@misc{HirmerDanilovGiglbergeretal., author = {Hirmer, Marion and Danilov, Sergey N. and Giglberger, Stephan and Putzger, J{\"u}rgen and Niklas, Andreas and J{\"a}ger, Andreas and Hiller, Karl-Anton and Schmalz, Gottfried and Redlich, Britta and Monkman, Gareth J. and Ganichev, Sergey D.}, title = {Spectroscopic Study of Human Teeth and Blood from Visible to Terahertz Frequencies for Clinical Diagnosis of Dental Pulp Vitality}, series = {PACS, November 11, 2011}, journal = {PACS, November 11, 2011}, abstract = {Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated. The measurements carried out over a wide spectral range, from visible light down to terahertz radiation. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality.}, language = {en} } @inproceedings{MayerForsterRabindranathetal., author = {Mayer, Matthias and Forster, Eva and Rabindranath, Raman and Bentz, Alexander and B{\"o}se, Holger and Shamonin (Chamonine), Mikhail and Monkman, Gareth J.}, title = {Highly compliant Magneto-Active Polymers (MAPs)}, series = {Actuator'11, Bremen, May 2011}, booktitle = {Actuator'11, Bremen, May 2011}, language = {en} } @incollection{SchrimerPutzMonkman, author = {Schrimer, M and Putz, Christoph and Monkman, Gareth J.}, title = {Boron-Silicone-Oxide Polymers}, series = {Boron: advances in research and applications}, booktitle = {Boron: advances in research and applications}, editor = {McConnell, Lynn}, publisher = {Nova Science Publishers}, address = {New York, NY}, isbn = {9781685072315}, doi = {10.52305/AFKU5564}, pages = {117 -- 179}, language = {en} } @article{ZimmermannChavezVegaBeckeretal., author = {Zimmermann, Klaus and Chavez Vega, Jhohan Harvey and Becker, Tatiana I. and Witte, Hartmut and Schilling, Cornelius and K{\"o}hring, Sebastian and B{\"o}hm, Valter and Monkman, Gareth J. and Prem, Nina and Sindersberger, Dirk and Lutz, I. I. and Merker, Lukas}, title = {An approach to a form-adaptive compliant gripper element based on magneto-sensitive elastomers with a bioinspired sensorized surface}, series = {Problems of Mechanics}, volume = {75}, journal = {Problems of Mechanics}, number = {2}, publisher = {Georgian Technical University}, address = {Tbilisi}, issn = {1512-0740}, pages = {23 -- 38}, language = {en} } @misc{ChavezVegaBoehmYinetal., author = {Chavez Vega, Jhohan Harvey and B{\"o}hm, Valter and Yin, J. and Becker, Tatiana I. and K{\"o}hring, Sebastian and Monkman, Gareth J. and Odenbach, Stefan and Zimmermann, Klaus}, title = {Field induced plasticity of magneto-sensitive elastomers for gripping technology applications}, series = {6th Colloquium of SPP 1681, Benediktbeuern, 26. - 28.09.2018 : Book of Abstracts}, journal = {6th Colloquium of SPP 1681, Benediktbeuern, 26. - 28.09.2018 : Book of Abstracts}, pages = {16 -- 17}, language = {en} } @inproceedings{DrexlerHirmerDanilovetal., author = {Drexler, C. and Hirmer, Marion and Danilov, Sergey N. and Giglberger, Stephan and Putzger, J{\"u}rgen and Niklas, Andreas and J{\"a}ger, Andreas and Hiller, Karl-Anton and L{\"o}ffler, S. and Schmalz, Gottfried and Redlich, Britta and Schulz, Irene and Monkman, Gareth J. and Ganichev, Sergey D.}, title = {Infrared spectroscopy for clinical diagnosis of dental pulp vitality}, series = {37th International Conference on Infrared, Millimetre, and Terahertz Waves (IRMMW-THz 37), 23-28 September 2012 , Wollongong, Australia}, booktitle = {37th International Conference on Infrared, Millimetre, and Terahertz Waves (IRMMW-THz 37), 23-28 September 2012 , Wollongong, Australia}, publisher = {IEEE}, address = {Piscataway, NJ}, doi = {10.1109/IRMMW-THz.2012.6380091}, abstract = {Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated over a wide spectral range, from visible to terahertz (THz) light. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality.}, language = {en} } @inproceedings{ForsterRabindranathMayeretal., author = {Forster, Eva and Rabindranath, Raman and Mayer, Matthias and Bentz, Alexander and B{\"o}se, Holger and Shamonin (Chamonine), Mikhail and Monkman, Gareth J.}, title = {Characterization of ultra soft Magneto-Active Polymers (MAPs)}, series = {Conference proceedings / INDUCTICA 2011, Berlin, Germany, 24 - 26 May}, booktitle = {Conference proceedings / INDUCTICA 2011, Berlin, Germany, 24 - 26 May}, language = {en} } @inproceedings{NerlichMonkmanFuechtmeieretal., author = {Nerlich, Michael and Monkman, Gareth J. and F{\"u}chtmeier, Bernd and Egersd{\"o}rfer, Stefan}, title = {Development of a Robotic Navigation and Fracture Fixation System}, series = {1. Jahrestagung der Deutschen Gesellschaft f{\"u}r Computer- und Roboterassistierte Chirurgie (CURAC), Leipzig, 2002}, booktitle = {1. Jahrestagung der Deutschen Gesellschaft f{\"u}r Computer- und Roboterassistierte Chirurgie (CURAC), Leipzig, 2002}, language = {en} } @misc{BroserFalterŁawrowskietal., author = {Broser, Christian and Falter, Thomas and Ławrowski, Robert Damian and Altenbuchner, Amelie and V{\"o}gele, Daniel and Koss, Claus and Schlamp, Matthias and Dunnweber, Jan and Steffens, Oliver and Heckner, Markus and Jaritz, Sabine and Schiegl, Thomas and Corsten, Sabine and Lauer, Norina and Guertler, Katherine and Koenig, Eric and Haug, Sonja and Huber, Dominik and Birkenmaier, Clemens and Krenkel, Lars and Wagner, Thomas and Justus, Xenia and Saßmannshausen, Sean Patrick and Kleine, Nadine and Weber, Karsten and Braun, Carina N. and Giacoppo, Giuliano and Heinrich, Michael and Just, Tobias and Schreck, Thomas and Schnabl, Andreas and Gilmore, Amador T{\´e}ran and Roeslin, Samuel and Schmid, Sandra and Wellnitz, Felix and Malz, Sebastian and Maurial, Andreas and Hauser, Florian and Mottok, J{\"u}rgen and Klettke, Meike and Scherzinger, Stefanie and St{\"o}rl, Uta and Heckner, Markus and Bazo, Alexander and Wolff, Christian and Kopper, Andreas and Westner, Markus and Pongratz, Christian and Ehrlich, Ingo and Briem, Ulrich and Hederer, Sebastian and Wagner, Marcus and Schillinger, Moritz and G{\"o}rlach, Julien and Hierl, Stefan and Siegl, Marco and Langer, Christoph and Hausladen, Matthias and Schreiner, Rupert and Haslbeck, Matthias and Kreuzer, Reinhard and Br{\"u}ckl, Oliver and Dawoud, Belal and Rabl, Hans-Peter and Gamisch, Bernd and Schmidt, Ottfried and Heberl, Michael and G{\"a}nsbauer, Bianca and Bick, Werner and Ellermeier, Andreas and Monkman, Gareth J. and Prem, Nina and Sindersberger, Dirk and Tschurtschenthaler, Karl and Aurbach, Maximilian and Dendorfer, Sebastian and Betz, Michael A. and Szecsey, Tamara and Mauerer, Wolfgang and Murr, Florian}, title = {Forschung 2018}, editor = {Baier, Wolfgang}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg}, isbn = {978-3-9818209-5-9}, doi = {10.35096/othr/pub-1382}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-13826}, pages = {98}, subject = {Forschung}, language = {de} } @techreport{RabindranathBoeseProbstetal., author = {Rabindranath, Raman and B{\"o}se, Holger and Probst, J{\"o}rn and Schlunck, G{\"u}nther and Mayer, Matthias and Forster, Eva and Bentz, Alexander and Shamonin (Chamonine), Mikhail and Monkman, Gareth J.}, title = {EAP mit magnetisch steuerbarer Elastizit{\"a}t zur Interaktion mit Bindegewebszellen MagElan}, address = {Regensburg}, organization = {Hochschule f{\"u}r Angewandte Wissenschaften Regensburg / Fachbereich Elektro- und Informationstechnik}, pages = {37}, language = {de} } @article{DillingerWeberMayeretal., author = {Dillinger, Andrea Elisabeth and Weber, Gregor R. and Mayer, Matthias and Schneider, Magdalena and G{\"o}ppner, Corinna and Ohlmann, Andreas and Shamonin (Chamonine), Mikhail and Monkman, Gareth J. and Fuchshofer, Rudolf and Keller, Kate and Lozano, Diana C. and Clark, Abbot}, title = {CCN2/CTGF-A Modulator of the Optic Nerve Head Astrocyte}, series = {Frontiers in cell and developmental biology (Front Cell Dev Biol.)}, volume = {10}, journal = {Frontiers in cell and developmental biology (Front Cell Dev Biol.)}, publisher = {frontiers}, doi = {10.3389/fcell.2022.864433}, pages = {864433}, abstract = {In primary open-angle glaucoma (POAG), a neurodegenerative disease of the optic nerve (ON) and leading cause of blindness, the optic nerve head (ONH) undergoes marked structural extracellular matrix (ECM) changes, which contribute to its permanent deformation and to degeneration of ON axons. The remodeling process of the ECM causes changes in the biomechanical properties of the ONH and the peripapillary sclera, which is accompanied by an increased reactivity of the resident astrocytes. The molecular factors involved in the remodeling process belong to the Transforming growth factor (TGF)-β superfamily, especially TGF-β2. In previous publications we showed that TGF-β2 induced ECM alterations are mediated by Cellular Communication Network Factor (CCN)2/Connective Tissue Growth Factor (CTGF) and recently we showed that CCN2/CTGF is expressed by astrocytes of the ON under normal conditions. In this study we wanted to get a better understanding of the function of CCN2/CTGF under normal and pathologic conditions. To this end, we analyzed the glial lamina and peripapillary sclera of CCN2/CTGF overexpressing mice and studied the effect of CCN2/CTGF and increasing substratum stiffness on murine ON astrocytes in vitro. We observed enhanced astrocyte reactivity in the ONH, increased ECM protein synthesis in the peripapillary sclera and increased Ccn2/Ctgf expression in the ONH during the pathologic development in situ. CCN2/CTGF treatment of primary murine ON astrocytes induced a higher migration rate, and increase of ECM proteins including fibronectin, elastin and collagen type III. Furthermore, the astrocytes responded to stiffer substratum with increased glial fibrillary acidic protein, vimentin, actin and CCN2/CTGF synthesis. Finally, we observed the reinforced appearance of CCN2/CTGF in the lamina cribrosa of glaucomatous patients. We conclude that reactive changes in ONH astrocytes, induced by the altered biomechanical characteristics of the region, give rise to a self-amplifying process that includes increased TGF-β2/CCN2/CTGF signaling and leads to the synthesis of ECM molecules and cytoskeleton proteins, a process that in turn augments the stiffness at the ONH. Such a scenario may finally result in a vicious circle in the pathogenesis of POAG. The transgenic CTGF-overexpressing mouse model might be an optimal model to study the chronic pathological POAG changes in the ONH.}, language = {en} }