35R30 Inverse problems
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We consider an inverse problem arising in laser-induced thermotherapy, a minimally invasive method for cancer treatment, in which cancer tissue is destroyed by coagulation. For the dosage planning numerical simulation plays an important role. To this end a crucial problem is to identify the thermal growth kinetics of the coagulated zone. Mathematically, this problem is a nonlinear and nonlocal parabolic heat source inverse problem. The solution to this inverse problem is defined as the minimizer of a non-convex cost functional. The existence of the minimizer is proven. We derive the Gateaux derivative of the cost functional, which is based on the adjoint system, and use it for a numerical approximation of the optimal coefficient.
The goal of this paper is a mathematical investigation of dilatometer experiments. These are used to detect the kinetics
of solid-solid phase transitions in steel upon cooling from the high temperature phase. Usually, the data are only used for measuring
the start and end temperature of the phase transition. In the case of several coexisting product phases, expensive microscopic
investigations have to be performed to obtain the resulting fractions of the different phases. In contrast, it is shown in this paper that in the case of at most two product phases the complete phase transition kinetics including the final phase fractions are uniquely determined by the dilatometer data. Numerical results confirm the theoretical result.