TY - JOUR A1 - Spiegelhalder, Kai A1 - Baumeister, Harald A1 - Al-Kamaly, Abdulwahab A1 - Bader, Martina A1 - Bauereiss, Natalie A1 - Benz, Fee A1 - Braun, Lina A1 - Buntrock, Claudia A1 - Burkhardt, Maike A1 - Cuijpers, Pim A1 - Domschke, Katharina A1 - Dülsen, Patrick A1 - Franke, Marvin A1 - Frase, Lukas A1 - Heber, Elena A1 - Helm, Kathrin A1 - Jentsch, Terry A1 - Johann, Anna A1 - Küchler, Ann-Marie A1 - Kuhn, Michael A1 - Lehr, Dirk A1 - Maun, Andy A1 - Morin, Charles M A1 - Moshagen, Morten A1 - Richter, Kneginja A1 - Schiel, Julian A1 - Simon, Laura A1 - Spille, Lukas A1 - Weeß, Hans-Günter A1 - Riemann, Dieter A1 - Ebert, David Daniel T1 - Comparative effectiveness of three versions of a stepped care model for insomnia differing in the amount of therapist support in internet-delivered treatment: study protocol for a pragmatic cluster randomised controlled trial (GET Sleep) JF - BMJ Open N2 - IntroductionIt is unclear how internet-delivered cognitive-behavioural therapy for insomnia (CBT-I) can be integrated into healthcare systems, and little is known about the optimal level of therapist guidance. The aim of this study is to investigate three different versions of a stepped care model for insomnia (IG1, IG2, IG3) versus treatment as usual (TAU). IG1, IG2 and IG3 rely on treatment by general practitioners (GPs) in the entry level and differ in the amount of guidance by e-coaches in internet-delivered CBT-I.Methods and analysisIn this randomised controlled trial, 4268 patients meeting International Classification of Diseases, Tenth Revision (ICD-10) criteria for insomnia will be recruited. The study will use cluster randomisation of GPs with an allocation ratio of 3:3:3:1 (IG1, IG2, IG3, TAU). In step 1 of the stepped care model, GPs will deliver psychoeducational treatment; in step 2, an internet-delivered CBT-I programme will be used; in step 3, GPs will refer patients to specialised treatment. Outcomes will be collected at baseline, and 4 weeks, 12 weeks and 6 months after baseline assessment. The primary outcome is insomnia severity at 6 months. An economic evaluation will be conducted and qualitative interviews will be used to explore barriers and facilitators of the stepped care model.Ethics and disseminationThe study protocol was approved by the Ethics Committee of the Medical Centre—University of Freiburg. The results of the study will be published irrespective of the outcome.Trial registration numberDRKS00021503. Y1 - 2022 U6 - https://doi.org/10.1136/bmjopen-2021-058212 SN - 2044-6055 VL - 12 IS - 8 PB - BMJ ER - TY - JOUR A1 - Kellner, Stefanie A1 - Richter, Kneginja T1 - Insomnie in der Schwangerschaft – eine systematische Übersichtsarbeit JF - Somnologie N2 - Insomnie und ein reduzierter Schlaf gehören zu den häufigsten Beschwerden, die im Verlauf einer Schwangerschaft auftreten können, vor allem im dritten Trimester. Rund 66–94 % aller Schwangeren geben Schlafprobleme an, die mit negativen physischen und psychischen Konsequenzen für das schwangere Individuum wie auch für das ungeborene Kind verbunden sind. Y1 - 2022 U6 - https://doi.org/10.1007/s11818-022-00342-y SN - 1432-9123 VL - 26 IS - 1 SP - 40 EP - 48 PB - Springer Science and Business Media LLC ER - TY - JOUR A1 - Weber, Franziska C. A1 - Danker-Hopfe, Heidi A1 - Dogan-Sander, Ezgi A1 - Frase, Lukas A1 - Hansel, Anna A1 - Mauche, Nicole A1 - Mikutta, Christian A1 - Nemeth, Diana A1 - Richter, Kneginja A1 - Schilling, Claudia A1 - Sebestova, Martina A1 - Spath, Marian M. A1 - Nissen, Christoph A1 - Wetter, Thomas C. T1 - Restless Legs Syndrome Prevalence and Clinical Correlates Among Psychiatric Inpatients BT - a multicenter study JF - Frontiers in Psychiatry N2 - BackgroundThere are only limited reports on the prevalence of restless legs syndrome (RLS) in patients with psychiatric disorders. The present study aimed to evaluate the prevalence and clinical correlates in psychiatric inpatients in Germany and Switzerland.MethodsThis is a multicenter cross-sectional study of psychiatric inpatients with an age above 18 years that were diagnosed and evaluated face-to-face using the International RLS Study Group criteria (IRLSSG) and the International RLS severity scale (IRLS). In addition to sociodemographic and biometric data, sleep quality and mood were assessed using the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity Index (ISI), the Epworth Sleepiness Scale (ESS), and the Patient Health Questionnaire (PHQ-9). In addition to univariate statistics used to describe and statistically analyze differences in variables of interest between patients with and without RLS, a logistic model was employed to identify predictors for the occurrence of RLS.ResultsThe prevalence of RLS in a sample of 317 psychiatric inpatients was 16.4%, and 76.9% of these were diagnosed with RLS for the first time. RLS severity was moderate to severe (IRLS ± SD: 20.3 ± 8.4). The prevalences in women (p = 0.0036) and in first-degree relatives with RLS (p = 0.0108) as well as the body mass index (BMI, p = 0.0161) were significantly higher among patients with RLS, while alcohol consumption was significantly lower in the RLS group. With the exception of atypical antipsychotics, treatment with psychotropic drugs was not associated with RLS symptoms. Regarding subjective sleep quality and mood, scores of the PSQI (p = 0.0007), ISI (p = 0.0003), and ESS (p = 0.0005) were higher in patients with RLS, while PHQ-9 scores were not different. A logistic regression analysis identified gender (OR 2.67; 95% CI [1.25; 5.72]), first-degree relatives with RLS (OR 3.29; 95% CI [1.11; 9.73], ESS score (OR 1.09; 95% CI [1.01; 1.17]), and rare alcohol consumption (OR 0.45; 95% CI [0.22; 0.94] as predictors for RLS.ConclusionsClinically significant RLS had a high prevalence in psychiatric patients. RLS was associated with higher BMI, impaired sleep quality, and lower alcohol consumption. A systematic assessment of restless legs symptoms might contribute to improve the treatment of psychiatric patients. Y1 - 2022 U6 - https://doi.org/10.3389/fpsyt.2022.846165 SN - 1664-0640 VL - 13 PB - Frontiers Media SA ER - TY - JOUR A1 - Licht, Christiane A1 - Ruttmann, Axel A1 - Hillemacher, Thomas A1 - Richter, Kneginja T1 - Use of repetitive transcranial magnetic stimulation in the treatment of catatonia JF - Journal of Psychiatry and Neuroscience Y1 - 2022 U6 - https://doi.org/10.1503/jpn.220052 SN - 1180-4882 VL - 47 IS - 4 PB - CMA Impact Inc. ER - TY - JOUR A1 - Richter, Kneginja A1 - Arzt, Michael T1 - COVID-19-Pandemie und Schlaf JF - Somnologie Y1 - 2022 U6 - https://doi.org/10.1007/s11818-022-00355-7 SN - 1432-9123 VL - 26 IS - 2 SP - 71 EP - 72 PB - Springer Science and Business Media LLC ER - TY - JOUR A1 - Licht, Christiane A1 - Metzger, Thomas W. J. A1 - Weisser, Roland A1 - Schloegl, Christian A1 - Richter, Kneginja T1 - TU-178. Maladjustment of pressure settings of programmable shunt valves by weak magnetic fields JF - Clinical Neurophysiology, Supplement Y1 - 2022 U6 - https://doi.org/10.1016/j.clinph.2022.07.082 SN - 1388-2457 VL - 141 SP - S31 PB - Elsevier BV ER - TY - JOUR A1 - Miloseva, Lence A1 - Richter, Kneginja T1 - Editorial: Impact of neurostimulation and psychotherapy on mental health JF - Frontiers in Psychology Y1 - 2022 U6 - https://doi.org/10.3389/fpsyg.2022.992634 SN - 1664-1078 VL - 13 PB - Frontiers Media SA ER - TY - JOUR A1 - Richter, Kneginja A1 - Rodenbeck, Andrea T1 - Aktuelle Entwicklungen in der Schlafforschung und Schlafmedizin – eine Einschätzung der AG „Chronobiologie“ JF - Somnologie Y1 - 2022 U6 - https://doi.org/10.1007/s11818-022-00368-2 SN - 1432-9123 VL - 26 IS - 3 SP - 152 EP - 154 PB - Springer Science and Business Media LLC ER -