@article{SperlSprengerTanetal.2017, author = {Sperl, Jonathan I. and Sprenger, Tim and Tan, Ek Tsoon and Menzel, Marion Irene and Hardy, Christopher J. and Marinelli, Luca}, title = {Model-based denoising in diffusion-weighted imaging using generalized spherical deconvolution}, volume = {78}, journal = {Magnetic Resonance in Medicine}, number = {6}, publisher = {Wiley}, address = {Hoboken}, issn = {1522-2594}, doi = {https://doi.org/10.1002/mrm.26626}, pages = {2428 -- 2438}, year = {2017}, language = {en} } @article{BenjaminGomezGolbabaeeetal.2019, author = {Benjamin, Arnold Julian Vinoj and G{\´o}mez, Pedro A. and Golbabaee, Mohammad and Bin Mahbub, Zaid and Sprenger, Tim and Menzel, Marion Irene and Davies, Mike E. and Marshall, Ian}, title = {Multi-shot Echo Planar Imaging for accelerated Cartesian MR Fingerprinting: An alternative to conventional spiral MR Fingerprinting}, volume = {2019}, journal = {Magnetic Resonance Imaging}, number = {61}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0730-725X}, doi = {https://doi.org/10.1016/j.mri.2019.04.014}, pages = {20 -- 32}, year = {2019}, language = {en} } @article{LacerdaSperlMenzeletal.2015, author = {Lacerda, Luis M. and Sperl, Jonathan I. and Menzel, Marion Irene and Sprenger, Tim and Barker, Gareth J. and Dell'Acqua, Flavio}, title = {Diffusion in realistic biophysical systems can lead to aliasing effects in diffusion spectrum imaging}, volume = {76}, journal = {Magnetic Resonance in Medicine}, number = {6}, publisher = {Wiley}, address = {Hoboken}, issn = {1522-2594}, doi = {https://doi.org/10.1002/mrm.26080}, pages = {1837 -- 1847}, year = {2015}, abstract = {Purpose Diffusion spectrum imaging (DSI) is an imaging technique that has been successfully applied to resolve white matter crossings in the human brain. However, its accuracy in complex microstructure environments has not been well characterized. Theory and Methods Here we have simulated different tissue configurations, sampling schemes, and processing steps to evaluate DSI performances' under realistic biophysical conditions. A novel approach to compute the orientation distribution function (ODF) has also been developed to include biophysical constraints, namely integration ranges compatible with axial fiber diffusivities. Results Performed simulations identified several DSI configurations that consistently show aliasing artifacts caused by fast diffusion components for both isotropic diffusion and fiber configurations. The proposed method for ODF computation showed some improvement in reducing such artifacts and improving the ability to resolve crossings, while keeping the quantitative nature of the ODF. Conclusion In this study, we identified an important limitation of current DSI implementations, specifically the presence of aliasing due to fast diffusion components like those from pathological tissues, which are not well characterized, and can lead to artifactual fiber reconstructions. To minimize this issue, a new way of computing the ODF was introduced, which removes most of these artifacts and offers improved angular resolution.}, language = {en} } @article{SprengerSperlFernandezetal.2016, author = {Sprenger, Tim and Sperl, Jonathan I. and Fernandez, Brice and Haase, Axel and Menzel, Marion Irene}, title = {Real valued diffusion-weighted imaging using decorrelated phase filtering}, volume = {77}, journal = {Magnetic Resonance in Medicine}, number = {2}, publisher = {Wiley}, address = {Hoboken}, issn = {1522-2594}, doi = {https://doi.org/10.1002/mrm.26138}, pages = {559 -- 570}, year = {2016}, language = {en} } @article{SprengerSperlFernandezetal.2016, author = {Sprenger, Tim and Sperl, Jonathan I. and Fernandez, Brice and Golkov, Vladimir and Eidner, Ines and S{\"a}mann, Philipp G. and Czisch, Michael and Tan, Ek Tsoon and Hardy, Christopher J. and Marinelli, Luca and Haase, Axel and Menzel, Marion Irene}, title = {Bias and precision analysis of diffusional kurtosis imaging for different acquisition schemes}, volume = {76}, journal = {Magnetic Resonance in Medicine}, number = {6}, publisher = {Wiley}, address = {Hoboken}, issn = {1522-2594}, doi = {https://doi.org/10.1002/mrm.26008}, pages = {1684 -- 1696}, year = {2016}, language = {en} }