TY - JOUR A1 - Schmidt, Ina A1 - Albert, Jacob A1 - Ritthaler, Marina A1 - Papastavrou, Areti A1 - Steinmann, Paul T1 - Bone fracture healing within a continuum bone remodelling framework T2 - Computer Methods in Biomechanics and Biomedical Engineering N2 - Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation. KW - bone remodelling KW - healing KW - bone fracture KW - femur head KW - finite element method Y1 - 2021 UR - https://opus4.kobv.de/opus4-ohm/frontdoor/index/index/docId/1409 SN - 1476-8259 VL - 25 (2022) IS - 9 SP - 1040 EP - 1050 PB - Informa UK Limited ER -