Comparing Discrete and Piecewise Affine Differential Equation Models of Gene Regulatory Networks
Please always quote using this URN:urn:nbn:de:0296-matheon-10090
- We compare the discrete asynchronous logical modeling formalism for gene regulatory networks due to R. Thomas with piecewise-affine differential equation models. We show that although the two approaches are based on equivalent information, the resulting qualitative dynamics are different.
| Author: | Shahrad Jamshidi, Heike Siebert, Alexander Bockmayr |
|---|---|
| URN: | urn:nbn:de:0296-matheon-10090 |
| Referee: | Peter Deuflhard |
| Document Type: | Preprint, Research Center Matheon |
| Language: | English |
| Date of first Publication: | 2012/01/24 |
| Release Date: | 2012/01/24 |
| Tag: | Discrete model; Gene regulatory network; Piecewise affine model |
| Institute: | Freie Universität Berlin |
| Research Center Matheon | |
| MSC-Classification: | 92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C42 Systems biology, networks |
| Preprint Number: | 870 |
