, abstract = {The increasing popularity of nanoparticles in many applications has led to the fact that these persistent materials pollute our environment and threaten our health. An online sensor system for monitoring the presence of nanoparticles in fresh water would be highly desired. We propose a label-free sensor based on SPR imaging. The sensitivity was enhanced by a factor of about 100 by improving the detector by using a high-resolution camera. This revealed that the light source also needed to be improved by using LED excitation instead of a laser light source. As a receptor, different self-assembled monolayers have been screened. It can be seen that the nanoparticle receptor interaction is of a complex nature. The best system when taking sensitivity as well as reversibility into account is given by a dodecanethiol monolayer on the gold sensor surface. Lanthanide-doped nanoparticles, 29 nm in diameter and with a similar refractive index to the most common silica nanoparticles were detected in water down to 1.5 mu g mL(-1). The sensor can be fully regenerated within one hour without the need for any washing buffer. This sensing concept is expected to be easily adapted for the detection of nanoparticles of different size, shape, and composition, and upon miniaturization, suitable for long-term applications to monitor the quality of water.}, language = {en} } @article{SchreinerSchweizer, author = {Schreiner, Rupert and Schweizer, Heinz C.}, title = {High-frequency operation of 1.57-μm laterally coupled distributed feedback lasers with self-aligned ohmic contacts and nickel surface gratings}, series = {IEEE Journal of Selected Topics in Quantum Electronics}, volume = {9}, journal = {IEEE Journal of Selected Topics in Quantum Electronics}, number = {5}, publisher = {IEEE}, doi = {10.1109/JSTQE.2003.819469}, pages = {1179 -- 1182}, abstract = {Laterally coupled distributed feedback lasers with self-aligned ohmic contacts show the advantage of a considerably simplified fabrication process. These lasers exhibit superior spectral properties with full benefit from the gain coupling mechanism. Side-mode suppression ratios up to 55- and 3-dB bandwidths beyond 15 GHz were obtained for these devices.}, language = {en} } @article{BenderFahriogluYamaciTaneri, author = {Bender, Guzide and Fahrioglu Yamaci, Rezan and Taneri, Bahar}, title = {CRISPR and KRAS: a match yet to be made}, series = {Journal of biomedical science}, volume = {28}, journal = {Journal of biomedical science}, publisher = {Springer Nature}, doi = {10.1186/s12929-021-00772-0}, pages = {1 -- 25}, abstract = {CRISPR (clustered regularly interspaced short palindromic repeats) systems are one of the most fascinating tools of the current era in molecular biotechnology. With the ease that they provide in genome editing, CRISPR systems generate broad opportunities for targeting mutations. Specifically in recent years, disease-causing mutations targeted by the CRISPR systems have been of main research interest; particularly for those diseases where there is no current cure, including cancer. KRAS mutations remain untargetable in cancer. Mutations in this oncogene are main drivers in common cancers, including lung, colorectal and pancreatic cancers, which are severe causes of public health burden and mortality worldwide, with no cure at hand. CRISPR systems provide an opportunity for targeting cancer causing mutations. In this review, we highlight the work published on CRISPR applications targeting KRAS mutations directly, as well as CRISPR applications targeting mutations in KRAS-related molecules. In specific, we focus on lung, colorectal and pancreatic cancers. To date, the limited literature on CRISPR applications targeting KRAS, reflect promising results. Namely, direct targeting of mutant KRAS variants using various CRISPR systems resulted in significant decrease in cell viability and proliferation in vitro, as well as tumor growth inhibition in vivo. In addition, the effect of mutant KRAS knockdown, via CRISPR, has been observed to exert regulatory effects on the downstream molecules including PI3K, ERK, Akt, Stat3, and c-myc. Molecules in the KRAS pathway have been subjected to CRISPR applications more often than KRAS itself. The aim of using CRISPR systems in these studies was mainly to analyze the therapeutic potential of possible downstream and upstream effectors of KRAS, as well as to discover further potential molecules. Although there have been molecules identified to have such potential in treatment of KRAS-driven cancers, a substantial amount of effort is still needed to establish treatment strategies based on these discoveries. We conclude that, at this point in time, despite being such a powerful directed genome editing tool, CRISPR remains to be underutilized for targeting KRAS mutations in cancer. Efforts channelled in this direction, might pave the way in solving the long-standing challenge of targeting the KRAS mutations in cancers.}, language = {en} } @inproceedings{HauslerRothVitzthumeckeretal., author = {Hausler, Peter and Roth, Carina and Vitzthumecker, Thomas and Bierl, Rudolf}, title = {Miniaturized Surface Plasmon Resonance Based Sensor Systems}, series = {Optics, Photonics and Laser Technology 2018}, booktitle = {Optics, Photonics and Laser Technology 2018}, editor = {Ribeiro, Paulo and Raposo, Maria}, publisher = {Springer Nature}, address = {Cham}, isbn = {978-3-030-30112-5}, doi = {10.1007/978-3-030-30113-2_8}, pages = {169 -- 195}, abstract = {Surface Plasmon Resonance (SPR) is a well-known and established technology in bioanalysis and pharmaceutical sciences. Due to the expensive instrumentation and the need of trained people, it is mainly limited to applications in laboratories. However, there are some areas like environmental monitoring, chemical processing and civil infrastructure, which urgently need new sensor technologies. SPR has the potential to serve these fields. In order to be qualified for a use in these areas SPR has to overcome some hurdles. The instrumentation has to be robust, small in size and cheap. A device, which fits these needs, will be a micro-opto-electro-mechanical system (MOEMS) with integrated intelligent algorithms. In this book chapter, examples of miniaturized SPR devices are introduced, the limitations which have to be overcome as well as the possibilities for future applications are proposed. Due to the manifold advantages of this technology and the dropping prices for imaging sensors, Surface Plasmon Resonance imaging (SPRi) might become one of the leading technologies for SPR smart sensor systems.}, language = {en} } @incollection{SingladePonte, author = {Singla, Rashmi and de Ponte, Ulrike}, title = {Love in the Context of Transnational Academic Exchanges: Promoting Mental Health and Wellbeing}, series = {International Handbook of Love}, volume = {67}, booktitle = {International Handbook of Love}, editor = {Mayer, Claude-H{\´e}l{\`e}ne and Vanderheiden, Elisabeth}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-030-45995-6}, doi = {10.1007/978-3-030-45996-3_32}, pages = {599 -- 620}, abstract = {Educational and cultural dimensions of transnational academic exchange such as student exchanges, double degree programmes, internships have been researched but the romantic dimensions are almost overlooked, especially qualitatively, while Green (EU's Erasmus study abroad programme is 'responsible for 1m babies', 2014) documents that one quarter students on Erasmus exchange scheme met their long-term partner while studying abroad. The chapter explores love, with focus on formation of intimate relations in academic exchanges in the European settings. The method is case-studies drawn from two projects based in Denmark, the first about ethnically intermarried couples (Singla, Intermarriage and mixed parenting: Promoting mental health \& wellbeing, crossover love. Palgrave Macmillan, 2015) and the second, an ongoing project about LAT (Living Apart Together) transnational couples (Singla \& Varma, LAT (Living Apart Together) transnational couples: Promoting mental health and wellbeing, 2018), moving beyond 'methodological nationalism and- conjugalism'. The theoretical framework is Cultural Psychology and foreground is a combination of Narrative Psychology, intersectionality, digital emotional reflexivity and transnationalism. Moreover, aspects related to figuring out criteria of the exchange situation abroad, which can underpin explaining the high rate of long-term relationships while studying abroad, are included. Those aspects are based on a framework, in which intercultural and developmental psychological findings are linked. The 3-4 case studies are drawn from empirical research with eight couples in the first study and 20 couples in the second. The narratives are thematically analysed, whereas two themes regarding participants' motivation for establishing relationship despite differences and long-term sustaining of the relationship are described in the chapter. Preliminary findings nuance the phenomenon of love in academic exchanges, invoking concepts such as educational homogamy, balancing independence and togetherness, diversities of connectivities intersecting social media and intimacies. Furthermore, the significant others' support and opposition of these couples' love dynamics are covered, along with considerations linked to the concept of the emotional availability (Saunders, Kraus, Barone \& Biringen, Frontiers in Psychology, 2015) based on Bowlby's attachment theory and the shared third (Benjamin, Psychoanalytic Quarterly, 73(1), 5-46, 2004). Lastly, 'good practices' for promoting the mental health and wellbeing of such academic exchange couples are delineated along with suggestions for relevant services for those experiencing psychosocial problems. Educational and cultural dimensions of transnational academic exchange such as student exchanges, double degree programmes, internships have been researched but the romantic dimensions are almost overlooked, especially qualitatively, while Green (EU's Erasmus study abroad programme is 'responsible for 1m babies', 2014) documents that one quarter students on Erasmus exchange scheme met their long-term partner while studying abroad. The chapter explores love, with focus on formation of intimate relations in academic exchanges in the European settings. The method is case-studies drawn from two projects based in Denmark, the first about ethnically intermarried couples (Singla, Intermarriage and mixed parenting: Promoting mental health \& wellbeing, crossover love. Palgrave Macmillan, 2015) and the second, an ongoing project about LAT (Living Apart Together) transnational couples (Singla \& Varma, LAT (Living Apart Together) transnational couples: Promoting mental health and wellbeing, 2018), moving beyond 'methodological nationalism and- conjugalism'. The theoretical framework is Cultural Psychology and foreground is a combination of Narrative Psychology, intersectionality, digital emotional reflexivity and transnationalism. Moreover, aspects related to figuring out criteria of the exchange situation abroad, which can underpin explaining the high rate of long-term relationships while studying abroad, are included. Those aspects are based on a framework, in which intercultural and developmental psychological findings are linked.}, language = {en} } @article{BediVisschers, author = {Bedi-Visschers, Marion}, title = {Von der hilfreichen K{\"a}tzin zum Gestiefelten Kater}, series = {Tierstudien 15/2019 : Tiere erz{\"a}hlen}, volume = {8}, journal = {Tierstudien 15/2019 : Tiere erz{\"a}hlen}, number = {15}, publisher = {Neofelis Verlag}, pages = {33 -- 44}, language = {de} } @article{RothleitnerSchlamminger, author = {Rothleitner, Christian and Schlamminger, Stephan}, title = {Invited Review Article: Measurements of the Newtonian constant of gravitation, G}, series = {Review of Scientific Instruments}, volume = {88}, journal = {Review of Scientific Instruments}, number = {11}, publisher = {AIP Publishing}, doi = {10.1063/1.4994619}, abstract = {By many accounts, the Newtonian constant of gravitation G is the fundamental constant that is most difficult to measure accurately. Over the past three decades, more than a dozen precision measurements of this constant have been performed. However, the scatter of the data points is much larger than the uncertainties assigned to each individual measurement, yielding a Birge ratio of about five. Today, G is known with a relative standard uncertainty of 4.7 x 10(-5), which is several orders of magnitudes greater than the relative uncertainties of other fundamental constants. In this article, various methods to measure G are discussed. Alarge array of different instruments ranging from the simple torsion balance to the sophisticated atom interferometer can be used to determine G. Some instruments, such as the torsion balance can be used in several different ways. In this article, the advantages and disadvantages of different instruments as well as different methods are discussed. A narrative arc from the historical beginnings of the different methods to their modern implementation is given. Finally, the article ends with a brief overview of the current state of the art and an outlook.}, language = {en} } @article{DamsSchreiner, author = {Dams, Florian and Schreiner, Rupert}, title = {Influencing factors on the sensitivity of MEMS-based thermal conductivity vacuum gauges}, series = {Journal of vacuum science \& technology A}, volume = {32}, journal = {Journal of vacuum science \& technology A}, number = {3}, publisher = {AVS}, doi = {10.1116/1.4867486}, abstract = {The measurement range of thermal conductivity vacuum gauges is mainly influenced by the sensitivity of the sensing element to variations in pressure. An enhanced definition of sensitivity shows its theoretical dependence on the geometric measures of the sensor element at the whole pressure range. This value gives the possibility of direct comparison between different types of sensor structures without the influence of the operating conditions. To study the influencing factors, sensor chips with heated surfaces in the order of some tens of mm 2 were realized by microelectromechanical systems-based fabrication techniques. By a silicon-glass hybrid process two cold planes were formed in a distance of 150 mu m above and below the heated element. The thermal conductance of devices with different geometric measures was determined in constant temperature operating mode by usage of embedded measurement equipment. In this configuration the sensor signals were sensitive to pressure in a region from 10(-5) mbar. The sensitivity was extracted by a fit of the theoretical model to the measurement data and showed the predicted dependencies on the geometric measures. (C) 2014 American Vacuum Society.}, language = {en} } @article{BetzBuecheleBruennleretal., author = {Betz, Michael A. and B{\"u}chele, Patric and Br{\"u}nnler, Manfred and Deml, Sonja and Lechner, Alfred}, title = {Silicon micro venturi nozzles for cost-efficient spray coating of thin organic P3HT/PCBM layers}, series = {Journal of micromechanics and microengineering}, volume = {27}, journal = {Journal of micromechanics and microengineering}, number = {1}, publisher = {IOP Publishing}, doi = {10.1088/0960-1317/27/1/015019}, abstract = {Improvements on spray coating are of particular interest to different fields of technology as it is a scalable deposition method and processing from solutions offer various application possibilities outside of typical facilities. When it comes to the deposition of expensive and film-forming media such as organic semiconductors, consumption and nozzle cleaning issues are of particular importance. We demonstrate the simple steps to design and fabricate micro venturi nozzles for economical spray coating with a consumption as low as 30-50 mu l.min(-1). For spray coating an active area of 25 cm(2) a 2.45-4.01 fold coating efficiency is observed compared to a conventional airbrush nozzle set. The electrical characterization of first diodes sprayed with an active layer thickness of similar to 750 nm using a single micronozzle at a coating speed of 1.7 cm(2).min(-1) reveals a good external quantum efficiency of 72.9\% at 532 nm and a dark current of similar to 7.4.10(-5) mA.cm(-2), both measured at -2 V. Furthermore, the high resistance of the micronozzles against solvents and most acids is provided through realization in a silicon wafer with silicon dioxide encapsulation, therefore allowing easy and effective cleaning.}, language = {en} } @article{LiebherrHuttererMickertetal., author = {Liebherr, Raphaela B. and Hutterer, Albert and Mickert, Matthias J. and Vogl, Franziska C. and Beutner, Andrea and Lechner, Alfred and Hummel, Helmut and Gorris, Hans H.}, title = {Three-in-one enzyme assay based on single molecule detection in femtoliter arrays}, series = {Analytical and bioanalytical chemistry}, volume = {407}, journal = {Analytical and bioanalytical chemistry}, number = {24}, publisher = {Springer}, doi = {10.1007/s00216-015-8910-0}, pages = {7443 -- 7452}, abstract = {Large arrays of femtoliter-sized chambers are important tools for single molecule research as well as bioanalytical applications. We have optimized the design and fabrication of two array types consisting of 250 × 250 (62 500) femtoliter chambers either by surface etching of fused silica slides or by polydimethylsiloxane (PDMS) molding. Highly diluted solutions of β-galactosidase were enclosed in such arrays to monitor the fluorogenic reactions of hundreds of individual enzyme molecules in parallel by wide-field fluorescence microscopy. An efficient mechanical sealing procedure was developed to prevent diffusion of the fluorescent reaction product out of the chambers. Different approaches for minimizing non-specific surface adsorption were explored. The signal acquisition was optimized to grant both a large field of view and an efficient signal acquisition from each femtoliter chamber. The optimized femtoliter array has enabled a three-in-one enzyme assay system: First, the concentration of active enzyme can be determined in a digital way by counting fluorescent chambers in the array. Second, the activity of the enzyme bulk solution is given by averaging many individual substrate turnover rates without the need for knowing the exact enzyme concentration. Third-unlike conventional enzyme assays-the distribution of individual substrate turnover rates yields insight into the conformational heterogeneity in an enzyme population. The substrate turnover rates of single β-galactosidase molecules were found to be broadly distributed and independent of the type of femtoliter array. In general, both types of femtoliter arrays are highly sensitive platforms for enzyme analysis at the single molecule level and yield consistent results.}, language = {en} } @article{RuhlWittmannKoenigetal., author = {Ruhl, Guenther and Wittmann, Sebastian and Koenig, Matthias and Neumaier, Daniel}, title = {The integration of graphene into microelectronic devices}, series = {Beilstein Journal of Nanotechnology}, volume = {8}, journal = {Beilstein Journal of Nanotechnology}, publisher = {Beilstein-Institut}, doi = {10.3762/bjnano.8.107}, pages = {1056 -- 1064}, abstract = {Since 2004 the field of graphene research has attracted increasing interest worldwide. Especially the integration of graphene into microelectronic devices has the potential for numerous applications. Therefore, we summarize the current knowledge on this aspect. Surveys show that considerable progress was made in the field of graphene synthesis. However, the central issue consists of the availability of techniques suitable for production for the deposition of graphene on dielectric substrates. Besides, the encapsulation of graphene for further processing while maintaining its properties poses a challenge. Regarding the graphene/metal contact intensive research was done and recently substantial advancements were made towards contact resistances applicable for electronic devices. Generally speaking the crucial issues for graphene integration are identified today and the corresponding research tasks can be clearly defined.}, language = {en} }