TY - JOUR A1 - Horn, Lars-Christian A1 - Raptis, Georgios A1 - Fischer, Uta A1 - Hentschel, Bettina A1 - Köhler, U. A1 - Richter, Christine E. A1 - Martin, Rosemarie T1 - CD44-v6 concentrations in carcinoma of the uterine cervix: lack of prognostic significance T2 - Archives of Gynecology and Obstetrics N2 - Several kinds of cellular adhesion molecules, like different splicing variants of CD 44, have gained important as prognostic or markers for metastatic disease. Fresh frozen samples from 64 cervical carcinoma (CX) were stored in liquid nitrogen and examined using ELISA-technique, testing the prognostic impact. Normal cervical tissue served as control. CD 44-v6 concentration, was significant elevated in tumor tissue, when compared to the controls (P=0.04). There was no correlation to tumor stage (P=0.61), lymphovascular space involvement (P=0.075) or pelvic lymph node involvement (P=0.81). The CD 44-v6 concentration was not informative regarding recurrence-free and overall survival. Contrary to immunohistochemistry, the quantification of CD 44-v6 using ELISA-technique does not provide any further information. KW - Gebärmutterhalskrebs KW - Antigen CD44 Y1 - 2005 UR - https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/404 VL - 273 IS - 2 SP - 104 EP - 106 ER -