• search hit 259 of 1103
Back to Result List

Modeling of rhythmic patterns in hippocampus

Please always quote using this URN:urn:nbn:de:0296-matheon-9831
  • We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the individual level, each neuron is modeled by FitzHugh-Nagumo equations. Three basic rhythmic patterns are observed: gamma-rhythm in which the fast neurons are uniformly spiking, theta-rhythm in which the individual spikes are separated by quiet epochs, and theta/gamma rhythm with repeated patches of spikes. We analyze the influence of asymmetry of synaptic strengths on the synchronization in the network and demonstrate that strong asymmetry reduces the variety of available dynamical states. The model network exhibits multistability; this results in occurrence of hysteresis in dependence on the conductances of individual connections. We show that switching between different rhythmic patterns in the network depends on the degree of synchronization between the slow cells.

Download full text files

Export metadata

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Anastasia Lavrova, Michael Zaks, Lutz Schimansky-Geier
URN:urn:nbn:de:0296-matheon-9831
Referee:Alexander Mielke
Document Type:Preprint, Research Center Matheon
Language:English
Date of first Publication:2012/01/20
Release Date:2012/01/20
Tag:Synchronization; multistability
Institute:Humboldt-Universität zu Berlin
MSC-Classification:92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92-00 General reference works (handbooks, dictionaries, bibliographies, etc.)
92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C20 Neural biology
Preprint Number:864
Verstanden ✔
Diese Webseite verwendet technisch erforderliche Session-Cookies. Durch die weitere Nutzung der Webseite stimmen Sie diesem zu. Unsere Datenschutzerklärung finden Sie hier.