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  <doc>
    <id>2260</id>
    <completedYear>2024</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>11</pageLast>
    <pageNumber/>
    <edition/>
    <issue>1</issue>
    <volume>2024</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2024-03-01</completedDate>
    <publishedDate>2024-03-01</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Enzymatic Self-Degradable PLA-Based Electrets</title>
    <abstract language="eng">In recent years, the demand for sustainable and degradable materials and electronic devices has increased significantly.&#13;
Among a range of biodegradable polymers, poly(lactic acid) (PLA) is a good alternative to conventional petrol-based polymers because of its attractive mechanical properties and its easy processability. Recently, PLA has also been described as a promising dielectric material with piezoelectric and electret properties. We expect that PLA—after further optimization— will play an important role as a material for environmentally friendly sensors in the future, where first applications such as air filters and pressure sensors have already been proposed. However, degradation under normal ambient conditions is very slow, and an accelerated and controllable degradation process is highly desirable for any type of PLA-based sensors.&#13;
Enzymatic hydrolysis with embedded enzymes has been proposed as an approach to accelerate and control degradation. In this work, we investigate the properties of PLA in terms of dielectric and mechanical properties with a focus on its ability to store charges after the enzyme proteinase K (Trit. album) has been incorporated. Results reveal that proteinase K has a positive effect on the charge stability of solvent-cast PLA electrets after complete evaporation of the solvent. Furthermore, we observed a concentration-dependent acceleration of mass loss in a Tris-HCl buffer. A fast degradation within only one day occurred at a concentration of 6 wt% proteinase K.</abstract>
    <parentTitle language="eng">Journal of Polymers and the Environment</parentTitle>
    <identifier type="doi">Journal of https://doi.org/10.1007/s10924-024-03240-6</identifier>
    <enrichment key="copyright">1</enrichment>
    <enrichment key="HAB_Review">ja</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Dennis Flachs</author>
    <author>Sergey Zhukov</author>
    <author>Isabella Zech</author>
    <author>Timo Schreck</author>
    <author>Stefan Belle</author>
    <author>Heinz von Seggern</author>
    <author>Mario Kupnik</author>
    <author>Alexander Anton Altmann</author>
    <author>Christiane Thielemann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Biologisch abbaubarer Kunststoff</value>
    </subject>
    <collection role="institutes" number="">BIOMEMS Lab</collection>
    <collection role="forschungsschwerpunkte" number="">Material Testing &amp; Sensor Technology</collection>
    <file>https://opus4.kobv.de/opus4-h-ab/files/2260/s10924-024-03240-6.pdf</file>
  </doc>
  <doc>
    <id>2061</id>
    <completedYear>2022</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>2</pageLast>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>2022</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-11-17</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Characterization of electrically conductive, printable ink based on alginate hydrogel and graphene nanoplatelets</title>
    <abstract language="eng">In recent years, there has been an increasing interest in electrically conductive hydrogels for a wide range of biomedical applications, like tissue engineering or biosensors. In this study, we present a cost-effective conductive hydrogel based on alginate and graphene nanoplatelets for extrusion-based bioprinters. The hydrogel is prepared under ambient conditions avoiding high temperatures detrimental for cell culture environments. Investigation of the hydrogel revealed a conductivity of up to 7.5 S/cm, depending on the ratio of platelets. Furthermore, in vitro tests with human embyronic kidney cells - as an example cell type - showed good adhesion of the cells to the surface of the conductive hydrogel. Electrochemical measurements revealed a low electrode impedance which is desirable for the extracellular recording, but also low electrode capacitance, which is unfavorable for electrical stimulation purposes. Therefore, future experiments with the graphene nanoplatelets-based hydrogels will focus on electrodes for biosensors and extracellular recordings of neurons or cardiac myocytes.</abstract>
    <parentTitle language="eng">Biomedical Engineering Advances</parentTitle>
    <identifier type="doi">https://doi.org/10.1016/j.bea.2022.100045</identifier>
    <enrichment key="copyright">0</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Dennis Flachs</author>
    <author>Johannes Etzel</author>
    <author>Margot Mayer</author>
    <author>Frederic Harbecke</author>
    <author>Stefan Belle</author>
    <author>Tim Rickmeyer</author>
    <author>Christiane Thielemann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Hydrogel</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Biosensor</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Alginate</value>
    </subject>
    <collection role="institutes" number="">BIOMEMS Lab</collection>
    <collection role="forschungsschwerpunkte" number="">Innovative Material Processing</collection>
  </doc>
</export-example>
