@article{MoserHildenbrandMuelleretal.2016, author = {Moser, Felipe and Hildenbrand, Georg and M{\"u}ller, Patrick and Al Saroori, Alexander and Biswas, Abin and Bach, Margund and Wenz, Frederik and Cremer, Christoph and Burger, Nina and Veldwijk, Marlon R. and Hausmann, Michael}, title = {Cellular Uptake of Gold Nanoparticles and Their Behavior as Labels for Localization Microscopy}, series = {Biophysical Journal}, volume = {110}, journal = {Biophysical Journal}, number = {4}, publisher = {Elsevier BV}, issn = {0006-3495}, doi = {https://doi.org/10.1016/j.bpj.2016.01.004}, pages = {947 -- 953}, year = {2016}, subject = {Krebs, Medizin}, language = {en} } @article{BosiekHausmannHildenbrand2016, author = {Bosiek, Katharina and Hausmann, Michael and Hildenbrand, Georg}, title = {Perspectives on Comets, Comet-like Asteroids, and Their Predisposition to Provide an Environment That Is Friendly to Life}, series = {Astrobiology}, volume = {16}, journal = {Astrobiology}, number = {4}, publisher = {Mary Ann Liebert Inc}, issn = {1531-1074}, doi = {https://doi.org/10.1089/ast.2015.1354}, pages = {311 -- 323}, year = {2016}, subject = {Komet}, language = {en} } @book{PreussSchoene2016, author = {Preuß, Norbert and Sch{\"o}ne, Lars Bernhard}, title = {Real Estate und Facility Management aus Sicht der Consultingpraxis}, publisher = {Springer Vieweg}, address = {Berlin}, isbn = {978-3-662-48290-2}, doi = {10.1007/978-3-662-48291-9}, pages = {773}, year = {2016}, abstract = {Die {\"u}berarbeitete und deutlich erweiterte 4. Auflage dieses anerkannten Standardwerkes liefert einen umfassenden Einblick in die Grunds{\"a}ulen des Real Estate und Facility Managements. Von der Projektentwicklung, dem Projektmanagement, {\"u}ber das Transaktions-, Portfolio- und Risikomanagement bis hin zum Asset-, Property- und Facility Management. Alle wesentlichen Leistungen sowie Argumente f{\"u}r ein nachhaltiges Management der Sachwertanlage Immobilie, die hierf{\"u}r notwendigen Strategien, Methoden sowie Vorgehensweisen werden detailliert dargelegt. Besonders informativ, anregend und aufschlussreich wird der Leser durch den interdisziplin{\"a}ren Ansatz sowie die umfangreichen aktuellen Beispiele, Tabellen und Abbildungen durch den Lebenszyklus der Immobilie gef{\"u}hrt. Dieses Werk wendet sich seit nunmehr {\"u}ber 15 Jahren an drei Zielgruppen: Studenten, die sich mit den Grundlagen und den vertiefenden Aspekten der Bau- und Immobilienwirtschaft insgesamt oder mit einzelnen Elementen, wie etwa einer Portfolio-Analyse oder der Due Diligence, gezielt auseinandersetzen wollen; an Praktiker, die die aktuellen Entwicklungen ihres Fachgebiets verfolgen und eine fortw{\"a}hrende Aktualisierung ihres Wissenstandes anstreben sowie Wissenschaftler, die durch die kritische Reflexion der hier beschriebenen Expertisen Impulse f{\"u}r die Weiterentwicklung ihres Forschungsgebietes erhalten k{\"o}nnen.}, subject = {Facility-Management}, language = {de} } @article{SoethjeIschdonatBrauneetal.2016, author = {S{\"o}thje, Dominik and Ischdonat, Nils and Braune, Christian and Setzer, Andreas and Dreyer, Christian}, title = {Zweites Leben f{\"u}r Flugzeugkabinen - Chemisches Recycling duromerbasierter faserverst{\"a}rkter Kunststoffe}, series = {Kunststoffe}, volume = {2016}, journal = {Kunststoffe}, number = {9}, pages = {205 -- 208}, year = {2016}, subject = {Faserverst{\"a}rkter Kunststoff}, language = {de} } @article{Weithmann2016, author = {Weithmann, Sabrina}, title = {Standardization in China: Electric Vehicle Technology as Driver for Change in China's Automotive Standardization}, series = {International Journal of Standardization Research (IJSR)}, volume = {2016}, journal = {International Journal of Standardization Research (IJSR)}, number = {14 (2)}, pages = {20 -- 32}, year = {2016}, abstract = {Electric vehicle (EV) development in China emerged with the 863 program (1986) for high technologies and has received support since the 10th Five Year Plan. While standards were of no particular importance in the early years of EV development, standards have increasingly become subject to policies and programs. For instance, the promotion of 'indigenous' or 'home-grown' innovation is perceived as means to develop domestic standards and contribute to international standards. Alongside this target, the Chinese government mandated the development of an EV standardization roadmap to serve as a guideline for optimizing standardization work, promoting technical innovation and large-scale industrialization. It was even considered that EV standardization was a novel standard field that has the potential to secure China a forerunner position in technological development as well as international standardization, regardless of standard-setting practices in the conventional automotive sector. Against this background, this paper examines the differences in system set-up and processes of standardization for the traditional automotive and the electric vehicles sector. While conventional automotive standardization is limited to a single sector with the Ministry of Industry of Information Technology and the China Automotive Technology and Research Centre in charge, electric vehicles require the participation of stakeholders from other sectors. Therefore, the negative influence from the conventional decentralized automotive sector on the development of common nationwide standards like the dynamics between national, regional and local actors cannot be deprived. Additionally, this paper also highlights learnings from EV standardization that might set positive impulses for conventional EV standardizations.}, subject = {China}, language = {en} } @article{KroehnReuterHahnleetal.2016, author = {Kr{\"o}hn, Michael and Reuter, Norbert and Hahnle, Michael and Prochus, Tobias and Doll, Konrad}, title = {Gestengesteuerte Prozessanalyse}, series = {atp edition - Automatisierungstechnische Praxis}, volume = {58}, journal = {atp edition - Automatisierungstechnische Praxis}, number = {12}, pages = {26 -- 33}, year = {2016}, subject = {Prozessanalyse}, language = {de} } @inproceedings{KriniMirzaRodemer2016, author = {Krini, Mohammed and Mirza, Zafar Baig and Rodemer, Klaus}, title = {A Practical Beamformer-Postfilter System for Microphone Arrays on Seat Belts}, series = {12. ITG Symposium Speech Communication (ITG'16), Paderborn}, volume = {2016}, booktitle = {12. ITG Symposium Speech Communication (ITG'16), Paderborn}, year = {2016}, subject = {Sicherheitsgurt}, language = {en} } @article{RajanKriniSchmidt2016, author = {Rajan, Vasudev Kandade and Krini, Mohammed and Schmidt, Gerhard}, title = {Signal Processing Techniques for Seat Belt Micro-phone Arrays}, series = {EURASIP Journal on Advances in Signal Processing}, volume = {2016}, journal = {EURASIP Journal on Advances in Signal Processing}, year = {2016}, subject = {Signalverarbeitung}, language = {en} } @inproceedings{SchwarzRungHellmann2016, author = {Schwarz, Simon and Rung, Stefan and Hellmann, Ralf}, title = {Simulation of process parameters towards the generation of low spatial frequency LIPSS on dielectric materials}, series = {MultiScience - XXX. microCAD International Multidisciplinary Scientific Conference}, booktitle = {MultiScience - XXX. microCAD International Multidisciplinary Scientific Conference}, year = {2016}, subject = {Laserbestrahlung}, language = {en} } @article{AdelmannHellmann2016, author = {Adelmann, Benedikt and Hellmann, Ralf}, title = {SiC absorption of near-infrared laser radiation at high temperatures}, series = {Applied Physics A}, volume = {2016}, journal = {Applied Physics A}, number = {122}, pages = {1 -- 7}, year = {2016}, subject = {Laserbestrahlung}, language = {en} } @article{AdelmannHellmann2016, author = {Adelmann, Benedikt and Hellmann, Ralf}, title = {Numerical and experimental study on flexural strength of laser microstructured alumina}, series = {Advances in Ceramic Science and Engineering}, volume = {2016}, journal = {Advances in Ceramic Science and Engineering}, number = {5}, pages = {28 -- 34}, year = {2016}, subject = {Faserlaser}, language = {en} } @article{SchwarzRungHellmann2016, author = {Schwarz, Simon and Rung, Stefan and Hellmann, Ralf}, title = {Generation of laser-induced periodic surface structures on transparent material-fused silica}, series = {Applied Physics Letters}, volume = {108}, journal = {Applied Physics Letters}, number = {18}, pages = {181607 -- 181607}, year = {2016}, subject = {Laser}, language = {en} } @article{RothRungHellmann2016, author = {Roth, Gian-Luca and Rung, Stefan and Hellmann, Ralf}, title = {Welding of transparent polymers using femtosecond laser}, series = {Applied Physics A}, volume = {122}, journal = {Applied Physics A}, number = {2}, pages = {86 -- 90}, year = {2016}, abstract = {Based on nonlinear absorption, we report on laser welding of cycloolefin copolymers without any additional absorption layer employing infrared femtosecond laser. To the best of our knowledge, this is the first report of ultrashort laser welding of this material class, revealing a remarkable high processing speed of 20 mm/s in a single pass mode. Using a 1028 nm laser having a pulse duration of 220 fs at a repetition rate of 571 kHz leads to a welding seam width between 38 and 137 μm, depending on the applied laser average power. The welded joint is characterized by a maximum shear strength of 40 MPa. The experimental results are compared to those reported for femtosecond laser welding of PMMA and to those published for using a Thulium fiber laser.}, subject = {Femtosekundenlaser}, language = {en} } @article{SamhaberSchottdorfElHadyetal.2016, author = {Samhaber, Robert and Schottdorf, Manuel and El Hady, Ahmed and Br{\"o}king, Kai and Daus, Andreas and Thielemann, Christiane and St{\"u}hmer, Walter and Wolf, Fred}, title = {Growing neuronal islands on multi-electrode arrays using an accurate positioning-μCP device}, series = {Journal of Neuroscience Methods}, volume = {2016}, journal = {Journal of Neuroscience Methods}, number = {257}, doi = {10.1016/j.jneumeth.2015.09.022}, pages = {194 -- 203}, year = {2016}, abstract = {Background: Multi-electrode arrays (MEAs) allow non-invasive multi-unit recording in-vitro from cultured neuronal networks. For sufficient neuronal growth and adhesion on such MEAs, substrate preparation is required. Plating of dissociated neurons on a uniformly prepared MEA's surface results in the formation of spatially extended random networks with substantial inter-sample variability. Such cultures are not optimally suited to study the relationship between defined structure and dynamics in neuronal networks. To overcome these shortcomings, neurons can be cultured with pre-defined topology by spatially structured surface modification. Spatially structuring a MEA surface accurately and reproducibly with the equipment of a typical cell-culture laboratory is challenging. New method: In this paper, we present a novel approach utilizing micro-contact printing (μCP) combined with a custom-made device to accurately position patterns on MEAs with high precision. We call this technique AP-μCP (accurate positioning micro-contact printing). Comparison with existing methods: Other approaches presented in the literature using μCP for patterning either relied on facilities or techniques not readily available in a standard cell culture laboratory, or they did not specify means of precise pattern positioning. Conclusion: Here we present a relatively simple device for reproducible and precise patterning in a standard cell-culture laboratory setting. The patterned neuronal islands on MEAs provide a basis for high throughput electrophysiology to study the dynamics of single neurons and neuronal networks.}, subject = {Mehrfachelektrode}, language = {en} } @article{FlachsCiba2016, author = {Flachs, Dennis and Ciba, Manuel}, title = {Cell-based sensor chip for neurotoxicity measurements in drinking water}, series = {L{\´e}kař a technika - Clinician and Technology}, volume = {46}, journal = {L{\´e}kař a technika - Clinician and Technology}, number = {2}, pages = {46 -- 50}, year = {2016}, abstract = {Our drinking water contains residues of pharmaceuticals. A sub-group of these contaminants are neuro-active substances, the antiepileptic carbamazepine being one of the most relevant. For assessment of the neurotoxicity of this drug at a sub-therapeutic level, a cell-based sensor chip platform has been realized and characterized. For this purpose, a microelectrode array chip was designed and processed in a clean room and optimized in terms of low processing costs and good recording properties. For characterization of the system neuronal cells were plated on microelectrode array chips and electrical activity was measured as a function of applied carbamazepine concentration. We found that the relative spike rate decreased with increasing drug concentration resulted in IC50 values of around 36 μM. This value is five orders of magnitude higher than the maximal dose found in drinking water. IC50 values for burst rate, burst duration and synchrony were slightly higher, suggesting spike rate being a more sensitive parameter to carbamazepine.}, subject = {Mikroelektrode}, language = {en} } @article{OsterDausErbesetal.2016, author = {Oster, Stefan and Daus, Andreas and Erbes, Christian and Goldhammer, Michael and Bochtler, Ulrich and Thielemann, Christiane}, title = {Long-term electromagnetic exposure of developing neuronal networks: A flexible experimental setup}, series = {Bioelectromagnetics}, volume = {2016}, journal = {Bioelectromagnetics}, number = {37}, doi = {10.1002/bem.21974}, pages = {264 -- 278}, year = {2016}, abstract = {Neuronal networks in vitro are considered one of the most promising targets of research to assess potential electromagnetic field induced effects on neuronal functionality. A few exposure studies revealed there is currently no evidence of any adverse health effects caused by weak electromagnetic fields. Nevertheless, some published results are inconsistent. Particularly, doubts have been raised regarding possible athermal biological effects in the young brain during neuronal development. Therefore, we developed and characterized a flexible experimental setup based on a transverse electromagnetic waveguide, allowing controlled, reproducible exposure of developing neuronal networks in vitro. Measurement of S-parameters confirmed very good performance of the Stripline in the band of 800-1000 MHz. Simulations suggested a flexible positioning of cell culture dishes throughout a large exposure area, as specific absorption rate values were quite independent of their position (361.7 ± 11.4 mW/kg) at 1 W, 900 MHz. During exposure, thermal drift inside cellular medium did not exceed 0.1 K. Embryonic rat cortical neurons were cultivated on microelectrode array chips to non-invasively assess electrophysiological properties of electrogenic networks. Measurements were taken for several weeks, which attest to the experimental setup being a reliable system for long-term studies on developing neuronal tissue.}, subject = {Neuronales Netz}, language = {en} } @inproceedings{MayerArrizabalagaRitteretal.2016, author = {Mayer, Margot and Arrizabalaga, Onetsine and Ritter, Sylvia and Thielemann, Christiane}, title = {Human Embryonic Stem Cell Derived Neurospheres - A Novel Three Dimensional Model For Neurotoxicological Studies}, series = {Frontiers}, volume = {2016}, booktitle = {Frontiers}, number = {MEA Meeting 2016}, doi = {10.3389/conf.fnins.2016.93.00081}, year = {2016}, abstract = {At present, most neurotoxicological studies in the field of microelectrode array (MEA) technology are based on in vivo or in vitro animal models, particularly in mice or rats. These models contributed much to our knowledge about molecular and cellular mechanisms of neurotoxins affecting the central nervous system. Yet, animal models are not necessarily capable to forecasting the effectiveness of treatment in clinical trials. Therefore the development and characterization of suitable neuronal cell models derived from human cells is emerging in the field of toxicity testing. In this study, we present neurospheres (NS) as a new three dimensional (3D) neuronal cell model based on human embryonic stem cells (hESC), coupled onto microelectrode arrays (MEA). This cell-based assay serves as platform to investigate effects of neuroactive substances on network communication. In order to characterize the neurospheres' reaction, the well-known GABA receptor antagonist bicuculline and the sodium channel blocker carbamazepine are applied. Preliminary results reveal anticipated and physiologically reasonable alterations in network activity. Thus, we have the first evidence that hESC derived NS are a promising 3D cell model for neurotoxicity testing. In further studies, this model will be used to investigate effects of ionizing radiation on network signaling.}, subject = {Mikroelektrode}, language = {en} } @inproceedings{KoehlerWoelfelBochtleretal.2016, author = {K{\"o}hler, Tim and W{\"o}lfel, Maximilian and Bochtler, Ulrich and Thielemann, Christiane}, title = {TETRA specific long-term exposure of neuronal in vitro networks}, series = {BioEM2016}, booktitle = {BioEM2016}, year = {2016}, subject = {Neuronales Netz}, language = {en} } @inproceedings{KoerbitzerKraussSchneideretal.2016, author = {K{\"o}rbitzer, Berit Silke and Krauß, Peter and Schneider, J{\"o}rg and Thielemann, Christiane}, title = {Characterization Of Graphene-Coated Microelectrode Arrays For Recording And Stimulation Of Neuronal Cells}, series = {Frontiers}, volume = {2016}, booktitle = {Frontiers}, number = {MEA Meeting 2016}, doi = {10.3389/conf.fnins.2016.93.00013}, year = {2016}, subject = {Mikroelektrode}, language = {en} } @incollection{Krueger2016, author = {Kr{\"u}ger, Malte}, title = {Mobile payments: the second wave}, series = {Transforming payment systems in Europe : Palgrave Macmillan studies in banking and financial institutions}, booktitle = {Transforming payment systems in Europe : Palgrave Macmillan studies in banking and financial institutions}, editor = {G{\´o}rka, Jakub}, pages = {214 -- 235}, year = {2016}, subject = {Elektronischer Zahlungsverkehr}, language = {en} }