TY - GEN A1 - McAlister, Olibhear A1 - Güldenring, Daniel A1 - Finlay, Dewar D. A1 - Bond, Raymond R. A1 - Torney, Hannah A1 - McCarter, Ben A1 - Davis, Laura A1 - Crawford, Paul A1 - Harvey, Adam A2 - Pickett, Christine T1 - CPR Guideline Chest Compression Depths May Exceed Requirements for Optimal Physiological Response T2 - Computing in Cardiology Conference (CinC) N2 - A twelve-animal porcine study dataset was retrospectively analyzed to assess associations between chest compression (CC) depth, systolic blood pressure (SBP) and end-tidal carbon dioxide (EtCO2). Manual CCs were applied for 7 two-minute episodes, at CC depths between 10mm-55mm. A rolling 15s analysis window was applied to the continuous signals. Mean peak values were calculated for each window. Correlation analysis was applied to assess strength of association. Optimal CC depth to achieve physiological targets was determined via cut-off analysis. A total of 672 observations for each variable were available for analysis. Pearson correlations (95% confidence interval; p-value) between CC depth and both SBP and ETCO2 were 0.84 (0.82, 0.86; p < 0.001) and 0.75 (0.71, 0.78; p < 0.001) respectively. Optimal CC depth cutoff (sensitivity, specificity) to achieve SBP ≥ 100mmHg and EtCO2 ≥ 10mmHg was 33 mm (98.29%, 88.94%) and 20mm (95.08%, 78.30%) respectively. A reasonable relationship between CC depth and physiological response was observed. Optimal SBP and EtCO2 cut-offs were achieved significantly below guideline depths. Furthermore, cut-off analysis suggests a disparity between CC depth and physiological targets. KW - Biomedizinische Signalverarbeitung KW - Biomedical Signal Processing Y1 - 2019 UR - https://opus4.kobv.de/opus4-hs-kempten/frontdoor/index/index/docId/660 SN - 9781728109589 SN - 2325-887X VL - 45 PB - IEEE CY - Piscataway ER -