TY - JOUR A1 - Papastavrou, Areti A1 - Schmidt, Ina A1 - Steinmann, Paul T1 - On biological availability dependent bone remodeling T2 - Computer Methods in Biomechanics and Biomedical Engineering N2 - Modeling the evolution of bone density is relevant for understanding, simulation and possible prediction of bone response to external and internal influences. In this work we present a formulation for the bone density evolution process that takes into account not only the commonly considered mechanical stimulus, but, as novelty, also the influence of the availability of nutrients and hormones, with its implementation pursued within the finite element method. A simple uni-axial extension test is used to illustrate and compare our novel model against the classical approach. The results of the proposed modified model are promising for application to real-life problems. KW - bone remodeling KW - density change KW - finite element method Y1 - 2020 UR - https://opus4.kobv.de/opus4-ohm/frontdoor/index/index/docId/1407 SN - 1476-8259 VL - 23 (2020) PB - Informa UK Limited ER -