@techreport{ZauterReindlRichteretal.2018, author = {Zauter, Sigrid and Reindl, Richard and Richter, Kneginja and Peter, Lukas}, title = {Onlineberatung M{\"u}digkeitsmilderung (OMM)}, volume = {2018}, number = {1}, organization = {Technische Hochschule N{\"u}rnberg, Insitut f{\"u}r e-Beratung}, doi = {10.34646/thn/ohmdok-551}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:92-opus4-5517}, pages = {25}, year = {2018}, abstract = {Ziel des Vorhabens war es, ein internetgest{\"u}tztes Programm zu entwickeln, das zur Pr{\"a}vention von Schlafst{\"o}rungen eingesetzt werden kann und verhaltensorientierte Bausteine zum besseren Umgang mit Schlafproblemen enth{\"a}lt. Neben einem Selbsttest zur ersten Einsch{\"a}tzung von Schlafst{\"o}rungen, einem Schlaftagebuch zur Kontrolle der Schlafeffizienz, setzt das Programm wesentlich auf eine individualisierte Onlineberatung, die Hilfe und Unterst{\"u}tzung bei der Verbesserung der Schlafeffizienz leisten und zur Verminderung der Symptome des SWD beitragen kann. Die geplanten Projektziele im Sinne der Verbesserung von Schlafst{\"o}rungen und M{\"u}digkeit durch Onlineschlaf-beratung wurden bei der Stichprobe, die das Beratungsprogramm vollst{\"a}ndig durchlaufen haben, erreicht.}, subject = {Computerunterst{\"u}tzte Kommunikation}, language = {de} } @article{FraseAckerCohrsetal.2019, author = {Frase, Lukas and Acker, Jens and Cohrs, Stefan and Danker-Hopfe, Heidi and Frohn, Corinna and G{\"o}der, Robert and Mauche, Nicole and Norra, Christine and Pollm{\"a}cher, Thomas and Richter, Kneginja and Riemann, Dieter and Schilling, Claudia and Weeß, Hans-G{\"u}nter and Wetter, Thomas C. and Nissen, Christoph}, title = {Empfehlungen zur Durchf{\"u}hrung einer Polygraphie oder Polysomnographie im Bereich Psychiatrie und Psychotherapie}, series = {Der Nervenarzt}, volume = {91}, journal = {Der Nervenarzt}, number = {9}, publisher = {Springer Science and Business Media LLC}, issn = {0028-2804}, doi = {10.1007/s00115-019-00855-2}, pages = {843 -- 853}, year = {2019}, abstract = {Ein- und Durchschlafst{\"o}rungen, nichterholsamer Schlaf oder erh{\"o}hte Tagesm{\"u}digkeit sind unspezifische Symptome von heute ca. 100 unterscheidbaren St{\"o}rungsbildern, die in der kommenden 11. Revision der Internationalen statistischen Klassifikation der Krankheiten (ICD-11) erstmals als eigenes Kapitel 7 „Schlaf-Wach-St{\"o}rungen" zusammengefasst werden. Mit Blick auf den Fachbereich Psychiatrie und Psychotherapie besteht ein bidirektionaler Zusammenhang zwischen Schlaf-Wach-St{\"o}rungen und psychischen Erkrankungen. Schlaf-Wach-St{\"o}rungen k{\"o}nnen einen unabh{\"a}ngigen Risikofaktor f{\"u}r das Entstehen einer psychischen Erkrankung darstellen und den Erkrankungsverlauf ung{\"u}nstig beeinflussen. Zudem k{\"o}nnen Schlaf-Wach-St{\"o}rungen einer psychischen Erkrankung auch als Fr{\"u}hsymptom vorausgehen und damit ein wichtiger Hinweis bei der Fr{\"u}herkennung sein. Zahlreiche Schlaf-Wach-St{\"o}rungen k{\"o}nnen anhand der Anamnese und {\"u}blicher klinischer Untersuchungen diagnostiziert werden. Bei spezielleren Fragestellungen k{\"o}nnen die Untersuchung in einem speziali-sierten Schlaflabor und die Behandlung in einem schlafmedizinischen Zentrum im Sinne einer gestuften Versorgung notwendig sein. Hier ist die Polysomnographie die wichtigste Untersuchungsmethode f{\"u}r die Differenzialdiagnostik, f{\"u}r deren Abrechnung {\"u}ber die Kostentr{\"a}ger heute in Deutschland jedoch keine gesetzliche Grundlage im Bereich neuro-psychiatrischer St{\"o}rungen besteht. Die vorliegende Arbeit fasst die aktuellen Leitlinien hinsichtlich der Kriterien f{\"u}r eine Untersuchung im Schlaflabor aus Sicht des Fachgebiets Psychiatrie und Psychotherapie zusammen und stellt daraus abgeleitet Forderungen f{\"u}r eine leitliniengerechte Diagnostik und Behandlung.}, language = {de} } @article{RichterBaumgaertnerNiklewskietal.2020, author = {Richter, Kneginja and Baumg{\"a}rtner, Lisa and Niklewski, G{\"u}nter and Peter, Lukas and K{\"o}ck, Melanie and Kellner, Stefanie and Hillemacher, Thomas and B{\"u}ttner-Teleaga, Antje}, title = {Sleep disorders in migrants and refugees}, series = {EPMA Journal}, volume = {11}, journal = {EPMA Journal}, number = {2}, publisher = {Springer Science and Business Media LLC}, issn = {1878-5077}, doi = {10.1007/s13167-020-00205-2}, pages = {251 -- 260}, year = {2020}, language = {en} } @article{SpiegelhalderBaumeisterAlKamalyetal.2022, author = {Spiegelhalder, Kai and Baumeister, Harald and Al-Kamaly, Abdulwahab and Bader, Martina and Bauereiss, Natalie and Benz, Fee and Braun, Lina and Buntrock, Claudia and Burkhardt, Maike and Cuijpers, Pim and Domschke, Katharina and D{\"u}lsen, Patrick and Franke, Marvin and Frase, Lukas and Heber, Elena and Helm, Kathrin and Jentsch, Terry and Johann, Anna and K{\"u}chler, Ann-Marie and Kuhn, Michael and Lehr, Dirk and Maun, Andy and Morin, Charles M and Moshagen, Morten and Richter, Kneginja and Schiel, Julian and Simon, Laura and Spille, Lukas and Weeß, Hans-G{\"u}nter and Riemann, Dieter and Ebert, David Daniel}, title = {Comparative effectiveness of three versions of a stepped care model for insomnia differing in the amount of therapist support in internet-delivered treatment: study protocol for a pragmatic cluster randomised controlled trial (GET Sleep)}, series = {BMJ Open}, volume = {12}, journal = {BMJ Open}, number = {8}, publisher = {BMJ}, issn = {2044-6055}, doi = {10.1136/bmjopen-2021-058212}, pages = {11}, year = {2022}, abstract = {IntroductionIt is unclear how internet-delivered cognitive-behavioural therapy for insomnia (CBT-I) can be integrated into healthcare systems, and little is known about the optimal level of therapist guidance. The aim of this study is to investigate three different versions of a stepped care model for insomnia (IG1, IG2, IG3) versus treatment as usual (TAU). IG1, IG2 and IG3 rely on treatment by general practitioners (GPs) in the entry level and differ in the amount of guidance by e-coaches in internet-delivered CBT-I.Methods and analysisIn this randomised controlled trial, 4268 patients meeting International Classification of Diseases, Tenth Revision (ICD-10) criteria for insomnia will be recruited. The study will use cluster randomisation of GPs with an allocation ratio of 3:3:3:1 (IG1, IG2, IG3, TAU). In step 1 of the stepped care model, GPs will deliver psychoeducational treatment; in step 2, an internet-delivered CBT-I programme will be used; in step 3, GPs will refer patients to specialised treatment. Outcomes will be collected at baseline, and 4 weeks, 12 weeks and 6 months after baseline assessment. The primary outcome is insomnia severity at 6 months. An economic evaluation will be conducted and qualitative interviews will be used to explore barriers and facilitators of the stepped care model.Ethics and disseminationThe study protocol was approved by the Ethics Committee of the Medical Centre—University of Freiburg. The results of the study will be published irrespective of the outcome.Trial registration numberDRKS00021503.}, language = {en} } @article{AckerBeckerCarusBuettnerTeleagaetal.2021, author = {Acker, Jens G. and Becker-Carus, C. and B{\"u}ttner-Teleaga, Antje and Cassel, Werner and Danker-Hopfe, Heidi and D{\"u}ck, Alexander and Frohn, Corinna and Hein, Holger and Penzel, Thomas and Rodenbeck, Andrea and Roenneberg, Till and Sauter, Cornelia and Weeß, Hans-G{\"u}nter and Zeitlhofer, Josef and Richter, Kneginja}, title = {The role of actigraphy in sleep medicine}, series = {Somnologie}, volume = {25}, journal = {Somnologie}, number = {2}, publisher = {Springer Science and Business Media LLC}, issn = {1432-9123}, doi = {10.1007/s11818-021-00306-8}, pages = {89 -- 98}, year = {2021}, abstract = {AbstractActigraphy has been used for more than 60 years to objectively measure sleep-wake rhythms. Improved modern devices are increasingly employed to diagnose sleep medicine disorders in the clinical setting. Although less accurate than polysomnography, the chief advantage of actigraphs lies in the cost-effective collection of objective data over prolonged periods of time under everyday conditions. Since the cost of wrist actigraphy is not currently reimbursed, this method has not enjoyed wide acceptance to date. The present article provides an overview of the main clinical applications of actigraphy, including the recommendations of specialist societies.}, language = {en} } @article{SpiegelhalderAckerBaumeisteretal.2020, author = {Spiegelhalder, Kai and Acker, Jens and Baumeister, Harald and B{\"u}ttner-Teleaga, Antje and Danker-Hopfe, Heidi and Ebert, David D. and Fietze, Ingo and Frase, Lukas and Klein, Sarah and Lehr, Dirk and Maun, Andy and Mertel, Isabella and Richter, Kneginja and Riemann, Dieter and Sauter, Cornelia and Schilling, Claudia and Schlarb, Angelika A. and Specht, Markus and Steinmetz, Lisa and Weeß, Hans G. and Cr{\"o}nlein, Tatjana}, title = {Digitale Behandlungsangebote f{\"u}r Insomnie - eine {\"U}bersichtsarbeit}, series = {Somnologie}, volume = {24}, journal = {Somnologie}, number = {2}, publisher = {Springer Science and Business Media LLC}, issn = {1432-9123}, doi = {10.1007/s11818-020-00238-9}, pages = {106 -- 114}, year = {2020}, abstract = {ZusammenfassungDigital angebotene psychologische Interventionen gegen Schlafst{\"o}rungen sind aktuell ein sehr intensiv bearbeitetes Forschungsthema. In dieser {\"U}bersichtsarbeit werden Originalarbeiten und Metaanalysen zu diesem Thema zusammengefasst. Hierbei zeigt sich, dass die internetbasierte kognitive Verhaltenstherapie f{\"u}r Insomnie (KVT-I) bei Erwachsenen durchweg sehr effektiv ist mit allenfalls leicht geringeren Effektst{\"a}rken als die gleiche Behandlung mit physischer Pr{\"a}senz von Therapeuten und Patienten. Behandlungseffekte zeigen sich dabei auch f{\"u}r sekund{\"a}re Outcome-Parameter wie Depressivit{\"a}t, Angst, Fatigue und Lebensqualit{\"a}t. Hingegen lassen die Forschung zur Wirksamkeit der internetbasierten KVT‑I bei Erwachsenen mit komorbiden psychischen St{\"o}rungen oder k{\"o}rperlichen Erkrankungen sowie die Forschung zur Frage, wieviel Therapeutenkontakt in die Behandlung integriert werden sollte, anscheinend noch keine abschließenden Antworten zu. In diesen Bereichen scheint weitere Forschung notwendig zu sein scheint.}, language = {de} } @article{PourhassanSarginsonHitzletal.2023, author = {Pourhassan, Jasmin and Sarginson, Jane and Hitzl, Wolfgang and Richter, Kneginja}, title = {Cognitive function in soccer athletes determined by sleep disruption and self-reported health, yet not by decision-reinvestment}, series = {Frontiers in Neurology}, volume = {13}, journal = {Frontiers in Neurology}, publisher = {Frontiers Media SA}, issn = {1664-2295}, doi = {10.3389/fneur.2022.872761}, pages = {1 -- 13}, year = {2023}, abstract = {BackgroundSleep disruption (SD) increases sympathetic activity and cortisol secretion, and delays cognitive functions such as reaction-time (RT). Sympathetic activity of disturbed sleepers, is similar to those of so-called decision-reinvesters. Decision-reinvestment refers to traits in individuals with greater tendency to ruminate and reinvest in their decisions, with significant decrease in both motor-control and cognitive performance. Decision-making quality is a crucial attribute to athletic performance which relies on RT. Consequently, SD affects pitch-performance negatively, particularly in decision-reinvesters. This observational pilot-study examined the relationship between SD and cognitive function, perceived health, as well as reinvestment strategies. The hypothesis was that athletes with lower SD perceive their health better, report lower stress levels, perform better in cognitive tasks, and show lower tendency for decision-reinvestment.MethodsTwenty-one football player recorded their sleep with fit-trackers for 7 nights. Participants self-reported their mental and physical health, decision-reinvestment strategy, sleep behaviour, and perceived stress levels. Athletes then performed a set of cognitive tests to examine memory function (Backwards Corsi), selective attention (STROOP), and cognitive flexibility (Wisconsin Card Sorting Test, WCST). Normality was tested with a Shapiro-Wilk test, and analysed with a Pearson's or Spearman's correlation test.ResultsSignificant correlation appeared between extended sleep-interruptions and Backwards Corsi RT, r = 0.66, p = 0.010, as further in total sleep time and wellbeing r = 0.50, p = 0.029. A negative correlation exist in regard of pain scores and Backwards Corsi scores r = -0.57, p = 0.110. Physical health correlated with error-rates in the WCST, r = 0.69, p ≤ 0.001. Also, reinvestment negatively correlated with physical health, r = -0.80, p ≤ 0.001.ConclusionWellbeing relies on total sleep-time. Athletes with extended sleep-interruptions are slower in recalling memory, and those with greater reported pain have lower memory scores. Participants who rate physical health greater, have more error-rates in the WCST; indicating that cognitive flexibility is enhanced in individuals with inferior perceived health. However, individuals with lower physical health scores also have greater tendency to ruminate and reinvest in decisions, suggesting interrelation between reinvestment and physical health.}, language = {en} } @article{KellnerRichter2022, author = {Kellner, Stefanie and Richter, Kneginja}, title = {Insomnie in der Schwangerschaft - eine systematische {\"U}bersichtsarbeit}, series = {Somnologie}, volume = {26}, journal = {Somnologie}, number = {1}, publisher = {Springer Science and Business Media LLC}, issn = {1432-9123}, doi = {10.1007/s11818-022-00342-y}, pages = {40 -- 48}, year = {2022}, abstract = {Insomnie und ein reduzierter Schlaf geh{\"o}ren zu den h{\"a}ufigsten Beschwerden, die im Verlauf einer Schwangerschaft auftreten k{\"o}nnen, vor allem im dritten Trimester. Rund 66-94 \% aller Schwangeren geben Schlafprobleme an, die mit negativen physischen und psychischen Konsequenzen f{\"u}r das schwangere Individuum wie auch f{\"u}r das ungeborene Kind verbunden sind.}, language = {de} } @article{RichterAckerKamcevetal.2011, author = {Richter, Kneginja and Acker, Jens and Kamcev, Nikola and Bajraktarov, Stojan and Piehl, Anja and Niklewski, G{\"u}nter}, title = {Recommendations for the prevention of breast cancer in shift workers}, series = {EPMA Journal}, volume = {2011}, journal = {EPMA Journal}, number = {2}, doi = {10.34646/thn/ohmdok-42}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:92-opus-923}, pages = {351 -- 356}, year = {2011}, abstract = {Abstract The functioning of the human body is regulated by the rhythmical change between rest and activity. The SCN (suprachiasmatic nucleus) is responsible for the central control of the biorhythm and the genetic prediction of the individual chronotype, whereas peripheral time cues such as light, social contacts and times of meals modulate the rhythmical activity of the body. Shift workers suffer from a disruption of the sleep-wake rhythm, insomnia and a lack of melatonin. These factors might trigger the development of breast cancer in female shift workers. The growing amount of data which indicate the high risk of breast cancer in female shift workers demonstrates the need for the implementation of prevention strategies against insomnia in shift workers. These strategies include regular sleep education courses on the prevention of sleep disorders in companies. The individual chronotype could be an important predictor for the adaptability to shift work.}, subject = {Schichtarbeit}, language = {en} } @article{RetzerFeilReindletal.2021, author = {Retzer, Lukas and Feil, Monika and Reindl, Richard and Richter, Kneginja and Lehmann, Robert and Stemmler, Mark and Graessel, Elmar}, title = {Anonymous online cognitive behavioral therapy for sleep disorders in shift workers}, series = {Trials}, volume = {22}, journal = {Trials}, number = {1}, publisher = {Springer Science and Business Media LLC}, issn = {1745-6215}, doi = {10.1186/s13063-021-05437-9}, pages = {7}, year = {2021}, abstract = {AbstractBackgroundMany shift workers suffer from sleep issues, which negatively affect quality of life and performance. Scientifically evaluated, structured programs for prevention and treatment are scarce. We developed an anonymous online cognitive behavioral therapy for insomnia (CBT-I) program. After successful completion of a feasibility study, we now start this prospective, randomized, controlled superiority trial to compare outcomes of two parallel groups, namely an intervention group and a waiting-list control-group. Additionally, we will compare these outcomes to those of a face-to-face CBT-I outpatient sample.MethodsCollaborating companies will offer our anonymous online intervention to their shift-working employees. Company physicians and counseling services will screen those interested for inclusion and exclusion criteria. Participants will receive access to our online service, where they will complete psychometric assessment and receive random assignment to either the intervention group or the waiting-list control group. Participants and providers will be aware of the group assignment. We aim to allocate at leastN= 60 participants to the trial. The intervention consists of psychoeducation, sleep restriction, stimulus control, relaxation techniques, and individual feedback delivered via four e-mail contacts. During the intervention, as well as during the waiting period, participants will fill out weekly sleep diaries. Immediately after completion of the program, the post-intervention assessment takes place. Participants in the control group will be able to participate in the program after all study assessments. To recruit an additional sample, collaborating outpatient sleep clinics will provide six sessions of standard face-to-face CBT-I to an ad hoc sample of shift working patients. We expect both the online and the face-to-face CBT-I interventions to have beneficial effects compared to the control group on the following primary outcomes: self-reported symptoms of depression and insomnia, sleep quality, and daytime sleepiness.ConclusionsThe online intervention allows shift workers to follow a CBT-I program independently of their working schedule and location. Forthcoming results might contribute to further improvement of prevention and therapy of sleep issues in shift workers.Trial registrationGerman Clinical Trials Register DRKSDRKS00017777. Registered on 14 January 2020—retrospectively registered.}, language = {en} } @article{RichterZimniTomovaetal.2021, author = {Richter, Kneginja and Zimni, Melanie and Tomova, Iva and Retzer, Lukas and H{\"o}fig, Joachim and Kellner, Stefanie and Fries, Carla and Bernstein, Karina and Hitzl, Wolfgang and Hillemacher, Thomas and Miloseva, Lence and Acker, Jens}, title = {Insomnia Associated with Tinnitus and Gender Differences}, series = {International Journal of Environmental Research and Public Health}, volume = {18}, journal = {International Journal of Environmental Research and Public Health}, number = {6}, publisher = {MDPI AG}, issn = {1660-4601}, doi = {10.3390/ijerph18063209}, pages = {10}, year = {2021}, abstract = {Chronic tinnitus causes a decrease in well-being and can negatively affect sleep quality. It has further been indicated that there are clinically relevant gender differences, which may also have an impact on sleep quality. By conducting a retrospective and explorative data analysis for differences in patients with tinnitus and patients diagnosed with tinnitus and insomnia, hypothesized differences were explored in the summed test scores and on item-level of the validated psychometric instruments. A cross-sectional study was conducted collecting data from a sample of tinnitus patients (n = 76). Insomnia was diagnosed in 49 patients. Gender differences were found on aggregated test scores of the MADRS and BDI with men scoring higher than women, indicating higher depressive symptoms in men. Women stated to suffer more from headaches (p \< 0.003), neck pain (p \< 0.006) and nervousness as well as restlessness (p \< 0.02). Women also reported an increase in tinnitus loudness in response to stress compared to men (p \< 0.03). Male individuals with tinnitus and insomnia have higher depression scores and more clinically relevant depressive symptoms than women, who suffer more from psychosomatic symptoms. The results indicate a need for a targeted therapy of depressive symptoms in male patients and targeted treatment of psychosomatic symptoms, stress-related worsening of insomnia and tinnitus in women.}, language = {en} } @article{WeberDankerHopfeDoganSanderetal.2022, author = {Weber, Franziska C. and Danker-Hopfe, Heidi and Dogan-Sander, Ezgi and Frase, Lukas and Hansel, Anna and Mauche, Nicole and Mikutta, Christian and Nemeth, Diana and Richter, Kneginja and Schilling, Claudia and Sebestova, Martina and Spath, Marian M. and Nissen, Christoph and Wetter, Thomas C.}, title = {Restless Legs Syndrome Prevalence and Clinical Correlates Among Psychiatric Inpatients}, series = {Frontiers in Psychiatry}, volume = {13}, journal = {Frontiers in Psychiatry}, publisher = {Frontiers Media SA}, issn = {1664-0640}, doi = {10.3389/fpsyt.2022.846165}, pages = {15}, year = {2022}, abstract = {BackgroundThere are only limited reports on the prevalence of restless legs syndrome (RLS) in patients with psychiatric disorders. The present study aimed to evaluate the prevalence and clinical correlates in psychiatric inpatients in Germany and Switzerland.MethodsThis is a multicenter cross-sectional study of psychiatric inpatients with an age above 18 years that were diagnosed and evaluated face-to-face using the International RLS Study Group criteria (IRLSSG) and the International RLS severity scale (IRLS). In addition to sociodemographic and biometric data, sleep quality and mood were assessed using the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity Index (ISI), the Epworth Sleepiness Scale (ESS), and the Patient Health Questionnaire (PHQ-9). In addition to univariate statistics used to describe and statistically analyze differences in variables of interest between patients with and without RLS, a logistic model was employed to identify predictors for the occurrence of RLS.ResultsThe prevalence of RLS in a sample of 317 psychiatric inpatients was 16.4\%, and 76.9\% of these were diagnosed with RLS for the first time. RLS severity was moderate to severe (IRLS ± SD: 20.3 ± 8.4). The prevalences in women (p = 0.0036) and in first-degree relatives with RLS (p = 0.0108) as well as the body mass index (BMI, p = 0.0161) were significantly higher among patients with RLS, while alcohol consumption was significantly lower in the RLS group. With the exception of atypical antipsychotics, treatment with psychotropic drugs was not associated with RLS symptoms. Regarding subjective sleep quality and mood, scores of the PSQI (p = 0.0007), ISI (p = 0.0003), and ESS (p = 0.0005) were higher in patients with RLS, while PHQ-9 scores were not different. A logistic regression analysis identified gender (OR 2.67; 95\% CI [1.25; 5.72]), first-degree relatives with RLS (OR 3.29; 95\% CI [1.11; 9.73], ESS score (OR 1.09; 95\% CI [1.01; 1.17]), and rare alcohol consumption (OR 0.45; 95\% CI [0.22; 0.94] as predictors for RLS.ConclusionsClinically significant RLS had a high prevalence in psychiatric patients. RLS was associated with higher BMI, impaired sleep quality, and lower alcohol consumption. A systematic assessment of restless legs symptoms might contribute to improve the treatment of psychiatric patients.}, language = {en} }