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Comparing Discrete and Piecewise Affine Differential Equation Models of Gene Regulatory Networks

Please always quote using this URN:urn:nbn:de:0296-matheon-10090
  • We compare the discrete asynchronous logical modeling formalism for gene regulatory networks due to R. Thomas with piecewise-affine differential equation models. We show that although the two approaches are based on equivalent information, the resulting qualitative dynamics are different.

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Metadaten
Author:Shahrad Jamshidi, Heike Siebert, Alexander Bockmayr
URN:urn:nbn:de:0296-matheon-10090
Referee:Peter Deuflhard
Document Type:Preprint, Research Center Matheon
Language:English
Date of first Publication:2012/01/24
Release Date:2012/01/24
Tag:Discrete model; Gene regulatory network; Piecewise affine model
Institute:Research Center Matheon
Freie Universität Berlin
MSC-Classification:92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C42 Systems biology, networks
Preprint Number:870
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