@phdthesis{Efremenko2025, author = {Efremenko, Julia}, title = {Development of a new sensing technology and chemosensitive material for affinity sensors based on conducting polymers}, doi = {10.26127/BTUOpen-7012}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:co1-opus4-70123}, school = {BTU Cottbus - Senftenberg}, year = {2025}, abstract = {The work is focused on the further development of chemical sensors based on conducting polymers. The particular objectives include: (i) implementation of a novel concept for chemical sensors based on the electrical control of the affinity of a receptor layer; (ii) development of a new chemosensitive polymer for the detection of glucose and other diol-containing compounds; (iii) the elaboration of the electrochemical deposition of conducting polymers on a non-metallic plasmonic support. The first task involves the exploitation of the redox activity of conducting polymers, whereby each redox state exhibits distinct affinity properties. This principle was realized on the base of integrated electrochemical transistor comprising a conducting polymer as a receptor layer deposited onto four measurement electrodes, which were wired to the Ag/AgCl electrode through a chloride-containing ionic liquid. This additional electrode was used to control the redox state of the conducting polymer. It was demonstrated that the sensor exhibited an electrically switchable affinity to trimethylamine. This approach was applied to develop a novel chemosensing concept: a virtual sensor array comprising only a single chemosensitive element. The concept was applied in the development of a chemical sensor for the analysis of fish freshness. The second task is concerned with the electrochemical synthesis and analysis of the analytical properties of a novel chemosensitive material, poly-3-thienylboronic acid. This polymer can be synthesized as a film on the surface, as a free-standing polymer film or as polymeric nanoparticles. The presence of the boronic acid group makes it sensitive to saccharides and other compounds containing diols. The use of an adhesive self-assembled monolayer resulted in the formation of highly stable, thin polymer films on the gold electrodes. The formed polymer exhibited conductive properties, while the binding of compounds containing diols resulted in a significant increase in resistance. The affinity of this novel material to a range of different compounds was studied at varying pH and electrode potentials and compared to the affinity of its monomer. It was demonstrated that poly-3-thienylboronic acid has a high affinity for glucose. The measurements performed in a solution containing the main component of human serum indicate that this sensor may have potential applications in the medical field. The third task includes the electrochemical deposition of various conducting polymers, including poly-3-thienylboronic acid, on the surface of titanium nitride and plasmonic nanohole structures based on this material. The modes of the electrochemical polymer deposition and polymer pretreatment required for the electrochemical deposition and analysis were optimized. The research results are important for developing affinity sensors that utilize conducting polymers as chemosensitive receptor layers.}, subject = {Electrically driven affinity control; Affinity sensors; Conducting polymers; Chemotransistor; Leitf{\"a}hige Polymere; Affinit{\"a}tssensoren; Chemischer Transistor; Elektrisch angetriebene Affinit{\"a}tskontrolle; Chemischer Sensor; Biosensor; Glucose-Sensor; Leitf{\"a}hige Polymere; Redoxpolymere}, language = {en} }