TY - JOUR A1 - Hubl, Moritz A1 - Atta, Raghied M. A1 - Kaufhold, Robin A1 - Wang, Bei A1 - Ngo, Ha Duong ED - Chronopoulou, Laura T1 - Nano-Materials-Based Printed Glucose Sensor for Use in Incontinence Products for Health-Care Applications JF - Micro N2 - Our recent development of a wireless humidity sensor system embedded in incontinence products enables new sensor applications to diagnose and supervise geriatric diseases (i.e., age-related diabetes mellitus type II). The measurement of glucose in urine, so-called glucosuria, is an early indicator for an incipient diabetes mellitus disease, whose symptoms are often age-related but misjudged. In this paper, an incontinence glucose sensor is printed with biocompatible ink and Prussian blue as an electron mediator on foil and functionalized with immobilized glucose oxidase. Inkjet printing of multiple layers of Nafion prevents large interference substances from diffusing into the measuring electrode and allows precise adjustment of the linear working range, which is significantly different from blood glucose measurement. Performance tests show the potential to detect minimum glucose values and store the sensor over a prolonged period at room temperature. The printed glucose sensor can be embedded into the absorber material of incontinence products, where capillary forces transport the urine analyte to the detection area. An attached readout module with an integrated potentiostat measures the glucose concentration in urine, which is transmitted wirelessly with incontinence events and stored in a cloud service for further analysis by medical staff and care workers. KW - Glucose-Sensor KW - printed glucose sensor KW - urine glucose sensor KW - printed electronics KW - Prussian blue mediator KW - electrochemic biosensor KW - glucosuria KW - diabetes mellitus KW - incontinence sensor KW - Polymerelektronik KW - Inkontinenz Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:523-18074 SN - 2673-8023 VL - 3 IS - 2 SP - 521 EP - 536 PB - MDPI ER - TY - JOUR A1 - Hubl, Moritz A1 - Atta, Raghied M. A1 - Kaufhold, Robin A1 - Wang, Bei A1 - Ngo, Ha Duong ED - Chronopoulou, Laura T1 - Nano-Materials-Based Printed Glucose Sensor for Use in Incontinence Products for Health-Care Applications JF - Micro N2 - Our recent development of a wireless humidity sensor system embedded in incontinence products enables new sensor applications to diagnose and supervise geriatric diseases (i.e., age-related diabetes mellitus type II). The measurement of glucose in urine, so-called glucosuria, is an early indicator for an incipient diabetes mellitus disease, whose symptoms are often age-related but misjudged. In this paper, an incontinence glucose sensor is printed with biocompatible ink and Prussian blue as an electron mediator on foil and functionalized with immobilized glucose oxidase. Inkjet printing of multiple layers of Nafion prevents large interference substances from diffusing into the measuring electrode and allows precise adjustment of the linear working range, which is significantly different from blood glucose measurement. Performance tests show the potential to detect minimum glucose values and store the sensor over a prolonged period at room temperature. The printed glucose sensor can be embedded into the absorber material of incontinence products, where capillary forces transport the urine analyte to the detection area. An attached readout module with an integrated potentiostat measures the glucose concentration in urine, which is transmitted wirelessly with incontinence events and stored in a cloud service for further analysis by medical staff and care workers. KW - Glucose KW - printed glucose sensor KW - urine glucose sensor KW - printed electronics KW - Prussian blue mediator KW - electrochemic biosensor KW - glucosuria KW - diabetes mellitus KW - incontinence sensor KW - Harn KW - 3D-Druck KW - Biosensor KW - Glucose-Sensor KW - Glucosurie KW - Diabetes mellitus KW - Harninkontinenz Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:523-17140 SN - 2673-8023 VL - 3 IS - 2 SP - 521 EP - 536 PB - MDPI ER -