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Background
Ultrafine particles (≤100 nm diameter) may have a higher toxicity than larger particles but are still not regulated nor part of routine air pollution monitoring. So far, health effects of long-term exposure to ambient ultrafine particles are not well understood, owing to a lack of exposure data and epidemiological studies.
Methods
We conducted a systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles, including studies published until December 2024. A meta-analysis was conducted for outcomes with at least four available effect estimates. Confidence in the body of evidence was evaluated using the Office of Health Assessment and Translation method.
Results
We identified 85 studies investigating various mortality, morbidity and subclinical outcomes. In meta-analyses of single-pollutant models, we found positive associations with natural mortality (hazard ratio 1.06, 95% CI 1.04–1.08) and C-reactive protein (10.14% increase (95% CI −0.51–21.99%) per 10 000 pt·cm−3 increase in long-term exposure to ultrafine particles, with low and inadequate levels of evidence, respectively. The remaining studies revealed overall limited evidence for adverse effects on a wide range of outcomes. Less than half of the studies adjusted for co-pollutants.
Conclusion
The evidence base on long-term health effects of ultrafine particles has increased substantially in the past decade, while the overall evidence for independent effects of long-term ultrafine particle exposure remains inadequate to low. More studies are needed to draw firm conclusions about the independent adverse effects of long-term ultrafine particles on various health end-points, with a special focus on the influence of co-pollutant adjustment.
Altenhilfe
(2025)
Aneignung
(2025)
Die Kriegsbeschädigtenversorgung nach dem Zweiten Weltkrieg als "Soziales Feld" nach Pierre Bourdieu
(2025)
During the coronavirus pandemic, scientists who worked to overcome the outbreak received recognition, but also opposition and even hostility. This article examines how the experience of the pandemic has affected the willingness of scientists to engage with the public. Derived from a comprehensive survey of 4207 scientists at German universities and research institutions, animosity towards scientists during the pandemic has created a sense of insecurity that may cause them to withdraw from the public eye. Depending on the relative strength of two cognitive appraisals, the severity of the threat and the appropriateness of the retreat option, the likelihood of respondents engaging with the public varies significantly.
This study investigates heat transfer enhancement in magneto-nanofluidic systems through the strategic placement of adiabatic blocks in grooved channels. Using CuO–H2O nanofluid in a bottom-heated channel with circular expansion, we examine the complex interactions between forced convection, magnetic fields, and uoyancy effects. Through systematic numerical analysis, we explore the combined influences of Rayleigh, Reynolds, and Hartmann numbers on thermal performance. Our findings reveal significant heat transfer enhancement (up to 137 %) under optimal conditions, particularly with vertical magnetic field orientation at Re = 100 and Ha = 30. The results demonstrate how adiabatic blocks modify flow structures, with larger blocks diminishing vortex intensity while elevated Ra generates secondary vortices that interact with primary circulations. Magnetic field effects show notable dependence on orientation, with vertical fields generally promoting better heat transfer than horizontal configurations. To complement the numerical analysis, we develop a predictive model using Artificial Neural Network (ANN) for Nusselt numbers across various operating conditions, achieving over 99 % accuracy. The integrated computational-ANN approach offers significant advancements in optimizing thermal systems in various areas, ranging from electronics cooling to microfluidic devices.
The BildKlangPoet - a Framework for Designing Mixed Reality Painting Experiences Using Generative AI
(2025)
Smart Services
(2018)
Measurements of the directivity of acoustic sound sources must be interpolated in almost all cases, either for spatial upsampling to higher resolution representations of the data, for spatial resampling to another sampling grid, or for use in simulations of sound propagation. The performance of different interpolation techniques applied to sparsely sampled directivity measurements depends on the sampling grid used but also on the radiation pattern of the sources themselves. Therefore, we evaluated three established approaches for interpolation from a low-resolution sampling grid using high-resolution measurements of a representative sample of musical instruments as a reference. The smallest global error on average occurs for thin plate pseudo-spline interpolation. For interpolation based on spherical harmonics (SH) decomposition, the SH order and the spatial sampling scheme applied have a strong and difficult to predict influence on the quality of the interpolation. The piece-wise linear, spherical triangular interpolation provides almost as good results as the first-order spline approach, albeit with on average 20 times higher computational effort. Therefore, for spatial interpolation of sparsely sampled directivity measurements of musical instruments, the thin plate pseudo-spline method applied to absolute-valued data is recommended and, if necessary, a subsequent modeling of the phase