TY - JOUR A1 - Galban, Craig A1 - Maderwald, Stefan A1 - Eggebrecht, Holger A1 - Grote, Wolfgang A1 - de Greiff, A. A1 - Uffmann, K. A1 - Ladd, M. E. T1 - Monitoring the Effects of Chronic Obstructive Pulmonary Disease on Muscle Elasticity by MR Elastography T2 - Proc. Intl. Soc. Mag. Reson. Med. N2 - Men afflicted with chronic obstructive pulmonary disease (COPD) show signs of muscle dysfunction, such as increased muscle fatigue and acidosis during exercise. We hypothesize that muscle elasticity of the lower extremities differs between patients with COPD and age-related controls. The shear modulus of the soleus muscle was measured non-invasively using MR elastography (MRE) at 0%, 5%, 10%, 15%, and 20% of the subject’s maximum applied force. The results from this study showed statistical differences between the patients and controls, even though there were no statistical differences in the maximum applied force. Y1 - 2005 UR - https://opus4.kobv.de/opus4-hs-duesseldorf/frontdoor/index/index/docId/4320 UR - https://cds.ismrm.org/protected/05MProceedings/PDFfiles/02015.pdf VL - 13 SP - 2015 ER -