@incollection{SchmidtHateburHeisel2018, author = {Schmidt, Holger and Hatebur, Denis and Heisel, Maritta}, title = {Developing Secure Software Using UML Patterns}, series = {Intelligent systems: Concepts, methodologies, tools, and applications}, booktitle = {Intelligent systems: Concepts, methodologies, tools, and applications}, publisher = {IGI Global}, address = {Hershey, Pennsylvania}, organization = {Management Association, Information Resources}, isbn = {9781522556435}, doi = {10.4018/978-1-5225-5643-5.ch022}, pages = {551 -- 592}, year = {2018}, language = {en} } @article{DeckertSchomaker2022, author = {Deckert, Carsten and Schomaker, Rahel M.}, title = {Cultural tightness-looseness and national innovativeness: impacts of tolerance and diversity of opinion}, series = {Journal of Innovation and Entrepreneurship}, volume = {11}, journal = {Journal of Innovation and Entrepreneurship}, publisher = {Springer Nature}, issn = {2192-5372}, doi = {10.1186/s13731-022-00219-2}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-36515}, pages = {1 -- 19}, year = {2022}, abstract = {The links between innovativeness as a driver of economic performance, and the determinants of innovativeness have been investigated by management scholars and economists for decades, focusing mostly on "hard factors" as investment in research and development, or education. Focusing on a relatively neglected, but in times of globalization even more important aspect, the infuence of cultural characteristics on innovativeness, we apply diferent econometric models to test for links between cultural tightness and looseness on the one hand, and national innovativeness on the other hand. We fnd that cultural tightness—in the sense of homogenous and intolerant societies—has a negative link to national innovativeness, while cultural looseness—in the sense of tolerant and diverse societies—displays a positive link to national innovativeness.}, subject = {Innovation}, language = {en} } @inproceedings{KornmesserBraunBeushausen2001, author = {Kornmesser, Christoph and Braun, Alexander and Beushausen, Volker}, title = {Applicability of different fluorescent dyes for 2D temperature measurements in dense sprays using planar laser induced fluorescence}, series = {Proceedings of the 17th Annual Conference on Liquid Atomization and Spray Systems, 02.06.2001, Z{\"u}rich}, booktitle = {Proceedings of the 17th Annual Conference on Liquid Atomization and Spray Systems, 02.06.2001, Z{\"u}rich}, publisher = {ETH Z{\"u}rich}, address = {Z{\"u}rich}, isbn = {3952224413}, pages = {554 -- 559}, year = {2001}, language = {en} } @inproceedings{MuellerLehmannBraun2020, author = {Mueller, Patrick and Lehmann, Matthias and Braun, Alexander}, title = {Simulating tests to test simulation}, series = {IS\&T International Symposium on Electronic Imaging 2020: Autonomous Vehicles and Machines, 26 January 2020 — 30 January 2020, Burlingame, CA, USA}, volume = {2020}, booktitle = {IS\&T International Symposium on Electronic Imaging 2020: Autonomous Vehicles and Machines, 26 January 2020 — 30 January 2020, Burlingame, CA, USA}, number = {16}, publisher = {Society for Imaging Science and Technology}, doi = {10.2352/ISSN.2470-1173.2020.16.AVM-149}, year = {2020}, language = {en} } @article{MuellerBrummelBraun2021, author = {M{\"u}ller, Patrick and Brummel, Mattis and Braun, Alexander}, title = {Spatial recall index for machine learning algorithms}, series = {London Imaging Meeting}, volume = {2021}, journal = {London Imaging Meeting}, number = {1}, publisher = {Society for Imaging Science and Technology}, isbn = {0-89208-346-6}, doi = {10.2352/issn.2694-118X.2021.LIM-58}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-35657}, pages = {58 -- 62}, year = {2021}, abstract = {We present a novel metric Spatial Recall Index to assess the performance of machine-learning (ML) algorithms for automotive applications, focusing on where in the image which performance occurs. Typical metrics like intersection-over-union (IoU), precisionrecallcurves or average precision (AP) quantify the performance over a whole database of images, neglecting spatial performance variations. But as the optics of camera systems are spatially variable over the field of view, the performance of ML-based algorithms is also a function of space, which we show in simulation: A realistic objective lens based on a Cooke-triplet that exhibits typical optical aberrations like astigmatism and chromatic aberration, all variable over field, is modeled. The model is then applied to a subset of the BDD100k dataset with spatially-varying kernels. We then quantify local changes in the performance of the pre-trained Mask R-CNN algorithm. Our examples demonstrate the spatial dependence of the performance of ML-based algorithms from the optical quality over field, highlighting the need to take the spatial dimension into account when training ML-based algorithms, especially when looking forward to autonomous driving applications.}, language = {en} } @article{TsengMoslehMannanetal.2021, author = {Tseng, Ethan and Mosleh, Ali and Mannan, Fahim and St-Arnaud, Karl and Sharma, Avinash and Peng, Yifan and Braun, Alexander and Nowrouzezahrai, Derek and Lalonde, Jean-Fran{\c{c}}ois and Heide, Felix}, title = {Differentiable Compound Optics and Processing Pipeline Optimization for End-to-end Camera Design}, series = {ACM Transactions on Graphics}, volume = {40}, journal = {ACM Transactions on Graphics}, number = {2}, publisher = {Association for Computing Machinery}, address = {New York, NY, USA}, issn = {1557-7368}, doi = {10.1145/3446791}, pages = {1 -- 19}, year = {2021}, abstract = {Most modern commodity imaging systems we use directly for photography--or indirectly rely on for downstream applications--employ optical systems of multiple lenses that must balance deviations from perfect optics, manufacturing constraints, tolerances, cost, and footprint. Although optical designs often have complex interactions with downstream image processing or analysis tasks, today's compound optics are designed in isolation from these interactions. Existing optical design tools aim to minimize optical aberrations, such as deviations from Gauss' linear model of optics, instead of application-specific losses, precluding joint optimization with hardware image signal processing (ISP) and highly parameterized neural network processing. In this article, we propose an optimization method for compound optics that lifts these limitations. We optimize entire lens systems jointly with hardware and software image processing pipelines, downstream neural network processing, and application-specific end-to-end losses. To this end, we propose a learned, differentiable forward model for compound optics and an alternating proximal optimization method that handles function compositions with highly varying parameter dimensions for optics, hardware ISP, and neural nets. Our method integrates seamlessly atop existing optical design tools, such as Zemax. We can thus assess our method across many camera system designs and end-to-end applications. We validate our approach in an automotive camera optics setting--together with hardware ISP post processing and detection--outperforming classical optics designs for automotive object detection and traffic light state detection. For human viewing tasks, we optimize optics and processing pipelines for dynamic outdoor scenarios and dynamic low-light imaging. We outperform existing compartmentalized design or fine-tuning methods qualitatively and quantitatively, across all domain-specific applications tested.}, language = {en} } @article{WittpahlDeeganBlacketal.2021, author = {Wittpahl, Christian and Deegan, Brian and Black, Bob and Braun, Alexander}, title = {An analytic-numerical image flicker study to test novel flicker metrics}, series = {Electronic Imaging: Society for Imaging Science and Technology}, journal = {Electronic Imaging: Society for Imaging Science and Technology}, number = {17}, publisher = {Society for Imaging Science and Technology}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2021.17.AVM-183}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-35671}, pages = {1 -- 8}, year = {2021}, language = {en} } @article{WittpahlZakourLehmannetal.2018, author = {Wittpahl, Christian and Zakour, Hatem Ben and Lehmann, Matthias and Braun, Alexander}, title = {Realistic Image Degradation with Measured PSF}, series = {Electronic Imaging, Autonomous Vehicles and Machines 2018}, journal = {Electronic Imaging, Autonomous Vehicles and Machines 2018}, number = {17}, publisher = {Society for Imaging Science and Technology}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2018.17.AVM-149}, pages = {149}, year = {2018}, language = {en} } @phdthesis{Braun2007, author = {Braun, Alexander}, title = {Addressing Single Yb+ Ions: A new scheme for quantum computing in linear ion traps}, publisher = {Cuvillier Verlag}, address = {G{\"o}ttingen}, isbn = {978-3-86727-276-6}, pages = {169}, year = {2007}, language = {en} } @inproceedings{BalzerHannemannWunderlichetal.2005, author = {Balzer, Christoph and Hannemann, Th. and Wunderlich, Chr. and Braun, Alexander and Ettler, M. and Paape, Chr. and Neuhauser, W.}, title = {Efficient photoionisation, preparation and coherent manipulation of trapped /sup 171/Yb/sup +/-ions}, series = {EQEC '05. European Quantum Electronics Conference, 12-17 June 2005, Munich}, booktitle = {EQEC '05. European Quantum Electronics Conference, 12-17 June 2005, Munich}, publisher = {IEEE}, isbn = {0-7803-8973-5}, doi = {10.1109/EQEC.2005.1567474}, pages = {308}, year = {2005}, language = {en} } @incollection{VoigtUnterfraunerStelzer2017, author = {Voigt, Christian and Unterfrauner, Elisabeth and Stelzer, Roland}, title = {Diversity in FabLabs: Culture, Role Models and the Gendering of Making}, series = {Internet Science}, volume = {Lecture Notes in Computer Science, 10673}, booktitle = {Internet Science}, editor = {Kompatsiaris, Ioannis and Cave, Jonathan and Satsiou, Anna and Carle, Georg and Passani, Antonella and Kontopoulos, Efstratios and Diplaris, Sotiris and McMillan, Donald}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-70283-4}, doi = {10.1007/978-3-319-70284-1_5}, pages = {52 -- 68}, year = {2017}, language = {en} } @inproceedings{VoigtUnterfraunerAslanetal.2019, author = {Voigt, Christian and Unterfrauner, E. and Aslan, Tamer and Hofer, Margit}, title = {Design Thinking with Children}, series = {Proceedings of FabLearn 2019, 09.03.-10.03.2019, New York}, booktitle = {Proceedings of FabLearn 2019, 09.03.-10.03.2019, New York}, editor = {Blikstein, Paulo and Holbert, Nathan}, publisher = {ACM}, address = {New York}, isbn = {9781450362443}, doi = {10.1145/3311890.3311912}, pages = {144 -- 147}, year = {2019}, language = {en} } @inproceedings{BeckerLippelZielke2019, author = {Becker, Martin and Lippel, Jens and Zielke, Thomas}, title = {Gradient Descent Analysis: On Visualizing the Training of Deep Neural Networks}, series = {VISIGRAPP 2019: Proceedings of the 14th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications : Prague, Czech Republic, February 25-27, 2019}, volume = {Volume: 3}, booktitle = {VISIGRAPP 2019: Proceedings of the 14th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications : Prague, Czech Republic, February 25-27, 2019}, publisher = {INSTICC}, isbn = {978-989-758-354-4}, doi = {10.5220/0007583403380345}, pages = {338 -- 345}, year = {2019}, language = {en} } @inproceedings{BeckerLippelZielke2021, author = {Becker, Martin and Lippel, Jens and Zielke, Thomas}, title = {Dimensionality Reduction for Data Visualization and Linear Classification, and the Trade-off between Robustness and Classification Accuracy}, series = {Proceedings of ICPR 2020: 25th International Conference on Pattern Recognition, 10-15 January 2021, Milan}, booktitle = {Proceedings of ICPR 2020: 25th International Conference on Pattern Recognition, 10-15 January 2021, Milan}, editor = {Vezzani, Roberto}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-72818-808-9}, doi = {10.1109/ICPR48806.2021.9412865}, pages = {6478 -- 6485}, year = {2021}, language = {en} } @inproceedings{LippelBeckerZielke2019, author = {Lippel, Jens and Becker, Martin and Zielke, Thomas}, title = {Modeling Dynamic Processes with Deep Neural Networks: A Case Study with a Gas-fired Absorption Heat Pump}, series = {SIMULTECH 2019: Proceedings of the 9th International Conference on Simulation and Modeling Methodologies, Technologies and Applications : Prague, Czech RepublicJuly 29-31, 2019}, booktitle = {SIMULTECH 2019: Proceedings of the 9th International Conference on Simulation and Modeling Methodologies, Technologies and Applications : Prague, Czech RepublicJuly 29-31, 2019}, editor = {Obaidat, Mohammad S. and {\"O}ren, Tuncer and Szczerbicka, Helena}, publisher = {INSTICC}, isbn = {978-989-758-381-0}, doi = {10.5220/0007932903170326}, pages = {317 -- 326}, year = {2019}, language = {en} } @inproceedings{ZielkeBernstCrombachetal.2018, author = {Zielke, Thomas and Bernst, Irina and Crombach, Tobias and Becker, Martin and Lippel, Jens}, title = {WHAT CAN BE LEARNED BY GRADING ANALYTICS?}, series = {INTED 2018: 12th International Technology, Education and Development Conference : 5-7 March, 2018, Valencia (Spain) : conference proceedings}, volume = {12th International Technology, Education and Development Conference}, booktitle = {INTED 2018: 12th International Technology, Education and Development Conference : 5-7 March, 2018, Valencia (Spain) : conference proceedings}, editor = {G{\´o}mez Chova, Luis and L{\´o}pez Mart{\´i}nez, A. and Candel Torres, I.}, publisher = {IATED Academy}, address = {Valencia, Spain}, isbn = {978-84-697-9480-7}, doi = {10.21125/inted.2018.0593}, pages = {3097 -- 3106}, year = {2018}, language = {en} } @inproceedings{FaberAnthrakidisLanzetal.2011, author = {Faber, Christian and Anthrakidis, Anette and Lanz, Marco and Rusack, Markus and Weis, Fabian and Adam, Mario and Schramm, Sebastian}, title = {Barriers to solar process heat applications,}, series = {SWC 2011: ISES Solar World Congress, 28 August - 2 September 2011, Kassel, Germany}, booktitle = {SWC 2011: ISES Solar World Congress, 28 August - 2 September 2011, Kassel, Germany}, address = {Kassel}, pages = {1326 -- 1334}, year = {2011}, language = {en} } @incollection{LohmannIlleAdam2013, author = {Lohmann, Sandra and Ille, Fabian and Adam, Mario}, title = {Solar cooling in a hardware-in-the-loop test and pilot plant. Postersession A1}, series = {5th International Conference Solar Air-Conditioning, 25.-27.09.2013, Bad Krozingen}, booktitle = {5th International Conference Solar Air-Conditioning, 25.-27.09.2013, Bad Krozingen}, organization = {Ostbayerisches Technologie-Transfer-Institut e. V.}, isbn = {978-3-943891-21-8}, year = {2013}, language = {en} } @article{EckhardtKaletkaPelkaetal.2021, author = {Eckhardt, Jennifer and Kaletka, Christoph and Pelka, Bastian and Unterfrauner, Elisabeth and Voigt, Christian and Zirngiebl, Marthe}, title = {Gender in the making: An empirical approach to understand gender relations in the maker movement}, series = {International Journal of Human-Computer Studies}, volume = {145}, journal = {International Journal of Human-Computer Studies}, number = {102548}, publisher = {Elsevier}, issn = {1095-9300}, doi = {10.1016/j.ijhcs.2020.102548}, year = {2021}, language = {en} } @inproceedings{KahnMonteroVoigt2018, author = {Kahn, Ken and Montero, Calkin Suero and Voigt, Christian}, title = {STEAM learning in formal and informal settings via craft and maker projects}, series = {Proceedings of the 17th ACM Conference on Interaction Design and Children, 19.06.-22.06.2018, Trondheim}, booktitle = {Proceedings of the 17th ACM Conference on Interaction Design and Children, 19.06.-22.06.2018, Trondheim}, editor = {Giannakos, Michail N. and Jaccheri, Letizia and Divitini, Monica}, publisher = {ACM}, address = {New York}, isbn = {9781450351522}, doi = {10.1145/3202185.3205869}, pages = {728 -- 733}, year = {2018}, language = {en} } @article{MillardSorivelleDeljaninetal.2018, author = {Millard, Jeremy and Sorivelle, Marie and Deljanin, Sarah and Unterfrauner, Elisabeth and Voigt, Christian}, title = {Is the Maker Movement Contributing to Sustainability?}, series = {Sustainability}, volume = {10}, journal = {Sustainability}, number = {7}, publisher = {MDPI}, issn = {2071-1050}, doi = {10.3390/su10072212}, pages = {2212}, year = {2018}, language = {en} } @article{SeebacherVanaVoigtetal.2021, author = {Seebacher, Lisa M. and Vana, Irina and Voigt, Christian and Tschank, Juliet}, title = {Is Science for Everyone? Exploring Intersectional Inequalities in Connecting With Science}, series = {Frontiers in Education}, volume = {6}, journal = {Frontiers in Education}, publisher = {Frontiers}, issn = {2504-284X}, doi = {10.3389/feduc.2021.673850}, year = {2021}, language = {en} } @article{UnterfraunerVoigt2017, author = {Unterfrauner, Elisabeth and Voigt, Christian}, title = {Makers' ambitions to do socially valuable things}, series = {The Design Journal}, volume = {20}, journal = {The Design Journal}, number = {sup1}, publisher = {Taylor \& Francis}, issn = {1756-3062}, doi = {10.1080/14606925.2017.1352835}, pages = {3317 -- 3325}, year = {2017}, language = {en} } @incollection{UnterfraunerVoigtSchrammeletal.2018, author = {Unterfrauner, Elisabeth and Voigt, Christian and Schrammel, Maria and Menichinelli, Massimo}, title = {The Maker Movement and the Disruption of the Producer-Consumer Relation}, series = {Internet Science}, volume = {Lecture Notes in Computer Science: 10750}, booktitle = {Internet Science}, editor = {Diplaris, Sotiris and Satsiou, Anna and F{\o}lstad, Asbj{\o}rn and Vafopoulos, Michail and Vilarinho, Thomas}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-77546-3}, doi = {10.1007/978-3-319-77547-0_9}, pages = {113 -- 125}, year = {2018}, language = {en} } @incollection{UnterfraunerVoigtHofer2019, author = {Unterfrauner, Elisabeth and Voigt, Christian and Hofer, Margit}, title = {Participative evaluation with children in educational maker projects}, series = {Proceedings of the 9th International Conference on Communities \& Technologies - Transforming Communities, 03.06.-07.06.2019, Vienna}, booktitle = {Proceedings of the 9th International Conference on Communities \& Technologies - Transforming Communities, 03.06.-07.06.2019, Vienna}, editor = {Tellioglu, Hilda and Teli, Maurizio and Nathan, Lisa}, publisher = {ACM}, address = {New York,}, isbn = {9781450371629}, doi = {10.1145/3328320.3328372}, pages = {194 -- 197}, year = {2019}, language = {en} } @inproceedings{UnterfraunerVoigtSchoen2019, author = {Unterfrauner, Elisabeth and Voigt, Christian and Sch{\"o}n, Sandra}, title = {Towards a Model of Early Entrepreneurial Education: Appreciation, Facilitation and Evaluation}, series = {Methodologies and Intelligent Systems for Technology Enhanced Learning, 8th International Conference}, volume = {Advances in Intelligent Systems and Computing: 804}, booktitle = {Methodologies and Intelligent Systems for Technology Enhanced Learning, 8th International Conference}, editor = {Di Mascio, Tania and Vittorini, Pierpaolo and Gennari, Rosella and de La Prieta, Fernando and Rodr{\´i}guez, Sara and Temperini, Marco and Azambuja Silveira, Ricardo and Popescu, Elvira and Lancia, Loreto}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-98871-9}, doi = {10.1007/978-3-319-98872-6_17}, pages = {139 -- 146}, year = {2019}, language = {en} } @article{UnterfraunerVoigtHofer2021, author = {Unterfrauner, Elisabeth and Voigt, Christian and Hofer, Margit}, title = {The effect of maker and entrepreneurial education on self-efficacy and creativity}, series = {Entrepreneurship Education}, volume = {4}, journal = {Entrepreneurship Education}, number = {4}, publisher = {Springer Nature}, issn = {2520-8152}, doi = {10.1007/s41959-021-00060-w}, pages = {403 -- 424}, year = {2021}, language = {en} } @inproceedings{Voigt2018, author = {Voigt, Christian}, title = {Not Every Remix is an Innovation}, series = {Proceedings of the 10th ACM Conference on Web Science, 27.05.-30.05.2018, Amsterdam}, booktitle = {Proceedings of the 10th ACM Conference on Web Science, 27.05.-30.05.2018, Amsterdam}, editor = {Akkermans, Hans and Fontaine, Kathy and Vermeulen, Ivar and Houben, Geert-Jan and Weber, Matthew S.}, publisher = {ACM}, address = {New York}, isbn = {9781450355636}, doi = {10.1145/3201064.3201070}, pages = {153 -- 161}, year = {2018}, language = {en} } @inproceedings{VoigtDobnerNeuschmid2015, author = {Voigt, Christian and Dobner, Susanne and Neuschmid, Julia}, title = {Data-driven and value sensitive urban decision making}, series = {eChallenges e-2015 Conference, 25.11. - 27.11.2015, Vilnius}, booktitle = {eChallenges e-2015 Conference, 25.11. - 27.11.2015, Vilnius}, publisher = {IEEE}, isbn = {978-1-9058-2453-3}, doi = {10.1109/echallenges.2015.7441077}, pages = {1 -- 9}, year = {2015}, language = {en} } @incollection{VoigtDobnerFerrietal.2016, author = {Voigt, Christian and Dobner, Susanne and Ferri, Mireia and Hahmann, Stefan and Gareis, Karsten}, title = {Community Engagement Strategies for Crowdsourcing Accessibility Information}, series = {Computers Helping People with Special Needs}, volume = {Lecture Notes in Computer Science: 9759}, booktitle = {Computers Helping People with Special Needs}, editor = {Miesenberger, Klaus and B{\"u}hler, Christian and Penaz, Petr}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-41266-5}, doi = {10.1007/978-3-319-41267-2_35}, pages = {257 -- 264}, year = {2016}, language = {en} } @incollection{VoigtKieslingerSchaefer2017, author = {Voigt, Christian and Kieslinger, Barbara and Sch{\"a}fer, Teresa}, title = {User Experiences Around Sentiment Analyses, Facilitating Workplace Learning}, series = {Social Computing and Social Media. Applications and Analytics}, volume = {Lecture Notes in Computer Science: 10283}, booktitle = {Social Computing and Social Media. Applications and Analytics}, editor = {Meiselwitz, Gabriele}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-58561-1}, doi = {10.1007/978-3-319-58562-8_24}, pages = {312 -- 324}, year = {2017}, language = {en} } @incollection{VoigtMairUnterfrauner2018, author = {Voigt, Christian and Mair, Sebastian and Unterfrauner, Elisabeth}, title = {Hacking the Knowledge of Maker Communities in Support of 21st Century Education}, series = {Internet Science}, volume = {Lecture Notes in Computer Science: 11193}, booktitle = {Internet Science}, editor = {Bodrunova, Svetlana S.}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-030-01436-0}, doi = {10.1007/978-3-030-01437-7_22}, pages = {286 -- 299}, year = {2018}, language = {en} } @inproceedings{VoigtMisuracaKucseraetal.2016, author = {Voigt, Christian and Misuraca, Gianluca and Kucsera, Csaba and Lipparini, Fiorenza}, title = {ICT-enabled Social Innovations in Social Services: Mapping the Evidence}, series = {2016 Conference for E-Democracy and Open Government (CeDEM), 18.05.2016 - 20.05.2016, Krems, Austria}, booktitle = {2016 Conference for E-Democracy and Open Government (CeDEM), 18.05.2016 - 20.05.2016, Krems, Austria}, publisher = {IEEE}, isbn = {978-1-5090-1042-4}, doi = {10.1109/cedem.2016.15}, pages = {105 -- 114}, year = {2016}, language = {en} } @incollection{VoigtMonteroMenichinelli2016, author = {Voigt, Christian and Montero, Calkin Suero and Menichinelli, Massimo}, title = {An Empirically Informed Taxonomy for the Maker Movement}, series = {Internet Science}, volume = {Lecture Notes in Computer Science, 9934}, booktitle = {Internet Science}, editor = {Bagnoli, Franco and Satsiou, Anna and Stavrakakis, Ioannis and Nesi, Paolo and Pacini, Giovanna and Welp, Yanina and Tiropanis, Thanassis and DiFranzo, Dominic}, publisher = {Springer International Publishing}, address = {Cham}, isbn = {978-3-319-45981-3}, doi = {10.1007/978-3-319-45982-0_17}, pages = {189 -- 204}, year = {2016}, language = {en} } @article{VoigtSwatman2004, author = {Voigt, Christian and Swatman, Paula}, title = {Contextual e-learning evaluation: A preliminary framework}, series = {Journal of Educational Media}, volume = {29}, journal = {Journal of Educational Media}, number = {3}, publisher = {Taylor \& Francis}, issn = {1469-9443}, doi = {10.1080/1358165042000283057}, pages = {175 -- 187}, year = {2004}, language = {en} } @inproceedings{VoigtSwatman2006, author = {Voigt, Christian and Swatman, Paula}, title = {Online Case Discussions: Tensions in Activity Systems}, series = {Sixth IEEE International Conference on Advanced Learning Technologies (ICALT'06), 05-07 July 2006, Kerkrade, The Netherlands}, booktitle = {Sixth IEEE International Conference on Advanced Learning Technologies (ICALT'06), 05-07 July 2006, Kerkrade, The Netherlands}, publisher = {IEEE}, isbn = {0-7695-2632-2}, doi = {10.1109/icalt.2006.1652550}, pages = {748 -- 750}, year = {2006}, language = {en} } @inproceedings{BackesFaberAnthrakidisetal.2008, author = {Backes, Klaus and Faber, Christian and Anthrakidis, Anette and Ille, Fabian and Adam, Mario and Schramm, Sebastian}, title = {A small scale Combined Cooling, Heating and Power System}, series = {World Renewable Energy Congress X and Exhibition, 19-25.07.2008, Glasgow}, booktitle = {World Renewable Energy Congress X and Exhibition, 19-25.07.2008, Glasgow}, editor = {WREN,}, address = {Glasgow}, year = {2008}, language = {en} } @article{MiguelesRowlandsHuberetal.2019, author = {Migueles, Jairo H. and Rowlands, Alex V. and Huber, Florian and Sabia, S{\´e}verine and van Hees, Vincent T.}, title = {GGIR: A Research Community-Driven Open Source R Package for Generating Physical Activity and Sleep Outcomes From Multi-Day Raw Accelerometer Data}, series = {Journal for the Measurement of Physical Behaviour}, volume = {2}, journal = {Journal for the Measurement of Physical Behaviour}, number = {3}, publisher = {Human Kinetics}, issn = {2575-6605}, doi = {10.1123/jmpb.2018-0063}, pages = {188 -- 196}, year = {2019}, language = {en} } @article{SchornVerhoevenRidderetal.2021, author = {Schorn, Michelle A. and Verhoeven, Stefan and Ridder, Lars and Huber, Florian and Acharya, Deepa D. and Aksenov, Alexander A. and Aleti, Gajender and Moghaddam, Jamshid Amiri and Aron, Allegra T. and Aziz, Saefuddin and Bauermeister, Anelize and Bauman, Katherine D. and Baunach, Martin and Beemelmanns, Christine and Beman, J. Michael and Berlanga-Clavero, Mar{\´i}a Victoria and Blacutt, Alex A. and Bode, Helge B. and Boullie, Anne and Brejnrod, Asker and Bugni, Tim S. and Calteau, Alexandra and Cao, Liu and Carri{\´o}n, V{\´i}ctor J. and Castelo-Branco, Raquel and Chanana, Shaurya and Chase, Alexander B. and Chevrette, Marc G. and Costa-Lotufo, Leticia V. and Crawford, Jason M. and Currie, Cameron R. and Cuypers, Bart and Dang, Tam and de Rond, Tristan and Demko, Alyssa M. and Dittmann, Elke and Du, Chao and Drozd, Christopher and Dujardin, Jean-Claude and Dutton, Rachel J. and Edlund, Anna and Fewer, David P. and Garg, Neha and Gauglitz, Julia M. and Gentry, Emily C. and Gerwick, Lena and Glukhov, Evgenia and Gross, Harald and Gugger, Muriel and Guill{\´e}n Matus, Dulce G. and Helfrich, Eric J. N. and Hempel, Benjamin-Florian and Hur, Jae-Seoun and Iorio, Marianna and Jensen, Paul R. and Kang, Kyo Bin and Kaysser, Leonard and Kelleher, Neil L. and Kim, Chung Sub and Kim, Ki Hyun and Koester, Irina and K{\"o}nig, Gabriele M. and Leao, Tiago and Lee, Seoung Rak and Lee, Yi-Yuan and Li, Xuanji and Little, Jessica C. and Maloney, Katherine N. and M{\"a}nnle, Daniel and Martin H, Christian and McAvoy, Andrew C. and Metcalf, Willam W. and Mohimani, Hosein and Molina-Santiago, Carlos and Moore, Bradley S. and Mullowney, Michael W. and Muskat, Mitchell and Nothias, Louis-F{\´e}lix and O'Neill, Ellis C. and Parkinson, Elizabeth I. and Petras, Daniel and Piel, J{\"o}rn and Pierce, Emily C. and Pires, Karine and Reher, Raphael and Romero, Diego and Roper, M. Caroline and Rust, Michael and Saad, Hamada and Saenz, Carmen and Sanchez, Laura M. and S{\o}rensen, S{\o}ren Johannes and Sosio, Margherita and S{\"u}ssmuth, Roderich D. and Sweeney, Douglas and Tahlan, Kapil and Thomson, Regan J. and Tobias, Nicholas J. and Trindade-Silva, Amaro E. and van Wezel, Gilles P. and Wang, Mingxun and Weldon, Kelly C. and Zhang, Fan and Ziemert, Nadine and Duncan, Katherine R. and Cr{\"u}semann, Max and Rogers, Simon and Dorrestein, Pieter C. and Medema, Marnix H. and van der Hooft, Justin J. J.}, title = {A community resource for paired genomic and metabolomic data mining}, series = {Nature Chemical Biology}, volume = {17}, journal = {Nature Chemical Biology}, number = {4}, publisher = {Nature}, issn = {1552-4469}, doi = {10.1038/s41589-020-00724-z}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34708}, pages = {363 -- 368}, year = {2021}, language = {en} } @article{BeniddirKangGentaJouveetal.2021, author = {Beniddir, Mehdi A. and Kang, Kyo Bin and Genta-Jouve, Gr{\´e}gory and Huber, Florian and Rogers, Simon and van der Hooft, Justin J. J.}, title = {Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches}, series = {Natural Product Reports}, volume = {38}, journal = {Natural Product Reports}, number = {11}, publisher = {The Royal Society of Chemistry}, issn = {1460-4752}, doi = {10.1039/D1NP00023C}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34772}, pages = {1967 -- 1993}, year = {2021}, language = {en} } @article{HuberBoireLopezetal.2015, author = {Huber, Florian and Boire, Adeline and L{\´o}pez, Magdalena Preciado and Koenderink, Gijsje H.}, title = {Cytoskeletal crosstalk: when three different personalities team up}, series = {Current Opinion in Cell Biology}, volume = {32}, journal = {Current Opinion in Cell Biology}, publisher = {Elsevier}, issn = {1879-0410}, doi = {10.1016/j.ceb.2014.10.005}, pages = {39 -- 47}, year = {2015}, language = {en} } @article{HuberKaes2011, author = {Huber, Florian and K{\"a}s, Josef}, title = {Self-regulative organization of the cytoskeleton}, series = {Cytoskeleton}, volume = {68}, journal = {Cytoskeleton}, number = {5}, publisher = {Wiley}, issn = {1949-3592}, doi = {10.1002/cm.20509}, pages = {259 -- 265}, year = {2011}, abstract = {Despite its impressive complexity the cytoskeleton succeeds to persistently organize itself and thus the cells' interior. In contrast to classical man-made machines, much of the cellular organization originates from inherent self-assembly and self-organization allowing a high degree of autonomy for various functional units. Recent experimental and theoretical studies revealed numerous examples of cytoskeleton components that arrange and organize in a self-regulative way. In the present review we want to shortly summarize some of the principle mechanisms that are able to inherently trigger and regulate the cytoskeleton organization. Although taken individually most of these regulative principles are rather simple with intuitively predictable consequences, combinations of two or more of these mechanisms can quickly give rise to very complex, unexpected behavior and might even be able to explain the formation of different functional units out of a common pool of available building blocks.}, language = {en} } @article{HuberKaesStuhrmann2008, author = {Huber, Florian and K{\"a}s, Josef and Stuhrmann, Bj{\"o}rn}, title = {Growing actin networks form lamellipodium and lamellum by self-assembly}, series = {Biophysical Journal}, volume = {95}, journal = {Biophysical Journal}, number = {12}, publisher = {Biophysical Society}, issn = {1542-0086}, doi = {10.1529/biophysj.108.134817}, pages = {5508 -- 5523}, year = {2008}, abstract = {Many different cell types are able to migrate by formation of a thin actin-based cytoskeletal extension. Recently, it became evident that this extension consists of two distinct substructures, designated lamellipodium and lamellum, which differ significantly in their kinetic and kinematic properties as well as their biochemical composition. We developed a stochastic two-dimensional computer simulation that includes chemical reaction kinetics, G-actin diffusion, and filament transport to investigate the formation of growing actin networks in migrating cells. Model parameters were chosen based on experimental data or theoretical considerations. In this work, we demonstrate the system's ability to form two distinct networks by self-organization. We found a characteristic transition in mean filament length as well as a distinct maximum in depolymerization flux, both within the first 1-2 microm. The separation into two distinct substructures was found to be extremely robust with respect to initial conditions and variation of model parameters. We quantitatively investigated the complex interplay between ADF/cofilin and tropomyosin and propose a plausible mechanism that leads to spatial separation of, respectively, ADF/cofilin- or tropomyosin-dominated compartments. Tropomyosin was found to play an important role in stabilizing the lamellar actin network. Furthermore, the influence of filament severing and annealing on the network properties is explored, and simulation data are compared to existing experimental data.}, language = {en} } @article{HuberSchnaussRoenickeetal.2013, author = {Huber, Florian and Schnauß, J{\"o}rg and R{\"o}nicke, S. and Rauch, P. and M{\"u}ller, K. and F{\"u}tterer, C. and K{\"a}s, Josef}, title = {Emergent complexity of the cytoskeleton: from single filaments to tissue}, series = {Advances in Physics}, volume = {62}, journal = {Advances in Physics}, number = {1}, publisher = {Taylor \& Francis}, issn = {1460-6976}, doi = {10.1080/00018732.2013.771509}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34812}, pages = {1 -- 112}, year = {2013}, abstract = {Despite their overwhelming complexity, living cells display a high degree of internal mechanical and functional organization which can largely be attributed to the intracellular biopolymer scaffold, the cytoskeleton. Being a very complex system far from thermodynamic equilibrium, the cytoskeleton's ability to organize is at the same time challenging and fascinating. The extensive amounts of frequently interacting cellular building blocks and their inherent multifunctionality permits highly adaptive behavior and obstructs a purely reductionist approach. Nevertheless (and despite the field's relative novelty), the physics approach has already proved to be extremely successful in revealing very fundamental concepts of cytoskeleton organization and behavior. This review aims at introducing the physics of the cytoskeleton ranging from single biopolymer filaments to multicellular organisms. Throughout this wide range of phenomena, the focus is set on the intertwined nature of the different physical scales (levels of complexity) that give rise to numerous emergent properties by means of self-organization or self-assembly.}, language = {en} } @article{HuberStrehleKaes2012, author = {Huber, Florian and Strehle, Dan and Kaes, Josef}, title = {Counterion-induced formation of regular actin bundle networks}, series = {Soft Matter}, volume = {8}, journal = {Soft Matter}, number = {4}, publisher = {Royal Society of Chemistry}, issn = {1744-6848}, pages = {931 -- 936}, year = {2012}, language = {en} } @article{HuberStrehleSchnaussetal.2015, author = {Huber, Florian and Strehle, Dan and Schnauß, J{\"o}rg and K{\"a}s, Josef}, title = {Formation of regularly spaced networks as a general feature of actin bundle condensation by entropic forces}, series = {New Journal of Physics}, volume = {17}, journal = {New Journal of Physics}, number = {4}, publisher = {IOP Publishing}, issn = {1367-2630}, doi = {10.1088/1367-2630/17/4/043029}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34833}, year = {2015}, language = {en} } @article{HubervanderBurgvanderHooftetal.2021, author = {Huber, Florian and van der Burg, Sven and van der Hooft, Justin J. J. and Ridder, Lars}, title = {MS2DeepScore: a novel deep learning similarity measure to compare tandem mass spectra}, series = {Journal of Cheminformatics}, volume = {13}, journal = {Journal of Cheminformatics}, number = {1}, publisher = {Cold Spring Harbor Laboratory}, issn = {1758-2946}, doi = {10.1186/s13321-021-00558-4}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34847}, pages = {84}, year = {2021}, abstract = {Mass spectrometry data is one of the key sources of information in many workflows in medicine and across the life sciences. Mass fragmentation spectra are generally considered to be characteristic signatures of the chemical compound they originate from, yet the chemical structure itself usually cannot be easily deduced from the spectrum. Often, spectral similarity measures are used as a proxy for structural similarity but this approach is strongly limited by a generally poor correlation between both metrics. Here, we propose MS2DeepScore: a novel Siamese neural network to predict the structural similarity between two chemical structures solely based on their MS/MS fragmentation spectra. Using a cleaned dataset of > 100,000 mass spectra of about 15,000 unique known compounds, we trained MS2DeepScore to predict structural similarity scores for spectrum pairs with high accuracy. In addition, sampling different model varieties through Monte-Carlo Dropout is used to further improve the predictions and assess the model's prediction uncertainty. On 3600 spectra of 500 unseen compounds, MS2DeepScore is able to identify highly-reliable structural matches and to predict Tanimoto scores for pairs of molecules based on their fragment spectra with a root mean squared error of about 0.15. Furthermore, the prediction uncertainty estimate can be used to select a subset of predictions with a root mean squared error of about 0.1. Furthermore, we demonstrate that MS2DeepScore outperforms classical spectral similarity measures in retrieving chemically related compound pairs from large mass spectral datasets, thereby illustrating its potential for spectral library matching. Finally, MS2DeepScore can also be used to create chemically meaningful mass spectral embeddings that could be used to cluster large numbers of spectra. Added to the recently introduced unsupervised Spec2Vec metric, we believe that machine learning-supported mass spectral similarity measures have great potential for a range of metabolomics data processing pipelines.}, language = {en} } @article{HuberVerhoevenMeijeretal.2020, author = {Huber, Florian and Verhoeven, Stefan and Meijer, Christiaan and Spreeuw, Hanno and Castilla, Efra{\´i}n and Geng, Cunliang and van der Hooft, Justin J. J. and Rogers, Simon and Belloum, Adam and Diblen, Faruk and Spaaks, Jurriaan H.}, title = {matchms - processing and similarity evaluation of mass spectrometry data}, series = {Journal of Open Source Software}, volume = {5}, journal = {Journal of Open Source Software}, number = {52}, publisher = {Cold Spring Harbor Laboratory}, issn = {2475-9066}, doi = {10.21105/joss.02411}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34856}, pages = {2411}, year = {2020}, language = {en} } @article{PreciadoLopezHuberGrigorievetal.2014, author = {Preciado L{\´o}pez, Magdalena and Huber, Florian and Grigoriev, Ilya and Steinmetz, Michel O. and Akhmanova, Anna and Dogterom, Marileen and Koenderink, Gijsje H.}, title = {In vitro reconstitution of dynamic microtubules interacting with actin filament networks}, series = {Methods in Enzymology}, volume = {540}, journal = {Methods in Enzymology}, publisher = {Elsevier}, issn = {1557-7988}, doi = {10.1016/B978-0-12-397924-7.00017-0}, pages = {301 -- 320}, year = {2014}, language = {en} } @article{PreciadoLopezHuberGrigorievetal.2014, author = {Preciado L{\´o}pez, Magdalena and Huber, Florian and Grigoriev, Ilya and Steinmetz, Michel O. and Akhmanova, Anna and Koenderink, Gijsje H. and Dogterom, Marileen}, title = {Actin-microtubule coordination at growing microtubule ends}, series = {Nature Communications}, volume = {5}, journal = {Nature Communications}, publisher = {Springer Nature}, issn = {2041-1723}, doi = {10.1038/ncomms5778}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34878}, pages = {4778}, year = {2014}, abstract = {To power dynamic processes in cells, the actin and microtubule cytoskeletons organize into complex structures. Although it is known that cytoskeletal coordination is vital for cell function, the mechanisms by which cross-linking proteins coordinate actin and microtubule activities remain poorly understood. In particular, it is unknown how the distinct mechanical properties of different actin architectures modulate the outcome of actin-microtubule interactions. To address this question, we engineered the protein TipAct, which links growing microtubule ends via end-binding proteins to actin filaments. We show that growing microtubules can be captured and guided by stiff actin bundles, leading to global actin-microtubule alignment. Conversely, growing microtubule ends can transport, stretch and bundle individual actin filaments, thereby globally defining actin filament organization. Our results provide a physical basis to understand actin-microtubule cross-talk, and reveal that a simple cross-linker can enable a mechanical feedback between actin and microtubule organization that is relevant to diverse biological contexts.}, language = {en} }