@misc{LautenschlaegerLeisDendorferetal., author = {Lautenschl{\"a}ger, Toni and Leis, Alexander and Dendorfer, Sebastian and Palm, Christoph and Schreiner, Rupert and Langer, Christoph and Prommesberger, Christian and Ɓawrowski, Robert Damian and Dams, Florian and Bornmann, Benjamin and Navitski, Aliaksandr and Serbun, Pavel and M{\"u}ller, G{\"u}nter and Liebetruth, Thomas and Kohlert, Dieter and Pernsteiner, Jochen and Schreier, Franz and Heerklotz, Sabrina and Heerklotz, Allwin and Boos, Alexander and Herwald, Dominik and Monkman, Gareth J. and Treiber, Daniel and Mayer, Matthias and H{\"o}rner, Eva and Bentz, Alexander and Shamonin (Chamonine), Mikhail and Johansen, S{\o}ren Peter and Reichel, Marco and Stoll, Andrea and Briem, Ulrich and Dullien, Silvia and Renkawitz, Tobias and Weber, Tim and Dendorfer, Sebastian and Grifka, Joachim and Penzkofer, Rainer and Barnsteiner, K. and Jovanovik, M. and Wernecke, P. and V{\"o}gele, A. and Bachmann, T. and Pl{\"o}tz, Martin and Schliekmann, Claus and Wels, Harald and Helmberger, Paul and Kaspar, Marcel and H{\"o}nicka, M. and Schrammel, Siegfried and Enser, Markus and Schmidmeier, Monika and Schroll-Decker, Irmgard and Haug, Sonja and Gelfert, Verena and Vernim, Matthias}, title = {Forschungsbericht 2012}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, doi = {10.35096/othr/pub-783}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-7834}, pages = {64}, language = {de} } @article{EnglertAngeleFierlbecketal., author = {Englert, Carsten and Angele, Peter and Fierlbeck, J. and Dendorfer, Sebastian and Schubert, T. and M{\"u}ller, R. and Lienhard, S. and Zellner, Johannes and Nerlich, Michael and Neumann, Carsten}, title = {Conductive bone substitute material with variable antibiotic delivery}, series = {Der Unfallchirurg}, volume = {110}, journal = {Der Unfallchirurg}, number = {5}, publisher = {Springer}, doi = {10.1007/s00113-007-1229-3}, pages = {408 -- 413}, abstract = {A new bone substitute, consisting of hydroxylapatite and calcium sulphate, was prepared in two formulations and analysed for its mechanical strength and antibiotic elution.The bone substitute PerOssal has osteoconductive and degradable properties. The material has a built-in capillary structure, which results in an immediate fluid uptake. Antibiotics absorbed to the bone substitute resulted in a prolonged release rate. Mechanical strength was investigated by an unconfined compression test up to failure under both wet and dry conditions for both formulations of the bone substitute. Antibiotic release was analysed microbiologically for two antibiotics, vancomycin and gentamicin, over an elution period of 10 days using the agar diffusion method.The drug release analysis resulted in a prolonged release rate of both antibiotics over 10 days. In vitro the amount of gentamicin and vancomycin eluted at day 10. From one pellet still exceeded the minimal inhibitory concentration of most aetiologically important pathogens. Formulation two of the present bone substitute is significantly harder in both wet and dry conditions when compared to formulation one. Both formulations lose strength in the wet condition relative to their performance in the dry condition. However, formulation two is as hard under wet conditions as formulation one is when dry.PerOssal is a suitable new degradable osteoconductive bone substitute that can be loaded with antibiotic solutions, which are released in effective doses over 10 days. The mechanical strength of PerOssal is sufficient to support cancellous bone defects in non-weight-bearing areas or in combination with osteosynthesis.}, subject = {Knochenersatz}, language = {en} } @article{KleinNabbefeldHattabetal., author = {Klein, C. and Nabbefeld, T. and Hattab, H. and Meyer, D. and Jnawali, G. and Kammler, Martin and Meyer zu Heringdorf, Frank-Joachim and Golla-Franz, A. and M{\"u}ller, B. H. and Schmidt, Thomas and Henzler, M. and Horn-von Hoegen, Michael}, title = {Lost in reciprocal space? Determination of the scattering condition in spot profile analysis low-energy electron diffraction}, series = {Review of scientific instruments}, volume = {82}, journal = {Review of scientific instruments}, number = {3}, publisher = {American Institute of Physics}, doi = {10.1063/1.3554305}, abstract = {The precise knowledge of the diffraction condition, i.e., the angle of incidence and electron energy, is crucial for the study of surface morphology through spot profile analysis low-energy electron diffraction (LEED). We demonstrate four different procedures to determine the diffraction condition: employing the distortion of the LEED pattern under large angles of incidence, the layer-by-layer growth oscillations during homoepitaxial growth, a G(S) analysis of a rough surface, and the intersection of facet rods with 3D Bragg conditions.}, language = {en} }