• search hit 20 of 28
Back to Result List

Computational investigation of hemodynamics in hardshell venous reservoirs: A comparative study

  • Extracorporeal circulation using heart‐lung‐machines is associated with a profound activation of corpuscular and plasmatic components of circulating blood, which can also lead to deleterious events such as systemic inflammatory response and hemolysis. Individual components used to install the extracorporeal circulation have an impact on the level of activation, most predominantly membrane oxygenators and hardshell venous reservoirs as used in extracorporeal systems. The blood flows in two different hardshell reservoirs are computationally investigated. A special emphasis is placed on the prediction of an onset of transition and turbulence generation. Reynolds‐averaged numerical simulations (RANS) based on a transitional turbulence model, as well as large eddy simulations (LES) are applied to achieve an accurate prediction. In the LES analysis, the non‐Newtonian behavior of the blood is considered via the Carreau model. Blood damage potential is quantified applying the Modified Index ofExtracorporeal circulation using heart‐lung‐machines is associated with a profound activation of corpuscular and plasmatic components of circulating blood, which can also lead to deleterious events such as systemic inflammatory response and hemolysis. Individual components used to install the extracorporeal circulation have an impact on the level of activation, most predominantly membrane oxygenators and hardshell venous reservoirs as used in extracorporeal systems. The blood flows in two different hardshell reservoirs are computationally investigated. A special emphasis is placed on the prediction of an onset of transition and turbulence generation. Reynolds‐averaged numerical simulations (RANS) based on a transitional turbulence model, as well as large eddy simulations (LES) are applied to achieve an accurate prediction. In the LES analysis, the non‐Newtonian behavior of the blood is considered via the Carreau model. Blood damage potential is quantified applying the Modified Index of Hemolysis (MIH) based on the predicted flow fields. The results indicate that the flows in both reservoirs remain predominantly laminar. For one of the reservoirs, considerable turbulence generation is observed near the exit site, caused by the specific design for the connection with the drainage tube. This difference causes the MIH of this reservoir to be nearly twice as large as compared to the alternative design. However, a substantial improvement of these performance criteria can be expected by a local geometry modification.show moreshow less

Download full text files

  • This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Export metadata

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Ali Cemal BenimORCiD, Thiemo Frank, Alexander Assmann, Artur Lichtenberg, Payam AkhyariORCiD
open access (DINI-Set):open_access
open access :Hybrid - Subskriptionszeitschrift
agreement:DEAL Wiley
Fachbereich/Einrichtung:Hochschule Düsseldorf / Fachbereich - Maschinenbau und Verfahrenstechnik
Document Type:Article
Year of Completion:2019
Language of Publication:English
Publisher:Wiley
Parent Title (English):Artificial Organs
Volume:44
Issue:4
First Page:411
Last Page:418
URN:urn:nbn:de:hbz:due62-opus-29070
DOI:https://doi.org/10.1111/aor.13593
ISSN:1525-1594
Corresponding Author:Ali Cemal Benim
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 62 Ingenieurwissenschaften / 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
Licence (German):Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
Release Date:2021/04/30
Accept ✔
Diese Webseite verwendet technisch erforderliche Session-Cookies. Durch die weitere Nutzung der Webseite stimmen Sie diesem zu. Unsere Datenschutzerklärung finden Sie hier.