@inproceedings{HuKaboutehPawlitzaetal., author = {Hu, Rongbo and Kabouteh, Amir and Pawlitza, Katja and G{\"u}ttler, J{\"o}rg and Linner, Thomas and Bock, Thomas}, title = {Developing Personalized Intelligent Interior Units to Promote Activity and Customized Healthcare for Aging Society}, series = {Proceedings of the 36th International Symposium on Automation and Robotics in Construction (ISARC 2019), 21.05.2019-24.05.2019, Banff, Canada}, booktitle = {Proceedings of the 36th International Symposium on Automation and Robotics in Construction (ISARC 2019), 21.05.2019-24.05.2019, Banff, Canada}, editor = {Al-Hussein, Mohamed}, publisher = {The International Association for Automation and Robotics in Construction}, isbn = {978-952-69524-0-6}, doi = {10.22260/ISARC2019/0032}, pages = {234 -- 241}, abstract = {The world's population is aging at an unprecedented pace. Aging society is not only a severe crisis in the developed world such as Germany and Japan, but also a rigorous challenge in emerging economies such as China. Many age-related diseases are fostered by the lack of physical, cognitive, and social activities. Increasing the activity level has many benefits for the elderly and can improve their independence. The research project REACH (funded by European Union's Horizon 2020 Research and Innovation Program under grant agreement No. 690425) aims to develop a service system that will turn clinical and care environments into personalized modular sensing, prevention, and intervention systems that encourage the elderly to become healthy through activities (e.g., physical, cognitive, socializing, personalized food, etc.). As a core research partner, the Chair of Building Realization and Robotics at Technical University of Munich developed a series of Personalized Intelligent Interior Units (PI²Us), which are a special type of smart furniture, that materialize the REACH concepts and functionality seamlessly into the different REACH use case settings. Specifically, the design and functions of the PI²Us, which consist of the PI²U-SilverArc, PI²U-MiniArc, PI²U-Bed, and PI²U-iStander, will be described in detail. In addition, a modular apartment integrating all PI²Us and key technologies in REACH is designed and simulated to create a total interior living and care environment for elderly users. Due to its modularity, parts of the apartment can be easily adapted and rapidly deployed in different REACH use case settings in four European countries, which will then help the REACH consortium execute a series of testing activities. In conclusion, this research project provides a systematic and innovative example for the world to mitigate the impact of aging society.}, language = {en} } @inproceedings{HuLinnerWangetal., author = {Hu, Rongbo and Linner, Thomas and Wang, Suting and Cheng, Wenting and Liu, Xiaolong and G{\"u}ttler, J{\"o}rg and Zhao, Charlie and Lu, Yuan and Bock, Thomas}, title = {Towards a Distributed Intelligent Home Based on Smart Furniture for China's Aging Population}, series = {Proceedings of the 38th International Symposium on Automation and Robotics in Construction (ISARC): 02.11.2021 - 04.11.2021, Dubai, United Arab Emirates}, booktitle = {Proceedings of the 38th International Symposium on Automation and Robotics in Construction (ISARC): 02.11.2021 - 04.11.2021, Dubai, United Arab Emirates}, editor = {Feng, Chen and Linner, Thomas and Brilakis, Ioannis}, publisher = {International Association for Automation and Robotics in Construction (IAARC)}, isbn = {978-952-69524-1-3}, doi = {10.22260/ISARC2021/0008}, pages = {41 -- 48}, abstract = {Population aging is one of the major challenges facing the world. In particular, the advent of China's aging society caused by various factors will be a major threat to its future development. Therefore, serious measures need to be taken to achieve its demographic sustainability. Smart furniture can be considered as a novel subcategory of gerontechnology. One of the main outcomes of the EU-funded REACH project was a variety of smart furniture named Personalized Intelligent Interior Units (PI2Us) which served as the key component of a distributed intelligent home to promote the health and activity level of older adults. This outcome can potentially be a solution to mitigate the consequences caused by population aging. In order to understand the attitudes and opinions of Chinese older adults towards the relevant technologies, the authors conducted an opinion survey using the PI2Us as an example, which sampled more than 380 older adults in 26 out of 34 provincial-level administrative divisions of China. The survey showed that Chinese older adults in general have a highly positive attitude towards smart furniture and smart home technologies. Several other insights also can be revealed from the survey. Based on further analyses, the paper summarized why the elderly-oriented smart furniture and distributed intelligent home has the potential to thrive in China's market soon. Finally, a three-year project action plan for implementing localized solutions in cooperation with a large Chinese furniture manufacturer was presented.}, language = {en} } @techreport{AndersenHenningBojeBardramMaxhunietal., author = {Andersen, Henning Boje, and Bardram, Jakob E. and Maxhuni, Alban and Larsen, Rasmus Tolstrup and Sch{\"a}pers Barbara, and Krewer, Carmen and Steinb{\"o}ck, Martina and Sprengel, D. and Linner, Thomas and Schlandt, Marcel and Kabouteh, Amir and G{\"u}ttler, J{\"o}rg and Hu, Rongbo and Lu, Yuan and Bock, Thomas}, title = {Detailed set of privacy guidelines and schemata: Summarization of the outcome of the development of necessary data privacy and security schemata to (1) protect sensed data; (2) ascertain computational anonymity; (3) ensure privileged intervention access}, abstract = {Deliverable D32: Detailed set of privacy guidelines and schemata Responsive Engagement of the Elderly promoting Activity and Customized Healthcare 2 Deliverable D32: Detailed set of privacy guidelines and schemata: Summarization of the outcome of the development of necessary data privacy and security schemata to (1) protect sensed data; (2) ascertain computational anonymity; (3) ensure privileged intervention access (associated with task T.7.5). Abstract: This deliverable report examines the outcomes of the REACH research project with regard to data privacy and data security, associated with Task T7.5. This document gives an overview of our analyses involving ethics and privacy concerns in terms of the individual touchpoints and shows how these findings guided the project towards the determination of the medical purpose and intended use-cornerstones to on the path to market entry. In addition, we provide a brief overview of how the guidelines regarding data protection and encryption influenced the technical design and implementation of project components. Furthermore, we provide an update on the management of legal implications (and the implications resulting from this for system requirements and business strategy) of the use of machine learning and artificial intelligence in the context of REACH solutions, incorporating an external expert opinion. Finally, this deliverable report contains a summary of our approach towards risk gov-ernance and standardization in this regard: our work in REACH on privacy and security schemata, culminated in a CEN Workshop Agreement (guideline) that generalizes REACH outcomes and makes them accessible and usable beyond the REACH consortium .}, language = {en} } @article{HuLinnerTrummeretal., author = {Hu, Rongbo and Linner, Thomas and Trummer, Julian and G{\"u}ttler, J{\"o}rg and Kabouteh, Amir and Langosch, Katharina and Bock, Thomas}, title = {Developing a Smart Home Solution Based on Personalized Intelligent Interior Units to Promote Activity and Customized Healthcare for Aging Society}, series = {Journal of Population Ageing: Special Issue on responsive engagement of older persons promoting activity and customized healthcare}, volume = {13}, journal = {Journal of Population Ageing: Special Issue on responsive engagement of older persons promoting activity and customized healthcare}, number = {1}, publisher = {Springer Nature}, doi = {10.1007/s12062-020-09267-6}, pages = {257 -- 280}, abstract = {The world's population is aging at an unprecedented pace. Aging society is not only a severe crisis in the developed world, but also a rigorous challenge in emerging economies. Many age-related diseases are fostered by the lack of physical, cognitive, and social activities. Increasing the activity level has many benefits for the elderly and can improve their independence. Based on the analysis of the state-of-the-art and shortcomings of the current smart home solutions, the EU-funded research project REACH aims to develop a service system that will turn clinical and care environments into personalized modular sensing, prevention, and intervention systems that encourage the elderly to become healthy through various activities. To achieve that goal, the research team developed a series of smart furniture (PI2Us) that materialize the research concepts and functionality seamlessly into the various environments. Specifically, the development process and the functionality testing results of the PI2Us are reported in detail. In addition, a simulated smart home solution concept (TRACK) integrating key assistive technologies developed is proposed to create a comprehensive interior living and care environment for elderly users. Due to its modularity and flexibility, the partial or entire solution can be easily adapted and rapidly deployed in different use case settings in Europe, which allows the project consortium to execute different testing activities. In the next phase, the research team will focus on enhancing the usability and performance of the prototypes in order to eventually push them to the market. In conclusion, this research provides an innovative smart home solution for the industry to mitigate the impact of aging society.}, language = {en} } @inproceedings{HuLinnerSchmailzletal., author = {Hu, Rongbo and Linner, Thomas and Schmailzl, Marc and G{\"u}ttler, J{\"o}rg and Lu, Yuan and Bock, Thomas}, title = {Exploring Gerontechnology for Aging-Related Diseases in Design Education: An Interdisciplinary Perspective}, series = {Proceedings of the 37th International Symposium on Automation and Robotics in Construction (ISARC 2020): From Demonstration to Practical Use, To New Stage of Construction Robot, October 27-28, 2020, Kitakyushu, Japan}, booktitle = {Proceedings of the 37th International Symposium on Automation and Robotics in Construction (ISARC 2020): From Demonstration to Practical Use, To New Stage of Construction Robot, October 27-28, 2020, Kitakyushu, Japan}, editor = {Tateyama, Kazuyoshi and Ishii, Kazuo and Inoue, Fumihiro}, publisher = {The International Association for Automation and Robotics in Construction (I.A.A.R.C.)}, isbn = {978-952-94-3634-7}, doi = {10.22260/ISARC2020/0102}, pages = {735 -- 742}, abstract = {Aging society is not only a crisis in the developed world but also a severe challenge in some emerging economies. However, the awareness of population aging and gerontechnology is far from sufficiently addressed in the architectural design education in universities. Therefore, an interdisciplinary approach in design education is urgently needed to raise the awareness of the aging crisis among the future architects, interior designers, and beyond. This article introduces a novel model of a design seminar offered by a German University, addressing population aging issues in the architecture department. The syllabus, formality, and the expected results of the seminar are revealed in detail. The participants are encouraged to apply interdisciplinary knowledge such as barrier-free architecture, mechanical engineering, electrical engineering, robotics, medicine, psychology, and business to achieve the goals of the seminar. Based on the originality and degree of completion, several students' works are selected and reported, targeting a variety of diseases or syndromes related to aging, such as dementia, immobility, and tremors. Overall, participants of this seminar are motivated and have positive feedback on this seminar, oftentimes claiming that they have seldom studied similar topics in previous architecture education. This enables students from architecture as well as other fields to be better prepared to tackle the upcoming challenges such as labor shortages and infectious diseases in a rapidly aging world. Furthermore, the seminar creates novel concepts that serve as a win-win "honeypot" for both students and their instructors, potentially sparking research topics and start-ups with concepts fostered in this seminar.}, language = {en} } @incollection{LinnerSchmailzlBocketal., author = {Linner, Thomas and Schmailzl, Marc and Bock, Thomas and Hu, Rongbo and G{\"u}ttler, J{\"o}rg}, title = {Active Assisted Living Technology in the Context of the Built Environment}, series = {The Routledge Companion to Ecological Design Thinking: Healthful Ecotopian Visions for Architecture and Urbanism}, booktitle = {The Routledge Companion to Ecological Design Thinking: Healthful Ecotopian Visions for Architecture and Urbanism}, publisher = {Routledge}, address = {New York}, doi = {10.4324/9781003183181-50}, pages = {10}, language = {en} } @article{WesselyHausleiterMichaelisetal., author = {Wessely, Rainer and Hausleiter, J{\"o}rg and Michaelis, Cornelia and Jaschke, Birgit and Vogeser, Michael and Milz, Stefan and Behnisch, Boris and Schratzenstaller, Thomas and Renke-Gluszko, Magdalena and St{\"o}ver, Michael and Wintermantel, Erich and Kastrati, Adnan and Sch{\"o}mig, Albert}, title = {Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating}, series = {Arteriosclerosis, Thrombosis, and Vascular Biology}, volume = {25}, journal = {Arteriosclerosis, Thrombosis, and Vascular Biology}, number = {4}, issn = {1524-4636}, doi = {10.1161/01.ATV.0000157579.52566.ee}, pages = {748 -- 753}, abstract = {Objective The risk of in-stent restenosis can be considerably reduced by stents eluting cytostatic compounds. We created a novel drug-eluting stent system that includes several new features in the rapidly evolving field of stent-based drug delivery. Methods and Results The aim of the present study was the preclinical evaluation of a stent-coating system permitting individual, on-site coating of stents with a unique microporous surface allowing for individualizable, dose-adjustable, and multiple coatings with identical or various compounds, designated ISAR (individualizable drug-eluting stent system to abrogate restenosis). Stents were coated with 0.75\% rapamycin solution, and high-performance liquid chromatography (HPLC)-based determination of drug release profile indicated drug release for >21 days. Rapamycin-eluting microporous (REMP) stents implanted in porcine coronary arteries were safe. To determine the efficacy of REMP stents, this novel drug-eluting stent platform was compared with the standard sirolimus-eluting stent. At 30 days, in-stent neointima formation in porcine coronary arteries was similar in both groups, yielding a significant decrease of neointimal area and injury-dependent neointimal thickness compared with bare-metal stents. Conclusion The ISAR drug-eluting stent platform as a novel concept for stent coating allows for a safe, effective, on-site stent coating process, thus justifying further clinical evaluation to decrease in-stent restenosis in humans. In-stent neointima formation can be successfully attenuated by drug-eluting stents. We introduce a novel conceptual approach for stent-coating that allows for dose-adjustable, on-site stent coating process if desired with multiple compounds. Microporous stents coated with rapamycin proved safe and effective for the limitation of neointima formation in a porcine coronary stent model.}, language = {en} } @article{HausleiterKastratiWesselyetal., author = {Hausleiter, J{\"o}rg and Kastrati, Adnan and Wessely, Rainer and Dibra, Alban and Mehilli, Julinda and Schratzenstaller, Thomas and Graf, Isolde and Renke-Gluszko, Magdalena and Behnisch, Boris and Dirschinger, Josef and Wintermantel, Erich and Sch{\"o}mig, Albert}, title = {Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating}, series = {European Heart Journal - Clinical research}, volume = {26}, journal = {European Heart Journal - Clinical research}, number = {15}, doi = {10.1093/eurheartj/ehi405}, pages = {1475 -- 1481}, abstract = {Aims Drug-eluting stents (DES) represent a major advance in interventional cardiology. Along with the success shown, current DES also present limitations related to the presence of polymer-coating, fixed drug, and dose used. With the ISAR (Individualized Drug-Eluting Stent System to Abrogate Restenosis) project, a DES system has been developed that permits individualized choice of the drug and dose to use for the given patient. The objective of this prospective dose finding study was to assess the feasibility, safety, and efficacy of a polymer-free on-site stent coating with increasing rapamycin doses. Methods and results In this dose finding study, 602 patients were sequentially enrolled in four groups: microporous bare metal stent (BMS), DES stents coated with a 0.5, 1.0, and 2.0\% rapamycin solution. The angiographic in-segment restenosis rate at follow-up angiography was the primary study endpoint. In-segment restenosis was significantly reduced from 25.9\% with BMS to 18.9, 17.2, and 14.7\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.024). Similarly, the need for target lesion revascularization at 1 year follow-up was reduced from 21.5\% with BMS to 16.4, 12.6, and 8.8\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.006). Conclusion The placement of polymer-free stents coated on-site with rapamycin is feasible and safe. Furthermore, a dose-dependent efficacy in restenosis prevention is achievable with this new DES concept.}, language = {en} } @techreport{KaboutehGuettlerLinneretal., author = {Kabouteh, Amir and G{\"u}ttler, J{\"o}rg and Linner, Thomas and Valk, Carlijn and Lu, Yuan and Kozak, Dominika}, title = {Final mock-up version of REACH system}, abstract = {In REACH, WP6 focusses on systems engineering and testing aspects such as system integration, verification, validation, and optimization. The presented Deliverable (associated with Task T6.2) provides a presentation/demonstration of the executed trials including different partner groups in different use case settings. It is worth mentioning that since this deliverable report has a nature of "Demonstrator", this document tries to show the implemented trials. Therefore, it was tried to integrate as many pictures as possible to prove the trials. This deliverable report targets mainly the Touchpoints TP1, TP2 and TP3. This is decided due to the person months of the partners involved in this task. In these trials the partners addressed a pre-integration of sub modules involved in the future REACH presentation. Additionally, this deliverable discusses the trials from the first step which is the planning and execution, then to the execution/implementation and then to analysis and studying the results. Furthermore, using these trials the deficiencies and shortcomings were identified in these lab experimentations. Early detection of shortcomings and deficiencies will lead to simplified implementation and adjustment before reaching the final testing and integration stages. At the current time, the partners are already planning and preparing for the future tests/trials at the use case settings sites. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 690425.}, language = {en} } @article{SchildgenJoergDossingeretal., author = {Schildgen, Johannes and J{\"o}rg, Thomas and Dossinger, Manuel and Deßloch, Stefan}, title = {Marimba: A framework for making MapReduce jobs incremental}, series = {Proceedings - 2014 IEEE International Congress on Big Data, BigData Congress 2014, 27 June 2014 - 02 July 2014, Anchorage, AK, USA}, journal = {Proceedings - 2014 IEEE International Congress on Big Data, BigData Congress 2014, 27 June 2014 - 02 July 2014, Anchorage, AK, USA}, publisher = {IEEE}, doi = {10.1109/BigData.Congress.2014.27}, abstract = {Many MapReduce jobs for analyzing Big Data require many hours and have to be repeated again and again because the base data changes continuously. In this paper we propose Marimba, a framework for making MapReduce jobs incremental. Thus, a recomputation of a job only needs to process the changes since the last computation. This accelerates the execution and enables more frequent recomputations, which leads to results which are more up-to-date. Our approach is based on concepts that are popular in the area of materialized views in relational database systems where a view can be updated only by aggregating changes in base data upon the previous result.}, language = {en} }