Comparing Discrete and Piecewise Affine Differential Equation Models of Gene Regulatory Networks
Please always quote using this URN:urn:nbn:de:0296-matheon-10090
- We compare the discrete asynchronous logical modeling formalism for gene regulatory networks due to R. Thomas with piecewise-affine differential equation models. We show that although the two approaches are based on equivalent information, the resulting qualitative dynamics are different.
Author: | Shahrad Jamshidi, Heike Siebert, Alexander Bockmayr |
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URN: | urn:nbn:de:0296-matheon-10090 |
Referee: | Peter Deuflhard |
Document Type: | Preprint, Research Center Matheon |
Language: | English |
Date of first Publication: | 2012/01/24 |
Release Date: | 2012/01/24 |
Tag: | Discrete model; Gene regulatory network; Piecewise affine model |
Institute: | Research Center Matheon |
Freie Universität Berlin | |
MSC-Classification: | 92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C42 Systems biology, networks |
Preprint Number: | 870 |