TY - JOUR A1 - Migueles, Jairo H. A1 - Rowlands, Alex V. A1 - Huber, Florian A1 - Sabia, Séverine A1 - van Hees, Vincent T. T1 - GGIR: A Research Community–Driven Open Source R Package for Generating Physical Activity and Sleep Outcomes From Multi-Day Raw Accelerometer Data JF - Journal for the Measurement of Physical Behaviour Y1 - 2019 U6 - https://doi.org/10.1123/jmpb.2018-0063 SN - 2575-6605 VL - 2 IS - 3 SP - 188 EP - 196 PB - Human Kinetics ER - TY - JOUR A1 - Huber, Florian A1 - Käs, Josef A1 - Stuhrmann, Björn T1 - Growing actin networks form lamellipodium and lamellum by self-assembly JF - Biophysical Journal N2 - Many different cell types are able to migrate by formation of a thin actin-based cytoskeletal extension. Recently, it became evident that this extension consists of two distinct substructures, designated lamellipodium and lamellum, which differ significantly in their kinetic and kinematic properties as well as their biochemical composition. We developed a stochastic two-dimensional computer simulation that includes chemical reaction kinetics, G-actin diffusion, and filament transport to investigate the formation of growing actin networks in migrating cells. Model parameters were chosen based on experimental data or theoretical considerations. In this work, we demonstrate the system's ability to form two distinct networks by self-organization. We found a characteristic transition in mean filament length as well as a distinct maximum in depolymerization flux, both within the first 1-2 microm. The separation into two distinct substructures was found to be extremely robust with respect to initial conditions and variation of model parameters. We quantitatively investigated the complex interplay between ADF/cofilin and tropomyosin and propose a plausible mechanism that leads to spatial separation of, respectively, ADF/cofilin- or tropomyosin-dominated compartments. Tropomyosin was found to play an important role in stabilizing the lamellar actin network. Furthermore, the influence of filament severing and annealing on the network properties is explored, and simulation data are compared to existing experimental data. KW - Open Archive Y1 - 2008 UR - http://www.ncbi.nlm.nih.gov/pubmed/18708450 U6 - https://doi.org/10.1529/biophysj.108.134817 SN - 1542-0086 VL - 95 IS - 12 SP - 5508 EP - 5523 PB - Biophysical Society ER - TY - JOUR A1 - Zander, Nils A1 - Kollmannsberger, Stefan A1 - Ruess, Martin A1 - Yosibash, Z. A1 - Rank, Ernst T1 - The Finite Cell Method for linear thermoelasticity JF - Computers & Mathematics with Applications Y1 - 2012 U6 - https://doi.org/10.1016/j.camwa.2012.09.002 SN - 0898-1221 N1 - Open Archiv VL - 64 IS - 11 SP - 3527 EP - 3541 PB - Elsevier ER - TY - JOUR A1 - Guo, Yujie A1 - Ruess, Martin T1 - Weak Dirichlet boundary conditions for trimmed thin isogeometric shells JF - Computers & Mathematics with Applications Y1 - 2015 U6 - https://doi.org/10.1016/j.camwa.2015.06.012 SN - 0898-1221 N1 - Open Archiv VL - 70 IS - 7 SP - 1425 EP - 1440 PB - Elsevier ER - TY - JOUR A1 - Häusler, Alexander T1 - Populismus auf der politischen Bühne JF - iQ konkret KW - Forena Y1 - 2018 UR - https://www.netzwerk-iq.de/fileadmin/Redaktion/Downloads/IQ_Publikationen/IQ_konkret/2018_01_IQ_konkret.pdf N1 - Förderprogramm "Integration durch Qualifizierung (IQ)" IS - 1 ER - TY - JOUR A1 - Tophoven, Silke A1 - Tisch, Anita T1 - Dimensionen prekärer Beschäftigung und Gesundheit im mittleren Lebensalter JF - WSI-Mitteilungen Y1 - 2016 UR - https://doi.org/10.5771/0342-300X-2016-2-105 U6 - https://doi.org/10.5771/0342-300X-2016-2-105 VL - 69 IS - 2 SP - 105 EP - 112 PB - Nomos ER - TY - JOUR A1 - Rauch, Angela A1 - Tophoven, Silke A1 - Eggs, Johannes A1 - Tisch, Anita T1 - Arbeitsbezogene gesundheitsrelevante Faktoren im fortgeschrittenen Erwerbsalter: eine Studie mit neuen Analysemöglichkeiten JF - WSI-Mitteilungen Y1 - 2015 U6 - https://doi.org/10.5771/0342-300X-2015-3-212 VL - 68 IS - 3 SP - 212 EP - 218 PB - Nomos ER - TY - JOUR A1 - Tophoven, Silke T1 - Buchbesprechung: Siegrist, J./Wahrendorf, M. (Hrsg.) (2016): Work Stress and Health in a Globalized Economy. The Model of Effort-Reward Imbalance. Cham: Springer International Publishing JF - WSI-Mitteilungen Y1 - 2017 UR - https://www.nomos-elibrary.de/10.5771/0342-300X-2017-3-224/buchbesprechung-jahrgang-70-2017-heft-3 VL - 70 IS - 3 PB - Nomos ER - TY - JOUR A1 - Girod, Kai A1 - Breitkreuz, Klaas A1 - Gerstner, Andrea A1 - Marzi, Thomas A1 - Schulzke, Tim A1 - Kaluza, Stefan T1 - Close‐to‐Practice Investigations of Heterogeneously Catalyzed Syngas Conversions in Slurry and Fixed‐Bed Reactor Systems JF - Chemie Ingenieur Technik Y1 - 2018 U6 - https://doi.org/10.1002/cite.201700143 SN - 1522-2640 VL - 90 IS - 5 SP - 690 EP - 695 PB - Wiley ER - TY - JOUR A1 - Junge Puring, Kai A1 - Piontek, Stefan A1 - Smialkowski, Mathias A1 - Burfeind, Jens A1 - Kaluza, Stefan A1 - Doetsch, Christian A1 - Apfel, Ulf-Peter T1 - Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications JF - Journal of visualized experiments : JoVE N2 - The rock material pentlandite with the composition Fe4.5Ni4.5S8 was synthesized via high temperature synthesis from the elements. The structure and composition of the material was characterized via powder X-ray diffraction (PXRD), Mössbauer spectroscopy (MB), scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and energy dispersive X-ray spectroscopy (EDX). Two preparation methods of pentlandite bulk electrodes are presented. In the first approach a piece of synthetic pentlandite rock is directly contacted via a wire ferrule. The second approach utilizes pentlandite pellets, pressed from finely ground powder, which is immobilized in a Teflon casing. Both electrodes, whilst being prepared by an additive-free method, reveal high durability during electrocatalytic conversions in comparison to common drop-coating methods. We herein showcase the striking performance of such electrodes to accomplish the hydrogen evolution reaction (HER) and present a standardized method to evaluate the electrocatalytic performance by electrochemical and gas chromatographic methods. Furthermore, we report stability tests via potentiostatic methods at an overpotential of 0.6 V to explore the material limitations of the electrodes during electrolysis under industrial relevant conditions. Y1 - 2017 UR - http://www.ncbi.nlm.nih.gov/pubmed/28671654 U6 - https://doi.org/10.3791/56087 SN - 1940-087X IS - 124 PB - JoVE ER -