@unpublished{MuellerWeiglMuellerWilliamsetal., author = {M{\"u}ller, Max and Weigl, Stefan and M{\"u}ller-Williams, Jennifer and Lindauer, Matthias and R{\"u}ck, Thomas and Jobst, Simon and Bierl, Rudolf and Matysik, Frank-Michael}, title = {Ambient methane monitoring at Hohenpeißenberg utilizing photoacoustic spectroscopy and cavity ring down spectroscopy}, doi = {10.5194/egusphere-2023-1010}, abstract = {With an atmospheric concentration of approximately 2000 parts per billion (ppbV, 10-9) methane (CH4) is the second most abundant greenhouse gas (GHG) in the atmosphere after carbon dioxide (CO2). The task of long-term and spatially resolved GHG monitoring to verify whether climate policy actions are effective, is becoming more crucial as climate change progresses. In this paper we report the CH4 concentration readings of our photoacoustic (PA) sensor over a five day period at Hohenpeißenberg, Germany. As a reference device a calibrated cavity ringdown spectrometer Picarro G2301 from the meteorological observatory was employed. Trace gas measurements with photoacoustic instruments promise to provide low detection limits at comparably low costs. However, PA devices are often susceptible to cross-sensitivities related to environmental influences. The obtained results show that relaxation effects due to fluctuating environmental conditions, e.g. ambient humidity, are a non-negligible factor in PA sensor systems. Applying algorithm compensation techniques, which are capable of calculating the influence of relaxational effects on the photoacoustic signal, increase the accuracy of the photoacoustic sensor significantly. With an average relative deviation of 1.11 \% from the G2301, the photoacoustic sensor shows good agreement with the reference instrument.}, language = {en} } @article{MuellerWeiglMuellerWilliamsetal., author = {M{\"u}ller, Max and Weigl, Stefan and M{\"u}ller-Williams, Jennifer and Lindauer, Matthias and R{\"u}ck, Thomas and Jobst, Simon and Bierl, Rudolf and Matysik, Frank-Michael}, title = {Comparison of photoacoustic spectroscopy and cavity ring-down spectroscopy for ambient methane monitoring at Hohenpeißenberg}, series = {Atmospheric Measurement Techniques}, volume = {16}, journal = {Atmospheric Measurement Techniques}, number = {18}, publisher = {Copernicus Publications}, issn = {1867-8548}, doi = {10.5194/amt-16-4263-2023}, pages = {4263 -- 4270}, abstract = {With an atmospheric concentration of approximately 2000 parts per billion (ppbV, 10-9), methane (CH4) is the second most abundant greenhouse gas (GHG) in the atmosphere after carbon dioxide (CO2). The task of long-term and spatially resolved GHG monitoring to verify whether climate policy actions are effective is becoming more crucial as climate change progresses. In this paper we report the CH4 concentration readings of our photoacoustic (PA) sensor over a 5 d period at Hohenpeißenberg, Germany. As a reference device, a calibrated cavity ring-down spectrometer, Picarro G2301, from the meteorological observatory of the German Weather Service (DWD) was employed. Trace gas measurements with photoacoustic instruments promise to provide low detection limits at comparably low costs. However, PA devices are often susceptible to cross-sensitivities related to fluctuating environmental conditions, e.g. ambient humidity. The obtained results show that for PA sensor systems non-radiative relaxation effects induced by varying humidity are a non-negligible factor. Applying algorithm compensation techniques, which are capable of calculating the influence of non-radiative relaxation effects on the photoacoustic signal, increase the accuracy of the photoacoustic sensor significantly. With an average relative deviation of 1.11 \% from the G2301, the photoacoustic sensor shows good agreement with the reference instrument.}, language = {en} } @inproceedings{CantalloubeGomezGonzalezAbsiletal., author = {Cantalloube, Faustine and Gomez-Gonzalez, Carlos and Absil, Olivier and Cantero, Carles and Bacher, Regis and Bonse, Markus and Bottom, Michael and Dahlqvist, Carl-Henrik and Desgrange, C{\´e}lia and Flasseur, Olivier and Fuhrmann, Thomas and Henning, Thomas H. and Jensen-Clem, Rebecca and Kenworthy, Matthew and Mawet, Dimitri and Mesa, Dino and Meshkat, Tiffany and Mouillet, David and M{\"u}ller, Andr{\´e} and Nasedkin, Evert and Pairet, Benoit and Pi{\´e}rard, S{\´e}bastien and Ruffio, Jean-Baptiste and Samland, Matthias and Stone, Jordan and van Droogenbroeck, Marc}, title = {Exoplanet imaging data challenge: benchmarking the various image processing methods for exoplanet detection}, series = {Adaptive Optics Systems VII : 14-22 December 2020, online only, United States}, booktitle = {Adaptive Optics Systems VII : 14-22 December 2020, online only, United States}, editor = {Schmidt, Dirk and Schreiber, Laura and Vernet, Elise}, publisher = {SPIE}, isbn = {9781510636835}, doi = {10.1117/12.2574803}, pages = {321}, abstract = {The Exoplanet Imaging Data Challenge is a community-wide effort meant to offer a platform for a fair and common comparison of image processing methods designed for exoplanet direct detection. For this purpose, it gathers on a dedicated repository (Zenodo), data from several high-contrast ground-based instruments worldwide in which we injected synthetic planetary signals. The data challenge is hosted on the CodaLab competition platform, where participants can upload their results. The specifications of the data challenge are published on our website https://exoplanet-imaging-challenge.github.io/. The first phase, launched on the 1st of September 2019 and closed on the 1st of October 2020, consisted in detecting point sources in two types of common data-set in the field of high-contrast imaging: data taken in pupil-tracking mode at one wavelength (subchallenge 1, also referred to as ADI) and multispectral data taken in pupil-tracking mode (subchallenge 2, also referred to as ADI+mSDI). In this paper, we describe the approach, organisational lessons-learnt and current limitations of the data challenge, as well as preliminary results of the participants' submissions for this first phase. In the future, we plan to provide permanent access to the standard library of data sets and metrics, in order to guide the validation and support the publications of innovative image processing algorithms dedicated to high-contrast imaging of planetary systems.}, language = {en} } @techreport{SteigerFoltanPhilippetal., type = {Working Paper}, author = {Steiger, Tamara and Foltan, Maik and Philipp, Alois and M{\"u}ller, Thomas and Gruber, Michael and Bredthauer, Andre and Krenkel, Lars and Birkenmaier, Clemens and Lehle, Karla}, title = {Accumulations of von Willebrand factor within ECMO oxygenators: Potential indicator of coagulation abnormalities in critically ill patients?}, abstract = {Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO). The composition of the clots—in particular, the presence of von Willebrand factor (vWF)—may be an indicator for prevalent nonphysiological flow conditions, foreign body reactions, or coagulation abnormalities in critically ill patients. Mats of interwoven gas exchange fibers from randomly collected MOs (PLS, Maquet, Rastatt, Germany) of 21 patients were stained with antibodies (anti-vWF and anti-P-selectin) and counterstained with 4′,6-diamidino-2-phenylindole. The extent of vWF-loading was correlated with patient and technical data. While 12 MOs showed low vWF-loadings, 9 MOs showed high vWF-loading with highest accumulations close to crossing points of adjacent gas fibers. The presence and the extent of vWF-fibers/"cobwebs," leukocytes, platelet-leukocyte aggregates (PLAs), and P-selectin-positive platelet aggregates were independent of the extent of vWF-loading. However, the highly loaded MOs were obtained from patients with a significantly elevated SOFA score, severe thrombocytopenia, and persistent liver dysfunction. The coagulation abnormalities of these critically ill patients may cause an accumulation of the highly thrombogenic and elongated high-molecular-weight vWF multimers in the plasma which will be trapped in the MOs during the ECMO therapy.}, language = {en} } @article{BirkenmaierDorniaLehleetal., author = {Birkenmaier, Clemens and Dornia, Christian and Lehle, Karla and M{\"u}ller, Thomas and Gruber, Michael and Philipp, Alois and Krenkel, Lars}, title = {Analysis of Thrombotic Deposits in Extracorporeal Membrane Oxygenators by High-resolution Microcomputed Tomography: A Feasibility Study}, series = {ASAIO Journal / American Society for Artificial Internal Organs}, volume = {66}, journal = {ASAIO Journal / American Society for Artificial Internal Organs}, number = {8}, publisher = {Lippincott Williams \& Wilkins}, issn = {1538-943X}, doi = {10.1097/MAT.0000000000001089}, pages = {922 -- 928}, abstract = {Coagulative disorders, especially clotting during extracorporeal membrane oxygenation, are frequent complications. Direct visualization and analysis of deposits in membrane oxygenators using computed tomography (CT) may provide an insight into the underlying mechanisms causing thrombotic events. However, the already established multidetector CT1 (MDCT) method shows major limitations. Here, we demonstrate the feasibility of applying industrial micro-CT (μCT) to circumvent these restrictions. Three clinically used membrane oxygenators were investigated applying both MDCT and μCT. The scans were analyzed in terms of clot volume and local clot distribution. As validation, the clot volume was also determined from the fluid volume, which could be filled into the respective used oxygenator compared to a new device. In addition, cross-sectional CT images were compared with crosscut oxygenators. Based on the μCT findings, a morphological measure (sphericity) for assessing clot structures in membrane oxygenators is introduced. Furthermore, by comparing MDCT and μCT results, an augmentation of the MDCT method is proposed, which allows for improved clot volume determination in a clinical setting.}, language = {en} } @incollection{MuellerFalter, author = {M{\"u}ller, Andreas and Falter, Thomas}, title = {Sechs F{\"u}hrungsperspektiven f{\"u}r die digitale Transformation - Welche Dashboards das Ver{\"a}nderungsmanagement in digitalen Zeiten unterst{\"u}tzen k{\"o}nnen}, series = {Arbeitskulturen im Wandel}, booktitle = {Arbeitskulturen im Wandel}, editor = {W{\"o}rwag, Sebastian and Cloots, Alexandra}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-30450-8}, doi = {10.1007/978-3-658-30451-5_12}, pages = {239 -- 257}, abstract = {W{\"a}hrend KPIs und Dashboards in großer Zahl f{\"u}r den Betrieb eines Unternehmens im eingeschwungenen Zustand zur Verf{\"u}gung stehen, scheint es insbesondere in der digitalen Transformation besonders schwierig zu sein, Orientierung zu behalten und zu vermitteln. Welche Aspekte sind dabei wichtig? Was ist der Einfluss der Unternehmenskultur? In welcher Reihenfolge sollen wir vorgehen? Wie k{\"o}nnen wir die wichtigen Parameter messen und visualisieren? Auf diese Fragen geben wir unter Ber{\"u}cksichtigung unterschiedlicher Modelle und Perspektiven Antworten und zeigen am hypothetischen Beispiel eines Autohauses m{\"o}gliche konkrete Aktionen exemplarisch auf.}, language = {de} } @techreport{BurlonEmdeHoenigetal., author = {Burlon, Thomas and Emde, Markus and H{\"o}nig, Tobias and M{\"u}ller, Cornelia and Neznanow, Arthur and Rampl, Markus and Sammut, Alexine and Schl{\"u}ßler, Kristof and Sievert Asmussen, Eva}, title = {0169 Karl-Hammerschmidt-Straße, Architekturkultur}, language = {de} } @unpublished{RueckMuellerJobstetal., author = {R{\"u}ck, Thomas and M{\"u}ller, Max and Jobst, Simon and Weigl, Stefan and Pangerl, Jonas and Bierl, Rudolf and Matysik, Frank-Michael}, title = {Digital Twin of a Photoacoustic Trace Gas Sensor for Monitoring Methane in Complex Gas Compositions}, publisher = {Elsevier / SSRN}, doi = {10.2139/ssrn.4215170}, pages = {22}, abstract = {The digitalization of industrial processes requires smart sensor systems. Photoacoustic spectroscopy is well suited for this purpose as it allows for small-sized and low-cost trace gas analysis. However, the method is susceptible to changes in measurement conditions and standard calibration routines often fail to correct for all changes. We therefore created a Digital Twin (DT) of a photoacoustic trace gas sensor for methane and evaluated it regarding variations in gas composition (CH4, N2, O2, CO2, H2O), temperature and pressure. With a mean absolute percentage error of 0.8 \% the accuracy of the sensor after DT compensation significantly exceeds the 24 \% achieved based on standard calibration in nitrogen. For the first time, we can fully analytically compute the photoacoustic signal under moderate ambient conditions with an error in the ppbV range by taking a holistic approach. Assuming knowledge of the underlying energy transfer processes, the model of this Digital Twin can be adapted to any microphone based photoacoustic sensor for monitoring any analyte species.}, language = {en} } @inproceedings{MuellerRueckJobstetal., author = {M{\"u}ller, Max and R{\"u}ck, Thomas and Jobst, Simon and Pangerl, Jonas and Bierl, Rudolf and Matysik, Frank-Michael}, title = {Creating a Digital Twin of a Photoacoustic Gas Sensor for Methane Detection in Complex Gas Matrices}, series = {Proceedings Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES): 11-15 July 2022, Vancouver, British Columbia, Canada}, booktitle = {Proceedings Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES): 11-15 July 2022, Vancouver, British Columbia, Canada}, publisher = {Optica Publishing Group}, isbn = {978-1-957171-10-4}, doi = {10.1364/LACSEA.2022.LW4D.2}, abstract = {We present the calculation results from a digital twin (DT) of our photoacoustic (PA) sensor for methane detection, regarding gas composition, temperature and pressure variations.}, language = {en} } @article{SchrollDeckerMuellerWesemann, author = {Schroll-Decker, Irmgard and M{\"u}ller, Thomas and Wesemann, Anna}, title = {Wohlbefinden von Kindern und Jugendlichen im Heim}, series = {Unsere Jugend}, volume = {61}, journal = {Unsere Jugend}, number = {11+12}, publisher = {Reinhardt}, issn = {0342-5258}, pages = {490 -- 504}, language = {de} } @unpublished{MuellerFalter, author = {M{\"u}ller, Andreas and Falter, Thomas}, title = {When Work (Re)releases Energy: Five steps towards regenerative people management}, doi = {10.13140/RG.2.2.10446.57928}, abstract = {In this article, we explore the innovative concept of regenerative work, which positions itself as a response to the challenges of the modern working world. At the core of our discussion are five phases of work design: from conventional (degenerative) work, often perceived as burdensome, through employee-oriented work, human-centeredness, restorative work, and finally to regenerative work, which can return energy to employees (and the environment). We examine the influence that leaders, employees, and HR professionals can have on designing working conditions, jobs, and teams. Practical examples illustrate how companies can achieve a positive energy balance for employees and teams through energy analysis. We emphasize that regenerative work is not a distant ideal but an achievable goal that can be realized through the conscious design of the workplace.}, language = {en} } @article{RueckMuellerJobstetal., author = {R{\"u}ck, Thomas and M{\"u}ller, Max and Jobst, Simon and Weigl, Stefan and Pangerl, Jonas and Bierl, Rudolf and Matysik, Frank-Michael}, title = {Digital Twin of a Photoacoustic Trace Gas Sensor for Monitoring Methane in Complex Gas Compositions}, series = {Sensors and Actuators B: Chemical}, journal = {Sensors and Actuators B: Chemical}, number = {378}, doi = {10.1016/j.snb.2022.133119}, abstract = {The digitalization of industrial processes requires smart sensor systems. Photoacoustic spectroscopy is well suited for this purpose as it allows for small-sized and low-cost trace gas analysis. However, the method is susceptible to changes in measurement conditions and standard calibration routines often fail to correct for all changes. We therefore created a Digital Twin (DT) of a photoacoustic trace gas sensor for methane and evaluated it regarding variations in gas composition (CH4, N2, O2, CO2, H2O), temperature and pressure. With a mean absolute percentage error of 0.8 \% the accuracy of the sensor after DT compensation significantly exceeds the 24 \% achieved based on standard calibration in nitrogen. For the first time, we can fully analytically compute the photoacoustic signal under moderate ambient conditions with an error in the ppbV range by taking a holistic approach. Assuming knowledge of the underlying energy transfer processes, the model of this Digital Twin can be adapted to any microphone based photoacoustic sensor for monitoring any analyte species.}, language = {en} } @inproceedings{MuellerDannerBreidbachetal., author = {M{\"u}ller, Stefan and Danner, Christian and Breidbach, J{\"o}rg and Seidl, Markus and Hußlein, Thomas and Lauf, Wolfgang}, title = {Stochastic Modeling of Throughput Times of Supplier Parts for an Automotive Plant}, series = {Angewandte Forschung in der Wirtschaftsinformatik - Prozesse, Technologie, Anwendungen, Systeme und Management 2014: Tagungsband zur 27. AKWI-Jahrestagung vom 07. bis zum 10.09.2014 an der Oberbayerischen Technischen Hochschule Regensburg}, booktitle = {Angewandte Forschung in der Wirtschaftsinformatik - Prozesse, Technologie, Anwendungen, Systeme und Management 2014: Tagungsband zur 27. AKWI-Jahrestagung vom 07. bis zum 10.09.2014 an der Oberbayerischen Technischen Hochschule Regensburg}, publisher = {News \& Media}, isbn = {978-3-936527-38-4}, doi = {10.15771/978-3-936527-38-4}, pages = {35 -- 43 S}, abstract = {For modern production industries optimized supply of parts is a critical success factor. Especially in the automotive industry, the reliable supply of painted bodies for the fi nal assembly is essential for OEMs considering just in time or just in sequence processes. Additionally one central cost target is the avoidance of resorting for JIT/JIS processes. An essential workfl ow analysis is therefore the basis for making strategic or operational decisions such as the adjustment of the plant structure or increasing the number of products and variants manufactured simultaneously. In order to support strategic planning using simulation and planning systems, the modeling of the production process is required. This is particularly important for scheduling as no real manufacturing data is available and therefore prognosis based on the model are essential. Due to the short time and the limited human resources for a detailed modeling, it is essential to create a robust model with good accuracy and reduced complexity}, language = {en} }