Workflow for bioprinting of cell-laden bioink

  • Applying technologies of additive manufacturing to the field of tissue engineering created a pioneering new approach to model complex cell systems artificially. Regarding its huge potential, bioprinting is still in its infancies and many questions are still unanswered. To address this issue, an extrusion-based bioprinting (EBB) process was used to deposit human embryonic kidney (HEK) cells in a defined pattern. It was shown that the bioprinted construct featured a high degree in viability reaching up to 77% 10 days after printing (DAP). This work displays a proof of principle for a controlled cell formation which shall later be applied to in vitro drug screening tests using various types of cells.

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Metadaten
Author:Sebastian Allig, Margot Mayer, Christiane Thielemann
Parent Title (English):Lekar a technika – Clinician and Technology
Document Type:Article
Language:English
Year of Completion:2018
Release Date:2020/04/14
Tag:Extrusion-based bioprinting; bioink; in vitro cell systems; tissue engineering
GND Keyword:Biomaterial; Biomedizinische Technik
Volume:48
Issue:2
First Page:46
Last Page:51
Urheberrecht:1
Institutes:Fakultät Ingenieurwissenschaften / Labore / BIOMEMS
Licence (German):Keine Lizenz - es gilt das deutsche Urheberrecht