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A complex intervention to promote prevention of delirium in older adults by targeting caregiver’s participation during and after hospital discharge – study protocol of the TRAnsport and DElirium in older people (TRADE) project

  • Background: Among potentially modifiable risk factors for delirium, transfers between wards, hospitals and other facilities have been mentioned with low evidence. TRADE (TRAnsport and DElirium in older people) was set up to investigate i) the impact of transfer and/or discharge on the onset of delirium in older adults and ii) feasibility and acceptance of a developed complex intervention targeting caregiver’s participation during and after hospital discharge or transfer on cognition and the onset of delirium in older adults. Methods: The study is designed according to the guidelines of the UK Medical Research Council (MRC) for development and evaluation of complex interventions and comprises two steps: development and feasibility/piloting. The development phase includes i) a multicenter observational prospective cohort study to assess delirium incidence and cognitive decline associated with transfer and discharge, ii) a systematic review of the literature, iii) stakeholder focus group interviews and iv) an expert workshop followed byBackground: Among potentially modifiable risk factors for delirium, transfers between wards, hospitals and other facilities have been mentioned with low evidence. TRADE (TRAnsport and DElirium in older people) was set up to investigate i) the impact of transfer and/or discharge on the onset of delirium in older adults and ii) feasibility and acceptance of a developed complex intervention targeting caregiver’s participation during and after hospital discharge or transfer on cognition and the onset of delirium in older adults. Methods: The study is designed according to the guidelines of the UK Medical Research Council (MRC) for development and evaluation of complex interventions and comprises two steps: development and feasibility/piloting. The development phase includes i) a multicenter observational prospective cohort study to assess delirium incidence and cognitive decline associated with transfer and discharge, ii) a systematic review of the literature, iii) stakeholder focus group interviews and iv) an expert workshop followed by a Delphi survey. Based on this information, a complex intervention to better and systematically involve family caregivers in discharge and transport was developed. The intervention will be tested in a pilot study using a stepped wedge design with a detailed process and health economic evaluation. The study is conducted at four acute care hospitals in southwest Germany. Primary endpoints are the delirium incidence and cognitive function. Secondary endpoints include prevalence of caregiver companionship, functional decline, cost and cost effectiveness, quality of discharge management and quality of admission management in admitting hospitals or nursing homes. Data will be collected prior to discharge as well as after 3, 7 and 90 days.show moreshow less

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Metadaten
Author:Christoph LeinertORCiD, Simone Brefka, Ulrike Braisch, Natascha Denninger, Martin Müller, Petra BenzingerORCiDGND, Jürgen M. BauerGND, Anke Bahrmann, Norbert Frey, Hugo Katus, Tobias Geisler, Gerhard Eschweiler, Jochen Klaus, Thomas Seufferlein, Konrad Schütze, Florian Gebhard, Jens Dreyhaupt, Rainer Muche, Kathrin Pahmeier, Janine Biermann-Stallwitz, Jürgen Wasem, Lena Flagmeier, Dhayana Dallmeier, Michael Denkinger
URL / DOI:http://doi.org/10.1186/s12877-021-02585-0
Parent Title (English):BMC Geriatrics
Publisher:Biomed Central
Place of publication:London
Document Type:Article
Language:English
Tag:Delirium; Protocol
Volume:2021
Issue:21
Article Number:646
Number of pages:15 Seiten
First Page:1
Last Page:15
Institutes:IGG - Institut für Gesundheit und Generationen
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik
Open Access:open_access
Research focus:FSP4: Soziale Innovationen
Publication Lists:Benzinger, Petra
Publication reviewed:begutachtet
Release Date:2021/11/24
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