@article{WoehlMaierGehmertetal., author = {W{\"o}hl, Rebecca and Maier, Johannes and Gehmert, Sebastian and Palm, Christoph and Riebschl{\"a}ger, Birgit and Nerlich, Michael and Huber, Michaela}, title = {3D Analysis of Osteosyntheses Material using semi-automated CT Segmentation}, series = {BMC Musculoskeletal Disorders}, volume = {19}, journal = {BMC Musculoskeletal Disorders}, publisher = {Springer Nature}, doi = {10.1186/s12891-018-1975-0}, pages = {1 -- 8}, abstract = {Backround Scaphoidectomy and midcarpal fusion can be performed using traditional fixation methods like K-wires, staples, screws or different dorsal (non)locking arthrodesis systems. The aim of this study is to test the Aptus four corner locking plate and to compare the clinical findings to the data revealed by CT scans and semi-automated segmentation. Methods: This is a retrospective review of eleven patients suffering from scapholunate advanced collapse (SLAC) or scaphoid non-union advanced collapse (SNAC) wrist, who received a four corner fusion between August 2011 and July 2014. The clinical evaluation consisted of measuring the range of motion (ROM), strength and pain on a visual analogue scale (VAS). Additionally, the Disabilities of the Arm, Shoulder and Hand (QuickDASH) and the Mayo Wrist Score were assessed. A computerized tomography (CT) of the wrist was obtained six weeks postoperatively. After semi-automated segmentation of the CT scans, the models were post processed and surveyed. Results During the six-month follow-up mean range of motion (ROM) of the operated wrist was 60°, consisting of 30° extension and 30° flexion. While pain levels decreased significantly, 54\% of grip strength and 89\% of pinch strength were preserved compared to the contralateral healthy wrist. Union could be detected in all CT scans of the wrist. While X-ray pictures obtained postoperatively revealed no pathology, two user related technical complications were found through the 3D analysis, which correlated to the clinical outcome. Conclusion Due to semi-automated segmentation and 3D analysis it has been proved that the plate design can keep up to the manufacturers' promises. Over all, this case series confirmed that the plate can compete with the coexisting techniques concerning clinical outcome, union and complication rate.}, subject = {Handchirurgie}, language = {en} } @article{KolevKirchgessnerHoubenetal., author = {Kolev, Kalin and Kirchgeßner, Norbert and Houben, Sebastian and Csisz{\´a}r, Agnes and Rubner, Wolfgang and Palm, Christoph and Eiben, Bj{\"o}rn and Merkel, Rudolf and Cremers, Daniel}, title = {A variational approach to vesicle membrane reconstruction from fluorescence imaging}, series = {Pattern Recognition}, volume = {44}, journal = {Pattern Recognition}, number = {12}, publisher = {Elsevier}, doi = {10.1016/j.patcog.2011.04.019}, pages = {2944 -- 2958}, abstract = {Biological applications like vesicle membrane analysis involve the precise segmentation of 3D structures in noisy volumetric data, obtained by techniques like magnetic resonance imaging (MRI) or laser scanning microscopy (LSM). Dealing with such data is a challenging task and requires robust and accurate segmentation methods. In this article, we propose a novel energy model for 3D segmentation fusing various cues like regional intensity subdivision, edge alignment and orientation information. The uniqueness of the approach consists in the definition of a new anisotropic regularizer, which accounts for the unbalanced slicing of the measured volume data, and the generalization of an efficient numerical scheme for solving the arising minimization problem, based on linearization and fixed-point iteration. We show how the proposed energy model can be optimized globally by making use of recent continuous convex relaxation techniques. The accuracy and robustness of the presented approach are demonstrated by evaluating it on multiple real data sets and comparing it to alternative segmentation methods based on level sets. Although the proposed model is designed with focus on the particular application at hand, it is general enough to be applied to a variety of different segmentation tasks.}, subject = {Dreidimensionale Bildverarbeitung}, language = {en} }