@article{ElversSteffens2017, author = {Elvers, Paul and Steffens, Jochen}, title = {The Sound of Success: Investigating Cognitive and Behavioral Effects of Motivational Music in Sports}, series = {Frontiers in psychology}, volume = {8}, journal = {Frontiers in psychology}, publisher = {Frontiers}, doi = {10.3389/fpsyg.2017.02026}, year = {2017}, abstract = {Listening to music before, during, or after sports is a common phenomenon, yet its functions and effects on performance, cognition, and behavior remain to be investigated. Listening to music before, during, or after sports is a common phenomenon, yet its functions and effects on performance, cognition, and behavior remain to be investigated. In this study we present a novel approach to the role of music in sports and exercise that focuses on the notion of musical self-enhancement (Elvers, 2016). We derived the following hypotheses from this framework: listening to motivational music will (i) enhance self-evaluative cognition, (ii) improve performance in a ball game, and (iii) evoke greater risk-taking behavior. To evaluate the hypotheses, we conducted a between-groups experiment (N = 150) testing the effectiveness of both an experimenter playlist and a participant-selected playlist in comparison to a no-music control condition. All participants performed a ball-throwing task developed by Decharms and Dav{\´e} (1965), consisting of two parts: First, participants threw the ball from fixed distances into a funnel basket. During this task, performance was measured. In the second part, the participants themselves chose distances from the basket, which allowed their risk-taking behavior to be assessed. The results indicate that listening to motivational music led to greater risk taking but did not improve ball-throwing performance. This effect was more pronounced in male participants and among those who listened to their own playlists. Furthermore, self-selected music enhanced state self-esteem in participants who were performing well but not in those who were performing poorly. We also discuss further implications for the notion of musical self-enhancement. // Listening to music before, during, or after sports is a common phenomenon, yet its functions and effects on performance, cognition, and behavior remain to be investigated. In this study we present a novel approach to the role of music in sports and exercise that focuses on the notion of musical self-enhancement (Elvers, 2016). We derived the following hypotheses from this framework: listening to motivational music will (i) enhance self-evaluative cognition, (ii) improve performance in a ball game, and (iii) evoke greater risk-taking behavior. To evaluate the hypotheses, we conducted a between-groups experiment (N = 150) testing the effectiveness of both an experimenter playlist and a participant-selected playlist in comparison to a no-music control condition. All participants performed a ball-throwing task developed by Decharms and Dav{\´e} (1965), consisting of two parts: First, participants threw the ball from fixed distances into a funnel basket. During this task, performance was measured. In the second part, the participants themselves chose distances from the basket, which allowed their risk-taking behavior to be assessed. The results indicate that listening to motivational music led to greater risk taking but did not improve ball-throwing performance. This effect was more pronounced in male participants and among those who listened to their own playlists. Furthermore, self-selected music enhanced state self-esteem in participants who were performing well but not in those who were performing poorly. We also discuss further implications for the notion of musical self-enhancement.}, language = {en} } @article{GrebSteffensSchlotz2019, author = {Greb, Fabian and Steffens, Jochen and Schlotz, Wolff}, title = {Modeling Music-Selection Behavior in Everyday Life: A Multilevel Statistical Learning Approach and Mediation Analysis of Experience Sampling Data}, series = {Frontiers in psychology}, volume = {10}, journal = {Frontiers in psychology}, publisher = {Frontiers}, doi = {10.3389/fpsyg.2019.00390}, year = {2019}, abstract = {Music listening has become a highly individualized activity with smartphones and music streaming services providing listeners with absolute freedom to listen to any kind of music in any situation. Until now, little has been written about the processes underlying the selection of music in daily life. The present study aimed to disentangle some of the complex processes among the listener, situation, and functions of music listening involved in music selection. Utilizing the experience sampling method, data were collected from 119 participants using a smartphone application. For 10 consecutive days, participants received 14 prompts using stratified-random sampling throughout the day and reported on their music-listening behavior. Statistical learning procedures on multilevel regression models and multilevel structural equation modeling were used to determine the most important predictors and analyze mediation processes between person, situation, functions of listening, and music selection. Results revealed that the features of music selected in daily life were predominantly determined by situational characteristics, whereas consistent individual differences were of minor importance. Functions of music listening were found to act as a mediator between characteristics of the situation and music-selection behavior. We further observed several significant random effects, which indicated that individuals differed in how situational variables affected their music selection behavior. Our findings suggest a need to shift the focus of music-listening research from individual differences to situational influences, including potential person-situation interactions.}, language = {en} } @article{LuizardSteffensWeinzierl2020, author = {Luizard, Paul and Steffens, Jochen and Weinzierl, Stefan}, title = {Singing in different rooms: Common or individual adaptation patterns to the acoustic conditions?}, series = {The Journal of the Acoustical Society of America}, volume = {147}, journal = {The Journal of the Acoustical Society of America}, number = {2}, publisher = {ASA}, doi = {10.1121/10.0000715}, year = {2020}, language = {en} } @article{SchittkowskiRulandLaudenschlegeretal.2018, author = {Schittkowski, Julian and Ruland, Holger and Laudenschleger, Daniel and Girod, Kai and K{\"a}hler, Kevin and Kaluza, Stefan and Muhler, Martin and Schl{\"o}gl, Robert}, title = {Methanol Synthesis from Steel Mill Exhaust Gases: Challenges for the Industrial Cu/ZnO/Al 2 O 3 Catalyst}, series = {Chemie Ingenieur Technik}, volume = {90}, journal = {Chemie Ingenieur Technik}, number = {10}, publisher = {Wiley}, issn = {1522-2640}, doi = {10.1002/cite.201800017}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34526}, pages = {1419 -- 1429}, year = {2018}, language = {en} } @article{UnterfraunerVoigtHofer2021, author = {Unterfrauner, Elisabeth and Voigt, Christian and Hofer, Margit}, title = {The effect of maker and entrepreneurial education on self-efficacy and creativity}, series = {Entrepreneurship Education}, volume = {4}, journal = {Entrepreneurship Education}, number = {4}, publisher = {Springer Nature}, issn = {2520-8152}, doi = {10.1007/s41959-021-00060-w}, pages = {403 -- 424}, year = {2021}, language = {en} } @article{UnterfraunerVoigt2017, author = {Unterfrauner, Elisabeth and Voigt, Christian}, title = {Makers' ambitions to do socially valuable things}, series = {The Design Journal}, volume = {20}, journal = {The Design Journal}, number = {sup1}, publisher = {Taylor \& Francis}, issn = {1756-3062}, doi = {10.1080/14606925.2017.1352835}, pages = {3317 -- 3325}, year = {2017}, language = {en} } @article{SeebacherVanaVoigtetal.2021, author = {Seebacher, Lisa M. and Vana, Irina and Voigt, Christian and Tschank, Juliet}, title = {Is Science for Everyone? Exploring Intersectional Inequalities in Connecting With Science}, series = {Frontiers in Education}, volume = {6}, journal = {Frontiers in Education}, publisher = {Frontiers}, issn = {2504-284X}, doi = {10.3389/feduc.2021.673850}, year = {2021}, language = {en} } @article{MillardSorivelleDeljaninetal.2018, author = {Millard, Jeremy and Sorivelle, Marie and Deljanin, Sarah and Unterfrauner, Elisabeth and Voigt, Christian}, title = {Is the Maker Movement Contributing to Sustainability?}, series = {Sustainability}, volume = {10}, journal = {Sustainability}, number = {7}, publisher = {MDPI}, issn = {2071-1050}, doi = {10.3390/su10072212}, pages = {2212}, year = {2018}, language = {en} } @article{SchulzkeConradKaluzaetal.2017, author = {Schulzke, Tim and Conrad, Stefan and Kaluza, Stefan and van Loo, Tom}, title = {Upgrading of fast pyrolysis condensates via esterification with higher alcohols}, series = {Biomass and Bioenergy}, volume = {103}, journal = {Biomass and Bioenergy}, publisher = {Elsevier}, issn = {0961-9534}, doi = {10.1016/j.biombioe.2017.05.010}, pages = {11 -- 20}, year = {2017}, language = {en} } @article{JungePuringPiontekSmialkowskietal.2017, author = {Junge Puring, Kai and Piontek, Stefan and Smialkowski, Mathias and Burfeind, Jens and Kaluza, Stefan and Doetsch, Christian and Apfel, Ulf-Peter}, title = {Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications}, series = {Journal of visualized experiments : JoVE}, journal = {Journal of visualized experiments : JoVE}, number = {124}, publisher = {JoVE}, issn = {1940-087X}, doi = {10.3791/56087}, year = {2017}, abstract = {The rock material pentlandite with the composition Fe4.5Ni4.5S8 was synthesized via high temperature synthesis from the elements. The structure and composition of the material was characterized via powder X-ray diffraction (PXRD), M{\"o}ssbauer spectroscopy (MB), scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and energy dispersive X-ray spectroscopy (EDX). Two preparation methods of pentlandite bulk electrodes are presented. In the first approach a piece of synthetic pentlandite rock is directly contacted via a wire ferrule. The second approach utilizes pentlandite pellets, pressed from finely ground powder, which is immobilized in a Teflon casing. Both electrodes, whilst being prepared by an additive-free method, reveal high durability during electrocatalytic conversions in comparison to common drop-coating methods. We herein showcase the striking performance of such electrodes to accomplish the hydrogen evolution reaction (HER) and present a standardized method to evaluate the electrocatalytic performance by electrochemical and gas chromatographic methods. Furthermore, we report stability tests via potentiostatic methods at an overpotential of 0.6 V to explore the material limitations of the electrodes during electrolysis under industrial relevant conditions.}, language = {en} } @article{BordoloiSanchezNoeietal.2014, author = {Bordoloi, Ankur and Sanchez, Miguel and Noei, Heshmat and Kaluza, Stefan and Großmann, Dennis and Wang, Yuemin and Gr{\"u}nert, Wolfgang and Muhler, Martin}, title = {Catalytic Behaviour of Mesoporous Cobalt-Aluminum Oxides for CO Oxidation}, series = {Journal of Catalysts}, journal = {Journal of Catalysts}, publisher = {Hindawi}, issn = {2314-5110}, doi = {10.1155/2014/807545}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34344}, pages = {1 -- 9}, year = {2014}, language = {en} } @article{Haeusler2018, author = {H{\"a}usler, Alexander}, title = {Populismus auf der politischen B{\"u}hne}, series = {iQ konkret}, journal = {iQ konkret}, number = {1}, pages = {12}, year = {2018}, language = {de} } @article{ZanderKollmannsbergerRuessetal.2012, author = {Zander, Nils and Kollmannsberger, Stefan and Ruess, Martin and Yosibash, Z. and Rank, Ernst}, title = {The Finite Cell Method for linear thermoelasticity}, series = {Computers \& Mathematics with Applications}, volume = {64}, journal = {Computers \& Mathematics with Applications}, number = {11}, publisher = {Elsevier}, issn = {0898-1221}, doi = {10.1016/j.camwa.2012.09.002}, pages = {3527 -- 3541}, year = {2012}, language = {en} } @article{GuoRuess2015, author = {Guo, Yujie and Ruess, Martin}, title = {Weak Dirichlet boundary conditions for trimmed thin isogeometric shells}, series = {Computers \& Mathematics with Applications}, volume = {70}, journal = {Computers \& Mathematics with Applications}, number = {7}, publisher = {Elsevier}, issn = {0898-1221}, doi = {10.1016/j.camwa.2015.06.012}, pages = {1425 -- 1440}, year = {2015}, language = {de} } @article{GuoHellerHughesetal.2018, author = {Guo, Yujie and Heller, Jason and Hughes, Thomas J.R. and Ruess, Martin and Schillinger, Dominik}, title = {Variationally consistent isogeometric analysis of trimmed thin shells at finite deformations, based on the STEP exchange format}, series = {Computer Methods in Applied Mechanics and Engineering}, volume = {336}, journal = {Computer Methods in Applied Mechanics and Engineering}, publisher = {Elsevier}, issn = {0045-7825}, doi = {10.1016/j.cma.2018.02.027}, pages = {39 -- 79}, year = {2018}, language = {en} } @article{GroenLangelaarSigmundetal.2017, author = {Groen, Jeroen P. and Langelaar, Matthijs and Sigmund, Ole and Ruess, Martin}, title = {Higher-order multi-resolution topology optimization using the finite cell method}, series = {International Journal for Numerical Methods in Engineering}, volume = {110}, journal = {International Journal for Numerical Methods in Engineering}, number = {10}, publisher = {Wiley}, issn = {1097-0207}, doi = {10.1002/nme.5432}, pages = {903 -- 920}, year = {2017}, language = {en} } @article{AmanoMatsushitaYanagawaetal.1998, author = {Amano, Katsumi and Matsushita, Fumio and Yanagawa, Hirofumi and Cohen, Michael and Herder, Jens and Martens, William and Koba, Yoshiharu and Tohyama, Mikio}, title = {A Virtual Reality Sound System Using Room-Related Transfer Functions Delivered Through a Multispeaker Array: the PSFC at the University of Aizu Multimedia Center}, series = {TVRSJ}, volume = {3}, journal = {TVRSJ}, number = {1}, publisher = {J-STAGE}, doi = {10.18974/tvrsj.3.1_1}, pages = {1 -- 12}, year = {1998}, abstract = {The PSFC, or Pioneer Sound Field Controller, is a DSP-driven hemispherical loudspeaker array, installed at the University of Aizu Multimedia Center. The PSFC features realtime manipulation of the primary components of sound spatialization for each of two audio sources located in a virtual environment, including the content (apparent direction and distance) and context (room characteristics: reverberation level, room size and liveness). In an alternate mode, it can also direct the destination of the two separate input signals across 14 loudspeakers, manipulating the direction of the virtual sound sources with no control over apparent distance other than that afforded by source loudness (including no simulated environmental reflections or reverberation). The PSFC speaker dome is about 10 m in diameter, accommodating about fifty simultaneous users, including about twenty users comfortably standing or sitting near its ``sweet spot,'' the area in which the illusions of sound spatialization are most vivid. Collocated with a large screen rear-projection stereographic display, the PSFC is intended for advanced multimedia and virtual reality applications.}, language = {en} } @article{HuberSchnaussRoenickeetal.2013, author = {Huber, Florian and Schnauß, J{\"o}rg and R{\"o}nicke, S. and Rauch, P. and M{\"u}ller, K. and F{\"u}tterer, C. and K{\"a}s, Josef}, title = {Emergent complexity of the cytoskeleton: from single filaments to tissue}, series = {Advances in Physics}, volume = {62}, journal = {Advances in Physics}, number = {1}, publisher = {Taylor \& Francis}, issn = {1460-6976}, doi = {10.1080/00018732.2013.771509}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34812}, pages = {1 -- 112}, year = {2013}, abstract = {Despite their overwhelming complexity, living cells display a high degree of internal mechanical and functional organization which can largely be attributed to the intracellular biopolymer scaffold, the cytoskeleton. Being a very complex system far from thermodynamic equilibrium, the cytoskeleton's ability to organize is at the same time challenging and fascinating. The extensive amounts of frequently interacting cellular building blocks and their inherent multifunctionality permits highly adaptive behavior and obstructs a purely reductionist approach. Nevertheless (and despite the field's relative novelty), the physics approach has already proved to be extremely successful in revealing very fundamental concepts of cytoskeleton organization and behavior. This review aims at introducing the physics of the cytoskeleton ranging from single biopolymer filaments to multicellular organisms. Throughout this wide range of phenomena, the focus is set on the intertwined nature of the different physical scales (levels of complexity) that give rise to numerous emergent properties by means of self-organization or self-assembly.}, language = {en} } @article{HuberRidderVerhoevenetal.2021, author = {Huber, Florian and Ridder, Lars and Verhoeven, Stefan and Spaaks, Jurriaan H. and Diblen, Faruk and Rogers, Simon and van der Hooft, Justin J. J.}, title = {Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships}, series = {PLOS Computational Biology}, volume = {17}, journal = {PLOS Computational Biology}, number = {2}, publisher = {Cold Spring Harbor Laboratory}, organization = {PLOS}, issn = {1553-7358}, doi = {10.1371/journal.pcbi.1008724}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34687}, year = {2021}, abstract = {Spectral similarity is used as a proxy for structural similarity in many tandem mass spectrometry (MS/MS) based metabolomics analyses such as library matching and molecular networking. Although weaknesses in the relationship between spectral similarity scores and the true structural similarities have been described, little development of alternative scores has been undertaken. Here, we introduce Spec2Vec, a novel spectral similarity score inspired by a natural language processing algorithm-Word2Vec. Spec2Vec learns fragmental relationships within a large set of spectral data to derive abstract spectral embeddings that can be used to assess spectral similarities. Using data derived from GNPS MS/MS libraries including spectra for nearly 13,000 unique molecules, we show how Spec2Vec scores correlate better with structural similarity than cosine-based scores. We demonstrate the advantages of Spec2Vec in library matching and molecular networking. Spec2Vec is computationally more scalable allowing structural analogue searches in large databases within seconds.}, language = {en} } @article{SchornVerhoevenRidderetal.2021, author = {Schorn, Michelle A. and Verhoeven, Stefan and Ridder, Lars and Huber, Florian and Acharya, Deepa D. and Aksenov, Alexander A. and Aleti, Gajender and Moghaddam, Jamshid Amiri and Aron, Allegra T. and Aziz, Saefuddin and Bauermeister, Anelize and Bauman, Katherine D. and Baunach, Martin and Beemelmanns, Christine and Beman, J. Michael and Berlanga-Clavero, Mar{\´i}a Victoria and Blacutt, Alex A. and Bode, Helge B. and Boullie, Anne and Brejnrod, Asker and Bugni, Tim S. and Calteau, Alexandra and Cao, Liu and Carri{\´o}n, V{\´i}ctor J. and Castelo-Branco, Raquel and Chanana, Shaurya and Chase, Alexander B. and Chevrette, Marc G. and Costa-Lotufo, Leticia V. and Crawford, Jason M. and Currie, Cameron R. and Cuypers, Bart and Dang, Tam and de Rond, Tristan and Demko, Alyssa M. and Dittmann, Elke and Du, Chao and Drozd, Christopher and Dujardin, Jean-Claude and Dutton, Rachel J. and Edlund, Anna and Fewer, David P. and Garg, Neha and Gauglitz, Julia M. and Gentry, Emily C. and Gerwick, Lena and Glukhov, Evgenia and Gross, Harald and Gugger, Muriel and Guill{\´e}n Matus, Dulce G. and Helfrich, Eric J. N. and Hempel, Benjamin-Florian and Hur, Jae-Seoun and Iorio, Marianna and Jensen, Paul R. and Kang, Kyo Bin and Kaysser, Leonard and Kelleher, Neil L. and Kim, Chung Sub and Kim, Ki Hyun and Koester, Irina and K{\"o}nig, Gabriele M. and Leao, Tiago and Lee, Seoung Rak and Lee, Yi-Yuan and Li, Xuanji and Little, Jessica C. and Maloney, Katherine N. and M{\"a}nnle, Daniel and Martin H, Christian and McAvoy, Andrew C. and Metcalf, Willam W. and Mohimani, Hosein and Molina-Santiago, Carlos and Moore, Bradley S. and Mullowney, Michael W. and Muskat, Mitchell and Nothias, Louis-F{\´e}lix and O'Neill, Ellis C. and Parkinson, Elizabeth I. and Petras, Daniel and Piel, J{\"o}rn and Pierce, Emily C. and Pires, Karine and Reher, Raphael and Romero, Diego and Roper, M. Caroline and Rust, Michael and Saad, Hamada and Saenz, Carmen and Sanchez, Laura M. and S{\o}rensen, S{\o}ren Johannes and Sosio, Margherita and S{\"u}ssmuth, Roderich D. and Sweeney, Douglas and Tahlan, Kapil and Thomson, Regan J. and Tobias, Nicholas J. and Trindade-Silva, Amaro E. and van Wezel, Gilles P. and Wang, Mingxun and Weldon, Kelly C. and Zhang, Fan and Ziemert, Nadine and Duncan, Katherine R. and Cr{\"u}semann, Max and Rogers, Simon and Dorrestein, Pieter C. and Medema, Marnix H. and van der Hooft, Justin J. J.}, title = {A community resource for paired genomic and metabolomic data mining}, series = {Nature Chemical Biology}, volume = {17}, journal = {Nature Chemical Biology}, number = {4}, publisher = {Nature}, issn = {1552-4469}, doi = {10.1038/s41589-020-00724-z}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34708}, pages = {363 -- 368}, year = {2021}, language = {en} } @article{AdamatzkySchnaussHuber2019, author = {Adamatzky, Andrew and Schnauß, J{\"o}rg and Huber, Florian}, title = {Actin droplet machine}, series = {Royal Society Open Science}, volume = {6}, journal = {Royal Society Open Science}, number = {12}, publisher = {Royal Soc. Publ.}, issn = {2054-5703}, doi = {10.1098/rsos.191135}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34675}, year = {2019}, abstract = {The actin droplet machine is a computer model of a three-dimensional network of actin bundles developed in a droplet of a physiological solution, which implements mappings of sets of binary strings. The actin bundle network is conductive to travelling excitations, i.e. impulses. The machine is interfaced with an arbitrary selected set of k electrodes through which stimuli, binary strings of length k represented by impulses generated on the electrodes, are applied and responses are recorded. The responses are recorded in a form of impulses and then converted to binary strings. The machine's state is a binary string of length k: if there is an impulse recorded on the ith electrode, there is a '1' in the ith position of the string, and '0' otherwise. We present a design of the machine and analyse its state transition graphs. We envisage that actin droplet machines could form an elementary processor of future massive parallel computers made from biopolymers.}, language = {en} } @article{AdamatzkyHuberSchnauss2019, author = {Adamatzky, Andrew and Huber, Florian and Schnauß, J{\"o}rg}, title = {Computing on actin bundles network}, series = {Scientific Reports}, volume = {9}, journal = {Scientific Reports}, number = {1}, publisher = {Springer Nature}, issn = {2045-2322}, doi = {10.1038/s41598-019-51354-y}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34665}, year = {2019}, abstract = {Actin filaments are conductive to ionic currents, mechanical and voltage solitons. These travelling localisations can be utilised to generate computing circuits from actin networks. The propagation of localisations on a single actin filament is experimentally unfeasible to control. Therefore, we consider excitation waves propagating on bundles of actin filaments. In computational experiments with a two-dimensional slice of an actin bundle network we show that by using an arbitrary arrangement of electrodes, it is possible to implement two-inputs-one-output circuits.}, language = {en} } @article{MiguelesRowlandsHuberetal.2019, author = {Migueles, Jairo H. and Rowlands, Alex V. and Huber, Florian and Sabia, S{\´e}verine and van Hees, Vincent T.}, title = {GGIR: A Research Community-Driven Open Source R Package for Generating Physical Activity and Sleep Outcomes From Multi-Day Raw Accelerometer Data}, series = {Journal for the Measurement of Physical Behaviour}, volume = {2}, journal = {Journal for the Measurement of Physical Behaviour}, number = {3}, publisher = {Human Kinetics}, issn = {2575-6605}, doi = {10.1123/jmpb.2018-0063}, pages = {188 -- 196}, year = {2019}, language = {en} } @article{BeniddirKangGentaJouveetal.2021, author = {Beniddir, Mehdi A. and Kang, Kyo Bin and Genta-Jouve, Gr{\´e}gory and Huber, Florian and Rogers, Simon and van der Hooft, Justin J. J.}, title = {Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches}, series = {Natural Product Reports}, volume = {38}, journal = {Natural Product Reports}, number = {11}, publisher = {The Royal Society of Chemistry}, issn = {1460-4752}, doi = {10.1039/D1NP00023C}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34772}, pages = {1967 -- 1993}, year = {2021}, language = {en} } @article{HuberStrehleSchnaussetal.2015, author = {Huber, Florian and Strehle, Dan and Schnauß, J{\"o}rg and K{\"a}s, Josef}, title = {Formation of regularly spaced networks as a general feature of actin bundle condensation by entropic forces}, series = {New Journal of Physics}, volume = {17}, journal = {New Journal of Physics}, number = {4}, publisher = {IOP Publishing}, issn = {1367-2630}, doi = {10.1088/1367-2630/17/4/043029}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34833}, year = {2015}, language = {en} } @article{HuberVerhoevenMeijeretal.2020, author = {Huber, Florian and Verhoeven, Stefan and Meijer, Christiaan and Spreeuw, Hanno and Castilla, Efra{\´i}n and Geng, Cunliang and van der Hooft, Justin J. J. and Rogers, Simon and Belloum, Adam and Diblen, Faruk and Spaaks, Jurriaan H.}, title = {matchms - processing and similarity evaluation of mass spectrometry data}, series = {Journal of Open Source Software}, volume = {5}, journal = {Journal of Open Source Software}, number = {52}, publisher = {Cold Spring Harbor Laboratory}, issn = {2475-9066}, doi = {10.21105/joss.02411}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34856}, pages = {2411}, year = {2020}, language = {en} } @article{HuberKaesStuhrmann2008, author = {Huber, Florian and K{\"a}s, Josef and Stuhrmann, Bj{\"o}rn}, title = {Growing actin networks form lamellipodium and lamellum by self-assembly}, series = {Biophysical Journal}, volume = {95}, journal = {Biophysical Journal}, number = {12}, publisher = {Biophysical Society}, issn = {1542-0086}, doi = {10.1529/biophysj.108.134817}, pages = {5508 -- 5523}, year = {2008}, abstract = {Many different cell types are able to migrate by formation of a thin actin-based cytoskeletal extension. Recently, it became evident that this extension consists of two distinct substructures, designated lamellipodium and lamellum, which differ significantly in their kinetic and kinematic properties as well as their biochemical composition. We developed a stochastic two-dimensional computer simulation that includes chemical reaction kinetics, G-actin diffusion, and filament transport to investigate the formation of growing actin networks in migrating cells. Model parameters were chosen based on experimental data or theoretical considerations. In this work, we demonstrate the system's ability to form two distinct networks by self-organization. We found a characteristic transition in mean filament length as well as a distinct maximum in depolymerization flux, both within the first 1-2 microm. The separation into two distinct substructures was found to be extremely robust with respect to initial conditions and variation of model parameters. We quantitatively investigated the complex interplay between ADF/cofilin and tropomyosin and propose a plausible mechanism that leads to spatial separation of, respectively, ADF/cofilin- or tropomyosin-dominated compartments. Tropomyosin was found to play an important role in stabilizing the lamellar actin network. Furthermore, the influence of filament severing and annealing on the network properties is explored, and simulation data are compared to existing experimental data.}, language = {en} } @article{HuberKaes2011, author = {Huber, Florian and K{\"a}s, Josef}, title = {Self-regulative organization of the cytoskeleton}, series = {Cytoskeleton}, volume = {68}, journal = {Cytoskeleton}, number = {5}, publisher = {Wiley}, issn = {1949-3592}, doi = {10.1002/cm.20509}, pages = {259 -- 265}, year = {2011}, abstract = {Despite its impressive complexity the cytoskeleton succeeds to persistently organize itself and thus the cells' interior. In contrast to classical man-made machines, much of the cellular organization originates from inherent self-assembly and self-organization allowing a high degree of autonomy for various functional units. Recent experimental and theoretical studies revealed numerous examples of cytoskeleton components that arrange and organize in a self-regulative way. In the present review we want to shortly summarize some of the principle mechanisms that are able to inherently trigger and regulate the cytoskeleton organization. Although taken individually most of these regulative principles are rather simple with intuitively predictable consequences, combinations of two or more of these mechanisms can quickly give rise to very complex, unexpected behavior and might even be able to explain the formation of different functional units out of a common pool of available building blocks.}, language = {en} } @article{StuhrmannHuberKaes2011, author = {Stuhrmann, Bj{\"o}rn and Huber, Florian and K{\"a}s, Josef}, title = {Robust organizational principles of protrusive biopolymer networks in migrating living cells}, series = {Plos One}, volume = {6}, journal = {Plos One}, number = {1}, publisher = {Public Library of Science (PLoS)}, issn = {1932-6203}, doi = {10.1371/journal.pone.0014471}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34901}, year = {2011}, abstract = {Cell migration is associated with the dynamic protrusion of a thin actin-based cytoskeletal extension at the cell front, which has been shown to consist of two different substructures, the leading lamellipodium and the subsequent lamellum. While the formation of the lamellipodium is increasingly well understood, organizational principles underlying the emergence of the lamellum are just beginning to be unraveled. We report here on a 1D mathematical model which describes the reaction-diffusion processes of a polarized actin network in steady state, and reproduces essential characteristics of the lamellipodium-lamellum system. We observe a steep gradient in filament lengths at the protruding edge, a local depolymerization maximum a few microns behind the edge, as well as a differential dominance of the network destabilizer ADF/cofilin and the stabilizer tropomyosin. We identify simple and robust organizational principles giving rise to the derived network characteristics, uncoupled from the specifics of any molecular implementation, and thus plausibly valid across cell types. An analysis of network length dependence on physico-chemical system parameters implies that to limit array treadmilling to cellular dimensions, network growth has to be truncated by mechanisms other than aging-induced depolymerization, e.g., by myosin-associated network dissociation at the transition to the cell body. Our work contributes to the analytical understanding of the cytoskeletal extension's bisection into lamellipodium and lamellum and sheds light on how cells organize their molecular machinery to achieve motility.}, language = {en} } @article{PreciadoLopezHuberGrigorievetal.2014, author = {Preciado L{\´o}pez, Magdalena and Huber, Florian and Grigoriev, Ilya and Steinmetz, Michel O. and Akhmanova, Anna and Koenderink, Gijsje H. and Dogterom, Marileen}, title = {Actin-microtubule coordination at growing microtubule ends}, series = {Nature Communications}, volume = {5}, journal = {Nature Communications}, publisher = {Springer Nature}, issn = {2041-1723}, doi = {10.1038/ncomms5778}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34878}, pages = {4778}, year = {2014}, abstract = {To power dynamic processes in cells, the actin and microtubule cytoskeletons organize into complex structures. Although it is known that cytoskeletal coordination is vital for cell function, the mechanisms by which cross-linking proteins coordinate actin and microtubule activities remain poorly understood. In particular, it is unknown how the distinct mechanical properties of different actin architectures modulate the outcome of actin-microtubule interactions. To address this question, we engineered the protein TipAct, which links growing microtubule ends via end-binding proteins to actin filaments. We show that growing microtubules can be captured and guided by stiff actin bundles, leading to global actin-microtubule alignment. Conversely, growing microtubule ends can transport, stretch and bundle individual actin filaments, thereby globally defining actin filament organization. Our results provide a physical basis to understand actin-microtubule cross-talk, and reveal that a simple cross-linker can enable a mechanical feedback between actin and microtubule organization that is relevant to diverse biological contexts.}, language = {en} } @article{JohanningBraunTimoneyetal.2009, author = {Johanning, M. and Braun, Alexander and Timoney, N. and Elman, V. and Neuhauser, W. and Wunderlich, Chr}, title = {Individual addressing of trapped ions and coupling of motional and spin states using RF radiation}, series = {Physical review letters}, volume = {102}, journal = {Physical review letters}, number = {7}, publisher = {American Physical Society}, issn = {1079-7114}, doi = {10.1103/PhysRevLett.102.073004}, year = {2009}, abstract = {Individual electrodynamically trapped and laser cooled ions are addressed in frequency space using radio-frequency radiation in the presence of a static magnetic field gradient. In addition, an interaction between motional and spin states induced by an rf field is demonstrated employing rf optical double resonance spectroscopy. These are two essential experimental steps towards realizing a novel concept for implementing quantum simulations and quantum computing with trapped ions.}, language = {en} } @article{JohanningBraunEiteneueretal.2011, author = {Johanning, M. and Braun, Alexander and Eiteneuer, D. and Paape, C. and Balzer, C. and Neuhauser, W. and Wunderlich, C.}, title = {Resonance-enhanced isotope-selective photoionization of YbI for ion trap loading}, series = {Applied Physics B}, volume = {103}, journal = {Applied Physics B}, number = {2}, publisher = {Springer Nature}, issn = {1432-0649}, doi = {10.1007/s00340-011-4502-7}, pages = {327 -- 338}, year = {2011}, language = {en} } @article{VossMusallLichtmess2011, author = {Voss, Karsten and Musall, Eike and Lichtmeß, Markus}, title = {From Low Energy to Net Zero-Energy Buildings: Status and Perspectives}, series = {Journal of Green Building}, volume = {6}, journal = {Journal of Green Building}, number = {1}, publisher = {College Publishing}, doi = {10.3992/jgb.6.1.46}, pages = {46 -- 57}, year = {2011}, abstract = {"Net Zero-Energy Building" has become a popular catchphrase to describe the synergy between energy-efficient building and renewable energy utilisation to achieve a balanced energy budget over an annual cycle. Taking into account the energy exchange with a grid overcomes the limitations of energy-autonomous buildings with the need for seasonal energy storage on-site. Although the expression, "Net Zero-Energy Building," appears in many energy policy documents, a harmonised definition or a standardised balancing method is still lacking. This paper reports on the background and the various effects influencing the energy balance approach. After discussing the national energy code framework in Germany, a harmonised terminology and balancing procedure is proposed. The procedure takes not only the energy balance but also energy efficiency and load matching into account.}, language = {en} } @article{VossMusall2011, author = {Voss, Karsten and Musall, Eike}, title = {Null- und Plusenergiegeb{\"a}ude: Allgemeine Bilanzierungsverfahren und Schnittstellen zur normativen Praxis in Deutschland}, series = {EnEVaktuell}, journal = {EnEVaktuell}, number = {IV}, publisher = {DIN Deutsches Institut f{\"u}r Normung e.V.}, pages = {3 -- 5}, year = {2011}, abstract = {Die Begriffe „Nullenergiehaus" oder „Plusenergiehaus" sind in den letzten Jahren national und international zum Inbegriff f{\"u}r die konsequente Zusammenf{\"u}hrung von Maßnahmen zur drastischen Energieeinsparung und optimierter, dezentraler Nutzung erneuerbarer Energien geworden. Dabei geht es nicht um energieautarke Geb{\"a}ude und die dabei große Herausforderung der saisonalen Energiespeicherung. Grundidee ist, dass die von einem Geb{\"a}ude in ein Netz eingespeiste Energiemenge in der Jahresbilanz mindestens dem Energiebezug entspricht. Sowohl im Kontext der Fortf{\"u}hrung der europ{\"a}ischen Geb{\"a}uderichtline als auch im aktuellen Energiekonzept und Energieforschungsprogramm der Bundesregierung wird das Thema besetzt.}, language = {de} } @article{MusallVoss2014, author = {Musall, Eike and Voss, Karsten}, title = {Renewable Energy Ratio in Net Zero Energy Buildings}, series = {REHVA Journal}, volume = {51}, journal = {REHVA Journal}, number = {3}, publisher = {REHVA}, pages = {14 -- 18}, year = {2014}, language = {en} } @article{deBanffyHallHill2017, author = {de B{\´a}nffy-Hall, Alicia and Hill, Burkhard}, title = {Community Music: Eine Einf{\"u}hrung}, series = {KULTURELLE BILDUNG ONLINE}, journal = {KULTURELLE BILDUNG ONLINE}, publisher = {Bundesakademie f{\"u}r Kulturelle Bildung}, doi = {10.25529/92552.79}, year = {2017}, language = {de} } @article{deBanffyHallHill2017, author = {de B{\´a}nffy-Hall, Alicia and Hill, Burkhard}, title = {Community Music: Eine Einf{\"u}hrung}, series = {kubi-online}, journal = {kubi-online}, year = {2017}, language = {de} } @article{Hoerner2015, author = {H{\"o}rner, Fernand}, title = {La flexibilit{\´e} historique de l'aura : de Walter Benjamin {\`a} Radiohead}, series = {Communication \& Langages}, volume = {2}, journal = {Communication \& Langages}, number = {184}, publisher = {cairn-int.info}, organization = {cairn-int.info}, doi = {10.4074/S0336150015012041}, pages = {61 -- 77}, year = {2015}, language = {fr} } @article{HiesingerTophoven2019, author = {Hiesinger, Karolin and Tophoven, Silke}, title = {Job requirement level, work demands, and health: a prospective study among older workers}, series = {International Archives of Occupational and Environmental Health}, volume = {92}, journal = {International Archives of Occupational and Environmental Health}, publisher = {Springer Nature}, doi = {10.1007/s00420-019-01451-2}, pages = {1139 -- 1149}, year = {2019}, language = {en} } @article{HiesingerTophovenMarch2018, author = {Hiesinger, Karolin and Tophoven, Silke and March, Stefanie}, title = {Geschlechtsspezifische Verzerrungen bei der Erfassung von Depressivit{\"a}t}, series = {Pr{\"a}vention und Gesundheitsf{\"o}rderung}, volume = {13}, journal = {Pr{\"a}vention und Gesundheitsf{\"o}rderung}, number = {3}, publisher = {Springer Nature}, doi = {10.1007/s11553-017-0634-x}, pages = {211 -- 217}, year = {2018}, language = {de} } @article{Tophoven2017, author = {Tophoven, Silke}, title = {Buchbesprechung: Siegrist, J./Wahrendorf, M. (Hrsg.) (2016): Work Stress and Health in a Globalized Economy. The Model of Effort-Reward Imbalance. Cham: Springer International Publishing}, series = {WSI-Mitteilungen}, volume = {70}, journal = {WSI-Mitteilungen}, number = {3}, publisher = {Nomos}, pages = {224}, year = {2017}, language = {de} } @article{TophovenTisch2016, author = {Tophoven, Silke and Tisch, Anita}, title = {Dimensionen prek{\"a}rer Besch{\"a}ftigung und Gesundheit im mittleren Lebensalter}, series = {WSI-Mitteilungen}, volume = {69}, journal = {WSI-Mitteilungen}, number = {2}, publisher = {Nomos}, doi = {10.5771/0342-300X-2016-2-105}, pages = {105 -- 112}, year = {2016}, language = {de} } @article{KellyIrvingTophovenBlane2015, author = {Kelly-Irving, Michelle and Tophoven, Silke and Blane, David}, title = {Editorial: Life course research: new opportunities for establishing social and biological plausibility}, series = {International journal of public health}, volume = {60}, journal = {International journal of public health}, number = {6}, publisher = {Springer Nature}, doi = {10.1007/s00038-015-0688-5}, pages = {629 -- 630}, year = {2015}, language = {en} } @article{RauchTophovenEggsetal.2015, author = {Rauch, Angela and Tophoven, Silke and Eggs, Johannes and Tisch, Anita}, title = {Arbeitsbezogene gesundheitsrelevante Faktoren im fortgeschrittenen Erwerbsalter: eine Studie mit neuen Analysem{\"o}glichkeiten}, series = {WSI-Mitteilungen}, volume = {68}, journal = {WSI-Mitteilungen}, number = {3}, publisher = {Nomos}, doi = {10.5771/0342-300X-2015-3-212}, pages = {212 -- 218}, year = {2015}, language = {de} } @article{WillersDeckert2015, author = {Willers, Christoph and Deckert, Carsten}, title = {eFood in Deutschland}, series = {Der Betriebswirt}, volume = {56}, journal = {Der Betriebswirt}, number = {11}, publisher = {Duncker \& Humblot}, doi = {10.3790/dbw.56.4.10}, pages = {10 -- 15}, year = {2015}, abstract = {Im Vergleich zu „Pionierbranchen" wie Mode oder Medien steht der Online-Handel mit Lebensmitteln erst am Anfang. Dabei kann dieser zu einem Wettbewerbsvorteil werden - wenn der Handel es richtig angeht. Auf der anderen Seite steht das Risiko einer strategischen Falle, d.h. es wird unter Umst{\"a}nden aufgrund der Widerst{\"a}nde beim Verbraucher nur ein Nischenmarkt bedient, der eine geringe Profitabilit{\"a}t aufweist. Im Spannungsfeld „Marktpotenzial auf Handelsseite" vs. „Zur{\"u}ckhaltung beim Verbraucher" r{\"u}cken dabei Fragen der Kommunikationspolitik im Online-Lebensmittelhandel in den Fokus. F{\"u}r eine erfolgreiche Umsetzung stellt eine eindeutige Typologie eine notwendige Basis dar, um die konkreten Bed{\"u}rfnisse potenzieller Konsumenten anzusprechen. Ein Engagement im eFood-Bereich ist daher als Investition in die zuk{\"u}nftige Entwicklung der M{\"a}rkte und ihrer Zielgruppen zu betrachten. Although online trading in the food sector is still in early stages, it may become a competitive edge - if retailers go about it the right way. On the other hand, due to consumer resistance, there is the risk of serving only a niche market, which cannot be maintained in terms of profitability. Therefore, a stronger focus on communication policies is needed. Engaging in the eFood sector finally has to be seen as an important investment into future markets and their target groups. Keywords: online lebensmittelhandel, lieferfenster, informationszeitalter, face to the customer}, language = {de} } @article{KampaFinkeStalderetal.2022, author = {Kampa, Miriam and Finke, Johannes and Stalder, Tobias and Bucher, Leandra and Klapperich, Holger and Mertl, Fabian and Zimmer, Christian and Geiger, Christian and Hassenzahl, Marc and Klucken, Tim}, title = {Facilitating relaxation and stress reduction in healthy participants through a virtual reality intervention: study protocol for a non-inferiority randomized controlled trial}, series = {Trials}, volume = {23}, journal = {Trials}, publisher = {BMC}, issn = {1745-6215}, doi = {10.1186/s13063-022-06307-8}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-40118}, year = {2022}, language = {en} } @article{HubervanderBurgvanderHooftetal.2021, author = {Huber, Florian and van der Burg, Sven and van der Hooft, Justin J. J. and Ridder, Lars}, title = {MS2DeepScore: a novel deep learning similarity measure to compare tandem mass spectra}, series = {Journal of Cheminformatics}, volume = {13}, journal = {Journal of Cheminformatics}, number = {1}, publisher = {Cold Spring Harbor Laboratory}, issn = {1758-2946}, doi = {10.1186/s13321-021-00558-4}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:due62-opus-34847}, pages = {84}, year = {2021}, abstract = {Mass spectrometry data is one of the key sources of information in many workflows in medicine and across the life sciences. Mass fragmentation spectra are generally considered to be characteristic signatures of the chemical compound they originate from, yet the chemical structure itself usually cannot be easily deduced from the spectrum. Often, spectral similarity measures are used as a proxy for structural similarity but this approach is strongly limited by a generally poor correlation between both metrics. Here, we propose MS2DeepScore: a novel Siamese neural network to predict the structural similarity between two chemical structures solely based on their MS/MS fragmentation spectra. Using a cleaned dataset of > 100,000 mass spectra of about 15,000 unique known compounds, we trained MS2DeepScore to predict structural similarity scores for spectrum pairs with high accuracy. In addition, sampling different model varieties through Monte-Carlo Dropout is used to further improve the predictions and assess the model's prediction uncertainty. On 3600 spectra of 500 unseen compounds, MS2DeepScore is able to identify highly-reliable structural matches and to predict Tanimoto scores for pairs of molecules based on their fragment spectra with a root mean squared error of about 0.15. Furthermore, the prediction uncertainty estimate can be used to select a subset of predictions with a root mean squared error of about 0.1. Furthermore, we demonstrate that MS2DeepScore outperforms classical spectral similarity measures in retrieving chemically related compound pairs from large mass spectral datasets, thereby illustrating its potential for spectral library matching. Finally, MS2DeepScore can also be used to create chemically meaningful mass spectral embeddings that could be used to cluster large numbers of spectra. Added to the recently introduced unsupervised Spec2Vec metric, we believe that machine learning-supported mass spectral similarity measures have great potential for a range of metabolomics data processing pipelines.}, language = {en} } @article{KernebeckHollePogschebaetal.2019, author = {Kernebeck, Sven and Holle, Daniela and Pogscheba, Patrick and Jordan, Felix and Mertl, Fabian and Huldtgren, Alina and Bader, Sebastian and Kirste, Thomas and Teipel, Stefan and Holle, Bernhard and Halek, Margareta}, title = {A Tablet App- and Sensor-Based Assistive Technology Intervention for Informal Caregivers to Manage the Challenging Behavior of People With Dementia (the insideDEM Study): Protocol for a Feasibility Study}, series = {JMIR research protocols}, volume = {8}, journal = {JMIR research protocols}, number = {2}, publisher = {JMIR}, doi = {10.2196/11630}, year = {2019}, language = {en} } @article{GalbanMaderwaldEggebrechtetal.2005, author = {Galban, Craig and Maderwald, Stefan and Eggebrecht, Holger and Grote, Wolfgang and de Greiff, A. and Uffmann, K. and Ladd, M. E.}, title = {Monitoring the Effects of Chronic Obstructive Pulmonary Disease on Muscle Elasticity by MR Elastography}, series = {Proc. Intl. Soc. Mag. Reson. Med.}, volume = {13}, journal = {Proc. Intl. Soc. Mag. Reson. Med.}, pages = {2015}, year = {2005}, abstract = {Men afflicted with chronic obstructive pulmonary disease (COPD) show signs of muscle dysfunction, such as increased muscle fatigue and acidosis during exercise. We hypothesize that muscle elasticity of the lower extremities differs between patients with COPD and age-related controls. The shear modulus of the soleus muscle was measured non-invasively using MR elastography (MRE) at 0\%, 5\%, 10\%, 15\%, and 20\% of the subject's maximum applied force. The results from this study showed statistical differences between the patients and controls, even though there were no statistical differences in the maximum applied force.}, language = {en} } @article{GalbanMaderwaldHerrmannetal.2005, author = {Galban, Craig and Maderwald, Stefan and Herrmann, Burkhard and Brauck, K. and Grote, Wolfgang and de Greiff, A. and Uffmann, K. and Ladd, M.}, title = {Measuring Skeletal Muscle Elasticity in Patients with Hypogonadism by MR Elastography}, series = {Proc. Intl. Soc. Mag. Reson. Med.}, volume = {13}, journal = {Proc. Intl. Soc. Mag. Reson. Med.}, pages = {2016}, year = {2005}, abstract = {Men afflicted with hypogonadism have reduced fat-free mass and in some cases a loss in muscle strength. We hypothesize that muscle elasticity of the lower extremities differs between patients with hypogonadism and healthy controls. The shear modulus of the soleus muscle was measured non-invasively using MR elastography (MRE) at 0\%, 5\%, 10\%, 15\%, and 20\% of the subject's maximum applied force. The results from this study showed statistical differences between the patients and controls, even though there were no statistical differences in applied force.}, language = {en} }