TY - CHAP A1 - Glowatz, Christoph A1 - Haufs-Brusberg, Peter A1 - Schmidt, Holger ED - Schulz, Thomas T1 - Unternehmensorganisation und Informationssicherheit: Einführung und Grundlagen (Kap. F1) T2 - Cybersicherheit für vernetzte Anwendungen in der Industrie 4.0 Y1 - 2019 SN - 978-3834334244 SP - 315 EP - 334 PB - Vogel Communications Group CY - Würzburg ER - TY - JOUR A1 - Migueles, Jairo H. A1 - Rowlands, Alex V. A1 - Huber, Florian A1 - Sabia, Séverine A1 - van Hees, Vincent T. T1 - GGIR: A Research Community–Driven Open Source R Package for Generating Physical Activity and Sleep Outcomes From Multi-Day Raw Accelerometer Data JF - Journal for the Measurement of Physical Behaviour Y1 - 2019 U6 - https://doi.org/10.1123/jmpb.2018-0063 SN - 2575-6605 VL - 2 IS - 3 SP - 188 EP - 196 PB - Human Kinetics ER - TY - JOUR A1 - Huber, Florian A1 - Boire, Adeline A1 - López, Magdalena Preciado A1 - Koenderink, Gijsje H. T1 - Cytoskeletal crosstalk: when three different personalities team up JF - Current Opinion in Cell Biology Y1 - 2015 U6 - https://doi.org/10.1016/j.ceb.2014.10.005 SN - 1879-0410 VL - 32 SP - 39 EP - 47 PB - Elsevier ER - TY - JOUR A1 - Huber, Florian A1 - Käs, Josef T1 - Self-regulative organization of the cytoskeleton JF - Cytoskeleton N2 - Despite its impressive complexity the cytoskeleton succeeds to persistently organize itself and thus the cells' interior. In contrast to classical man-made machines, much of the cellular organization originates from inherent self-assembly and self-organization allowing a high degree of autonomy for various functional units. Recent experimental and theoretical studies revealed numerous examples of cytoskeleton components that arrange and organize in a self-regulative way. In the present review we want to shortly summarize some of the principle mechanisms that are able to inherently trigger and regulate the cytoskeleton organization. Although taken individually most of these regulative principles are rather simple with intuitively predictable consequences, combinations of two or more of these mechanisms can quickly give rise to very complex, unexpected behavior and might even be able to explain the formation of different functional units out of a common pool of available building blocks. Y1 - 2011 UR - http://www.ncbi.nlm.nih.gov/pubmed/21438165 U6 - https://doi.org/10.1002/cm.20509 SN - 1949-3592 N1 - Acknowledgment We would like to thank Dan Strehle for critical reading ofthis manuscript. This work was funded by the Leipzig School of Natural Sciences ‘‘BuildMoNa’’ as well as bythe Sa¨chsische Aufbaubank project number 13403 VL - 68 IS - 5 SP - 259 EP - 265 PB - Wiley ER - TY - JOUR A1 - Huber, Florian A1 - Käs, Josef A1 - Stuhrmann, Björn T1 - Growing actin networks form lamellipodium and lamellum by self-assembly JF - Biophysical Journal N2 - Many different cell types are able to migrate by formation of a thin actin-based cytoskeletal extension. Recently, it became evident that this extension consists of two distinct substructures, designated lamellipodium and lamellum, which differ significantly in their kinetic and kinematic properties as well as their biochemical composition. We developed a stochastic two-dimensional computer simulation that includes chemical reaction kinetics, G-actin diffusion, and filament transport to investigate the formation of growing actin networks in migrating cells. Model parameters were chosen based on experimental data or theoretical considerations. In this work, we demonstrate the system's ability to form two distinct networks by self-organization. We found a characteristic transition in mean filament length as well as a distinct maximum in depolymerization flux, both within the first 1-2 microm. The separation into two distinct substructures was found to be extremely robust with respect to initial conditions and variation of model parameters. We quantitatively investigated the complex interplay between ADF/cofilin and tropomyosin and propose a plausible mechanism that leads to spatial separation of, respectively, ADF/cofilin- or tropomyosin-dominated compartments. Tropomyosin was found to play an important role in stabilizing the lamellar actin network. Furthermore, the influence of filament severing and annealing on the network properties is explored, and simulation data are compared to existing experimental data. KW - Open Archive Y1 - 2008 UR - http://www.ncbi.nlm.nih.gov/pubmed/18708450 U6 - https://doi.org/10.1529/biophysj.108.134817 SN - 1542-0086 VL - 95 IS - 12 SP - 5508 EP - 5523 PB - Biophysical Society ER - TY - JOUR A1 - Huber, Florian A1 - Strehle, Dan A1 - Kaes, Josef T1 - Counterion-induced formation of regular actin bundle networks JF - Soft Matter Y1 - 2012 SN - 1744-6848 VL - 8 IS - 4 SP - 931 EP - 936 PB - Royal Society of Chemistry ER - TY - JOUR A1 - Preciado López, Magdalena A1 - Huber, Florian A1 - Grigoriev, Ilya A1 - Steinmetz, Michel O. A1 - Akhmanova, Anna A1 - Dogterom, Marileen A1 - Koenderink, Gijsje H. T1 - In vitro reconstitution of dynamic microtubules interacting with actin filament networks JF - Methods in Enzymology Y1 - 2014 U6 - https://doi.org/10.1016/B978-0-12-397924-7.00017-0 SN - 1557-7988 VL - 540 SP - 301 EP - 320 PB - Elsevier ER - TY - JOUR A1 - Siccardi, Stefano A1 - Adamatzky, Andrew A1 - Tuszyński, Jack A1 - Huber, Florian A1 - Schnauß, Jörg T1 - Actin networks voltage circuits JF - Physical Review E Y1 - 2020 U6 - https://doi.org/10.1103/PhysRevE.101.052314 SN - 2470-0053 VL - 101 IS - 5-1 PB - American Physical Society (APS) ER - TY - JOUR A1 - Smith, David A1 - Gentry, Brian A1 - Stuhrmann, Björn A1 - Huber, Florian A1 - Strehle, D. A.N. A1 - Brunner, Claudia A1 - Koch, Daniel A1 - Steinbeck, Matthias A1 - Betz, Timo A1 - Käs, Josef A. T1 - The cytoskeleton: An active polymer-based scaffold JF - Biophysical Reviews and Letters Y1 - 2009 U6 - https://doi.org/10.1142/S1793048009000983 SN - 1793-7035 VL - 04 SP - 179 EP - 208 ER - TY - GEN A1 - Jarosch, Monika A1 - Herder, Jens A1 - Langmann, Mathias T1 - Entwicklung einer AR-Applikation zur kosteneffektiven volumetrischen Erfassung von Baugruben T2 - gis.Science N2 - Die volumetrische Erfassung von Aushüben auf Baustellen ist ein kostenrelevanter Faktor und wird auch heute im täglichen Baustellenbetrieb oft noch in manueller Detailarbeit durchgeführt. Kostengünstige Sensoren zur Tiefenerfassung ermöglichen die halbautomatische Erfassung von Baugruben. Augmented Reality (AR) kann für diesen Prozess das nötige Feedback liefern. Vorgestellt wird ein Prototyp, bestehend aus einem Tablet mit integrierter Kamera und einem Lidar-Scanner. Es wird die Erfassung des Volumens bezüglich Nutzbarkeit und Genauigkeit mit Einsatz von AR getestet und evaluiert. Zur Bestimmung des Volumens wird unter Verwendung von Strahlen mit Unterstützung einer Grafik-Engine ein Algorithmus entwickelt. Der Algorithmus ist robust gegen nicht vollständig geschlossene Volumen. Die Bedienung, Überprüfung und Visualisierung findet durch praktischen Einsatz von AR statt. KW - Volumenbestimmung KW - Augmented Reality KW - Baustelle KW - LIDAR KW - VSVR Y1 - 2022 UR - https://gispoint.de/artikelarchiv/gis/2022/gisscience-ausgabe-22022/7427-entwicklung-einer-ar-applikation-zur-kosteneffektiven-volumetrischen-erfassung-von-baugruben.html SN - 2698-4571 N1 - Der Artikel ist als PDF beim Verlag herunterladbar. Dieses wurde nach 3 Monaten freigeschaltet. Vorher war ein Abonnement notwendig. VL - 2022 IS - 2 SP - 75 EP - 83 PB - Wichmann ER -