@misc{BeimlerLeisslEbneretal., author = {Beimler, Josef and Leißl, Caroline and Ebner, Lena and Elsner, Michael and M{\"u}hlbauer, Gerhard and Kohlert, Dieter and Schubert, Martin J. W. and Weiß, Andreas P. and Sterner, Michael and Raith, Thomas and Afranseder, Martin and Krapf, Tobias and Mottok, J{\"u}rgen and Siemers, Christian and Großmann, Benjamin and H{\"o}cherl, Johannes and Schlegl, Thomas and Schneider, Ralph and Milaev, Johannes and Rampelt, Christina and Roduner, Christian and Glowa, Christoph and Bachl, Christoph and Schliekmann, Claus and Gnan, Alfons and Grill, Martin and Ruhland, Karl and Piehler, Thomas and Friers, Daniel and Wels, Harald and Pflug, Kenny and Kucera, Markus and Waas, Thomas and Schlachetzki, Felix and Boy, Sandra and Pemmerl, Josef and Leis, Alexander and Welsch, Andreas F.X. and Graf, Franz and Zenger, Gerhard and Volbert, Klaus and Waas, Thomas and Scherzinger, Stefanie and Klettke, Meike and St{\"o}rl, Uta and Heyl, C. and Boldenko, A. and Monkman, Gareth J. and Kujat, Richard and Briem, Ulrich and Hierl, Stefan and Talbot, Sebastian and Schmailzl, Anton and Ławrowski, Robert Damian and Prommesberger, Christian and Langer, Christoph and Dams, Florian and Schreiner, Rupert and Valentino, Piergiorgio and Romano, Marco and Ehrlich, Ingo and Furgiuele, Franco and Gebbeken, Norbert and Eisenried, Michael and Jungbauer, Bastian and Hutterer, Albert and Bauhuber, Michael and Mikrievskij, Andreas and Argauer, Monika and Hummel, Helmut and Lechner, Alfred and Liebetruth, Thomas and Schumm, Michael and Joseph, Saskia and Reschke, Michael and Soska, Alexander and Schroll-Decker, Irmgard and Putzer, Michael and Rasmussen, John and Dendorfer, Sebastian and Weber, Tim and Al-Munajjed, Amir Andreas and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias and Haug, Sonja and Rudolph, Clarissa and Zeitler, Annika and Schaubeck, Simon and Steffens, Oliver and Rechenauer, Christian and Schulz-Brize, Thekla and Fleischmann, Florian and Kusterle, Wolfgang and Beer, Anne and Wagner, Bernd and Neidhart, Thomas}, title = {Forschungsbericht 2013}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, doi = {10.35096/othr/pub-799}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-7990}, pages = {80}, language = {de} } @article{RenkawitzWeberDullienetal., author = {Renkawitz, Tobias and Weber, Tim A. and Dullien, Silvia and Woerner, Michael and Dendorfer, Sebastian and Grifka, Joachim and Weber, Markus}, title = {Leg length and offset differences above 5 mm after total hip arthroplasty are associated with altered gait kinematics}, series = {Gait \& Posture}, volume = {vol. 49}, journal = {Gait \& Posture}, doi = {10.1016/j.gaitpost.2016.07.011}, pages = {196 -- 201}, abstract = {We aimed to investigate the relationship between postoperative leg length/offset (LL/OS) reconstruction and gait performance after total hip arthroplasty (THA). In the course of a prospective randomized controlled trial, 60 patients with unilateral hip arthrosis received cementless THA through a minimally-invasive anterolateral surgical approach. One year post-operatively, LL and global OS restoration were analyzed and compared to the contralateral hip on AP pelvic radiographs. The combined postoperative limb length/OS reconstruction of the operated hip was categorized as restored (within 5 mm) or non-restored (more than 5 mm reduction or more than 5 mm increment). The acetabular component inclination, anteversion and femoral component anteversion were evaluated using CT scans of the pelvis and the femur. 3D gait analysis of the lower extremity and patient related outcome measures (HHS, HOOS, EQ-5D) were obtained pre-operatively, six months and twelve months post-operatively by an observer blinded to radiographic results. Component position of cup and stem was comparable between the restored and non-restored group. Combined LL and OS restoration within 5 mm resulted in higher Froude number (p < 0.001), normalized walking speed (p < 0.001) and hip range-of-motion (ROM) (p = 0.004) during gait twelve months postoperatively, whereas gait symmetry was comparable regardless of LL and OS reconstruction at both examinations. Clinical scores did not show any relevant association between the accuracy of LL or OS reconstruction and gait six/twelve months after THA. In summary, postoperative LL/OS discrepancies larger than 5 mm relate to unphysiological gait kinematics within the first year after THA. DRKS00000739, German Clinical Trials Register.}, language = {en} } @article{RenkawitzWeberSpringorumetal., author = {Renkawitz, Tobias and Weber, Markus and Springorum, H.-R. and Sendtner, E. and Woerner, Michael and Ulm, K. and Weber, Tim and Grifka, Joachim}, title = {Impingement-free range of motion, cup coverage and early clinical results between femur first navigation and conventional total hip arthroplasty: a randomised controlled trial}, series = {Journal of Bone \& Joint Surgery}, volume = {97-B}, journal = {Journal of Bone \& Joint Surgery}, doi = {10.1302/0301-620X.97B7.34729}, pages = {890 -- 898}, abstract = {We report the kinematic and early clinical results of a patient- and observer-blinded randomised controlled trial in which CT scans were used to compare potential impingement-free range of movement (ROM) and acetabular component cover between patients treated with either the navigated 'femur-first' total hip arthroplasty (THA) method (n = 66; male/female 29/37, mean age 62.5 years; 50 to 74) or conventional THA (n = 69; male/female 35/34, mean age 62.9 years; 50 to 75). The Hip Osteoarthritis Outcome Score, the Harris hip score, the Euro-Qol-5D and the Mancuso THA patient expectations score were assessed at six weeks, six months and one year after surgery. A total of 48 of the patients (84\%) in the navigated 'femur-first' group and 43 (65\%) in the conventional group reached all the desirable potential ROM boundaries without prosthetic impingement for activities of daily living (ADL) in flexion, extension, abduction, adduction and rotation (p = 0.016). Acetabular component cover and surface contact with the host bone were > 87\% in both groups. There was a significant difference between the navigated and the conventional groups' Harris hip scores six weeks after surgery (p = 0.010). There were no significant differences with respect to any clinical outcome at six months and one year of follow-up. The navigated 'femur-first' technique improves the potential ROM for ADL without prosthetic impingement, although there was no observed clinical difference between the two treatment groups.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @article{WeberWeberWoerneretal., author = {Weber, Markus and Weber, Tim A. and Woerner, Michael and Craiovan, Benjamin and Worlicek, Michael and Winkler, Sebastian and Grifka, Joachim and Renkawitz, Tobias}, title = {The impact of standard combined anteversion definitions on gait and clinical outcome within one year after total hip arthroplasty}, series = {International Orthopaedics}, volume = {39}, journal = {International Orthopaedics}, number = {12}, doi = {10.1007/s00264-015-2777-8}, pages = {2323 -- 2333}, abstract = {Different target areas within the concept of combined cup and stem anteversion have been published for total hip arthroplasty (THA). We asked whether component positioning according to eight standard combined anteversion rules is associated with (1) more physiological gait patterns, (2) higher improvement of gait variables and (3) better clinical outcome after THA.In a prospective clinical study, 60 patients received cementless THA through an anterolateral MIS approach in a lateral decubitus position. Six weeks postoperatively, implant position was analysed using 3D-CT by an independent external institute. Preoperatively, six and 12 months postoperatively range of motion, normalized walking speed and hip flexion symmetry index were measured using 3D motion-capture gait analysis. Patient-related outcome measures (HHS, HOOS, EQ-5D) were obtained by an observer blinded to 3D-CT results. Eight combined anteversion definitions and Lewinnek's "safe zone" were evaluated regarding their impact on gait patterns and clinical outcome.Combined cup and stem anteversion according to standard combined anteversion definitions as well as cup placement within Lewinnek's "safe zone" did not influence range of motion, normalized walking speed and/or hip flexion symmetry index six and 12 months after THA. Similarly, increase of gait parameters within the first year after THA was comparable between all eight combined anteversion rules. Clinical outcome measures like HHS, HOOS and EQ-5D did not show any benefit for either of the combined anteversion definitions.Standard combined cup and stem anteversion rules do not improve postoperative outcome as measured by gait analysis and clinical scores within one year after THA.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @inproceedings{WeberDendorferGrifkaetal., author = {Weber, Tim and Dendorfer, Sebastian and Grifka, Joachim and Weber, Markus and W{\"o}rner, Michael and Dullien, Silvia and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Verbessert die computerassistierte Femur First Operationstechnik f{\"u}r die H{\"u}ftendoprothetik den muskuloskelettalen Lastfall auf das H{\"u}ftgelenk?}, series = {DKOU 2015, Deutscher Kongress f{\"u}r Orthop{\"a}die und Unfallchirurgie 2015}, booktitle = {DKOU 2015, Deutscher Kongress f{\"u}r Orthop{\"a}die und Unfallchirurgie 2015}, language = {de} } @article{VoellnerWeberWeberetal., author = {V{\"o}llner, Florian and Weber, Tim A. and Weber, Markus and Renkawitz, Tobias and Dendorfer, Sebastian and Grifka, Joachim and Craiovan, Benjamin}, title = {A simple method for determining ligament stiffness during total knee arthroplasty in vivo}, series = {Scientific Reports}, volume = {9}, journal = {Scientific Reports}, publisher = {Nature}, doi = {10.1038/s41598-019-41732-x}, pages = {1 -- 8}, abstract = {A key requirement in both native knee joints and total knee arthroplasty is a stable capsular ligament complex. However, knee stability is highly individual and ranges from clinically loose to tight. So far, hardly any in vivo data on the intrinsic mechanical of the knee are available. This study investigated if stiffness of the native ligament complex may be determined in vivo using a standard knee balancer. Measurements were obtained with a commercially available knee balancer, which was initially calibrated in vitro. 5 patients underwent reconstruction of the force-displacement curves of the ligament complex. Stiffness of the medial and lateral compartments were calculated to measure the stability of the capsular ligament complex. All force-displacement curves consisted of a non-linear section at the beginning and of a linear section from about 80 N onwards. The medial compartment showed values of 28.4 ± 1.2 N/mm for minimum stiffness and of 39.9 ± 1.1 N/mm for maximum stiffness; the respective values for the lateral compartment were 19.9 ± 0.9 N/mm and 46.6 ± 0.8 N/mm. A commercially available knee balancer may be calibrated for measuring stiffness of knee ligament complex in vivo, which may contribute to a better understanding of the intrinsic mechanical behaviour of knee joints.}, subject = {Biomechanische Analyse}, language = {en} } @misc{MauererRexhepajMonkmanetal., author = {Mauerer, Wolfgang and Rexhepaj, Tanja and Monkman, Gareth J. and Sindersberger, Dirk and Diermeier, Andreas and Neidhart, Thomas and Wolfrum, Dominik and Sterner, Michael and Heberl, Michael and Nusko, Robert and Maier, Georg and Nagl, Klaus and Reuter, Monika and Hofrichter, Andreas and Lex, Thomas and Lesch, Florian and Kieninger, B{\"a}rbel and Szalo, Alexander Eduard and Zehner, Alexander and Palm, Christoph and Joblin, Mitchell and Apel, Sven and Ramsauer, Ralf and Lohmann, Daniel and Westner, Markus and Strasser, Artur and Munndi, Maximilian and Ebner, Lena and Elsner, Michael and Weiß, Nils and Segerer, Matthias and Hackenberg, Rudolf and Steger, Sebastian and Schmailzl, Anton and Dostalek, Michael and Armbruster, Dominik and Koch, Fabian and Hierl, Stefan and Thumann, Philipp and Swidergal, Krzysztof and Wagner, Marcus and Briem, Ulrich and Diermeier, Andreas and Spreitzer, Stefan and Beiderbeck, Sabrina and Hook, Christian and Zobel, Martin and Weber, Tim and Groß, Simon and Penzkofer, Rainer and Dendorfer, Sebastian and Schillitz, Ingo and Bauer, Thomas and Rudolph, Clarissa and Schmidt, Katja and Liebetruth, Thomas and Hamer, Markus and Haug, Sonja and Vernim, Matthias and Weber, Karsten and Saßmannshausen, Sean Patrick and Books, Sebastian and Neuleitner, Nikolaus and Rechenauer, Christian and Steffens, Oliver and Kusterle, Wolfgang and G{\"o}mmel, Roland and Wellnitz, Felix and Stierstorfer, Johannes and Stadler, Dominik and Hofmann, Matthias J. and Motschmann, Hubert and Shamonin (Chamonine), Mikhail and Bleicher, Veronika and Fischer, Sebastian and Hackenberg, Rudolf and Horn, Anton and Kawasch, Raphael and Petzenhauser, Michael and Probst, Tobias and Udalzow, Anton and Dams, Florian and Schreiner, Rupert and Langer, Christoph and Prommesberger, Christian and Ławrowski, Robert Damian}, title = {Forschungsbericht 2016}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, doi = {10.35096/othr/pub-1384}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-13840}, language = {de} } @article{WeberDendorferBulstraetal., author = {Weber, Tim A. and Dendorfer, Sebastian and Bulstra, Sjoerd K. and Grifka, Joachim and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Gait six month and one-year after computer assisted Femur First THR vs. conventional THR. Results of a patient- and observer- blinded randomized controlled trial}, series = {Gait \& Posture}, volume = {vol. 49}, journal = {Gait \& Posture}, doi = {10.1016/j.gaitpost.2016.06.035}, pages = {418 -- 425}, abstract = {A prospective randomized controlled trial is presented that is used to compare gait performance between the computer assisted Femur First (CAS FF) operation method and conventional THR (CON). 60 patients underwent a 3D gait analysis of the lower extremity at pre-operative, 6 months post-operative and twelve months post-operative. Detailed verification experiments were facilitated to ensure the quality of data as well as to avoid over-interpreting of the data. The results confirm a similar data-quality as reported in the literature. Walking speed, range of motion and symmetry thereof improved over the follow-up period, without significant differences between the groups. While all parameters do significantly increase over the follow-up period for both groups, there were no significant differences between them at any given time-point. Patients undergoing CAS FF showed a trend to improved hip flexion angle indicating a possible long-term benefit.}, language = {en} } @misc{AuerReinkerSuessetal., author = {Auer, Simon and Reinker, Lukas and S{\"u}ß, Franz and Kubowitsch, Simone and Krutsch, Werner and Weber, Markus and Renkawitz, Tobias and Dendorfer, Sebastian}, title = {Webcast: Effect of mental demand on leg loading in highly dynamic motion}, abstract = {Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury.}, language = {en} } @article{WeberMerleNawabietal., author = {Weber, Markus and Merle, Christian and Nawabi, Danyal H. and Dendorfer, Sebastian and Grifka, Joachim and Renkawitz, Tobias}, title = {Inaccurate offset restoration in total hip arthroplasty results in reduced range of motion}, series = {Scientific Reports}, volume = {10}, journal = {Scientific Reports}, number = {13208}, publisher = {Nature}, doi = {10.1038/s41598-020-70059-1}, pages = {9}, abstract = {Offset restoration in total hip arthroplasty (THA) is associated with postoperative range of motion (ROM) and gait kinematics. We aimed to research into the impact of high offset (HO) and standard stems on postoperative ROM. 121 patients received cementless THA through a minimally-invasive anterolateral approach. A 360° hip ROM analysis software calculated impingement-free hip movement based on postoperative 3D-CTs compared to ROM values necessary for activities of daily living (ADL). The same model was then run a second time after changing the stem geometry between standard and HO configuration with the implants in the same position. HO stems showed higher ROM for all directions between 4.6 and 8.9° (p < 0.001) compared with standard stems but with high interindividual variability. In the subgroup with HO stems for intraoperative offset restoration, the increase in ROM was even higher for all ROM directions with values between 6.1 and 14.4° (p < 0.001) compared to offset underrestoration with standard stems. Avoiding offset underrestoration resulted in a higher amount of patients of over 20\% for each ROM direction that fulfilled the criteria for ADL (p < 0.001). In contrast, in patients with standard stems for offset restoration ROM did increase but not clinically relevant by offset overcorrection for all directions between 3.1 and 6.1° (p < 0.001). Offset overcorrection by replacing standard with HO stems improved ROM for ADL in a low number of patients below 10\% (p > 0.03). Patient-individual restoration of offset is crucial for free ROM in THA. Both over and underrestoration of offset should be avoided.}, language = {en} } @article{ErbWeinmannAhlborgetal., author = {Erb, Wolfgang and Weinmann, Andreas and Ahlborg, Mandy and Brandt, Christina and Bringout, Gael and Buzug, Thorsten M. and Frikel, J{\"u}rgen and Kaethner, C. and Knopp, Tobias and M{\"a}rz, T. and Moddel, Martin and Storath, Martin and Weber, A.}, title = {Mathematical analysis of the 1D model and reconstruction schemes for magnetic particle imaging}, series = {Inverse Problems}, volume = {34}, journal = {Inverse Problems}, number = {5}, publisher = {IOP Publishing}, doi = {10.1088/1361-6420/aab8d1}, abstract = {Magnetic particle imaging (MPI) is a promising new in vivo medical imaging modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response in an applied magnetic field. In this paper we provide a mathematical analysis of the modeled MPI operator in the univariate situation. We provide a Hilbert space setup, in which the MPI operator is decomposed into simple building blocks and in which these building blocks are analyzed with respect to their mathematical properties. In turn, we obtain an analysis of the MPI forward operator and, in particular, of its ill-posedness properties. We further get that the singular values of the MPI core operator decrease exponentially. We complement our analytic results by some numerical studies which, in particular, suggest a rapid decay of the singular values of the MPI operator.}, language = {en} } @inproceedings{WeberDendorferDullienetal., author = {Weber, Tim A. and Dendorfer, Sebastian and Dullien, Silvia and Grifka, Joachim and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Measuring functional outcome after total hip replacement with subject-specific hip joint loading}, series = {Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine}, volume = {226}, booktitle = {Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine}, number = {12}, doi = {10.1177/0954411912447728}, pages = {939 -- 946}, abstract = {Total hip replacement is an often-performed orthopedic surgical procedure; the amount of procedures undertaken will increase since our life expectancy is growing. In order to optimize function, hip biomechanics should be restored to as near normal as possible. The goal of this pilot study was to determine whether or not it is feasible to compute the vectorial hip reaction force pathways on the head of the prosthesis and the force angles relative to the cup of the prosthesis that occur during gait in total hip replacement patients, serving as an objective measurement of the functional outcome following hip replacement. A three-dimensional gait analysis, measuring ground reaction forces and kinematics, was performed. The data retrieved from the gait analysis was used as the input for the musculoskeletal model to compute vectorial joint reaction forces for data processing. To evaluate the position and orientation of the joint reaction forces, the force path, as well as the force angles for the operated and non-operated joint, has been calculated during the stance phase of the specific leg. The force path for subject 2 on the non-operated side is only located in the posterior-lateral quarter, as is the force path for subject 1. In contrast to this subject, the force path for subject 2 at the operated hip joint can be found only within the anterior quarter of the head of the implant, where it is nearly equally distributed in the medio-lateral half of the prosthesis head. The force-inclination angles on the cup of subject 1, with respect to the plane of the socket face, indicates that the force vector is mainly positioned in the same quadrant when compared with subject 2 (in a cup-fixed coordinate system). The force-anteversion angle behaves similarly to the force-inclination angle, even when the effects are not as pronounced. The proposed methods in this article are aiming to define two functional outcomes of total hip replacement that are related to wear and rim loading. It is accepted that wear is not only a function of time, but a function of use. Owing to the methods listed in this article, we are able to determine a) the applied force and b) the sliding distance (force pathway) in a subject-specific manner. The computed hip-reaction force angles and the distance to the rim cup are a measurement for cup or rim loading, and occurs in the so-called safe-zones. This method may well give us insight into the biomechanical situation during gait, after receiving total hip replacement, that we need to fully understand the mechanisms acting on a hip joint and to prove a possible increase of functional outcome after receiving total hip replacement.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @article{WeberAlMunajjedVerkerkeetal., author = {Weber, Tim and Al-Munajjed, Amir Andreas and Verkerke, Gijsbertus Jacob and Dendorfer, Sebastian and Renkawitz, Tobias}, title = {Influence of minimally invasive total hip replacement on hip reaction forces and their orientations}, series = {Journal of Orthopaedic Research}, volume = {32}, journal = {Journal of Orthopaedic Research}, number = {12}, doi = {10.1002/jor.22710}, pages = {1680 -- 1687}, abstract = {Minimally invasive surgery (MIS) is becoming increasingly popular. Supporters claim that the main advantages of MIS total hip replacement (THR) are less pain and a faster rehabilitation and recovery. Critics claim that safety and efficacy of MIS are yet to be determined. We focused on a biomechanical comparison between surgical standard and MIS approaches for THR during the early recovery of patients. A validated, parameterized musculoskeletal model was set to perform a squat of a 50th percentile healthy European male. A bilateral motion was chosen to investigate effects on the contralateral side. Surgical approaches were simulated by excluding the incised muscles from the computations. Resulting hip reaction forces and their symmetry and orientation were analyzed. MIS THR seemed less influential on the symmetry index of hip reaction forces between the operated and nonoperated leg when compared to the standard lateral approach. Hip reaction forces at peak loads of the standard transgluteal approach were 24\% higher on the contralateral side when compared to MIS approaches. Our results suggest that MIS THR contributes to a greater symmetry of hip reaction forces in absolute value as well as force-orientation following THR.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @inproceedings{WeberDendorferRenkawitzetal., author = {Weber, Tim and Dendorfer, Sebastian and Renkawitz, Tobias and Dullien, Silvia and Grifka, Joachim}, title = {Clinical gait analysis combined with musculoskeletal modelling - coding a new generation of evaluation instruments}, series = {Deutsche Gesellschaft f{\"u}r Biomechanik, Murnau, 2011}, booktitle = {Deutsche Gesellschaft f{\"u}r Biomechanik, Murnau, 2011}, language = {en} } @inproceedings{WeberRenkawitzGrifkaetal., author = {Weber, Tim and Renkawitz, Tobias and Grifka, Joachim and Bulstra, Sjoerd K. and Verkerke, Gijsbertus Jacob and Dendorfer, Sebastian}, title = {The musculoskeletal load scenario of computer-assisted Femur-First THR up to one year after surgery}, series = {VI International Conference on Computational Bioengineering, Barcelona, Sept. 2015}, booktitle = {VI International Conference on Computational Bioengineering, Barcelona, Sept. 2015}, language = {en} } @inproceedings{WeberDendorferBulstraetal., author = {Weber, Tim and Dendorfer, Sebastian and Bulstra, Sjoerd K. and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Biomechanical Outcome after computer-assisted vs. Conventional THR}, series = {ANSYS Conference \& 32th CADFEM Users' Meeting 2014, 04.-06. Juni, N{\"u}rnberg}, booktitle = {ANSYS Conference \& 32th CADFEM Users' Meeting 2014, 04.-06. Juni, N{\"u}rnberg}, language = {en} } @article{WeberDullienGrifkaetal., author = {Weber, Tim and Dullien, Silvia and Grifka, Joachim and Renkawitz, Tobias and Dendorfer, Sebastian}, title = {Validation of a Motion Capture Laboratory and a new marker-placement protcol for clinical applications}, series = {Gait \& Posture}, volume = {38}, journal = {Gait \& Posture}, number = {Suppl. 1}, doi = {10.1016/j.gaitpost.2013.07.229}, pages = {113 -- 114}, language = {en} } @inproceedings{WeberDullienPutzeretal., author = {Weber, Tim and Dullien, Silvia and Putzer, Michael and Dendorfer, Sebastian and Renkawitz, Tobias}, title = {Biomechanical outcome after computer-assisted vs. conventional THR - study concept and preliminary gait analysis results}, series = {GAMMA Workshop, Hannover, 2012}, booktitle = {GAMMA Workshop, Hannover, 2012}, language = {en} } @inproceedings{WeberRenkawitzBulstraetal., author = {Weber, Tim and Renkawitz, Tobias and Bulstra, Sjoerd K. and Grifka, Joachim and Verkerke, Gijsbertus Jacob and Dendorfer, Sebastian}, title = {Biomechanics of computer-assisted vs. conventional THR after one year follow up}, series = {XXV Congress of the International Society of Biomechanics, Glasgow, UK, 12th-16th July 2015}, booktitle = {XXV Congress of the International Society of Biomechanics, Glasgow, UK, 12th-16th July 2015}, language = {en} } @inproceedings{WeberDendorferBulstraetal., author = {Weber, Tim and Dendorfer, Sebastian and Bulstra, Sjoerd K. and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Musculoskeletal modeling for orthopedic surgery - Applications and chances}, series = {Orthopedics meets Engineering, Regensburg, 2015}, booktitle = {Orthopedics meets Engineering, Regensburg, 2015}, language = {en} } @article{KaesbauerSchmailzlWeberetal., author = {K{\"a}sbauer, Johannes and Schmailzl, Anton and Weber, Ulrich and Hierl, Stefan and Jaus, Tobias and Schwalme, Michael}, title = {Simulationsgest{\"u}tzte Evaluierung von Strahloszillationsmustern beim quasi-simultanen Laser-Durchstrahlschweißen}, series = {JOINING PLASTICS - F{\"u}gen von Kunststoffen}, volume = {13}, journal = {JOINING PLASTICS - F{\"u}gen von Kunststoffen}, number = {2}, pages = {102 -- 109}, language = {de} } @inproceedings{HaugSchieleWeberetal., author = {Haug, Sonja and Schiele, Agnes and Weber, Karsten and Riederer, Michael and Saller, Tobias}, title = {Nachhaltig Leben und Wirtschaften am Beispiel des Sanierungsgebiets Margaretenau Regensburg}, series = {XX. Tagung f{\"u}r Angewandte Sozialwissenschaften. Nachhaltig Leben und Wirtschaften. Management Sozialer Innovationen als Gestaltung gesellschaftlicher Transformation, 24.-26.05.2019, Hochschule M{\"u}nchen}, booktitle = {XX. Tagung f{\"u}r Angewandte Sozialwissenschaften. Nachhaltig Leben und Wirtschaften. Management Sozialer Innovationen als Gestaltung gesellschaftlicher Transformation, 24.-26.05.2019, Hochschule M{\"u}nchen}, language = {de} } @article{WeberHaugAltenbuchneretal., author = {Weber, Karsten and Haug, Sonja and Altenbuchner, Amelie and Zachmayer, Tobias}, title = {Impfbereitschaft, Impfskepsis und Impfung in der COVID-19-Pandemie}, series = {GWP - Gesellschaft. Wirtschaft. Politik}, journal = {GWP - Gesellschaft. Wirtschaft. Politik}, number = {2}, publisher = {Budrich}, doi = {10.3224/gwp.v71i2.08}, pages = {192 -- 204}, abstract = {Der Beitrag fasst sozialwissenschaftliche Erkenntnisse zur Impfbereitschaft und Impfung mit einem COVID-19 Vakzin zusammen. Diskutiert werden Impfskepsis und Einflussfaktoren wie Sozialstruktur, Verschw{\"o}rungs{\"u}berzeugungen, kollektive Verantwortung, Einstellungen zu alternativen Heilverfahren und zur Impfpflicht.}, language = {de} } @article{WeberDendorferGrifkaetal., author = {Weber, Tim A. and Dendorfer, Sebastian and Grifka, Joachim and Verkerke, Gijsbertus Jacob and Renkawitz, Tobias}, title = {Does Computer-Assisted Femur First THR Improve Musculoskeletal Loading Conditions?}, series = {BioMed Research International}, volume = {2015}, journal = {BioMed Research International}, editor = {Takagi, Michiaki}, doi = {10.1155/2015/625317}, pages = {ID 625317}, abstract = {We have developed a novel, computer-assisted operation method for minimal-invasive total hip replacement (THR) following the concept of "femur first/combined anteversion," which incorporates various aspects of performing a functional optimization of the prosthetic stem and cup position (CAS FF). The purpose of this study is to assess whether the hip joint reaction forces and patient's gait parameters are being improved by CAS FF in relation to conventional THR (CON). We enrolled 60 patients (28 CAS FF/32 CON) and invited them for gait analysis at three time points (preoperatively, postop six months, and postop 12 months). Data retrieved from gait analysis was processed using patient-specific musculoskeletal models. The target parameters were hip reaction force magnitude (hrf), symmetries, and orientation with respect to the cup. Hrf in the CAS FF group were closer to a young healthy normal. Phase-shift symmetry showed an increase in the CAS FF group. Hrf orientation in the CAS FF group was closer to optimum, though no edge or rim-loading occurred in the CON group as well. The CAS FF group showed an improved hrf orientation in an early stage and a trend to an improved long-term outcome.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @article{WeberSuessJerabeketal., author = {Weber, Markus and Suess, Franz and Jerabek, Seth and Meyer, Matthias and Grifka, Joachim and Renkawitz, Tobias and Dendorfer, Sebastian}, title = {Kinematic pelvic tilt during gait alters functional cup position in total hip arthroplasty}, series = {Journal of Orthopaedic Research}, volume = {40}, journal = {Journal of Orthopaedic Research}, number = {4}, publisher = {Wiley}, issn = {1554-527X}, doi = {10.1002/jor.25106}, pages = {846 -- 853}, abstract = {Static pelvic tilt impacts functional cup position in total hip arthroplasty (THA). In the current study we investigated the effect of kinematic pelvic changes on cup position. In the course of a prospective controlled trial postoperative 3D-computed tomography (CT) and gait analysis before and 6 and 12 months after THA were obtained in 60 patients. Kinematic pelvic motion during gait was measured using Anybody Modeling System. By fusion with 3D-CT, the impact of kinematic pelvic tilt alterations on cup anteversion and inclination was calculated. Furthermore, risk factors correlating with high pelvic mobility were evaluated. During gait a high pelvic range of motion up to 15.6° exceeding 5° in 61.7\% (37/60) of patients before THA was found. After surgery, the pelvis tilted posteriorly by a mean of 4.0 ± 6.6° (p < .001). The pelvic anteflexion led to a mean decrease of -1.9 ± 2.2° (p < .001) for cup inclination and -15.1 ± 6.1° (p < .001) for anteversion in relation to the anterior pelvic plane (APP). Kinematic pelvic changes resulted in a further change up to 2.3° for inclination and up to 12.3° for anteversion. In relation to the preoperative situation differences in postoperative cup position ranged from -4.4 to 4.6° for inclination and from -7.8 to 17.9° for anteversion, respectively. Female sex (p < .001) and normal body weight (p < .001) correlated with high alterations in pelvic tilt. Kinematic pelvic changes highly impact cup anteversion in THA. Surgeons using the APP as reference should aim for a higher anteversion of about 15° due to the functional anteflexion of the pelvis during gait.}, subject = {H{\"u}ftgelenkprothese}, language = {en} } @misc{LautenschlaegerLeisDendorferetal., author = {Lautenschl{\"a}ger, Toni and Leis, Alexander and Dendorfer, Sebastian and Palm, Christoph and Schreiner, Rupert and Langer, Christoph and Prommesberger, Christian and Ławrowski, Robert Damian and Dams, Florian and Bornmann, Benjamin and Navitski, Aliaksandr and Serbun, Pavel and M{\"u}ller, G{\"u}nter and Liebetruth, Thomas and Kohlert, Dieter and Pernsteiner, Jochen and Schreier, Franz and Heerklotz, Sabrina and Heerklotz, Allwin and Boos, Alexander and Herwald, Dominik and Monkman, Gareth J. and Treiber, Daniel and Mayer, Matthias and H{\"o}rner, Eva and Bentz, Alexander and Shamonin (Chamonine), Mikhail and Johansen, S{\o}ren Peter and Reichel, Marco and Stoll, Andrea and Briem, Ulrich and Dullien, Silvia and Renkawitz, Tobias and Weber, Tim and Dendorfer, Sebastian and Grifka, Joachim and Penzkofer, Rainer and Barnsteiner, K. and Jovanovik, M. and Wernecke, P. and V{\"o}gele, A. and Bachmann, T. and Pl{\"o}tz, Martin and Schliekmann, Claus and Wels, Harald and Helmberger, Paul and Kaspar, M. and H{\"o}nicka, M. and Schrammel, Siegfried and Enser, Markus and Schmidmeier, Monika and Schroll-Decker, Irmgard and Haug, Sonja and Gelfert, Verena and Vernim, Matthias}, title = {Forschungsbericht 2012}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, doi = {10.35096/othr/pub-783}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-7834}, pages = {64}, language = {de} } @misc{ZellmerRauberProbstetal., author = {Zellmer, Stephan and Rauber, David and Probst, Andreas and Weber, Tobias and Nagl, Sandra and R{\"o}mmele, Christoph and Schnoy, Elisabeth and Palm, Christoph and Messmann, Helmut and Ebigbo, Alanna}, title = {Verwendung k{\"u}nstlicher Intelligenz bei der Detektion der Papilla duodeni major}, series = {Zeitschrift f{\"u}r Gastroenterologie}, volume = {61}, journal = {Zeitschrift f{\"u}r Gastroenterologie}, number = {08}, publisher = {Thieme}, address = {Stuttgart}, doi = {10.1055/s-0043-1772000}, pages = {e593-e540}, abstract = {Einleitung Die Endoskopische Retrograde Cholangiopankreatikographie (ERCP) ist der Goldstandard in der Diagnostik und Therapie von Erkrankungen des pankreatobili{\"a}ren Trakts. Jedoch ist sie technisch sehr anspruchsvoll und weist eine vergleichsweise hohe Komplikationsrate auf. Ziele In der vorliegenden Machbarkeitsstudie soll gepr{\"u}ft werden, ob mithilfe eines Deep-learning-Algorithmus die Papille und das Ostium zuverl{\"a}ssig detektiert werden k{\"o}nnen und somit f{\"u}r Endoskopiker mit geringer Erfahrung ein geeignetes Hilfsmittel, insbesondere f{\"u}r die Ausbildungssituation, darstellen k{\"o}nnten. Methodik Wir betrachteten insgesamt 606 Bilddatens{\"a}tze von 65 Patienten. In diesen wurde sowohl die Papilla duodeni major als auch das Ostium segmentiert. Anschließend wurde eine neuronales Netz mittels eines Deep-learning-Algorithmus trainiert. Außerdem erfolgte eine 5-fache Kreuzvaldierung. Ergebnisse Bei einer 5-fachen Kreuzvaldierung auf den 606 gelabelten Daten konnte f{\"u}r die Klasse Papille eine F1-Wert von 0,7908, eine Sensitivit{\"a}t von 0,7943 und eine Spezifit{\"a}t von 0,9785 erreicht werden, f{\"u}r die Klasse Ostium eine F1-Wert von 0,5538, eine Sensitivit{\"a}t von 0,5094 und eine Spezifit{\"a}t von 0,9970 (vgl. [Tab. 1]). Unabh{\"a}ngig von der Klasse zeigte sich gemittelt (Klasse Papille und Klasse Ostium) ein F1-Wert von 0,6673, eine Sensitivit{\"a}t von 0,6519 und eine Spezifit{\"a}t von 0,9877 (vgl. [Tab. 2]). Schlussfolgerung In vorliegende Machbarkeitsstudie konnte das neuronale Netz die Papilla duodeni major mit einer hohen Sensitivit{\"a}t und sehr hohen Spezifit{\"a}t identifizieren. Bei der Detektion des Ostiums war die Sensitivit{\"a}t deutlich geringer. Zuk{\"u}nftig soll das das neuronale Netz mit mehr Daten trainiert werden. Außerdem ist geplant, den Algorithmus auch auf Videos anzuwenden. Somit k{\"o}nnte langfristig ein geeignetes Hilfsmittel f{\"u}r die ERCP etabliert werden.}, language = {de} } @techreport{AndratschkeCeulloDawoudetal., author = {Andratschke, Christin and Ceullo, Laura and Dawoud, Belal and Draeger, Susan and Gerdes, Thorsten and Giebisch, Matthias and Grießhammer, Peter and Haas, Katharina and Haug, Sonja and Helling, Dominik and Kominis, Lena and Lang, Christian and Malz, Sebastian and Melzl, Johannes and Michlbauer, David and M{\"u}hlberger, Thomas and Nagl, Klaus and Preis, Michael and Rechenauer, Christian and Riederer, Michael and R{\"u}ckerl, Alexander and Saller, Tobias and Schnabl, Andreas and Stadler, Michael and Steffens, Oliver and Steininger, Peter and Stelzl, Andr{\´e} and Toutouly, Lovis and Trauner, Matthias and Vetter, Miriam and Walbrunn, Johannes and Weber, Karsten and Zielbauer, Lukas}, title = {MAGGIE: Energetische Modernisierung des genossenschaftlichen Wohnquartiers Margaretenau in Regensburg}, editor = {Steffens, Oliver}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, isbn = {978-3-96256-100-0}, doi = {10.35096/othr/pub-5901}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-59011}, pages = {XVIII, 462 S.}, abstract = {Im Projekt MAGGIE wurden f{\"u}r das genossenschaftliche historische Stadtquartier „Margaretenau" in Regensburg Musterl{\"o}sungen f{\"u}r energieoptimiertes Wohnen mit innovativen Wandaufbauten aus solaraktiven Baukonstruktionen und einer vorhersagebasierten Versorgungstechnologie erforscht. Dazu wurde ein bestehendes Wohngeb{\"a}ude als Demonstrations- und Versuchsobjekt mit einem neuartigen, besonders effizienten Hybridsystem aus W{\"a}rmepumpentechnologie und Kraft- W{\"a}rme-Kopplung ausgestattet und untersucht, erg{\"a}nzt durch eine dynamische W{\"a}rmelogistik zur Verringerung von Verteilungsverlusten. Das System wurde durch ein neu entwickeltes, allgemein einsetzbares Planungs-, Optimierungs- und Steuerungstool ausgelegt und im Betrieb geregelt. Die in Echtzeit laufende Nachoptimierung des Systems w{\"a}hrend des Betriebs greift dabei auf reale Monitoringdaten zu. Die Einbindung von Nutzerbedarfsprofilen, Stromb{\"o}rse und Wetterdaten in die Steuerung gestattet einen dynamischen und perspektivischen Anlagenbetrieb zur Maximierung der Solar- und Umweltw{\"a}rme-Anteile der Energieversorgung und leistet damit einen wirksamen Beitrag zu einem emissionsarmen, klimafreundlichen Geb{\"a}udebetrieb. F{\"u}r die denkmalgerechte Modernisierung der historischen Fassaden wurde ein solaraktives und solaradaptives Außenputzsystem entwickelt und in der Realit{\"a}t getestet. Am Bestandsgeb{\"a}ude kam anstelle eines W{\"a}rmed{\"a}mmverbundsystems ein innovativer D{\"a}mmputz mit Mikrohohlglaskugeln zum Einsatz. Die Skalierbarkeit erlaubt eine abschnittsweise Modernisierung des gesamten Ensembles {\"u}ber mehrere Jahre. Durch die hohe Energieeffizienz wird die Warmmiete f{\"u}r die Bewohner der genossenschaftlichen Siedlung durch die Modernisierungsmaßnahmen nicht erh{\"o}ht, so dass auch nach der Modernisierung ein bezahlbares Wohnen sichergestellt wird.}, subject = {Altbaumodernisierung}, language = {de} } @techreport{AndratschkeCeulloDawoudetal., author = {Andratschke, Christin and Ceullo, Laura and Dawoud, Belal and Draeger, Susan and Gerdes, Thorsten and Giebisch, Matthias and Grießhammer, Peter and Haas, Katharina and Haug, Sonja and Helling, Dominik and Kominis, Lena and Lang, Christian and Malz, Sebastian and Melzl, Johannes and Michlbauer, David and M{\"u}hlberger, Thomas and Nagl, Klaus and Preis, Michael and Rechenauer, Christian and Riederer, Michael and R{\"u}ckerl, Alexander and Saller, Tobias and Schnabl, Andreas and Stadler, Michael and Steffens, Oliver and Steininger, Peter and Stelzl, Andr{\´e} and Toutouly, Lovis and Trauner, Matthias and Vetter, Miriam and Walbrunn, Johannes and Weber, Karsten and Zielbauer, Lukas}, title = {MAGGIE: Energetische Modernisierung des genossenschaftlichen Wohnquartiers Margaretenau in Regensburg}, editor = {Steffens, Oliver}, address = {Regensburg}, isbn = {978-3-96256-100-0}, doi = {10.35096/othr/pub-5335}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-53354}, pages = {XVIII, 462 S.}, abstract = {Im Projekt MAGGIE wurden f{\"u}r das genossenschaftliche historische Stadtquartier „Margaretenau" in Regensburg Musterl{\"o}sungen f{\"u}r energieoptimiertes Wohnen mit innovativen Wandaufbauten aus solaraktiven Baukonstruktionen und einer vorhersagebasierten Versorgungstechnologie erforscht. Dazu wurde ein bestehendes Wohngeb{\"a}ude als Demonstrations- und Versuchsobjekt mit einem neuartigen, besonders effizienten Hybridsystem aus W{\"a}rmepumpentechnologie und Kraft- W{\"a}rme-Kopplung ausgestattet und untersucht, erg{\"a}nzt durch eine dynamische W{\"a}rmelogistik zur Verringerung von Verteilungsverlusten. Das System wurde durch ein neu entwickeltes, allgemein einsetzbares Planungs-, Optimierungs- und Steuerungstool ausgelegt und im Betrieb geregelt. Die in Echtzeit laufende Nachoptimierung des Systems w{\"a}hrend des Betriebs greift dabei auf reale Monitoringdaten zu. Die Einbindung von Nutzerbedarfsprofilen, Stromb{\"o}rse und Wetterdaten in die Steuerung gestattet einen dynamischen und perspektivischen Anlagenbetrieb zur Maximierung der Solar- und Umweltw{\"a}rme-Anteile der Energieversorgung und leistet damit einen wirksamen Beitrag zu einem emissionsarmen, klimafreundlichen Geb{\"a}udebetrieb. F{\"u}r die denkmalgerechte Modernisierung der historischen Fassaden wurde ein solaraktives und solaradaptives Außenputzsystem entwickelt und in der Realit{\"a}t getestet. Am Bestandsgeb{\"a}ude kam anstelle eines W{\"a}rmed{\"a}mmverbundsystems ein innovativer D{\"a}mmputz mit Mikrohohlglaskugeln zum Einsatz. Die Skalierbarkeit erlaubt eine abschnittsweise Modernisierung des gesamten Ensembles {\"u}ber mehrere Jahre. Durch die hohe Energieeffizienz wird die Warmmiete f{\"u}r die Bewohner der genossenschaftlichen Siedlung durch die Modernisierungsmaßnahmen nicht erh{\"o}ht, so dass auch nach der Modernisierung ein bezahlbares Wohnen sichergestellt wird.}, subject = {Altbaumodernisierung}, language = {de} } @misc{BroserFalterŁawrowskietal., author = {Broser, Christian and Falter, Thomas and Ławrowski, Robert Damian and Altenbuchner, Amelie and V{\"o}gele, Daniel and Koss, Claus and Schlampp, Matthias and Dunnweber, Jan and Steffens, Oliver and Heckner, Markus and Jaritz, Sabine and Schiegl, Thomas and Corsten, Sabine and Lauer, Norina and Guertler, Katherine and Koenig, Eric and Haug, Sonja and Huber, Dominik and Birkenmaier, Clemens and Krenkel, Lars and Wagner, Thomas and Justus, Xenia and Saßmannshausen, Sean Patrick and Kleine, Nadine and Weber, Karsten and Braun, Carina N. and Giacoppo, Giuliano and Heinrich, Michael and Just, Tobias and Schreck, Thomas and Schnabl, Andreas and Gilmore, Amador T{\´e}ran and Roeslin, Samuel and Schmid, Sandra and Wellnitz, Felix and Malz, Sebastian and Maurial, Andreas and Hauser, Florian and Mottok, J{\"u}rgen and Klettke, Meike and Scherzinger, Stefanie and St{\"o}rl, Uta and Heckner, Markus and Bazo, Alexander and Wolff, Christian and Kopper, Andreas and Westner, Markus and Pongratz, Christian and Ehrlich, Ingo and Briem, Ulrich and Hederer, Sebastian and Wagner, Marcus and Schillinger, Moritz and G{\"o}rlach, Julien and Hierl, Stefan and Siegl, Marco and Langer, Christoph and Hausladen, Matthias and Schreiner, Rupert and Haslbeck, Matthias and Kreuzer, Reinhard and Br{\"u}ckl, Oliver and Dawoud, Belal and Rabl, Hans-Peter and Gamisch, Bernd and Schmidt, Ottfried and Heberl, Michael and G{\"a}nsbauer, Bianca and Bick, Werner and Ellermeier, Andreas and Monkman, Gareth J. and Prem, Nina and Sindersberger, Dirk and Tschurtschenthaler, Karl and Aurbach, Maximilian and Dendorfer, Sebastian and Betz, Michael A. and Szecsey, Tamara and Mauerer, Wolfgang and Murr, Florian}, title = {Forschung 2018}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, isbn = {978-3-9818209-5-9}, doi = {10.35096/othr/pub-1382}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-13826}, pages = {98}, subject = {Forschung}, language = {de} } @misc{ZellmerRauberProbstetal., author = {Zellmer, Stephan and Rauber, David and Probst, Andreas and Weber, Tobias and Braun, Georg and R{\"o}mmele, Christoph and Nagl, Sandra and Schnoy, Elisabeth and Messmann, Helmut and Ebigbo, Alanna and Palm, Christoph}, title = {Artificial intelligence as a tool in the detection of the papillary ostium during ERCP}, series = {Endoscopy}, volume = {56}, journal = {Endoscopy}, number = {S 02}, publisher = {Thieme}, address = {Stuttgart}, doi = {10.1055/s-0044-1783138}, pages = {S198}, abstract = {Aims Endoscopic retrograde cholangiopancreaticography (ERCP) is the gold standard in the diagnosis as well as treatment of diseases of the pancreatobiliary tract. However, it is technically complex and has a relatively high complication rate. In particular, cannulation of the papillary ostium remains challenging. The aim of this study is to examine whether a deep-learning algorithm can be used to detect the major duodenal papilla and in particular the papillary ostium reliably and could therefore be a valuable tool for inexperienced endoscopists, particularly in training situation. Methods We analyzed a total of 654 retrospectively collected images of 85 patients. Both the major duodenal papilla and the ostium were then segmented. Afterwards, a neural network was trained using a deep-learning algorithm. A 5-fold cross-validation was performed. Subsequently, we ran the algorithm on 5 prospectively collected videos of ERCPs. Results 5-fold cross-validation on the 654 labeled data resulted in an F1 value of 0.8007, a sensitivity of 0.8409 and a specificity of 0.9757 for the class papilla, and an F1 value of 0.5724, a sensitivity of 0.5456 and a specificity of 0.9966 for the class ostium. Regardless of the class, the average F1 value (class papilla and class ostium) was 0.6866, the sensitivity 0.6933 and the specificity 0.9861. In 100\% of cases the AI-detected localization of the papillary ostium in the prospectively collected videos corresponded to the localization of the cannulation performed by the endoscopist. Conclusions In the present study, the neural network was able to identify the major duodenal papilla with a high sensitivity and high specificity. In detecting the papillary ostium, the sensitivity was notably lower. However, when used on videos, the AI was able to identify the location of the subsequent cannulation with 100\% accuracy. In the future, the neural network will be trained with more data. Thus, a suitable tool for ERCP could be established, especially in the training situation.}, language = {en} }