TY  - JOUR
A1  - van der Weerd, Bastiaan
A1  - Bierl, Rudolf
A1  - Matysik, Frank-Michael
T1  - Trends in Electrochemical Sensing of Blood Gases
T2  - Bioanalytical Reviews
N2  - The monitoring of partial pressures of the blood gases carbon dioxide (pCO2) and oxygen (pO2) is of great importance in clinical diagnostics. The measure of pCO2 and pO2 provides essential information about the patient’s metabolism, gas exchange, ventilation, and acid–base homeostasis. The conventional electrochemical methods for clinical blood gas analysis are based on the potentiometric Severinghaus sensor for carbon dioxide and the amperometric Clark sensor for oxygen. These techniques are well established and are only shortly discussed in this overview. However, in recent years a variety of modifications of these classical sensor concepts and new approaches of electrochemical sensing of pCO2 and pO2 have been introduced. This review summarizes recent developments in this field and discusses the potential for future applications in clinical blood gas analysis.
KW  - Blood gas analysis
KW  - Noninvasive blood gas sensor
KW  - Electrochemical sensor
KW  - Clinical analysis
Y1  - 2016
UR  - https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/1448
VL  - 6
SP  - 263
EP  - 280
PB  - Springer
CY  - Berlin
ER  -