@article{SchmidtAlbertRitthaleretal.2021, author = {Schmidt, Ina and Albert, Jacob and Ritthaler, Marina and Papastavrou, Areti and Steinmann, Paul}, title = {Bone fracture healing within a continuum bone remodelling framework}, series = {Computer Methods in Biomechanics and Biomedical Engineering}, volume = {25 (2022)}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, number = {9}, publisher = {Informa UK Limited}, issn = {1476-8259}, doi = {10.1080/10255842.2021.1998465}, pages = {1040 -- 1050}, year = {2021}, abstract = {Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation.}, language = {en} }