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  <doc>
    <id>2627</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>27</pageFirst>
    <pageLast>34</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <articleNumber/>
    <type>conferenceobject</type>
    <publisherName>SciTePress</publisherName>
    <publisherPlace>Setúbal</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-08-09</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Patch-based Carcinoma Detection on Confocal Laser Endomicroscopy Images</title>
    <abstract language="deu">Deep learning technologies such as convolutional neural networks (CNN) provide powerful methods for image recognition and have recently been employed in the field of automated carcinoma detection in confocal laser endomicroscopy (CLE) images. CLE is a (sub-)surface microscopic imaging technique that reaches magnifications of up to 1000x and is thus suitable for in vivo structural tissue analysis. In this work, we aim to evaluate the prospects of a priorly developed deep learning-based algorithm targeted at the identification of oral squamous cell carcinoma with regard to its generalization to further anatomic locations of squamous cell carcinomas in the area of head and neck. We applied the algorithm on images acquired from the vocal fold area of five patients with histologically verified squamous cell carcinoma and presumably healthy control images of the clinically normal contra-lateral vocal cord. We find that the network trained on the oral cavity data reaches an accurac y of 89.45% and an area-under-the-curve (AUC) value of 0.955, when applied on the vocal cords data. Compared to the state of the art, we achieve very similar results, yet with an algorithm that was trained on a completely disjunct data set. Concatenating both data sets yielded further improvements in cross-validation with an accuracy of 90.81% and AUC of 0.970. In this study, for the first time to our knowledge, a deep learning mechanism for the identification of oral carcinomas using CLE Images could be applied to other disciplines in the area of head and neck. This study shows the prospect of the algorithmic approach to generalize well on other malignant entities of the head and neck, regardless of the anatomical location and furthermore in an examiner-independent manner.</abstract>
    <parentTitle language="eng">Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies</parentTitle>
    <subTitle language="eng">A Cross-Site Robustness Assessment</subTitle>
    <identifier type="isbn">978-989-758-278-3</identifier>
    <identifier type="urn">urn:nbn:de:bvb:573-26277</identifier>
    <enrichment key="THI_relatedIdentifier">https://doi.org/10.5220/0006534700270034</enrichment>
    <enrichment key="THI_review">peer-review</enrichment>
    <enrichment key="THI_openaccess">ja</enrichment>
    <enrichment key="THI_conferenceName">11th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOIMAGING, Funchal (Portugal), 19.-21.01.2018</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Creative Commons BY-NC-ND 4.0</licence>
    <author>
      <first_name>Marc</first_name>
      <last_name>Aubreville</last_name>
    </author>
    <editor>
      <first_name>Sheldon</first_name>
      <last_name>Wiebe</last_name>
    </editor>
    <author>
      <first_name>Miguel</first_name>
      <last_name>Goncalves</last_name>
    </author>
    <editor>
      <first_name>Hugo</first_name>
      <last_name>Gamboa</last_name>
    </editor>
    <author>
      <first_name>Christian</first_name>
      <last_name>Knipfer</last_name>
    </author>
    <editor>
      <first_name>Ana</first_name>
      <last_name>Fred</last_name>
    </editor>
    <author>
      <first_name>Nicolai</first_name>
      <last_name>Oetter</last_name>
    </author>
    <editor>
      <first_name>Sergi</first_name>
      <last_name>Bermúdez i Badia</last_name>
    </editor>
    <author>
      <first_name>Tobias</first_name>
      <last_name>Würfl</last_name>
    </author>
    <author>
      <first_name>Helmut</first_name>
      <last_name>Neumann</last_name>
    </author>
    <author>
      <first_name>Florian</first_name>
      <last_name>Stelzle</last_name>
    </author>
    <author>
      <first_name>Christopher</first_name>
      <last_name>Bohr</last_name>
    </author>
    <author>
      <first_name>Andreas</first_name>
      <last_name>Maier</last_name>
    </author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Automatic Carcinoma Detection</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Confocal Laser Endomicroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep Convolutional Networks</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Squamous Cell Carcinoma</value>
    </subject>
    <collection role="open_access" number="">open_access</collection>
    <thesisPublisher>Technische Hochschule Ingolstadt</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-haw/files/2627/65347.pdf</file>
  </doc>
  <doc>
    <id>1461</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>67</pageFirst>
    <pageLast>85</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <articleNumber/>
    <type>conferenceobject</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Cham</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-02-24</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Transferability of deep learning algorithms for malignancy detection in confocal laser endomicroscopy images from different anatomical locations of the upper gastrointestinal tract</title>
    <parentTitle language="eng">Biomedical Engineering Systems and Technologies</parentTitle>
    <identifier type="issn">1865-0929</identifier>
    <identifier type="isbn">978-3-030-29195-2</identifier>
    <identifier type="isbn">978-3-030-29196-9</identifier>
    <note>Access to this content is enabled by Nationallizenz Ebooks Medicine</note>
    <enrichment key="THI_relatedIdentifier">https://doi.org/10.1007/978-3-030-29196-9_4</enrichment>
    <enrichment key="THI_review">peer-review</enrichment>
    <enrichment key="THI_conferenceName">11th International Joint Conference, BIOSTEC 2018, Funchal (Portugal), 19.-21.01.2018</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="THI_openaccess">nein</enrichment>
    <author>
      <first_name>Marc</first_name>
      <last_name>Aubreville</last_name>
    </author>
    <author>
      <first_name>Miguel</first_name>
      <last_name>Goncalves</last_name>
    </author>
    <author>
      <first_name>Christian</first_name>
      <last_name>Knipfer</last_name>
    </author>
    <author>
      <first_name>Nicolai</first_name>
      <last_name>Oetter</last_name>
    </author>
    <author>
      <first_name>Tobias</first_name>
      <last_name>Würfl</last_name>
    </author>
    <author>
      <first_name>Helmut</first_name>
      <last_name>Neumann</last_name>
    </author>
    <author>
      <first_name>Florian</first_name>
      <last_name>Stelzle</last_name>
    </author>
    <author>
      <first_name>Christopher</first_name>
      <last_name>Bohr</last_name>
    </author>
    <author>
      <first_name>Andreas</first_name>
      <last_name>Maier</last_name>
    </author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Confocal Laser Endomicroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Transfer learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Head and neck squamous cell carcinoma</value>
    </subject>
    <collection role="institutes" number="15984">Fakultät Elektrotechnik und Informatik</collection>
    <collection role="institutes" number="19379">AImotion Bavaria</collection>
  </doc>
</export-example>
