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CPR Guideline Chest Compression Depths May Exceed Requirements for Optimal Physiological Response

  • A twelve-animal porcine study dataset was retrospectively analyzed to assess associations between chest compression (CC) depth, systolic blood pressure (SBP) and end-tidal carbon dioxide (EtCO2). Manual CCs were applied for 7 two-minute episodes, at CC depths between 10mm-55mm. A rolling 15s analysis window was applied to the continuous signals. Mean peak values were calculated for each window. Correlation analysis was applied to assess strength of association. Optimal CC depth to achieve physiological targets was determined via cut-off analysis. A total of 672 observations for each variable were available for analysis. Pearson correlations (95% confidence interval; p-value) between CC depth and both SBP and ETCO2 were 0.84 (0.82, 0.86; p < 0.001) and 0.75 (0.71, 0.78; p < 0.001) respectively. Optimal CC depth cutoff (sensitivity, specificity) to achieve SBP ≥ 100mmHg and EtCO2 ≥ 10mmHg was 33 mm (98.29%, 88.94%) and 20mm (95.08%, 78.30%) respectively. A reasonable relationship between CC depth and physiological response wasA twelve-animal porcine study dataset was retrospectively analyzed to assess associations between chest compression (CC) depth, systolic blood pressure (SBP) and end-tidal carbon dioxide (EtCO2). Manual CCs were applied for 7 two-minute episodes, at CC depths between 10mm-55mm. A rolling 15s analysis window was applied to the continuous signals. Mean peak values were calculated for each window. Correlation analysis was applied to assess strength of association. Optimal CC depth to achieve physiological targets was determined via cut-off analysis. A total of 672 observations for each variable were available for analysis. Pearson correlations (95% confidence interval; p-value) between CC depth and both SBP and ETCO2 were 0.84 (0.82, 0.86; p < 0.001) and 0.75 (0.71, 0.78; p < 0.001) respectively. Optimal CC depth cutoff (sensitivity, specificity) to achieve SBP ≥ 100mmHg and EtCO2 ≥ 10mmHg was 33 mm (98.29%, 88.94%) and 20mm (95.08%, 78.30%) respectively. A reasonable relationship between CC depth and physiological response was observed. Optimal SBP and EtCO2 cut-offs were achieved significantly below guideline depths. Furthermore, cut-off analysis suggests a disparity between CC depth and physiological targets.show moreshow less

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Metadaten
Author:Olibhear McAlister, Daniel GüldenringORCiD, Dewar D. FinlayORCiD, Raymond R. BondORCiD, Hannah Torney, Ben McCarter, Laura Davis, Paul Crawford, Adam Harvey
DOI:https://doi.org/10.22489/CinC.2018.116
Identifier:9781728109589 OPAC HS OPAC extern
Identifier:2325-887X OPAC HS OPAC extern
Parent Title (English):Computing in Cardiology Conference (CinC)
Publisher:IEEE
Place of publication:Piscataway
Editor:Christine Pickett
Document Type:conference proceeding (volume)
Conference:2018 Computing in Cardiology Conference (CinC) 23-26. Sept. 2018, Maastricht, Netherlands
Language:English
Date of Publication (online):2019/06/24
Year of first Publication:2018
Tag:Biomedizinische Signalverarbeitung
Biomedical Signal Processing
Volume:45
Number of pages:4 Seiten
Institutes:Fakultät Elektrotechnik
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften
Publication Lists:Güldenring, Daniel
Publication reviewed:begutachtet
Release Date:2021/02/15
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