@inproceedings{BrunnerRoederKuceraetal., author = {Brunner, Stefan and R{\"o}der, J{\"u}rgen and Kucera, Markus and Waas, Thomas}, title = {Automotive E/E-architecture enhancements by usage of ethernet TSN}, series = {13th Workshop on Intelligent Solutions in Embedded Systems (WISES), 12-13 June 2017, Hamburg, Germany}, booktitle = {13th Workshop on Intelligent Solutions in Embedded Systems (WISES), 12-13 June 2017, Hamburg, Germany}, publisher = {IEEE}, doi = {10.1109/WISES.2017.7986925}, pages = {9 -- 13}, abstract = {A huge upheaval emerges from the transition to autonomous vehicles in the domain of road vehicles, ongoing with a change in the vehicle architecture. Many sensors and Electronic Control Units are added to the current vehicle architecture and further safety requirements like reliability become even more necessary. In this paper we present a potential evolution of the Electrical/Electronic-Architecture, including a Zone Architecture, to enable future functionality. We reveal the impact on the communication network concerning these architectures and present a potential communication technology to facilitate such architectures.}, subject = {Kraftfahrzeug}, language = {en} } @inproceedings{BuettnerKuceraWaas, author = {B{\"u}ttner, Johannes and Kucera, Markus and Waas, Thomas}, title = {Opening up New Fail-Safe Layers in Distributed Vehicle Computer Systems}, series = {Proceedings of the 8th International Joint Conference on Pervasive and Embedded Computing (PECCS 2018) 2018, Porto, Portugal}, booktitle = {Proceedings of the 8th International Joint Conference on Pervasive and Embedded Computing (PECCS 2018) 2018, Porto, Portugal}, abstract = {The automotive industry currently faces several challenges, including a growing complexity in system architecture. At the same time, the task load as well as the needs for performance increase. To address this problem, the A3Fa research project evaluates scalable distributed concepts for future vehicle system architectures. These can be seen as comparable to cluster-computing systems, which are applied in high-performance or high-availability use-cases. Methods used in such scenarios will also be important features in future vehicle architectures such as horizontal application scalability, application load balancing and reallocation, as well as functionality upgrades triggered by the user. This paper focuses on concepts and methods for the reliability of applications and hardware in future in-vehicle distributed system architectures. It is argued that future automotive computing systems will evolve towards enterprise IT systems similar to today's data centers. Furthermore, it is stated these vehicle systems can benefit greatly from IT systems. In particular, the safety against failure of functions and hardware in such systems is discussed. For this purpose, various of such mechanisms used in information technology are investigated. A layer-based classification is proposed, representing the different fail-safe levels.}, subject = {Kraftfahrzeug}, language = {en} } @article{AmannHaug, author = {Amann, Karina and Haug, Sonja}, title = {Wie k{\"o}nnen demokratische Prozesse organisiert werden?}, series = {TRIOLOG}, journal = {TRIOLOG}, number = {1}, organization = {Hochschulverbund TRIO}, pages = {34 -- 35}, subject = {Demokratie}, language = {de} } @incollection{HaugWolf, author = {Haug, Sonja and Wolf, Michael}, title = {J{\"u}dische Zuwanderung nach Deutschland}, series = {Neue Zuwanderergruppen in Deutschland}, booktitle = {Neue Zuwanderergruppen in Deutschland}, editor = {Haug, Sonja and Swiaczny, Frank}, publisher = {Bundesinstitut f{\"u}r Bev{\"o}lkerungsforschung}, address = {Wiesbaden}, pages = {65 -- 82}, language = {de} } @incollection{Haug, author = {Haug, Sonja}, title = {Storia d'Immigrazione e Tendenze All' Integrazione di Emigrati Italiani in Germania}, series = {Andare, Restare, Tornare. Cinquant' Anni di Emigrazione Italiana in Germania}, booktitle = {Andare, Restare, Tornare. Cinquant' Anni di Emigrazione Italiana in Germania}, editor = {Carchedi, Francesco and Pugliese, Enrico}, publisher = {Cosmo Iannone Editore}, address = {Isernia}, pages = {45 -- 56}, language = {it} } @incollection{Haug, author = {Haug, Sonja}, title = {Soziales Kapital als Ressource im Kontext von Migration und Integration}, series = {Soziale Netzwerke und soziale Ungleichheit. Zur Rolle von Sozialkapital in modernen Gesellschaften}, booktitle = {Soziale Netzwerke und soziale Ungleichheit. Zur Rolle von Sozialkapital in modernen Gesellschaften}, editor = {Diewald, Martin and L{\"u}dicke, J{\"o}rg}, publisher = {Verlag f{\"u}r Sozialwissenschaften}, address = {Wiesbaden}, doi = {10.1007/978-3-531-90458-0_4}, pages = {85 -- 111}, language = {de} } @incollection{HaugGerlitz, author = {Haug, Sonja and Gerlitz, Jean-Yves}, title = {Messkonzepte sozialen Kapitals}, series = {Jahrbuch {\"O}kologische {\"O}konomik - Soziale Nachhaltigkeit}, booktitle = {Jahrbuch {\"O}kologische {\"O}konomik - Soziale Nachhaltigkeit}, editor = {Meyerhoff, J{\"u}rgen and Schwarze, Reimund}, publisher = {Metropolis Verlag}, address = {Marburg}, pages = {189 -- 218}, language = {de} } @incollection{Haug, author = {Haug, Sonja}, title = {Raubkopierer als moderne Freibeuter}, series = {Rational Choice: Theoretische Analysen und empirische Resultate. Festschrift f{\"u}r Karl-Dieter Opp zum 70. Geburtstag}, booktitle = {Rational Choice: Theoretische Analysen und empirische Resultate. Festschrift f{\"u}r Karl-Dieter Opp zum 70. Geburtstag}, editor = {Diekmann, Andreas and Eichner, Klaus and Schmidt, Peter and Voss, Thomas}, publisher = {Verlag f{\"u}r Sozialwissenschaften}, address = {Wiesbaden}, doi = {10.1007/978-3-531-90866-3_8}, pages = {119 -- 141}, language = {de} } @misc{Haug, author = {Haug, Sonja}, title = {Internationale Wanderungsbewegungen und individuelle Verl{\"a}ufe von Migration}, series = {Die Natur der Gesellschaft : Verhandlungen des 33. Kongresses der Deutschen Gesellschaft f{\"u}r Soziologie in Kassel}, journal = {Die Natur der Gesellschaft : Verhandlungen des 33. Kongresses der Deutschen Gesellschaft f{\"u}r Soziologie in Kassel}, editor = {Rehberg, Karl-Siegbert}, publisher = {Campus}, address = {Wiesbaden}, language = {de} } @article{WesselyHausleiterMichaelisetal., author = {Wessely, Rainer and Hausleiter, J{\"o}rg and Michaelis, Cornelia and Jaschke, Birgit and Vogeser, Michael and Milz, Stefan and Behnisch, Boris and Schratzenstaller, Thomas and Renke-Gluszko, Magdalena and St{\"o}ver, Michael and Wintermantel, Erich and Kastrati, Adnan and Sch{\"o}mig, Albert}, title = {Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating}, series = {Arteriosclerosis, Thrombosis, and Vascular Biology}, volume = {25}, journal = {Arteriosclerosis, Thrombosis, and Vascular Biology}, number = {4}, issn = {1524-4636}, doi = {10.1161/01.ATV.0000157579.52566.ee}, pages = {748 -- 753}, abstract = {Objective The risk of in-stent restenosis can be considerably reduced by stents eluting cytostatic compounds. We created a novel drug-eluting stent system that includes several new features in the rapidly evolving field of stent-based drug delivery. Methods and Results The aim of the present study was the preclinical evaluation of a stent-coating system permitting individual, on-site coating of stents with a unique microporous surface allowing for individualizable, dose-adjustable, and multiple coatings with identical or various compounds, designated ISAR (individualizable drug-eluting stent system to abrogate restenosis). Stents were coated with 0.75\% rapamycin solution, and high-performance liquid chromatography (HPLC)-based determination of drug release profile indicated drug release for >21 days. Rapamycin-eluting microporous (REMP) stents implanted in porcine coronary arteries were safe. To determine the efficacy of REMP stents, this novel drug-eluting stent platform was compared with the standard sirolimus-eluting stent. At 30 days, in-stent neointima formation in porcine coronary arteries was similar in both groups, yielding a significant decrease of neointimal area and injury-dependent neointimal thickness compared with bare-metal stents. Conclusion The ISAR drug-eluting stent platform as a novel concept for stent coating allows for a safe, effective, on-site stent coating process, thus justifying further clinical evaluation to decrease in-stent restenosis in humans. In-stent neointima formation can be successfully attenuated by drug-eluting stents. We introduce a novel conceptual approach for stent-coating that allows for dose-adjustable, on-site stent coating process if desired with multiple compounds. Microporous stents coated with rapamycin proved safe and effective for the limitation of neointima formation in a porcine coronary stent model.}, language = {en} } @article{HausleiterKastratiWesselyetal., author = {Hausleiter, J{\"o}rg and Kastrati, Adnan and Wessely, Rainer and Dibra, Alban and Mehilli, Julinda and Schratzenstaller, Thomas and Graf, Isolde and Renke-Gluszko, Magdalena and Behnisch, Boris and Dirschinger, Josef and Wintermantel, Erich and Sch{\"o}mig, Albert}, title = {Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating}, series = {European Heart Journal - Clinical research}, volume = {26}, journal = {European Heart Journal - Clinical research}, number = {15}, doi = {10.1093/eurheartj/ehi405}, pages = {1475 -- 1481}, abstract = {Aims Drug-eluting stents (DES) represent a major advance in interventional cardiology. Along with the success shown, current DES also present limitations related to the presence of polymer-coating, fixed drug, and dose used. With the ISAR (Individualized Drug-Eluting Stent System to Abrogate Restenosis) project, a DES system has been developed that permits individualized choice of the drug and dose to use for the given patient. The objective of this prospective dose finding study was to assess the feasibility, safety, and efficacy of a polymer-free on-site stent coating with increasing rapamycin doses. Methods and results In this dose finding study, 602 patients were sequentially enrolled in four groups: microporous bare metal stent (BMS), DES stents coated with a 0.5, 1.0, and 2.0\% rapamycin solution. The angiographic in-segment restenosis rate at follow-up angiography was the primary study endpoint. In-segment restenosis was significantly reduced from 25.9\% with BMS to 18.9, 17.2, and 14.7\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.024). Similarly, the need for target lesion revascularization at 1 year follow-up was reduced from 21.5\% with BMS to 16.4, 12.6, and 8.8\% with 0.5, 1.0, and 2.0\% rapamycin-eluting stents, respectively (P=0.006). Conclusion The placement of polymer-free stents coated on-site with rapamycin is feasible and safe. Furthermore, a dose-dependent efficacy in restenosis prevention is achievable with this new DES concept.}, language = {en} } @article{GeithNothdurfterHeimletal., author = {Geith, Markus A. and Nothdurfter, Laurenz and Heiml, Manuel and Agrafiotis, Emmanouil and Gruber, Markus and Sommer, Gerhard and Schratzenstaller, Thomas and Holzapfel, Gerhard A.}, title = {Quantifying stent-induced damage in coronary arteries by investigating mechanical and structural alterations}, series = {Acta Biomaterialia}, volume = {116}, journal = {Acta Biomaterialia}, number = {October}, publisher = {Elsevier}, doi = {10.1016/j.actbio.2020.08.016}, pages = {285 -- 301}, abstract = {Vascular damage develops with diverging severity during and after percutaneous coronary intervention with stent placement and is the prevailing stimulus for in-stent restenosis. Previous work has failed to link mechanical data obtained in a realistic in vivo or in vitro environment with data collected during imaging processes. We investigated whether specimens of porcine right coronary arteries soften when indented with a stent strut shaped structure, and if the softening results from damage mechanisms inside the fibrillar collagen structure. To simulate the multiaxial loading scenario of a stented coronary artery, we developed the testing device 'LAESIO' that can measure differences in the stress-stretch behavior of the arterial wall before and after the indentation of a strut-like stamp. The testing protocol was optimized according to preliminary experiments, more specifically equilibrium and relaxation tests. After chemical fixation of the specimens and subsequent tissue clearing, we performed three-dimensional surface and second-harmonic generation scans on the deformed specimens. We analyzed and correlated the mechanical response with structural parameters of high-affected tissue located next to the stamp indentation and low-affected tissue beyond the injured area. The results reveal that damage mechanisms, like tissue compression as well as softening, fiber dispersion, and the lesion extent, are direction-dependent, and the severity of them is linked to the strut orientation, indentation pressure, and position. The findings highlight the need for further investigations by applying the proposed methods to human coronary arteries. Additional data and insights might help to incorporate the observed damage mechanisms into material models for finite element analyses to perform more accurate simulations of stent-implantations.}, language = {en} } @article{GeithEckmannHaspingeretal., author = {Geith, Markus A. and Eckmann, Jakob D. and Haspinger, Daniel Ch. and Agrafiotis, Emmanouil and Maier, Dominik and Szabo, Patrick and Sommer, Gerhard and Schratzenstaller, Thomas and Holzapfel, Gerhard A.}, title = {Experimental and mathematical characterization of coronary polyamide-12 balloon catheter membranes}, series = {PLoS One}, volume = {15}, journal = {PLoS One}, number = {6}, publisher = {PLOS}, doi = {10.1371/journal.pone.0234340}, pages = {1 -- 22}, abstract = {The experimental quantification and modeling of the multiaxial mechanical response of polymer membranes of coronary balloon catheters have not yet been carried out. Due to the lack of insights, it is not shown whether isotropic material models can describe the material response of balloon catheter membranes expanded with nominal or higher, supra-nominal pressures. Therefore, for the first time, specimens of commercial polyamide-12 balloon catheters membranes were investigated during uniaxial and biaxial loading scenarios. Furthermore, the influence of kinematic effects on the material response was observed by comparing results from quasi-static and dynamic biaxial extension tests. Novel clamping techniques are described, which allow to test even tiny specimens taken from the balloon membranes. The results of this study reveal the semi-compliant, nonlinear, and viscoelastic character of polyamide-12 balloon catheter membranes. Above nominal pressure, the membranes show a pronounced anisotropic mechanical behavior with a stiffer response in the circumferential direction. The anisotropic feature intensifies with an increasing strain-rate. A modified polynomial model was applied to represent the realistic mechanical response of the balloon catheter membranes during dynamic biaxial extension tests. This study also includes a compact set of constitutive model parameters for the use of the proposed model in future finite element analyses to perform more accurate simulations of expanding balloon catheters.}, language = {en} } @article{PrantlEigenbergerKleinetal., author = {Prantl, Lukas and Eigenberger, Andreas and Klein, Silvan and Limm, Katharina and Oefner, Peter J. and Schratzenstaller, Thomas and Felthaus, Oliver}, title = {Shear Force Processing of Lipoaspirates for Stem Cell Enrichment Does Not Affect Secretome of Human Cells Detected by Mass Spectrometry In Vitro}, series = {Plastic and Reconstructive Surgery}, volume = {146}, journal = {Plastic and Reconstructive Surgery}, number = {6}, publisher = {American Society of Plastic Surgeons}, doi = {10.1097/PRS.0000000000007343}, pages = {749e -- 758e}, abstract = {Background: Lipofilling is one of the most often performed surgical procedures in plastic and reconstructive surgery. Lipoaspirates provide a ready source of stem cells and secreted factors that contribute to neoangiogenesis and fat graft survival. However, the regulations about the enrichment of these beneficial cells and factors are ambiguous. In this study, the authors tested whether a combination of centrifugation and homogenization allowed the enrichment of viable stem cells in lipoaspirates through the selective removal of tumescent solution, blood, and released lipids without significantly affecting the cell secretome. Methods: Human lipoaspirate was harvested from six different patients using water jet-assisted liposuction. Lipoaspirate was homogenized by first centrifugation (3584 rpm for 2 minutes), shear strain (10 times intersyringe processing), and second centrifugation (3584 rpm for 2 minutes). Stem cell enrichment was shown by cell counting after stem cell isolation. Lipoaspirate from different processing steps (unprocessed, after first centrifugation, after homogenization, after second centrifugation) was incubated in serum-free cell culture medium for mass spectrometric analysis of secreted proteins. Results: Lipoaspirate homogenization leads to a significant 2.6 ± 1.75-fold enrichment attributable to volume reduction without reducing the viability of the stem cells. Protein composition of the secretome did not change significantly after tissue homogenization. Considering the enrichment effects, there were no significant differences in the protein concentration of the 83 proteins found in all processing steps. Conclusions: Stem cells can be enriched mechanically without significantly affecting the composition of secreted proteins. Shear-assisted enrichment of lipoaspirate constitutes no substantial manipulation of the cells' secretome.}, language = {en} } @article{MaierDesernoHandelsetal., author = {Maier, Andreas and Deserno, Thomas M. and Handels, Heinz and Maier-Hein, Klaus H. and Palm, Christoph and Tolxdorff, Thomas}, title = {IJCARS: BVM 2021 special issue}, series = {International Journal of Computer Assisted Radiology and Surgery}, volume = {16}, journal = {International Journal of Computer Assisted Radiology and Surgery}, publisher = {Springer}, doi = {10.1007/s11548-021-02534-7}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-21666}, pages = {2067 -- 2068}, abstract = {The German workshop on medical image computing (BVM) has been held in different locations in Germany for more than 20 years. In terms of content, BVM focused on the computer-aided analysis of medical image data with a wide range of applications, e.g. in the area of imaging, diagnostics, operation planning, computer-aided intervention and visualization. During this time, there have been remarkable methodological developments and upheavals, on which the BVM community has worked intensively. The area of machine learning should be emphasized, which has led to significant improvements, especially for tasks of classification and segmentation, but increasingly also in image formation and registration. As a result, work in connection with deep learning now dominates the BVM. These developments have also contributed to the establishment of medical image processing at the interface between computer science and medicine as one of the key technologies for the digitization of the health system. In addition to the presentation of current research results, a central aspect of the BVM is primarily the promotion of young scientists from the diverse BVM community, covering not only Germany but also Austria, Switzerland, The Netherland and other European neighbors. The conference serves primarily doctoral students and postdocs, but also students with excellent bachelor and master theses as a platform to present their work, to enter into professional discourse with the community, and to establish networks with specialist colleagues. Despite the many conferences and congresses that are also relevant for medical image processing, the BVM has therefore lost none of its importance and attractiveness and has retained its permanent place in the annual conference rhythm. Building on this foundation, there are some innovations and changes this year. The BVM 2021 was organized for the first time at the Ostbayerische Technische Hochschule Regensburg (OTH Regensburg, a technical university of applied sciences). After Aachen, Berlin, Erlangen, Freiburg, Hamburg, Heidelberg, Leipzig, L{\"u}beck, and Munich, Regensburg is not just a new venue. OTH Regensburg is the first representative of the universities of applied sciences (HAW) to organize the conference, which differs to universities, university hospitals, or research centers like Fraunhofer or Helmholtz. This also considers the further development of the research landscape in Germany, where HAWs increasingly contribute to applied research in addition to their focus on teaching. This development is also reflected in the contributions submitted to the BVM in recent years. At BVM 2021, which was held in a virtual format for the first time due to the Corona pandemic, an attractive and high-quality program was offered. Fortunately, the number of submissions increased significantly. Out of 97 submissions, 26 presentations, 51 posters and 5 software demonstrations were accepted via an anonymized reviewing process with three reviews each. The three best works have been awarded BVM prizes, selected by a separate committee. Based on these high-quality submissions, we are able to present another special issue in the International Journal of Computer Assisted Radiology and Surgery (IJCARS). Out of the 97 submissions, the ones with the highest scores have been invited to submit an extended version of their paper to be presented in IJCARS. As a result, we are now able to present this special issue with seven excellent articles. Many submissions focus on machine learning in a medical context.}, subject = {Bildgebendes Verfahren}, language = {en} } @article{Haug, author = {Haug, Sonja}, title = {Herkunft, Glaubensrichtung, Bildung, Partizipation}, series = {Politik und Kultur - Zeitung des Deutschen Kulturrates. Dossier Islam}, journal = {Politik und Kultur - Zeitung des Deutschen Kulturrates. Dossier Islam}, number = {Januar - Februar}, pages = {5}, abstract = {In der Diskussion um muslimische Zuwanderer wird selten auf die Vielschichtigkeit des muslimischen Lebens in Deutschland eingegangen. Ein Blick auf die verf{\"u}gbaren Daten kann hier aufschlussreich sein und dient zudem der Versachlichung. Im Rahmen einer bundesweit repr{\"a}sentativen Studie des Bundesamtes f{\"u}r Migration und Fl{\"u}chtlinge wurden im Jahr 2008 im Auftrag der Deutschen Islam Konferenz 6.000 Haushalte aus f{\"u}nfzig muslimisch gepr{\"a}gten Herkunftsl{\"a}ndern befragt.}, language = {de} } @article{Haug, author = {Haug, Sonja}, title = {Junge T{\"u}rken haben Ehrgeiz}, series = {Mittelbayrische Zeitung}, journal = {Mittelbayrische Zeitung}, language = {de} } @article{Haug, author = {Haug, Sonja}, title = {Hohe Zufriedenheit mit der Kultur in Regensburg}, series = {Bei uns. Stadt Regensburg}, journal = {Bei uns. Stadt Regensburg}, number = {173 (November)}, pages = {8 -- 10}, abstract = {Wie soll das k{\"u}nftige kulturelle Angebot in Regensburg aussehen? Dieser zentralen Frage geht der Kulturentwicklungsplan nach, an dem seit Anfang 2010 gearbeitet wird. Neben Arbeitsgruppen mit Kulturschaffenden setzt das Kulturreferat dabei insbesondere auf die Meinung der Regensburgerinnen und Regensburger. Inzwi- schen liegt das Ergebnis einer B{\"u}rgerbefragung vor, das Sonja Haug, Professorin f{\"u}r empirische Sozialforschung an der Regens- burger Hochschule f{\"u}r angewandte Wissenschaften, gemeinsam mit einem Team ausgewertet hat.}, subject = {Kulturelle Entwicklung}, language = {de} } @article{KheiroddinSchoeberlAlthammeretal., author = {Kheiroddin, Parastoo and Sch{\"o}berl, Patricia and Althammer, Michael and Cibali, Ezgi and W{\"u}rfel, Thea and Wein, Hannah and Kulawik, Birgit and Buntrock-D{\"o}pke, Heike and Weigl, Eva and Gran, Silvia and Gr{\"u}ndl, Magdalena and Langguth, Jana and Lampl, Benedikt and Judex, Guido and Niggel, Jakob and Pagel, Philipp and Schratzenstaller, Thomas and Schneider-Brachert, Wulf and Gastiger, Susanne and Bodenschatz, Mona and Konrad, Maike and Levchuk, Artem and Roth, Cornelius and Sch{\"o}ner, David and Schneebauer, Florian and Rohrmanstorfer, Ren{\´e} and Burkovski, Andreas and Ambrosch, Andreas and Wagner, Thomas and Kabesch, Michael}, title = {Results of WICOVIR Gargle Pool PCR Testing in German Schools Based on the First 100,000 Tests}, series = {Frontiers in Pediatrics}, volume = {9}, journal = {Frontiers in Pediatrics}, editor = {Buonsenso, Danilo}, publisher = {frontiers}, issn = {2296-2360}, doi = {10.3389/fped.2021.721518}, abstract = {Background: Opening schools and keeping children safe from SARS-CoV-2 infections at the same time is urgently needed to protect children from direct and indirect consequences of the COVID-19 pandemic. To achieve this goal, a safe, efficient, and cost-effective SARS-CoV-2 testing system for schools in addition to standard hygiene measures is necessary. Methods: We implemented the screening WICOVIR concept for schools in the southeast of Germany, which is based on gargling at home, pooling of samples in schools, and assessment of SARS-CoV-2 by pool rRT-PCR, performed decentralized in numerous participating laboratories. Depooling was performed if pools were positive, and results were transmitted with software specifically developed for the project within a day. Here, we report the results after the first 13 weeks in the project. Findings: We developed and implemented the proof-of-concept test system within a pilot phase of 7 weeks based on almost 17,000 participants. After 6 weeks in the main phase of the project, we performed >100,000 tests in total, analyzed in 7,896 pools, identifying 19 cases in >100 participating schools. On average, positive children showed an individual CT value of 31 when identified in the pools. Up to 30 samples were pooled (mean 13) in general, based on school classes and attached school staff. All three participating laboratories detected positive samples reliably with their previously established rRT-PCR standard protocols. When self-administered antigen tests were performed concomitantly in positive cases, only one of these eight tests was positive, and when antigen tests performed after positive pool rRT-PCR results were already known were included, 3 out of 11 truly positive tests were also identified by antigen testing. After 3 weeks of repetitive WICOVIR testing twice weekly, the detection rate of positive children in that cohort decreased significantly from 0.042 to 0.012 (p = 0.008). Interpretation: Repeated gargle pool rRT-PCR testing can be implemented quickly in schools. It is an effective, valid, and well-received test system for schools, superior to antigen tests in sensitivity, acceptance, and costs.}, subject = {Covid-19}, language = {en} } @article{WiesentSchultheissLullaetal., author = {Wiesent, Lisa and Schultheiß, Ulrich and Lulla, Philipp and Noster, Ulf and Schratzenstaller, Thomas and Schmid, Christof and Nonn, Aida and Spear, Ashley}, title = {Computational analysis of the effects of geometric irregularities and post-processing steps on the mechanical behavior of additively manufactured 316L stainless steel stents}, series = {PLoS ONE}, volume = {15}, journal = {PLoS ONE}, number = {12}, publisher = {PLOS}, doi = {10.1371/journal.pone.0244463}, pages = {1 -- 30}, abstract = {Advances in additive manufacturing enable the production of tailored lattice structures and thus, in principle, coronary stents. This study investigates the effects of process-related irregularities, heat and surface treatment on the morphology, mechanical response, and expansion behavior of 316L stainless steel stents produced by laser powder bed fusion and provides a methodological approach for their numerical evaluation. A combined experimental and computational framework is used, based on both actual and computationally reconstructed laser powder bed fused stents. Process-related morphological deviations between the as-designed and actual laser powder bed fused stents were observed, resulting in a diameter increase by a factor of 2-2.6 for the stents without surface treatment and 1.3-2 for the electropolished stent compared to the as-designed stent. Thus, due to the increased geometrically induced stiffness, the laser powder bed fused stents in the as-built (7.11 ± 0.63 N) or the heat treated condition (5.87 ± 0.49 N) showed increased radial forces when compressed between two plates. After electropolishing, the heat treated stents exhibited radial forces (2.38 ± 0.23 N) comparable to conventional metallic stents. The laser powder bed fused stents were further affected by the size effect, resulting in a reduced yield strength by 41\% in the as-built and by 59\% in the heat treated condition compared to the bulk material obtained from tensile tests. The presented numerical approach was successful in predicting the macroscopic mechanical response of the stents under compression. During deformation, increased stiffness and local stress concentration were observed within the laser powder bed fused stents. Subsequent numerical expansion analysis of the derived stent models within a previously verified numerical model of stent expansion showed that electropolished and heat treated laser powder bed fused stents can exhibit comparable expansion behavior to conventional stents. The findings from this work motivate future experimental/numerical studies to quantify threshold values of critical geometric irregularities, which could be used to establish design guidelines for laser powder bed fused stents/lattice structures.}, subject = {Koronarendoprothese}, language = {en} } @inproceedings{DuennweberSarkarPuthiyadathetal., author = {D{\"u}nnweber, Jan and Sarkar, Amitrajit and Puthiyadath, Vimal Kumar and Barde, Omkar}, title = {A Tale of Four Cities - Improving Bus and Waste Collection Schedules in Practical Smart City Applications}, series = {Computer Information Systems and Industrial Management}, booktitle = {Computer Information Systems and Industrial Management}, editor = {Saeed, Khalid and Dvorsk{\´y}, Jiř{\´i}}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-84340-3}, doi = {10.1007/978-3-030-84340-3_30}, pages = {369 -- 380}, abstract = {Computer-based Improvements of waste collection and public transport procedures are often a part of smart city initiatives. When we envision an ideal bus network, it will primarily connect the most crowded bus stops. Similarly, an ideal waste collection vehicle will arrive at every container exactly at the time when it is fully loaded. Beyond doubt, this will reduce traffic and support environmentally friendly intentions like waste separation, as it will make more containers manageable. A difficulty of putting that vision into practice is that vehicles cannot always be where they are needed. Knowing the best time for arriving at a position is not insufficient for finding the optimal route. Therefore, we compare four different approaches to optimized routing: Regensburg, Christchurch, Malaysia, and Bangalore. Our analysis shows that the best schedules result from adapting field-tested routes frequently based on sensor measurements and route optimizing computations.}, language = {en} } @inproceedings{StadlerSarkarDuennweber, author = {Stadler, Timo and Sarkar, Amitrajit and D{\"u}nnweber, Jan}, title = {Bus Demand Forecasting for Rural Areas Using XGBoost and Random Forest Algorithm}, series = {CISIM2021: 20th International Conference on Computer Information Systems and Industrial Management Applications, September 24-26 2021, Ełk, Poland}, booktitle = {CISIM2021: 20th International Conference on Computer Information Systems and Industrial Management Applications, September 24-26 2021, Ełk, Poland}, editor = {Saeed, Khalid and Dvorsk{\´y}, Jiř{\´i}}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-84340-3}, doi = {10.1007/978-3-030-84340-3_36}, pages = {442 -- 453}, abstract = {In recent years, mobility solutions have experienced a significant upswing. Consequently, it has increased the importance of forecasting the number of passengers and determining the associated demand for vehicles. We analyze all bus routes in a rural area in contrast to other work that predicts just a single bus route. Some differences in bus routes in rural areas compared to cities are highlighted and substantiated by a case study data using Roding, a town in the rural district of Cham in northern Bavaria, as an example. Data collected and we selected a random forest model that lets us determine the passenger demand, bus line effectiveness, or general user behavior. The prediction accuracy of the selected model is currently 87\%. The collected data helps to build new mobility-as-a-service solutions, such as on-call buses or dynamic route optimizations, as we show with our simulation.}, subject = {{\"O}ffentlicher Personennahverkehr}, language = {en} } @inproceedings{BurgerSarkarKirschetal., author = {Burger, David and Sarkar, Amitrajit and Kirsch, Konstantin and D{\"u}nnweber, Jan}, title = {Combining Fill-Level Sensing with Route Optimization for a More Efficient Waste Collection}, series = {ECDG 2018 - European Conference on Digital Government, 2018, Santiago De Compostela, Spain}, booktitle = {ECDG 2018 - European Conference on Digital Government, 2018, Santiago De Compostela, Spain}, editor = {Bouzas Lorenzo, Ram{\´o}n}, isbn = {9781912764037}, pages = {24 -- 31}, abstract = {We tackle the problem that collecting all the waste of modern cities within the scheduled time spans becomes increasingly challenging, while the waste collection team is not supplemented accordingly in many places, e.g. by more staff or vehicles. Separating waste has become natural for urban populations, as recycling is ecologically necessary. However, the separation also leads to a continuously increasing number of containers which are logistically unmanageable without computer-aided collection scheduling. Regensburg recently introduced a new program for the collection of biological waste, which extends the private collection of such waste by a few hundred public biological waste containers. Computer support was pretty basic so far, i.e. the collection times were recorded and the routes were sporadically rescheduled manually in an Excel sheet. We show that much shorter waste collection routes can be found automatically using a dynamic version of the classic Ant Colony Optimization (ACO) algorithm for shortening the collection routes. Moreover, we sketch an loT (lnternet-of-Things) approach to "lntelligent Waste Containers" which we equip with ultrasonic sensors monitoring the fill levels, which allows us to skip poorly used containers during the collection and reposition them on demand. By means of a computer simulation with online visualization, we illustrate that our optimized and dynamically adapted collection routes lead to significant time savings. Indeed, more than twice the number of currently used containers can be collected within the same time. We also report about the first experiments that we conducted with real sensors. The presented work is the result of a cooperation between four contributing parties: 1) Technical University of Regensburg (OTH); 2) Ara Institute of Canterbury; 3) Regensburg's Governmental Department of Waste Management; and 4) an industry partner (kpit.com). We compare the outcome of our project with related work and we sketch some future perspectives and ideas for transforming Regensburg into an even more automatized, environmentally friendly "smart city".}, language = {en} } @inproceedings{WinterDuennweber, author = {Winter, Christoph and D{\"u}nnweber, Jan}, title = {Model-Driven Development of GPU Applications}, series = {Parallel Computing: On the Road to Exascale}, booktitle = {Parallel Computing: On the Road to Exascale}, publisher = {IOS Press}, address = {Amsterdam, Netherlands}, isbn = {978-1-61499-621-7}, doi = {10.3233/978-1-61499-621-7-227}, pages = {227 -- 236}, abstract = {Programming GPUs with low-level libraries like CUDA and OpenCL is a tedious and error-prone task. Fortunately, algorithmic skeletons can shield developers from the complexity of parallel programming by encapsulating common parallel computing patterns. However, this simplification typically constrains programmers to write their applications using the GPU library employed by the skeleton implementation. In this work, we combine skeletal programming with modeldriven software development (MDSD) to increase the freedom of choice regarding the employed GPU library instead of leaving all technical decisions to the skeleton implementation. We present a code-generator that transforms models comprising skeletons, their input data and input functions to parallel C++ code while taking care of data-offset calculations. The generator has been tested using different GPU and multi-GPU communication libraries such as Thrust and CUDA-MPI. We demonstrate our novel approach to GPU programming with two example applications: affinity propagation and n-body simulation.}, language = {en} } @article{BaumgartenDuennweberKirsch, author = {Baumgarten, Bodo and D{\"u}nnweber, Jan and Kirsch, C.}, title = {Report Big Data - Strukturierung von Tourismusdaten mit Hadoop}, series = {iX - Magazin f{\"u}r professionelle Informationstechnik}, journal = {iX - Magazin f{\"u}r professionelle Informationstechnik}, number = {06}, publisher = {heise}, address = {Hannover}, issn = {0935-9680}, pages = {97 -- 101}, abstract = {Ein weitverbreitetes, unstrukturiertes Datenformat stellt Reiseveranstalter inzwischen vor technische und logistische Probleme. Abhilfe k{\"o}nnte ein neues Format in Zusammenarbeit mit Cloud-Techniken schaffen.}, language = {de} } @inproceedings{DuennweberMihaylovGlettleretal., author = {D{\"u}nnweber, Jan and Mihaylov, Valentin and Glettler, Ren{\´e} and Maiborn, Volker and Wolff, Holger}, title = {Use of HPC-Techniques for Large-Scale Data Migration}, series = {Workshop on High-Performance Computing Applied to Finance, 2011, Ischia, Italy}, booktitle = {Workshop on High-Performance Computing Applied to Finance, 2011, Ischia, Italy}, publisher = {Springer}, address = {Berlin, Heidelberg}, isbn = {978-3-642-21877-4}, doi = {10.1007/978-3-642-29737-3_45}, abstract = {Any re-design of a distributed legacy system requires a migration which involves numerous complex data replication and transformation steps. Migration procedures can become quite difficult and time-consuming, especially when the setup (i.e., the employed databases, encodings, formats etc.) of the legacy and the target system fundamentally differ, which is often the case with finance data, grown over decades. We report on experiences from a real-world project: the recent migration of a customer loyalty system from a COBOL-operated mainframe to a modern service-oriented architecture. In this context, we present our easy-to-adopt solution for running most replication steps in a high-performance manner: the QuickApply HPC-software which helps minimizing the replication time, and, thereby, the overall downtime of the migration. Business processes can be kept up and running most of the time, while pre-extracted data already pass a variety of platforms and representations toward the target system. We combine the advantages of traditional migration approaches: transformations, which require the interruption of business processes are performed with static data only, they can be made undone in case of a failure and terminate quickly, due to the use of parallel processing.}, language = {en} } @article{DuennweberKirsch, author = {D{\"u}nnweber, Jan and Kirsch, C.}, title = {Report Datenmigration}, series = {iX - Magazin f{\"u}r professionelle Informationstechnik}, journal = {iX - Magazin f{\"u}r professionelle Informationstechnik}, number = {11}, publisher = {Heise}, address = {Hannover}, issn = {0935-9680}, pages = {95 -- 100}, abstract = {Mehrere Terabyte Daten aus einem auf dem Mainframe laufenden COBOL-Programm auf eine SOA-Architektur unter Linux zu migrieren, stellt besondere Anforderungen an die Werkzeuge und Entwickler. Geschickte Kombination vorhandener Tools und effizienter Strategien vermeiden Stillstandszeiten und beschleunigen den Datentransfer.}, language = {de} } @book{DuennweberGorlatch, author = {D{\"u}nnweber, Jan and Gorlatch, Sergei}, title = {Higher-Order Components for Grid Programming}, publisher = {Springer}, address = {Berlin, Heidelberg}, isbn = {978-3-642-00841-2}, doi = {10.1007/978-3-642-00841-2}, abstract = {A major challenge in grid computing remains the application software development for this new kind of infrastructure. Grid application programmers have to take into account several complicated aspects: distribution of data and computations, parallel computations on different sites and processors, heterogeneity of the involved computers, load balancing, etc. Grid programmers thus demand novel programming methodologies that abstract over such technical details while preserving the beneficial features of modern grid middleware. For this purpose, the authors introduce Higher-Order Components (HOCs). HOCs implement generic parallel/distributed processing patterns, together with the required middleware support, and they are offered to users via a high-level service interface. Users only have to provide the application-specific pieces of their programs as parameters, while low-level implementation details, such as the transfer of data across the grid, are handled by the HOCs. HOCs were developed within the CoreGRID European Network of Excellence and have become an optional extension of the popular Globus middleware. The book provides the reader with hands-on experience, describing a broad collection of example applications from various fields of science and engineering, including biology, physics, etc. The Java code for these examples is provided online, complementing the book. The expected application performance is studied and reported for extensive performance experiments on different testbeds, including grids with worldwide distribution. The book is targeted at graduate students, advanced professionals, and researchers in both academia and industry. Readers can raise their level of knowledge about methodologies for programming contemporary parallel and distributed systems, and, furthermore, they can gain practical experience in using distributed software. Practical examples show how the complementary online material can easily be adopted in various new projects.}, language = {en} } @article{MuellerIdenDuennweberGorlatchetal., author = {M{\"u}ller-Iden, Jens and D{\"u}nnweber, Jan and Gorlatch, Sergei and Alt, Martin and Fujita, Hamido and Funyu, Yutaka}, title = {Clayworks: Toward user-oriented software for collaborative modeling}, series = {Knowledge-Based Systems}, volume = {22}, journal = {Knowledge-Based Systems}, number = {3}, publisher = {Elsevier}, address = {Oxford, UK}, doi = {10.1016/j.knosys.2008.12.001}, pages = {209 -- 215}, abstract = {We consider the development of software systems that integrate collaborative real-time modeling and distributed computing. Our main goal is user-orientation: we need a collaborative workspace for geographically dispersed users with a seamless access of every user to high-performance servers. This paper presents a particular prototype, Clayworks, that allows modeling of virtual clay objects and running computation-intensive deformation simulations for objects crashing into each other. In order to integrate heterogeneous computational resources, we adopt modern Grid middleware and provide the users with an intuitive graphical interface. Simulations are parallelized using a higher-order component (HOC) which abstracts over the web service resource framework (WSRF) used to interconnect our worksuite to the computation server. Clayworks is a representative of a large class of demanding systems which combine collaborative, user-oriented modeling with performance-critical computations, e.g., crash-tests or simulations of biological population evolution.}, language = {en} } @inproceedings{DumitrescuEpemaDuennweber, author = {Dumitrescu, C{\^a}t{\^a}lin L. and Epema, Dick H. J. and D{\"u}nnweber, Jan}, title = {User-Transparent Scheduling for Software Components on the Grid}, series = {Achievements in European Research on Grid Systems}, booktitle = {Achievements in European Research on Grid Systems}, editor = {Gorlatch, Sergei and Bubak, Marian and Priol, Thierry}, publisher = {Springer}, address = {Boston, MA}, isbn = {978-0-387-72811-7}, doi = {10.1007/978-0-387-72812-4_4}, pages = {41 -- 53}, abstract = {Grid applications are increasingly being developed as workflows using well-structured, reusable components. We argue that components with well-defined semantics facilitate an efficient scheduling on the Grid. We have previously developed a user-transparent scheduling approach for Higher-Order Components (HOCs) - parallel implementations of typical programming patterns, accessible and customizable via Web services. Our approach combines three scheduling techniques: using cost functions for reducing communication overhead, reusability of schedules for similar workflows, and the aggregated submission of jobs. We analyze the user-transparent scheduling from four perspectives, namely: the easiness of integration within already existing Grid scheduling systems, the gains for individual users, the resource provider advantages, and the robustness with respect to execution failures. We perform our evaluation using the KOALA Grid scheduler extended to support our user-transparent scheduling, which we run on the DAS-2 system combining over 200 nodes at five sites in the Netherlands. The experimental results show an increase in throughput by more than 100\%, a descreasing of the response time by 50\%, and a failure reduction by 45\% for the considered scenarios}, language = {en} } @incollection{DuennweberDumitrescuRaicuetal., author = {D{\"u}nnweber, Jan and Dumitrescu, Cǎtǎlin L. and Raicu, Ioan and Foster, Ian}, title = {Simplifying Grid Application Programming Using Web-Enabled Code Transfer Tools}, series = {Towards Next Generation Grids}, booktitle = {Towards Next Generation Grids}, editor = {Priol, Thierry and Vanneschi, Marco}, publisher = {Springer}, address = {Rennes, France}, isbn = {978-0-387-72497-3}, doi = {10.1007/978-0-387-72498-0_21}, pages = {225 -- 235}, abstract = {This paper deals with one of the fundamental properties of grid computing - transferring code between grid nodes and executing it remotely on heterogeneous hosts. Contemporary middleware relies for this purpose on Web Services, which makes application programs complicated and low-level and requires much additional expertise from programmers. We compare two mechanisms for grid application programming with regard to their handling of code transfer - the de-facto standard WS-GRAM in Globus and the higher-level approach based on HOCs (Higher-Order Components). We study the advantages and problems of each approach using a real-world application case study - the sequent alignment problem from bioinformatics. Our experiments show the trade-off between reduced development costs and software complexity when HOCs are used and the higher performance of the applications on the grid when using WS-GRAM.}, language = {en} } @incollection{DuennweberTomasoniGorlatchetal., author = {D{\"u}nnweber, Jan and Tomasoni, Johannes and Gorlatch, Sergei and Claßen, Michael and Claßen, Philipp and Lengauer, Christian}, title = {A Grid Component with Embedded Loop Parallelization}, series = {Grid Computing}, booktitle = {Grid Computing}, editor = {Gorlatch, Sergei and Fragopoulou, Paraskevi and Priol, Thierry}, publisher = {Springer}, address = {Berlin}, isbn = {978-0-387-09456-4}, doi = {10.1007/978-0-387-09457-1_22}, pages = {261 -- 273}, abstract = {This work integrates two distinct research areas of parallel and distributed computing, (1) automatic loop parallelization, and (2) component-based Grid programming. The latter includes technologies developed within CoreGRID for simplifying Grid programming: the Grid ComponentModel (GCM) and Higher- Order Components (HOCs). Components support developing applications on the Grid without taking all the technical details of the particular platform type into account (network communication, heterogeneity, etc.). The GCMenables a hierarchical composition of programpieces and HOCs enable the reuse of component code in the development of new applications by specifying application-specific operations in a program via code parameters. When a programmer is provided, e. g., with a compute farm HOC, only the independent worker tasks must be described. But, once an application exhibits data or control dependences, the trivial farm is no longer sufficient. Here, the power of loop parallelization tools, like LooPo, comes into play: by embedding LooPo into a HOC, we show that these two technologies in combination facilitate the automatic transformation of a sequential loop nest with complex dependences (supplied by the user as a HOC parameter) into an ordered task graph, which can be processed on the Grid in parallel. This technique can significantly simplify GCM-based systems which combine multiple HOCs and other components. We use an equation system solver based on the successive overrelaxation method (SOR) as our motivating application example and for performance experiments.}, language = {en} } @incollection{DuennweberLuedekingGorlatch, author = {D{\"u}nnweber, Jan and L{\"u}deking, Philipp and Gorlatch, Sergei}, title = {A Higher-Order Component for Efficient Genome Processing on the Grid}, series = {Making Grids Work}, booktitle = {Making Grids Work}, editor = {Danelutto, Marco and Fragopoulou, Paraskevi and Getov, Vladimir}, publisher = {Springer}, address = {Boston, MA}, isbn = {978-0-387-78447-2}, doi = {10.1007/978-0-387-78448-9_28}, pages = {351 -- 362}, abstract = {Computational grids combine computers in the Internet for distributed data processing and are an attractive platform for the data-intensive applications of bioinformatics. We present an extensible genome processing software for the grid and evaluate its performance. Our software was able to discover previously unknown circular permutations (CP) in the ProDom database containing more than 70MB of protein data. A specific feature of our software is its design as a component: the Alignment HOC, a Higher-Order Component that makes use of the latest Globus toolkit as grid middleware. Besides genome data, the Alignment HOC accepts plugin code for processing this data as its input, and contains all the required configuration to run the component on top of Globus, thus, freeing the non-grid-expert user from dealing with grid middleware. Instead of writing data distribution procedures and configuring the middleware appropriately for every new algorithm, Alignment HOC users reuse the existing component and only write application-specific plugins. To maintain plugins persistently in a reusable manner, we built a web-accessible plugin database with a comfortable administration GUI. The flexible component-based implementation makes it easy to study CPs in other databases (e.g. UniProt/Swiss-Prot) or to use an alignment algorithm different than the standard Needleman-Wunsch. For the efficient distribution of workload, we developed a library of group communication operations for HOCs.}, language = {en} } @incollection{DuennweberAldinucciGorlatchetal., author = {D{\"u}nnweber, Jan and Aldinucci, Marco and Gorlatch, Sergei and Campa, Sonia and Danelutto, Marco}, title = {Adaptable Parallel Components for Grid Programming}, series = {Integrated Research in GRID Computing}, booktitle = {Integrated Research in GRID Computing}, editor = {Gorlatch, Sergei and Danelutto, Marco}, publisher = {Springer Verlag}, address = {Boston, MA}, isbn = {978-0-387-47656-8}, doi = {10.1007/978-0-387-47658-2_4}, pages = {43 -- 57}, abstract = {We suggest that parallel software components used for grid computing should be adaptable to application-specific requirements, instead of developing new components from scratch for each particular application. As an example, we take a parallel farm component which is "embarrassingly parallel", i. e., free of dependencies, and adapt it to the wavefront processing pattern with dependencies that impact its behavior. We describe our approach in the context of Higher-Order Components (HOCs), with the Java-based system Lithium as our implementation framework. The adaptation process relies on HOCs' mobile code parameters that are shipped over the network of the grid. We describe our implementation of the proposed component adaptation method and report first experimental results for a particular grid application — the alignment of DNA sequence pairs, a popular, time-critical problem in computational molecular biology.}, language = {en} } @inproceedings{MuellerAltDuennweberetal., author = {M{\"u}ller, Jens and Alt, Martin and D{\"u}nnweber, Jan and Gorlatch, Sergei}, title = {Clayworks}, series = {IEEE International Conference on e-Science and Grid Computing (e-Science'06), 2nd, 4-6 Dec 2006, Amsterdam, Netherlands}, booktitle = {IEEE International Conference on e-Science and Grid Computing (e-Science'06), 2nd, 4-6 Dec 2006, Amsterdam, Netherlands}, isbn = {0-7695-2734-5}, doi = {10.1109/E-SCIENCE.2006.261188}, abstract = {Clayworks is a software system which integrates collaborative real-time modeling and distributed computing. It addresses the challenge of developing a collaborative workspace with a seamless access to high-performance servers. Clayworks allows modeling of virtual clay objects and running computation-intensive deformation simulations for objects crashing into each other. To integrate heterogeneous computational resources, we adopted modern Grid middleware and provided the users with an intuitive graphical interface. We parallelized the computation of simulations using a Higher-Order Component (HOC) which abstracts over the Globus Web service resource framework (WSRF) used to interconnect our worksuite to the computation server. Clayworks is a representative of a large class of demanding systems which combine collaborative modeling with performance-critical computations, e.g., crash-tests or simulations for biological population evolution.}, language = {en} } @incollection{DuennweberParlavatzasGorlatchetal., author = {D{\"u}nnweber, Jan and Parlavatzas, Nikos and Gorlatch, Sergei and Baude, Francoise and Legrand, Virginie}, title = {Automatic Creation of Web Services for Grid Components}, series = {Integrated Research in GRID Computing}, booktitle = {Integrated Research in GRID Computing}, editor = {Gorlatch, Sergei and Danelutto, Marco}, publisher = {Springer}, address = {Sophia Antipolis, France}, isbn = {978-0-387-47656-8}, doi = {10.1007/978-0-387-47658-2_3}, pages = {31 -- 42}, abstract = {While high-level software components simplify the programming of grid applications and Web services increase their interoperability, developing such components and configuring the interconnecting services is a demanding task. In this paper, we consider the combination of Higher-Order Components (HOCs) with the Fractal component model and the ProActive library. HOCs are parallel programming components, made accessible on the grid via Web services that use a special class loader enabling code mobility: executable code can be uploaded to a HOC, allowing one to customize the HOC. Fractal simplifies the composition of components and the ProActive library offers a generator for automatically creating Web services from components composed with Fractal, as long as all the parameters of these services have primitive types. Taking all the advantages of HOCs, ProActive and Fractal together, the obvious conclusion is that composing HOCs using Fractal and automatically exposing them as Web services on the grid via ProActive minimizes the required efforts for building complex grid systems. In this context, we solved the problem of exchanging code-carrying parameters in automatically generated Web services by integrating the HOC class loading mechanism into the ProActive library.}, language = {en} } @incollection{GorlatchDuennweber, author = {Gorlatch, Sergei and D{\"u}nnweber, Jan}, title = {From Grid Middleware to Grid Applications}, series = {Future Generation Grids}, booktitle = {Future Generation Grids}, editor = {Getov, Vladimir and Laforenza, Domenico and Reinefeld, Alexander}, publisher = {Springer Verlag}, address = {Berlin}, isbn = {978-0-387-27935-0}, doi = {10.1007/978-0-387-29445-2_13}, pages = {241 -- 261}, abstract = {This paper deals with the problem of application programming for grid systems that combine heterogeneous data and computational resources via the Internet. We argue that grid programming is still too complex because of the big gap between the currently used and anticipated grid middleware, (e.g., Globus or WSRF) and the application level. We suggest that this gap needs to be closed in future-generation grids and propose a novel approach to bridging the gap by using Higher-Order Components (HOCs) — recurring patterns of parallel behaviour that are provided to the user as program building blocks with pre-packaged implementation and middleware setup. The presentation is illustrated with a simple case study of computing fractal images. Our experiments demonstrate that HOCs can simplify grid application programming significantly, without serious performance loss.}, language = {en} } @incollection{AldinucciDuennweberDaneluttoetal., author = {Aldinucci, Marco and D{\"u}nnweber, Jan and Danelutto, Marco and Golatch, Sergei}, title = {Optimization techniques for skeletons on grids}, series = {Grid Computing: The New Frontier of High Performance Computing}, booktitle = {Grid Computing: The New Frontier of High Performance Computing}, editor = {Grandinetti, Lucio}, publisher = {Elsevier}, address = {Scotland}, isbn = {978-0-08-046146-5}, doi = {10.1016/S0927-5452(05)80014-0}, pages = {255 -- 273}, abstract = {Skeletons are common patterns of parallelism, such as farm and pipeline, that can be abstracted and offered to the application programmer as programming primitives. We describe the use and implementation of skeletons on emerging computational grids, with the skeleton system Lithium, based on Java and RMI, as our reference programming syttem. Our main contribution is the exploration of optimization techniques for implementing skeletons on grids based on an optimized, future-based RMI mechanism, which we integrate into the macro-dataflow evaluation mechanism of Lithium. We discuss three optimizations: 1) a lookahead mechanism that allows to process multiple tasks concurrently at each grid server and thereby increases the overall degree of parallelism, 2) a lazy taskbinding technique that reduces interactions between grid servers and the task dispatcher, and 3) dynamic improvements that optimize the collecting of results and the work-load balancing. We report experimental results that demonstrate the improvements due to our optimizations on various testbeds, including a heterogeneous grid-like environment.}, language = {en} } @inproceedings{DuennweberGorlatch, author = {D{\"u}nnweber, Jan and Gorlatch, Sergei}, title = {HOC-SA}, series = {IEEE International Conference on Services Computing (SCC 2004), 15-18 Sept. 2004, Shanghai, China}, booktitle = {IEEE International Conference on Services Computing (SCC 2004), 15-18 Sept. 2004, Shanghai, China}, isbn = {0-7695-2225-4}, doi = {10.1109/SCC.2004.1358017}, abstract = {The current efforts on programming grid applications often rely on service-oriented approaches like grid services. This work presents HOC-SA -a service architecture for higher-order components, which provides the programmer with reusable and composable patterns of parallelism and is interoperable with the latest Globus toolkit implementations. We describe our implementation of HOC-SA using OGSA-DAI, a framework for integrating grids with distributed databases. We present a simple example application and report first measurements on our grid testbed.}, language = {en} } @inproceedings{DuennweberGorlatchBenoitetal., author = {D{\"u}nnweber, Jan and Gorlatch, Sergei and Benoit, Anne and Cole, Murray}, title = {Integrating MPI-Skeletons with Web Services}, series = {ParCo'05 - International Conference on Parallel Computing, 2005, Malaga, Spain}, booktitle = {ParCo'05 - International Conference on Parallel Computing, 2005, Malaga, Spain}, pages = {787 -- 794}, abstract = {Interoperating components, implemented in multiple programming languages, are one of the key requirements of grid computing that operates over the borders of individual hardware and software platforms. Modern grid middleware like WSRF facilitates interoperability through service-orientation but it also increases software complexity. We show that Higher-Order Components (HOCs) provide a service-oriented programming abstraction over middleware technology. By offering the pipeline skeleton from the MPI-based eSkel library as a HOC, we show how machine-oriented technologies can be made available via Web Services on grids. We bind a Java-based Web application to the HOC to demonstrate its connectivity: user defined input can be transformed in a highly performant manner by running wavelet computations remotely on parallel machines.}, language = {en} } @book{BoerschSupanHunklerWeiss, author = {B{\"o}rsch-Supan, Axel and Hunkler, Christian and Weiss, Matthias}, title = {Big Data at Work}, address = {Regensburg}, organization = {Ostbayerische Technische Hochschule Regensburg / Fakult{\"a}t Betriebswirtschaft}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-21637}, publisher = {Ostbayerische Technische Hochschule Regensburg}, pages = {59}, abstract = {Does productivity decline with age? Does population aging harm economic growth? We exploit process-generated data from a large and typical service-sector company. We find no decline in average productivity in the age range of 20-60. This result is precisely measured. Our innovative identification strategy corrects for sample selection, endogeneity of age composition and age-cohort confounding. Our big data are essential to extract the signal from the noise that has marred many previous studies. While average productivity stays flat, we find variation according to task complexity. Productivity increases with age in teams with more demanding tasks and decreases in routine tasks.}, subject = {Arbeitsproduktivit{\"a}t}, language = {en} } @article{HaugSeebass, author = {Haug, Sonja and Seebass, Katharina}, title = {Zug{\"a}nge zur Gesellschaft er{\"o}ffnen}, series = {Blickpunkt Integration}, volume = {2009}, journal = {Blickpunkt Integration}, number = {3}, publisher = {Bundesamt f{\"u}r Migration und Fl{\"u}chtlinge}, pages = {11}, language = {de} } @article{Haug, author = {Haug, Sonja}, title = {Muslim, integriert und selbstst{\"a}ndig}, series = {Handelsblatt}, volume = {202}, journal = {Handelsblatt}, number = {7}, language = {de} } @article{HaugJoseph, author = {Haug, Sonja and Joseph, Saskia}, title = {Sie haben geantwortet.}, series = {Misericordia}, journal = {Misericordia}, number = {10}, pages = {20 -- 21}, language = {de} } @incollection{HaugSauer, author = {Haug, Sonja and Sauer, Lenore}, title = {Bestimmungsfaktoren internationaler Migration}, series = {Migration und ethnische Minderheiten}, booktitle = {Migration und ethnische Minderheiten}, number = {1}, publisher = {Informationszentrum Sozialwissenschaften}, address = {Bonn}, issn = {0938-6033}, pages = {7 -- 34}, abstract = {Der Bericht beinhaltet eine Zusammenfassung von Migrationstheorien aus {\"O}konomie und Sozialwissenschaften. Diese dienen der Erkl{\"a}rung von Wanderungsentscheidungen und Wanderungsbewegungen und stellen die Grundlage f{\"u}r die Vorhersage zuk{\"u}nftiger Wanderungsentwicklungen dar. Um vorhandene Studien {\"u}ber Migrationspotenziale zu beurteilen, ist es daher notwendig, Kenntnisse {\"u}ber theoretische Grundlagen zu haben. Insofern stellt diese Einf{\"u}hrung in die Migrationstheorie ein Werkzeug f{\"u}r den kritischen Umgang mit g{\"a}ngigen Prognosemodellen, Befragungsinstrumentenn und Sch{\"a}tzungen dar. Es werden mikro- und makrotheoretische Ans{\"a}tze sowie Meso-Ebenenans{\"a}tze beschrieben.}, language = {de} } @masterthesis{Gering, type = {Bachelor Thesis}, author = {Gering, Stefan}, title = {Thermische Detailsimulationen in der Bestandssanierung}, address = {Regensburg}, language = {de} } @article{Steffens, author = {Steffens, Oliver}, title = {Energetische Modernisierung und Restaurierung historisch wertvoller Stadtquartiere. Regenerative Energieversorgung als Schwerpunkt einer nachhaltigen Modernisierung historisch wertvoller Stadtquartiere (RENARHIS)}, series = {Zukunft bauen. Forschungsinitiative Zukunft Bau 2016}, journal = {Zukunft bauen. Forschungsinitiative Zukunft Bau 2016}, number = {5}, publisher = {Bundesministerium f{\"u}r Umwelt, Naturschutz, Bau und Reaktorsicherheit (BMUB)}, pages = {62 -- 65}, language = {de} } @article{MaierDesernoHandelsetal., author = {Maier, Andreas and Deserno, Thomas M. and Handels, Heinz and Maier-Hein, Klaus H. and Palm, Christoph and Tolxdorff, Thomas}, title = {Guest editorial of the IJCARS - BVM 2018 special issue}, series = {International Journal of Computer Assisted Radiology and Surgery}, volume = {14}, journal = {International Journal of Computer Assisted Radiology and Surgery}, publisher = {Springer}, doi = {10.1007/s11548-018-01902-0}, pages = {1 -- 2}, language = {en} } @misc{Urban, type = {Master Thesis}, author = {Urban, Johannes}, title = {Photoelektrisches Direktladen von Elektrofahrzeugen im Inselbetrieb}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-20285}, school = {Ostbayerische Technische Hochschule Regensburg}, pages = {118}, abstract = {Die Arbeit befasst sich mit der Ladung von Elektrofahrzeugen durch Solarenergie in einem Inselsystem. Diese Art der Ladung entlastet die Netze und hat einen sehr hohen Leistungswirkungsgrad. Es wurde ein Prototyp einer Direkt-ladestation gebaut, welche verschiedene Elektrofahrzeuge mit einem neuartigen Verfahren aufladen kann. Sie enth{\"a}lt einen optionalen Pufferakkumulator und einen Vollbr{\"u}cken-Gegentaktwandler f{\"u}r die Ladung bei schlechter Solarleistung. Ein Teil der Arbeit behandelt ausf{\"u}hrlich die Auslegung, die Komponenten und bisher undokumentiertes Verhalten von Gegentaktwandlern. Des Weiteren wird das Prinzip der Solardirekt-ladung und deren Umsetzung sowie die Umsetzung des Gesamtsystems beschrieben. Es folgt ein Kapitel zur Wirtschaftlichkeit der Solardirektladung mit Handlungsempfehlungen. Insgesamt l{\"a}sst sich schließen, dass Solardirektladung bei nutzungsorientierter Auslegung der Anlage und langer Laufzeit wirtschaftlich ist. This work addresses the charging of electric vehicles with solar power in an off-grid system. Charging this way reduces the stress on the grid and has a very high power efficiency. A prototype of a direct charging station was built which is able to charge several different electric vehicles in a novel way. It includes an optional buffer battery and a full bridge converter for being able to charge electric vehicles at times o flow solar power. One chapter explains in detail the design, the components and so far undocumented properties of full and half bridge converters. The principle and the implementation of direct solar charging and the implementation of the whole system is described. The last chapter covers the cost effectiveness of solar chargin gas well as recommendations. All in all it can be stated that solar direct charging is ecomomically advantageous if it is projected according to the user's demand.}, subject = {Fotovoltaik}, language = {de} } @article{Haug, author = {Haug, Sonja}, title = {Projektkooperation Stadt Regensburg und HS. R. Prof. Dr. Sonja Haug erarbeitet Integrationsbericht}, series = {Spektrum. Das Magazin der Hochschule Regensburg}, volume = {2012}, journal = {Spektrum. Das Magazin der Hochschule Regensburg}, number = {1}, organization = {Hochschule f{\"u}r Angewandte Wissenschaften Regensburg}, pages = {58}, language = {de} }