@article{SallumAlvesThielemannetal.2024, author = {Sallum, Loriz Francisco and Alves, Caroline and Thielemann, Christiane and Rodrigues, Francisco A.}, title = {Revealing patterns in major depressive disorder with machine learning and networks}, series = {medrxiv}, volume = {2024}, journal = {medrxiv}, number = {1}, doi = {doi.org/10.1101/2024.06.07.24308619}, pages = {1 -- 17}, year = {2024}, abstract = {Major depressive disorder (MDD) is a multifaceted condition that affects millions of people worldwide and is a leading cause of disability. There is an urgent need for an automated and objective method to detect MDD due to the limitations of traditional diagnostic approaches. In this paper, we propose a methodology based on machine and deep learning to classify patients with MDD and identify altered functional connectivity patterns from EEG data. We compare several connectivity metrics and machine learning algorithms. Complex network measures are used to identify structural brain abnormalities in MDD. Using Spearman correlation for network construction and the SVM classifier, we verify that it is possible to identify MDD patients with high accuracy, exceeding literature results. The SHAP (SHAPley Additive Explanations) summary plot highlights the importance of C4-F8 connections and also reveals dysfunction in certain brain areas and hyperconnectivity in others. Despite the lower performance of the complex network measures for the classification problem, assortativity was found to be a promising biomarker. Our findings suggest that understanding and diagnosing MDD may be aided by the use of machine learning methods and complex networks.}, subject = {Depression}, language = {en} } @article{SzewczykMoniciThielemann2024, author = {Szewczyk, Nathaniel J. and Monici, Monica and Thielemann, Christiane}, title = {How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?}, series = {npj Microgravity}, volume = {2024}, journal = {npj Microgravity}, number = {10}, doi = {DOI: 10.1038/s41526-024-00395-3}, pages = {1 -- 5}, year = {2024}, abstract = {Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, "Biology in Space and Analogue Environments", focusses in 5 main topic areas, aiming to address key community-identified knowledge gaps in Space Biology. Here we present one of the identified topic areas, which is also an unanswered question of life science research in Space: "How to Obtain an Integrated Picture of the Molecular Networks Involved in Adaptation to Microgravity in Different Biological Systems?" The manuscript reports the main gaps of knowledge which have been identified by the community in the above topic area as well as the approach the community indicates to address the gaps not yet bridged. Moreover, the relevance that these research activities might have for the space exploration programs and also for application in industrial and technological fields on Earth is briefly discussed.}, subject = {Weltraumforschung}, language = {en} } @book{Lauer, author = {Lauer, Thomas}, title = {Change Management: Grundlagen und Erfolgsfaktoren}, edition = {3., vollst{\"a}ndig {\"u}berarbeitete und erweiterte Auflage}, publisher = {Springer Gabler}, address = {Berlin}, isbn = {978-3-662-59101-7}, doi = {10.1007/978-3-662-59102-4}, subject = {Change Management}, language = {de} } @techreport{JostMink2024, type = {Working Paper}, author = {Jost, Thomas and Mink, Reimund}, title = {Central bank losses and commercial bank profits - unexpected and unfair?}, series = {IMFS Working Paper Series No. 199}, journal = {IMFS Working Paper Series No. 199}, pages = {35}, year = {2024}, abstract = {The Eurosystem and the Deutsche Bundesbank will incur substantial losses in 2023 that are likely to persist for several years. Due to the massive purchases of securities in the last 10 years, especially of government bonds, the banks' excess reserves have risen sharply. The resulting high interest payments to the banks since the turnaround in monetary poli-cy, with little income for the large-scale securities holdings, led to massive criticism. The banks were said to be making "unfair" profits as a result, while the fiscal authorities had to forego the previously customary transfers of central bank profits. Populist demands to limit bank profits by, for example, drastically increasing the minimum reserve ratios in the Eurosystem to reduce excess reserves are creating new severe problems and are neither justified nor helpful. Ultimately, the EU member states have benefited for a very long time from historically low interest rates because of the Eurosystem's extraordinary loose monetary policy and must now bear the flip side consequences of the massive expansion of central bank balance sheets during the necessary period of monetary policy normalisa-tion.}, subject = {Notenbank}, language = {en} } @misc{JostMink2024, author = {Jost, Thomas and Mink, Reimund}, title = {How to deal with the negative effects of inflated central bank balance sheets?}, organization = {SUERF}, pages = {1 -- 4}, year = {2024}, abstract = {Due to the massive purchases of securities in the last 15 years central banks incur substantial losses likely to persist for several years. On the other hand, the banking sector gains large profits from interest payments on their excess reserves holdings. Central banks and fiscal authorities must now bear the flip side consequences of their bond purchase programs. Populist demands to limit bank profits by drastically increasing minimum reserve ratios in the Eurosystem are creating new severe problems. Instead, a consistent and faster normalisation of central bank balance sheets would be desirable. Central banks should also no longer be central players in government bond markets to restore the lost boundaries between fiscal and monetary policy.}, subject = {Europ{\"a}ische Zentralbank}, language = {en} } @book{HofmannScheidler2024, author = {Hofmann, Georg Rainer and Scheidler, Percy}, title = {Chief Qualification Officer (CQO) und Weiterbildungsmentoren}, isbn = {978-3-9826305-0-2}, pages = {32}, year = {2024}, abstract = {Alte Weisheiten wie „Schuster bleib bei deinem Leisten!" oder auch „Was das H{\"a}nschen nicht lernt, das lernt der Hans nimmermehr" haben in der heutigen, sich wandelnden Arbeitswelt ihren Sinn verloren. Das bedeutet, dass sich die komplette Belegschaft lebenslang weiterbilden muss, idealerweise mit Unterst{\"u}tzung des Arbeitgebers. In der Ver{\"o}ffentlichung "Chief Qualification Officers (CQOs) und Weiterbildungsmentoren - Thesen und Argumente" wird unter anderem das paradoxe Verh{\"a}ltnis von Arbeitslosigkeit und Fachkr{\"a}ftemangel erl{\"a}utert, das Marktversagen im Weiterbildungsmarkt beschrieben und die Forderung nach einem Weiterbildungsbeauftragten (CQO) begr{\"u}ndet.}, subject = {Weiterbildung}, language = {de} } @inproceedings{SmeetsRoetzel2024, author = {Smeets, Mario and R{\"o}tzel, Peter}, title = {The Moderating Role of Non-Monetary Gamification in Reducing Algorithm Aversion in the Adoption of AI-based Decision Support Systems}, series = {ECIS - European Conference on Information Systems}, volume = {2024}, booktitle = {ECIS - European Conference on Information Systems}, number = {1}, pages = {1}, year = {2024}, abstract = {Integrating artificial intelligence (AI) into decision-making processes is key to improving organizational performance. However, trust in AI-based decision support systems (DSSs), similar to other information systems, is important for successful integration. A disruptive phenomenon, "algorithm aversion", can impede AI trust and, thus, acceptance. Although AI recommendations outperform human recommendations in different decision-making fields, individuals underweight recommendations from AI-based DSSs compared to human decision-makers due to a lack of AI trust. We conducted a lab experiment to investigate the role of AI recommendations in workplace-related tasks, first focusing on the mediating effect of AI trust and the negative impact of algorithm aversion on decision-making performance and the moderating effect of technical competence. Second, we analyzed the ability of gamification to reduce this phenomenon. We provide evidence regarding how to enhance decision-making performance when AI recommendations are deployed and identify countermeasures against algorithm aversion to facilitate the adoption of AI-based DSSs.}, subject = {K{\"u}nstliche Intelligenz}, language = {en} } @inproceedings{SauerHoppeBruhm2024, author = {Sauer, Jonas and Hoppe, Florian and Bruhm, Hartmut}, title = {Modellierung des Antriebsstrangs einer Textilmaschine zum Zweck der modellbasierten Steuerung}, series = {Tagungsband AALE 2024, 20. Konferenz}, volume = {2024}, booktitle = {Tagungsband AALE 2024, 20. Konferenz}, doi = {https://doi.org/10.33968/2024.33}, year = {2024}, abstract = {Zur Produktion von gewirkten Textilien werden mehrere Nadeln auf eine Legebarre gesetzt, die durch Servoantriebe positioniert werden. Aufgrund der erzwungenen Bewegung kann der Antriebsstrang bei hohen Drehzahlen zur Schwingung angeregt werden. Die richtige Wahl der Steuerkurven ist daher eine sehr wichtige und anspruchsvolle Aufgabe, die durch ein Antriebsstrangmodell unterst{\"u}tzt werden soll. Daf{\"u}r wird am Beispiel eines Teststands ein Modell des Antriebsstranges in MATLAB/Simulink® entwickelt. F{\"u}r das Antriebsstrangmodell m{\"u}ssen eine geeignete Modellordnung und Modellparameter gew{\"a}hlt werden. Die unbekannten Modellparameter werden durch eine Parameteridentifikation ermittelt. Mit einer Validierung wird ein geeignetes Anregungsspektrum f{\"u}r die Bestimmung der Modellordnung und die Parameteridentifikation ermittelt.}, subject = {Textilmaschine}, language = {de} } @book{LeimeisterSchumacherWenderoth2023, author = {Leimeister, Katja and Schumacher, Meike and Wenderoth, Lucia}, title = {Krisen und Auswege : Ringvorlesung im Wintersemester 2022/2023 an der TH Aschaffenburg}, editor = {Hofmann, Georg Rainer and Alm, Wolfgang}, publisher = {IMI Verlag, TH Aschaffenburg}, address = {Aschaffenburg}, organization = {TH Aschaffenburg}, isbn = {978-3-9823413-6-1}, pages = {44}, year = {2023}, abstract = {Krisen gab es schon immer. Aktuell hat sich jedoch ein ganzes Spektrum an Krisen entfaltet - es gibt politische und milit{\"a}rische Krisen, es brechen Energiem{\"a}rke und Lieferketten weg, wir sehen ganze Branchen gef{\"a}hrdet, auch die Gesundheit macht uns Sorgen, vom Klimawandel ganz zu schweigen. In den Veranstaltungen der Ringvorlesung „Krisen und Auswege", die im Wintersemester 2022/2023 stattfand, wurden Ph{\"a}nomene, Konzepte und L{\"o}sungen aus vielf{\"a}ltiger Perspektive erschlossen und damit die Komplexit{\"a}t des Gegenstands aufgezeigt. Herausforderungen f{\"u}r Unternehmen und Privatpersonen wurden identifiziert sowie der Einfluss auf technologische und organisatorische Entwicklungswege dargelegt. In dieser Publikation wurden die einzelnen Vortr{\"a}ge der Ringvorlesung von den Autorinnen zusammengefasst.}, subject = {Krise}, language = {de} } @book{AlmHofmannReuteretal.2023, author = {Alm, Wolfgang and Hofmann, Georg Rainer and Reuter, Carsten and Ruppert, Erich and Schumacher, Meike and Leimeister, Katja and Schmitt, Joachim and Wenderoth, Lucia}, title = {15 Jahre Wissenstransfer am Information Management Institut (IMI)}, organization = {TH Aschaffenburg}, isbn = {978-3-9823413-8-5}, pages = {78}, year = {2023}, abstract = {Im Sommer des Jahres 2022 hatte der Bayerische Landtag das neue Hochschulinnovationsgesetz (BayHIG) verabschiedet. Darin ist erstmals der Wissenstransfer als die dritte, neue S{\"a}ule der Hochschulaufgaben enthalten. Tats{\"a}chlich hat sich das IMI bereits seit 15 Jahren dem Wissenstransfer Hochschule - Wirtschaft verschrieben und zahlreiche Projekte mit unterschiedlichem Fokus erfolgreich durchgef{\"u}hrt. In der vorliegenden Publikation werden die bearbeiteten Themen im Wissenstransfer, die zahlreichen verschiedenen Veranstaltungsformate sowie die Drittmittelprojekte beleuchtet.}, subject = {Informationsmanagement}, language = {de} } @book{Hofmann2023, author = {Hofmann, Georg Rainer}, title = {Vertrauen als ein Verh{\"a}ltnis zwischen Menschen und Maschinen}, editor = {Alm, Wolfgang and Hofmann, Georg Rainer}, publisher = {IMI Verlag, TH Aschaffenburg}, address = {Aschaffenburg}, isbn = {978-3-9823413-7-8}, pages = {40}, year = {2023}, abstract = {Der technische Fortschritt von IT-Systemen, wie zum Beispiel der sogenannten „K{\"u}nstlichen Intelligenz" (KI) oder den „Common Data Spaces" (CDSs), bringt die Frage nach der Akzeptanz dieser Systeme mit sich. Sowohl die aktive ({\"o}konomische) Akzeptanz in Form des Erwerbs und der Nutzung, als auch die passive (soziale) Akzeptanz in Form der Duldung der aktiven Nutzung durch Dritte, sind f{\"u}r den Erfolg von IT-Systemen ausschlaggebend. Eine geringe Akzeptanz der Systeme und ein mangelndes Vertrauen in dieselben wird in einen Zusammenhang gebracht: Man fragt nach der Gestaltung „zuverl{\"a}ssiger und vertrauensw{\"u}rdiger Systeme", da diese besonders akzeptiert werden. In diesem Beitrag werden „Vertrauen" und dessen Zusammenhang mit „Zuverl{\"a}ssigkeit" und „Verstehen" im Kontext von IT-Systemen er{\"o}rtert.}, subject = {K{\"u}nstliche Intelligenz}, language = {de} } @article{LutzHelmTschirpkeetal.2023, author = {Lutz, Christian and Helm, Jonas and Tschirpke, Katrin and Esen, Cemal and Hellmann, Ralf}, title = {Drilling Sequence Optimization Using Evolutionary Algorithms to Reduce Heat Accumulation for Femtosecond Laser Drilling with Multi-Spot Beam Profiles}, series = {MDPI Materials}, volume = {2023}, journal = {MDPI Materials}, number = {16/5775}, doi = {10.3390/ma16175775}, pages = {1 -- 12}, year = {2023}, abstract = {We report on laser drilling borehole arrays using ultrashort pulsed lasers with a particular focus on reducing the inadvertent heat accumulation across the workpiece by optimizing the drilling sequence. For the optimization, evolutionary algorithms are used and their results are verified by thermal simulation using Comsol and experimentally evaluated using a thermal imaging camera. To enhance process efficiency in terms of boreholes drilled per second, multi-spot approaches are employed using a spatial light modulator. However, as higher temperatures occur across the workpiece when using simultaneous multi-spot drilling as compared to a single-spot process, a subtle spatial distribution and sequence of the multi-spot approach has to be selected in order to limit the resulting local heat input over the processing time. Different optimization approaches based on evolutionary algorithms aid to select those drilling sequences which allow for the combination of a high efficiency of multi-spot profiles, a low-generated process temperature and a high-component quality. In particular, using a 4 x 4 laser spot array allows for the drilling of 40,000 boreholes in less than 76 s (526 boreholes/s) with a reduced temperature increase by about 35\%, as compared to a single spot process when employing an optimized drilling sequence.}, subject = {Laserbohren}, language = {en} } @article{LutzSchwarzMarxetal.2023, author = {Lutz, Christian and Schwarz, Simon and Marx, Jan and Esen, Cemal and Hellmann, Ralf}, title = {Multi-Bessel Beams Generated by an Axicon and a Spatial Light Modulator for Drilling Applications}, series = {MDPI Photonics}, volume = {2023}, journal = {MDPI Photonics}, number = {10/413}, doi = {10.3390/photonics10040413}, pages = {1 -- 9}, year = {2023}, abstract = {We report on an optical setup to generate multi-Bessel beam profiles combining a refractive axicon and a spatial light modulator. Based on their particular beam profile, Bessel beams offer advantageous properties for micro drilling processes and internal volume processing, especially for transparent materials. In addition, the laser power of industrial, ultrashort pulsed lasers has increased significantly over the last few years, offering the possibility for highly efficient processes using multi-spot profiles. Our optical concept combines the dynamic possibilities of beam splitting using a spatial light modulator with the benefits of Bessel beams, which facilitates multi-Bessel beam processing. Beside the simulation and experimental evaluation of the generated multi-Bessel beams, we exemplify the applicability of the developed module for the perforation of thin metal foils by micro drilling.}, subject = {Bessel-B{\"u}ndel}, language = {en} } @article{SommerEsenHellmann2023, author = {Sommer, David and Esen, Cemal and Hellmann, Ralf}, title = {Static and Dynamic Mechanical Behaviour of Hybrid-PBF-LB/M-Built and Hot Isostatic Pressed Lattice Structures}, series = {Mechanical Properties of Polymeric, Metallic, and Composite Materials}, volume = {16}, journal = {Mechanical Properties of Polymeric, Metallic, and Composite Materials}, number = {9}, doi = {https://doi.org/10.3390/ma16093556}, pages = {1 -- 14}, year = {2023}, abstract = {We report on a comprehensive study of the mechanical properties of maraging steel body-centred cubic lattice structures fabricated by a hybrid additive manufacturing technology that combines laser powder bed fusion with in situ high-speed milling. As the mechanical properties of additive manufactured components are inferior to, e.g., cast components, surface modifications can improve the mechanical behaviour. Different hybrid additive manufacturing technologies have been designed using additive and subtractive processes, improving process quality. Following this, mechanical testing is performed with respect to static tensile properties and dynamic stress, hardness, and porosity, comparing specimens manufactured by laser powder bed fusion only to those manufactured by the hybrid approach. In addition, the influence of different heat-treatment techniques on the mechanical behaviour of the lattice structures is investigated, namely solution and aging treatment as well as hot isostatic pressing. Thus, the influence of the superior surface quality due to the hybrid approach is evaluated, leading to, e.g., an offset of about 14-16\% for the static testing of HIP lattice structures. Furthermore, the dynamic load behaviour can be improved with a finished surface, heading to a shift of the different zones of fatigue behaviour in the testing of hybrid-built specimens.}, subject = {Isostatisches Heißpressen}, language = {de} } @inproceedings{MarxEsenLutzetal.2023, author = {Marx, Jan and Esen, Cemal and Lutz, Christian and Hellmann, Ralf and Ostendorf, Andreas}, title = {Holographic tuning of physical axicons}, volume = {2023}, number = {154}, publisher = {LiM 2023 Proceedings}, pages = {1 -- 9}, year = {2023}, abstract = {Axicon generated Bessel beams are a popular tool for high aspect ratio precision laser drilling. Spot diameter and working distance are given by the geometric parameters of the axicon and the wavelength used. Thus, it is difficult to manipulate the beam shape of a Bessel beam for a given setup. Spatial light modulators (SLMs) overcome limitations in flexibility. However, due to the limited phase shift of SLMs, only Bessel beams with flat cone angles and large focal length can be generated. In this contribution, an approach for generating Bessel beams with a shorter, but tunable focal length is presented. A physical axicon was combined with an SLM. A holographic image of a negative axicon is put on the SLM to generate a ring beam, which is focused by a subsequent physical axicon to get a small focal diameter. Thus, different sized high aspect ratio micro holes can be drilled without using any moving components.}, subject = {Bessel-B{\"u}ndel}, language = {en} } @article{FlachsZhukovZechetal.2024, author = {Flachs, Dennis and Zhukov, Sergey and Zech, Isabella and Schreck, Timo and Belle, Stefan and von Seggern, Heiinz and Kupnik, Mario and Altmann, Alexander Anton and Thielemann, Christiane}, title = {Enzymatic Self-Degradable PLA-Based Electrets}, series = {Journal of Polymers and the Environment}, volume = {2024}, journal = {Journal of Polymers and the Environment}, number = {1}, doi = {Journal of https://doi.org/10.1007/s10924-024-03240-6}, pages = {1 -- 11}, year = {2024}, abstract = {In recent years, the demand for sustainable and degradable materials and electronic devices has increased significantly. Among a range of biodegradable polymers, poly(lactic acid) (PLA) is a good alternative to conventional petrol-based polymers because of its attractive mechanical properties and its easy processability. Recently, PLA has also been described as a promising dielectric material with piezoelectric and electret properties. We expect that PLA—after further optimization— will play an important role as a material for environmentally friendly sensors in the future, where first applications such as air filters and pressure sensors have already been proposed. However, degradation under normal ambient conditions is very slow, and an accelerated and controllable degradation process is highly desirable for any type of PLA-based sensors. Enzymatic hydrolysis with embedded enzymes has been proposed as an approach to accelerate and control degradation. In this work, we investigate the properties of PLA in terms of dielectric and mechanical properties with a focus on its ability to store charges after the enzyme proteinase K (Trit. album) has been incorporated. Results reveal that proteinase K has a positive effect on the charge stability of solvent-cast PLA electrets after complete evaporation of the solvent. Furthermore, we observed a concentration-dependent acceleration of mass loss in a Tris-HCl buffer. A fast degradation within only one day occurred at a concentration of 6 wt\% proteinase K.}, subject = {Biologisch abbaubarer Kunststoff}, language = {en} } @inproceedings{SauerGorksSpielmannetal.2023, author = {Sauer, Timm and Gorks, Manuel and Spielmann, Luca and Hepp, Nils and Zindler, Klaus and Jumar, Ulrich}, title = {AI-based control approaches for lateral vehicle guidance of industrial trucks}, series = {IFAC WC 2023 - The 22nd World Congress of the International Federation of Automatic Control 2023, Yokohama, Japan, 09.07.2023 - 14.07.2023}, booktitle = {IFAC WC 2023 - The 22nd World Congress of the International Federation of Automatic Control 2023, Yokohama, Japan, 09.07.2023 - 14.07.2023}, doi = {https://doi.org/10.1016/j.ifacol.2023.10.1501.}, year = {2023}, abstract = {Two different control concepts for the automatic track guidance of forklifts are proposed. Both approaches are based on Reinforcement Learning (RL), a method of Artificial Intelligence (AI), and are able to take into account time-variant parameters, such as the vehicle velocity, and to reduce the influence of the path curvature, the most important disturbance variable of lateral vehicle control. In the first approach, both, the path curvature and the vehicle velocity signal, are provided to the controller in addition to the state variables of the controlled system. By varying the corresponding parameters in the training process, both signals can be considered and the control parameters can be optimized accordingly. In the second approach, several controllers (multi-model concept) considering the path curvature are used and the varying vehicle velocity is taken into account using a gain-scheduling concept. Considering time-variant vehicle parameters and the influence of the disturbance variable during operation, a stable track guidance is guaranteed within the whole speed range of the industrial trucks.}, subject = {Flurf{\"o}rderer}, language = {en} } @article{BalleisWagner1998, author = {Balleis, Kristina and Wagner, Stefan}, title = {Haftung f{\"u}r Wildsch{\"a}den in gemeinschaftlichen Jagdbezirken}, series = {Zeitschrift f{\"u}r Jagdwissenschaft}, volume = {44}, journal = {Zeitschrift f{\"u}r Jagdwissenschaft}, number = {Juni}, pages = {85 -- 93}, year = {1998}, subject = {Jagdrecht}, language = {de} } @article{Balleis2000, author = {Balleis, Kristina}, title = {Keine Heilbarkeit eines Mangels unzureichender interkommunaler Abstimmung im erg{\"a}nzenden Verfahren nach \S215 a BauGB, Urteilsbesprechung}, series = {Verwaltungsrecht f{\"u}r die Anwaltspraxis}, volume = {2000}, journal = {Verwaltungsrecht f{\"u}r die Anwaltspraxis}, number = {6}, pages = {192 -- 192}, year = {2000}, subject = {Deutschland, Baugesetzbuch}, language = {de} } @article{Balleis2000, author = {Balleis, Kristina}, title = {Rechtswidrigkeit einer Vorkaufssatzung zur Sicherung st{\"a}dtebaulicher Entwicklung, Urteilsbesprechung}, series = {Verwaltungsrecht f{\"u}r die Anwaltspraxis}, volume = {2000}, journal = {Verwaltungsrecht f{\"u}r die Anwaltspraxis}, number = {5}, pages = {155 -- 155}, year = {2000}, subject = {Stadtentwicklung}, language = {de} }