@article{BeckSchraderTetzlaffetal.2018, author = {Beck, Eberhard and Schrader, Thomas and Tetzlaff, Laura and Schr{\"o}der, Cornelia}, title = {Prospektive Risikoanalyse: Die {\"A}hnlichkeit von Medikamentennamen in der Drugbank-Datenbank}, series = {GMS Medizinische Informatik, Biometrie und Epidemiologie}, volume = {14}, journal = {GMS Medizinische Informatik, Biometrie und Epidemiologie}, number = {2}, doi = {10.3205/mibe000187}, pages = {1/7 -- 7/7}, year = {2018}, language = {de} } @article{BeckRoedigerLiefoldetal.2018, author = {Beck, Eberhard and R{\"o}diger, Stefan and Liefold, Marius and Ruhe, Madeleine and Reinwald, Mark and Deckert, P. Markus}, title = {Quantification of DNA double-strand breaks in peripheral blood mononuclear cells from healthy donors exposed to bendamustine by an automated γH2AX assay—an exploratory study}, series = {Journal of Laboratory and Precision Medicine}, volume = {3}, journal = {Journal of Laboratory and Precision Medicine}, number = {5}, doi = {10.21037/jlpm.2018.04.10}, pages = {47-12}, year = {2018}, language = {en} } @article{SchwarzSchwarzCreutzburg2020, author = {Schwarz, Franziska and Schwarz, Klaus and Creutzburg, Reiner}, title = {Security and Privacy Investigation of Wi-Fi Connected and App-Controlled IoT-Based Consumer Market Smart Light Bulbs}, series = {Electronic Imaging}, journal = {Electronic Imaging}, publisher = {Society for Imaging Science and Technology}, address = {Springfield, VA}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2020.3.MOBMU-275}, pages = {275-1 -- 275-11}, year = {2020}, language = {en} } @article{PrinzOrlowskiBecketal.2025, author = {Prinz, Alexander and Orlowski, Katja and Beck, Eberhard and Witte, Kerstin}, title = {Serious Games for Seniors With Dementia: A Pilot Study}, series = {Journal of Applied Gerontology}, volume = {2025}, journal = {Journal of Applied Gerontology}, publisher = {SAGE}, doi = {10.1177/07334648251350846}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:522-opus4-33440}, pages = {1 -- 11}, year = {2025}, abstract = {Dementia, marked by cognitive decline, significantly impacts daily life. With global prevalence rising, traditional treatments manage symptoms but have side effects and offer no cure. Non-pharmacological interventions, like serious games, are gaining importance. This study assesses the feasibility and benefits of serious games for people with mild to moderate dementia over a 10-week intervention. Sixty-one patients were recruited, with 35 completing the study. The intervention included six games focusing on physical and cognitive training. Outcome measures were motor function, cognitive assessments, quality of life, and depression. Results showed significant improvements in dynamic balance (p = .013) but no significant changes in other measures. The findings suggest that serious games are feasible and can improve motor functions like balance. However, short intervention periods may limit their impact on cognitive function and quality of life. Longer interventions and personalized game designs are recommended for greater benefits.}, language = {en} } @article{KhuntsariaGachechiladzeLipartaetal.2025, author = {Khuntsaria, Irakli and Gachechiladze, Konstantine and Liparta, Elene and Kobulashvili, Tamar and Jorbenadze, Mariam and Revazishvili, Tamaz and Mamiseishvili, Ana and Kekelia, Elene and Topuridze, Marina and Sturua, Lela and Schrader, Thomas and Kldiashvili, Ekaterina}, title = {Strategic implementation of HPV vaccination to eliminate cervical cancer in Georgia}, series = {Public Health in Practice}, volume = {2025}, journal = {Public Health in Practice}, number = {10}, publisher = {Elsevier}, doi = {10.1016/j.puhip.2025.100679}, pages = {1 -- 4}, year = {2025}, abstract = {Objectives Human Papillomavirus (HPV) is a prevalent sexually transmitted infection and a leading cause of cervical cancer. In Georgia, cervical cancer ranks as the fifth most common cancer among women, with approximately 330 new cases and 200 deaths reported annually. Despite the availability of effective HPV vaccines, national vaccination coverage remains low. This study aimed to evaluate HPV vaccination coverage, analyze cervical cancer incidence trends, and model the potential impact of increased vaccination uptake on cancer prevention outcomes in Georgia. Study design A retrospective observational study was conducted using national health registry data and modeling projections to assess the burden of cervical cancer and estimate the effect of scaled vaccination coverage. Methods National health databases were used to analyze HPV vaccination rates and cervical cancer incidence. Descriptive statistics, chi-square tests, and linear regression were applied to identify trends and disparities. Additionally, a dynamic transmission model was developed to simulate the 10-year impact of increasing HPV vaccination coverage on cervical cancer incidence. Results The crude cervical cancer incidence rate was 15.7 per 100,000 women, with an age-standardized rate of 10.6 per 100,000. In 2022, only 38 \% of eligible girls aged 13-18 received the first HPV vaccine dose, and 26 \% completed the second dose. Regional disparities in vaccination and screening were noted, and overall screening coverage declined to 13,890 women screened in 2022. Modeling showed that increasing vaccine coverage to 60 \% could reduce cervical cancer incidence by 50 \% (preventing ∼163 cases); coverage of 80 \% and 90 \% could reduce incidence by 70 \% and 85 \%, preventing 228 and 276 cases, respectively. Conclusion Low HPV vaccination uptake in Georgia (38 \% first dose and 26 \% dull coverage) and declining screening limit cervical cancer prevention. Modeling shows that increasing vaccination coverage to 60-90 \% could prevent 163-276 cases over the next decade. Strengthening vaccination and screening strategies is essential to move forward elimination.}, language = {en} } @article{SteinPilgermannSedlmayr2025, author = {Stein, Stefan and Pilgermann, Michael and Sedlmayr, Martin}, title = {Systematic Evaluation of Manufacturer Disclosure Statements for Medical Device Security (MDS2) to Strengthen Hospital OT Security Measures - Lessons Learned}, series = {Studies in health technology and informatics}, volume = {331}, journal = {Studies in health technology and informatics}, doi = {10.3233/SHTI251404}, pages = {256 -- 264}, year = {2025}, abstract = {The growing number of connected medical devices in hospitals poses serious operational technology (OT) security challenges. Effective countermeasures require a structured analysis of the communication interfaces and security configurations of individual devices. State of the art: Although Manufacturer Disclosure Statements for Medical Device Security (MDS2, Version 2019) offer relevant information, they are rarely integrated into cybersecurity workflows. Existing studies are limited in scope and lack scalable methodologies for systematic evaluation. Concept: This study analyzed 209 MDS2 documents and 161 security white papers to extract structured information on ports, protocols, and protective measures. Over 52,000 question-answer pairs were converted into a machine-readable format using customized parsing and validation routines. The aim was to establish whether this dataset could inform risk assessments and future applications involving Large Language Models (LLMs). Implementation: The analysis revealed 367 distinct ports, including common protocols such as HTTPS (443), DICOM (104), and RDP (3389), as well as vendor-specific proprietary ports. Approximately 40\% of the devices used over 20 ports, indicating a broad attack surface. OCR errors and inconsistent formatting required manual corrections. A consolidated dataset was developed to support clustering, comparison across vendors and versions, and preparation for downstream LLM use, particularly via structured SBOM and configuration data. Lessons learned: Although no model training was conducted, the structured dataset can support AI-based OT security workflows. The findings highlight the critical need for up-to-date, machine-readable manufacturer data in standardized formats and schemas. Such information could greatly enhance the automation, comparability, and scalability of hospital cybersecurity measures.}, language = {en} } @article{IslamPatilRafajlovskietal.2021, author = {Islam, Saiful and Patil, Sanket Shrikant and Rafajlovski, Goran and Hartmann, Michael and Creutzburg, Reiner}, title = {Technical design and operational control of a decentralized microgrid in rural area}, series = {Electronic Imaging}, journal = {Electronic Imaging}, publisher = {Society for Imaging Science and Technology}, address = {Springfield, VA}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2021.3.MOBMU-097}, pages = {97-1 -- 97-7}, year = {2021}, language = {en} } @article{BasseyRojekHartmannetal.2021, author = {Bassey, Uduak and Rojek, Lukasz and Hartmann, Michael and Creutzburg, Reiner and Volland, Arne}, title = {The potential of NIR spectroscopy in the separation of plastics for pyrolysis}, series = {Electronic Imaging}, journal = {Electronic Imaging}, publisher = {Society for Imaging Science and Technology}, address = {Springfield, VA}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2021.3.MOBMU-143}, pages = {143-1 -- 143-14}, year = {2021}, language = {en} } @article{PilgermannWerthCreutzburg2020, author = {Pilgermann, Michael and Werth, S{\"o}ren and Creutzburg, Reiner}, title = {Towards sector specific security operation}, series = {Electronic Imaging}, journal = {Electronic Imaging}, publisher = {Society for Imaging Science and Technology}, address = {Springfield, VA}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2020.3.MOBMU-254}, pages = {254-1 -- 254-10}, year = {2020}, language = {en} } @article{HascheBenningCreutzburg2020, author = {Hasche, Eberhard and Benning, Dominik and Creutzburg, Reiner}, title = {Using ACES Look Modification Transforms (LMTs) in a Visual Effects Production Environment -Part 1: Rec.709 Inputsand Outputs}, series = {Electronic Imaging}, journal = {Electronic Imaging}, publisher = {Society for Imaging Science and Technology}, address = {Springfield, VA}, issn = {2470-1173}, doi = {10.2352/ISSN.2470-1173.2020.3.MOBMU-205}, pages = {205-1 -- 205-14}, year = {2020}, language = {en} }