Ever fiercer competition has forced enterprises not only to optimize their own operations but also to cooperate with their suppliers and customers along their supply chains. Thus, competition today usually takes place between supply chains and not between individual enterprises. Business-To-Business integration (B2Bi) is a major task of supply chain management (SCM), and although it already has been researched for years, B2Bi is still an area of active research with a plethora of research questions and according approaches. Hence, management of B2Bi projects necessitates the identification of relevant requirements which is a far from trivial task. This paper identifies a core set of B2Bi challenges and deduces a comprehensive set of B2Bi requirements that are particularly useful for tackling the challenges identified. The derivation of B2Bi requirements follows an inductive approach that is based on the analysis of integration standards, reference architectures and related literature. In order to operationalize the B2Bi requirements for further analysis and concrete B2Bi projects, the requirements are classified according to the abstraction layers of a B2Bi schema. Thus, this report not only offers a requirements check list for B2Bi projects but also helps in deciding when to address which requirements during the course of a B2Bi project.