@inproceedings{WindbuehlerOkkesimChristetal., author = {Windb{\"u}hler, Anna and Okkesim, S{\"u}kr{\"u} and Christ, Olaf and Mottaghi, Soheil and Rastogi, Shavika and Schmuker, Michael and Baumann, Timo and Hofmann, Ulrich G.}, title = {Machine Learning Approaches to Classify Anatomical Regions in Rodent Brain from High Density Recordings}, series = {44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2022): 11-15 July 2022, Glasgow, Scotland, United Kingdom}, booktitle = {44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2022): 11-15 July 2022, Glasgow, Scotland, United Kingdom}, publisher = {IEEE}, doi = {10.1109/EMBC48229.2022.9871702}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-35296}, pages = {3530 -- 3533}, abstract = {Identifying different functional regions during a brain surgery is a challenging task usually performed by highly specialized neurophysiologists. Progress in this field may be used to improve in situ brain navigation and will serve as an important building block to minimize the number of animals in preclinical brain research required by properly positioning implants intraoperatively. The study at hand aims to correlate recorded extracellular signals with the volume of origin by deep learning methods. Our work establishes connections between the position in the brain and recorded high-density neural signals. This was achieved by evaluating the performance of BLSTM, BGRU, QRNN and CNN neural network architectures on multisite electrophysiological data sets. All networks were able to successfully distinguish cortical and thalamic brain regions according to their respective neural signals. The BGRU provides the best results with an accuracy of 88.6 \% and demonstrates that this classification task might be solved in higher detail while minimizing complex preprocessing steps.}, language = {en} } @techreport{GerhardsWeberKlafkaetal., author = {Gerhards, Christoph and Weber, Urban and Klafka, Peter and Golla, Stefan and Hagedorn, Gregor and Baumann, Franz and Brendel, Heiko and Breyer, Christian and Clausen, Jens and Creutzig, Felix and Daub, Claus-Heinrich and Helgenberger, Sebastian and Hentschel, Karl-Martin and von Hirschhausen, Christian and Jordan, Ulrike and Kemfert, Claudia and Krause, Harald and Linow, Sven and Oei, Pao-Yu and Pehnt, Martin and Pfennig, Andreas and Pr{\"a}ger, Fabian and Quaschning, Volker and Schneider, Jens and Spindler, Uli and Stelzer, Volker and Sterner, Michael and Wagener-Lohse, Georg and Weinsziehr, Theresa}, title = {Klimavertr{\"a}gliche Energieversorgung f{\"u}r Deutschland - 16 Orientierungspunkte}, series = {Diskussionsbeitr{\"a}ge der Scinetists for Future ; 7}, journal = {Diskussionsbeitr{\"a}ge der Scinetists for Future ; 7}, doi = {10.5281/zenodo.4409334}, abstract = {Als fairer Beitrag Deutschlands zur Einhaltung der globalen 1,5-Grad-Grenze werden 16 Orientierungspunkte f{\"u}r eine klimavertr{\"a}gliche Energieversorgung vorgestellt. Es wird davon ausgegangen, dass hierf{\"u}r die deutschen energiebedingten CO2-Emissio­nen in etwa 15 Jahren weitgehend auf Null sinken m{\"u}ssen. Energieeinsparung hilft, den notwendigen Ausbau von regenerativen Erzeugungskapazit{\"a}ten zu verringern. Der Verkehrssektor kann ebenso wie die Bereiche Prozess- und Geb{\"a}udew{\"a}rme hier­zu wesentlich beitragen. Die Kernenergie ist mit großen Risiken belastet und kann nicht hinreichend schnell aufgebaut werden. Biomasse in Form von Energie­pflan­zen zu nutzen, ist ineffizient und steht im Konflikt mit anderen Arten der Land­nut­zung. Importe klimaneutral erzeugter Energietr{\"a}ger in sehr großem Umfang er­for­dern extrem große Investitionen im Ausland. Sie sind eine ungesicherte Option auf die Zukunft. Entscheidend ist daher der ausreichend schnelle Ausbau von Photovoltaik (PV) und Wind­kraft in Deutschland. Sch{\"a}tzungsweise kann der Elektrizit{\"a}tsbedarf im Jahr 2030 z.B. durch den Ausbau auf ca. 350 GW PV und ca. 150 GW Windkraft nahe­zu voll­st{\"a}ndig regenerativ gedeckt werden. Damit ließe sich eine zum großen Teil elek­tri­fizierte Mobilit{\"a}t und W{\"a}rmeversorgung betreiben und ein Teil des ben{\"o}­tig­ten "gr{\"u}­nen" Wasserstoffs in Deutschland bereitstellen. Hierf{\"u}r ist ein j{\"a}hr­licher Zu­bau von durchschnittlich ca. 30 GW PV und ca. 9 GW Windkraft n{\"o}tig. Dies ist ca. sechs- (PV) bzw. dreimal (Wind) so hoch wie bisher vorgesehen und verlangt eine ge­sell­schaft­liche Kraftanstrengung. Ein weiter verz{\"o}gerter Ausbau m{\"u}sste mit noch deut­lich gr{\"o}ßeren gesellschaftlichen Anstrengungen f{\"u}r drastische Energieeinspa­run­gen oder Importe erneuerbarer Energie ausgeglichen werden. Insgesamt k{\"o}nnte dies noch deutlich schwieriger zu realisieren sein, als ein ambitionierter Ausbau. Da der Auf­bau der Kapazit{\"a}ten mehrere Jahre erfordert, ist es m{\"o}glich nachzusteuern, z. B. wenn erkennbar wird, dass sich ein ausreichend großer globaler Markt f{\"u}r Importe ent­wi­ckelt. Bis dahin ist es aus Verantwortung gegen­{\"u}ber der Zukunft und im Sinne des Pariser Vertrages empfehlenswert, die hier genannten Ausbauziele zu verfol­gen. Gr{\"u}ner, also aus erneuerbaren Energien hergestellter Wasserstoff und daraus abge­lei­tete Syntheseprodukte sind f{\"u}r die Dekarbonisierung von Industrieprozessen, den Flug- und Schiffsverkehr sowie f{\"u}r die Absicherung der Energieversorgung bei Dun­kel­flauten n{\"o}tig. Ohne die genannten Ausbauziele f{\"u}r Wind und Solar noch drastisch weiter zu erh{\"o}hen, stehen diese Produkte f{\"u}r Straßenverkehr und W{\"a}rmeversor­gung jedoch nicht in ausreichenden Mengen zur Verf{\"u}gung. Techniken zum Aus­gleich zwischen Elektrizit{\"a}tsangebot und -nachfrage sind verf{\"u}gbar und sollten recht­zeitig auf- bzw. ausgebaut werden. Hierzu geh{\"o}ren: Stromaustausch mit den Nach­barl{\"a}ndern, Flexibilisierung des Verbrauchs und Energiespeicherung. F{\"u}r deren Inte­gration sowie den Ausbau der Netze sollten z{\"u}gig verbesserte rechtliche Rah­men­bedingungen geschaffen werden. Die Kosten eines klimavertr{\"a}glichen Energiesystems sind mittel- bis langfristig nicht h{\"o}­her als im derzeitigen System. Gleichzeitig entstehen Arbeitspl{\"a}tze und Export­chan­cen durch Aufbau, Betrieb und Wartung einer regenerativen Energieversorgung in Deutschland und die energetische Geb{\"a}udesanierung. Die politischen Rahmenbe­din­gungen entscheiden, ob eine klimavertr{\"a}gliche Energieversorgung Deutschlands ge­lingt.}, language = {de} } @inproceedings{BoeseErmertTunayaretal., author = {B{\"o}se, Holger and Ermert, Helmut and Tunayar, A. and Monkman, Gareth J. and Baumann, Michael and Kahled, W. and Reichling, S. and Bruhns, Otto T. and Freimuth, Herbert and Egersd{\"o}rfer, Stefan}, title = {A novel haptic sensor-actuator system for virtual reality}, series = {Eurohaptics 2004, Munich, Germany, June 5 - 7, 2004 Proceedings of the 4th International Conference EuroHaptics 2004 ; June 5 - 7, 2004, M{\"u}nchen, Germany}, booktitle = {Eurohaptics 2004, Munich, Germany, June 5 - 7, 2004 Proceedings of the 4th International Conference EuroHaptics 2004 ; June 5 - 7, 2004, M{\"u}nchen, Germany}, publisher = {Inst. of Automatic Control Engineering}, address = {M{\"u}nchen}, isbn = {3-9809614-0-0}, language = {en} } @inproceedings{BoeseErmertTunayaretal., author = {B{\"o}se, Holger and Ermert, Helmut and Tunayar, A. and Monkman, Gareth J. and Baumann, Michael and Kahled, W. and Reichling, S. and Bruhns, Otto T. and Freimuth, Herbert and Egersd{\"o}rfer, Stefan}, title = {A Novel Haptic Sensor-Actuator System for Applications in Virtual Reality}, series = {BMBF-Tagung, Leipzig 19.10 February 2004}, booktitle = {BMBF-Tagung, Leipzig 19.10 February 2004}, language = {en} } @inproceedings{BoeseMonkmanFreimuthetal., author = {B{\"o}se, Holger and Monkman, Gareth J. and Freimuth, Herbert and Klein, Dagmar and Ermert, Helmut and Baumann, Michael and Egersd{\"o}rfer, Stefan and Bruhns, Otto T.}, title = {ER Fluid Based Haptic System for Virtual Reality}, series = {Actuator 2002 : 8th International Conference on New Actuators \& 2nd International Exhibition on Smart Actuators and Drive Systems ; Bremen, Germany, 10 - 12 June 2002}, booktitle = {Actuator 2002 : 8th International Conference on New Actuators \& 2nd International Exhibition on Smart Actuators and Drive Systems ; Bremen, Germany, 10 - 12 June 2002}, edition = {CD-ROM}, pages = {351 -- 354}, language = {en} } @inproceedings{KhaledBruhnsReichlingetal., author = {Khaled, W. and Bruhns, Otto T. and Reichling, S. and B{\"o}se, Holger and Baumann, Michael and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and Klein, Dagmar and Freimuth, Herbert and Ermert, Helmut}, title = {A haptic system for virtual reality applications based on ultrasound elastography and electrorheological fluids}, series = {Acoustical Imaging (ACIM)}, volume = {27}, booktitle = {Acoustical Imaging (ACIM)}, publisher = {Springer}, address = {Dordrecht}, isbn = {978-90-481-6652-7}, issn = {0270-5117}, doi = {10.1007/978-1-4020-2402-3_85}, pages = {667 -- 674}, abstract = {Mechanical properties of biological tissue represent important diagnostic information and are of histological and pathological relevance. Malignant tumors are significantly stiffer and more immobile than surrounding healthy tissue. Hard calcifications in vessels occur due to arteriosclerosis. The problem is, that such information is usually not available or can only be obtained by manual palpation, which is subjective and limited in sensitivity. It requires intuitive assessment and does not allow quantitative documentation. Unfortunately, none of the established medical imaging equipment such as magnetic resonance imaging (MRI) or X-ray computed tomography (CT) can provide direct measure of tissue elasticity. On the one hand a suitable sensor is required for quantitative measurement of mechanical tissue properties. On the other hand there is also some need for a realistic haptic display of such tissue properties. Suitable actuator arrays with high spatial resolution acting in real time are required. A haptic sensor actuator system is presented in this paper including a sensitive sensor part and an actuator array for different applications. The mechanical consistency of an object is to be locally specified using a sensor system and represented perceptibly in a remote position on an actuator system for the user. The sensor system uses ultrasound (US) elastography, whereas the actuator array is based on electrorheological (ER) fluids.}, language = {en} } @inproceedings{KhaledBruhnsReichlingetal., author = {Khaled, W. and Bruhns, Otto T. and Reichling, S. and B{\"o}se, Holger and Baumann, Michael and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and Klein, Dagmar and Freimuth, Herbert and Ermert, Helmut}, title = {A haptic sensor-actuator-system based on ultrasound elastography and electrorheological fluids for virtual reality applications in medicine}, series = {CARS 2003 : computer assisted radiology and surgery ; proceedings of the 17th International Congress and Exhibition London, June 25 - 28, 2003}, booktitle = {CARS 2003 : computer assisted radiology and surgery ; proceedings of the 17th International Congress and Exhibition London, June 25 - 28, 2003}, publisher = {Elsevier}, address = {Amsterdam}, pages = {1354}, abstract = {Mechanical properties of biological tissue represent important diagnostic information and are of histological relevance (hard lesions, "nodes" in organs: tumors; calcifications in vessels: arteriosclerosis). The problem is, that such information is usually obtained by digital palpation only, which is limited with respect to sensitivity. It requires intuitive assessment and does not allow quantitative documentation. A suitable sensor is required for quantitative detection of mechanical tissue properties. On the other hand, there is also some need for a realistic mechanical display of those tissue properties. Suitable actuator arrays with high spatial resolution and real-time capabilities are required operating in a haptic sensor actuator system with different applications. The sensor system uses real time ultrasonic elastography whereas the tactile actuator is based on electrorheological fluids. Due to their small size the actuator array elements have to be manufactured by micro-mechanical production methods. In order to supply the actuator elements with individual high voltages a sophisticated switching and control concept have been designed. This haptic system has the potential of inducing real time substantial forces, using a compact lightweight mechanism which can be applied to numerous areas including intraoperative navigation, telemedicine, teaching, space and telecommunication.}, language = {en} } @article{KhaledErmertBruhnsetal., author = {Khaled, W. and Ermert, Helmut and Bruhns, Otto T. and Reichling, S. and B{\"o}se, Holger and Baumann, Michael and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and Klein, Dagmar and Freimuth, Herbert}, title = {Haptic sensor-actuator-system based on ultrasound elastography and electrorheological fluids for virtual reality applications in medicine}, series = {Studies in health technology and informatics, Medicine Meets Virtual Reality (MMVR)}, volume = {11}, journal = {Studies in health technology and informatics, Medicine Meets Virtual Reality (MMVR)}, number = {94}, publisher = {IOS Press}, pages = {144 -- 150}, abstract = {Mechanical properties of biological tissue represent important diagnostic information and are of histological relevance (hard lesions, "nodes" in organs: tumors; calcifications in vessels: arteriosclerosis). The problem is, that such information is usually obtained by digital palpation only, which is limited with respect to sensitivity. It requires intuitive assessment and does not allow quantitative documentation. A suitable sensor is required for quantitative detection of mechanical tissue properties. On the other hand, there is also some need for a realistic mechanical display of those tissue properties. Suitable actuator arrays with high spatial resolution and real-time capabilities are required operating in a haptic sensor actuator system with different applications. The sensor system uses real time ultrasonic elastography whereas the tactile actuator is based on electrorheological fluids. Due to their small size the actuator array elements have to be manufactured by micro-mechanical production methods. In order to supply the actuator elements with individual high voltages a sophisticated switching and control concept have been designed. This haptic system has the potential of inducing real time substantial forces, using a compact lightweight mechanism which can be applied to numerous areas including intraoperative navigation, telemedicine, teaching, space and telecommunication.}, language = {de} } @inproceedings{KhaledReichlingBruhnsetal., author = {Khaled, W. and Reichling, S. and Bruhns, Otto T. and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Baumann, Michael and B{\"o}se, Holger and Klein, Dagmar and Freimuth, Herbert and Tunayar, A. and Lorenz, A. and Pessavento, A. and Ermert, Helmut}, title = {Palpation imaging using a haptic system for virtual reality applications in medicine}, series = {Perspective in image-guided surgery : proceedings of the Scientific Workshop on Medical Robotics, Navigation, and Visualization : RheinAhrCampus Remagen, Germany, 11-12 March}, booktitle = {Perspective in image-guided surgery : proceedings of the Scientific Workshop on Medical Robotics, Navigation, and Visualization : RheinAhrCampus Remagen, Germany, 11-12 March}, publisher = {World Scientific Publ.}, address = {Singapore}, pages = {407 -- 414}, language = {en} } @inproceedings{KhaledReichlingBruhnsetal., author = {Khaled, W. and Reichling, S. and Bruhns, Otto T. and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Baumann, Michael and B{\"o}se, Holger and Klein, Dagmar and Freimuth, Herbert and Tunayar, A. and Lorenz, A. and Pessavento, A. and Ermert, Helmut}, title = {Palpation Imaging using a Haptic System for Virtual Reality Applications in Medicine}, series = {Proceedings of the 12th Annual Medicine Meets Virtual Reality Conference: - Building a Better You: The Next Tools for Medical Education, Diagnosis, and Care. - Medicine Meets Virtual Reality (MMVR) - Newport Beach (California, USA). 2004}, booktitle = {Proceedings of the 12th Annual Medicine Meets Virtual Reality Conference: - Building a Better You: The Next Tools for Medical Education, Diagnosis, and Care. - Medicine Meets Virtual Reality (MMVR) - Newport Beach (California, USA). 2004}, language = {en} } @inproceedings{KhaledBruhnsReichlingetal., author = {Khaled, W. and Bruhns, Otto T. and Reichling, S. and B{\"o}se, Holger and Baumann, Michael and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and Freimuth, Herbert and Tunayar, A. and Ermert, Helmut}, title = {A New Haptic Sensor Actuator System for Virtual Reality Applications in Medicine}, series = {Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003: 6th International Conference, Montr{\´e}al, Canada, November 15-18, 2003, Proceedings}, booktitle = {Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003: 6th International Conference, Montr{\´e}al, Canada, November 15-18, 2003, Proceedings}, publisher = {Springer}, isbn = {978-3540204626}, pages = {132 -- 140}, language = {en} } @article{KhaledBruhnsReichlingetal., author = {Khaled, W. and Bruhns, Otto T. and Reichling, S. and B{\"o}se, Holger and Baumann, Michael and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and Klein, Dagmar and Freimuth, Herbert and Ermert, Helmut}, title = {A haptic system for virtual reality applications based on ultrasound elastography and electrorheological fluids}, series = {Acoustical Imaging}, journal = {Acoustical Imaging}, number = {27}, publisher = {Kluver Academic}, address = {Dordrecht \& New York}, doi = {10.1007/978-1-4020-2402-3_85}, pages = {667 -- 675}, language = {en} } @inproceedings{KhaledReichlingBruhnsetal., author = {Khaled, W. and Reichling, S. and Bruhns, Otto T. and Ermert, Helmut and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Baumann, Michael and B{\"o}se, Holger and Freimuth, Herbert and Tunayar, A.}, title = {Palpation imaging using a haptic sensor actuator system for medical applications}, series = {Actuator 2004 : 9th International Conference on New Actuators \& 3rd International Exhibition on Smart Actuators and Drive Systems, 14-16 June 2004, Bremen, Germany}, booktitle = {Actuator 2004 : 9th International Conference on New Actuators \& 3rd International Exhibition on Smart Actuators and Drive Systems, 14-16 June 2004, Bremen, Germany}, publisher = {HVG Hanseatische Veranstaltungs-GmbH}, address = {Bremen}, pages = {379 -- 382}, language = {en} } @article{KleinFreimuthMonkmanetal., author = {Klein, Dagmar and Freimuth, Herbert and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and Meier, Alexander and B{\"o}se, Holger and Baumann, Michael and Ermert, Helmut and Bruhns, Otto T.}, title = {Electrorheological Tactile Elements}, series = {Mechatronics}, volume = {15}, journal = {Mechatronics}, number = {7}, publisher = {Pergamon}, address = {Oxford}, doi = {10.1016/j.mechatronics.2004.05.007}, pages = {883 -- 897}, abstract = {The use of ultrasound systems for medical examination and diagnosis is nothing new. The extension of ultrasound techniques for real time elastographic analysis purposes represents a more recent development. Nevertheless, as they stand all such techniques rely on the interpretation of two-dimensional visual data displayed on a video screen. In reality however, a medical doctor will make as much use of exploratory touch as he or she does vision, making the simultaneous portrayal of both video and tactile information most desirable [B{\"o}se H, Monkman GJ, Freimuth H, Ermert H. Haptisches Sensor-Aktor-System uaf der grundlage der Echtzeitelastographie sowie von elktro- und magnetorheologischen Materialien "HASASEM" [3]. BMBF Antrag 01 IR A14D, Oktober 2000]. This paper discusses the preliminary tests and basic design parameters for single tactels using electrorheological fluids. The final aim is to produce a prototype three-dimensional tactile display comprising electrically switchable micro-machined cells whose mechanical moduli are governed by phase changes experienced by electrorheological fluids. This will be integrated with the latest elastographic ultrasonic sensor systems in order to present the human fingers with controllable surfaces capable of emulating biological tissue, muscle and bone.}, language = {en} } @article{KleinRensinkFreimuthetal., author = {Klein, Dagmar and Rensink, D. and Freimuth, Herbert and Monkman, Gareth J. and Egersd{\"o}rfer, Stefan and B{\"o}se, Holger and Baumann, Michael}, title = {Modelling the Response of a Tactile Array using an Electrorheological Fluids}, series = {Journal of Physics D: Applied Physics}, volume = {37}, journal = {Journal of Physics D: Applied Physics}, number = {5}, publisher = {IOP Publ.}, address = {Bristol}, issn = {1361-6463}, doi = {10.1088/0022-3727/37/5/023}, pages = {794 -- 803}, abstract = {This paper reports the first step in the development of a tactile array suitable for the presentation of haptic information in virtual reality. The system is based on the electric field dependence of the viscosity of electrorheological fluids. The simulation, as well as the experimental realization of single tactels is described. The mathematical approach is based on the Eckart model (Eckart W 2000 Continuum Mech. Thermodyn. 12 341-62) and its validity is demonstrated by comparing the resulting yield stress with the experimental results from Wunderlich (2000 Dissertation Universit{\"a}t Erlangen-N{\"u}rnberg). Two different tactel designs are realized and the experimental results are compared with numerical simulation. The design of modification B is shown to be applicable for the realization of an actuator array with high spatial resolution.}, language = {en} } @inproceedings{LegrandBoeseErmertetal., author = {Legrand, Virginie and B{\"o}se, Holger and Ermert, Helmut and Freimuth, Herbert and Baumann, Michael and Egersd{\"o}rfer, Stefan and Meier, Alexander and Dragoi, Daniel}, title = {Technologien f{\"u}r haptische Systeme in der Informations{\"u}bertragung}, series = {IAFW Tagung - Lengenfeld, Mai 2003}, booktitle = {IAFW Tagung - Lengenfeld, Mai 2003}, language = {de} }