Analytische Chemie
Filtern
Erscheinungsjahr
- 2015 (121) (entfernen)
Dokumenttyp
Schlagworte
- Prozessanalytik (9)
- Process analytical technology (7)
- Reaction monitoring (5)
- Concrete (4)
- Ground penetrating radar (4)
- Metrology (4)
- Online NMR spectroscopy (4)
- PFOS (4)
- Quantitative NMR-Spektroskopie (4)
- qNMR (4)
- Environment (3)
- Fluorescence (3)
- LIBS (3)
- Online NMR Spectroscopy (3)
- PFOA (3)
- Process Analytical Technology (3)
- Prozess-Spektroskopie (3)
- Raman spectroscopy (3)
- Reference material (3)
- Simulation (3)
- Smart Sensors (3)
- Soil (3)
- Transmission (3)
- XPS (3)
- Bisphenol A degradation (2)
- CRM (2)
- Chlorides (2)
- Crosshole (2)
- Downhole (2)
- Electron backscatter diffraction (2)
- Embedded sensors (2)
- Haftfestigkeit (2)
- Heavy metal (2)
- Hydroformylation (2)
- Industrie 4.0 (2)
- Jet grout (2)
- Microarray (2)
- Monitoring (2)
- Nanocatalysts (2)
- Nanomaterial (2)
- Nanoparticle (2)
- Nanoparticles (2)
- Orientation mapping (2)
- Prefabricated wall (2)
- Prozess-Sensoren (2)
- Quantum yield (2)
- Reflection (2)
- Reinforced concrete (2)
- Smarte Sensoren (2)
- TiO2 (2)
- Toxic metals (2)
- Ultrasonic (2)
- Ultrasound (2)
- Void detection (2)
- Wastewater (2)
- X-ray diffraction (2)
- XRF (2)
- Zentrifugentechnologie (2)
- 19F-NMR (1)
- 1H-NMR (1)
- 2D-map (1)
- 3D Reconstruction (1)
- 3D Rekonstruktion (1)
- AFM (1)
- API molecule (1)
- ASR (1)
- Absolute Isotopenverhältnisse (1)
- Absorption (1)
- Acidity (1)
- Acoustic emission (1)
- Acoustic test (1)
- Adsorption of pyridine (1)
- Advanced process control (1)
- Aggregate scattering (1)
- Air-coupled (1)
- Alkalis (1)
- Amino acid (1)
- Analyses of inks (1)
- Analytical quality assurance (1)
- Applikationslabor (1)
- Aqueous solution (1)
- Archäologie (1)
- Arzneimittelrückstände in Oberflächenwasserproben (1)
- Asymmetric flow filed-flow fractionation (1)
- BAMline (1)
- BODIPY-Farbstoffe (1)
- BONARES (1)
- Baustoffe (1)
- Baustoffuntersuchungen (1)
- Bearing steel (1)
- Belastungsversuch (1)
- Benchtop NMR Spectroscopy (1)
- Beschichtungen (1)
- Biological structure (1)
- Biozidanalytik (1)
- Blitzthermografie (1)
- Boden (1)
- Bodenfruchtbarkeit (1)
- Brennfleckgröße (1)
- CCS (1)
- CGHE (1)
- CO2 (1)
- CONSENS (1)
- Cadmium (1)
- Carbamazepin (1)
- Carbon dioxide (1)
- Carbon nanotube CNT (1)
- Carbonation (1)
- Catalysis (1)
- Catalytic wet peroxide oxidation (1)
- Cement (1)
- Characterization (1)
- Characterization method (1)
- Chemical analysis (1)
- Chemical sensors (1)
- Chemometrics (1)
- Chemometrie (1)
- Chloride (1)
- Civil engineering (1)
- Clinical diagnostics (1)
- Clustering (1)
- Coda wave interferometry (1)
- Coincidence (1)
- Commercial acoustic devices (1)
- Computersimulation (1)
- Computertomographie (1)
- Concrete condition monitoring (1)
- Concrete evaluation (1)
- Concrete specimens (1)
- Contrast agent (1)
- Coordination polymers (1)
- Cordierite (1)
- Corrosion (1)
- Crack depth (1)
- Cracks (1)
- Crystal lattice (1)
- DFG (1)
- DNA (1)
- DNA origami (1)
- Damages (1)
- Data base (1)
- Data fusion (1)
- Dauerhaftigkeit (1)
- Diameter (1)
- Diesel particulate filter (1)
- Digital image catalogues (1)
- Diutan gum (1)
- Doktorandentagung (1)
- Dosisleistung (1)
- Dye (1)
- Düngemittelgewinnung (1)
- EBSD (1)
- EBSD pattern (1)
- EC definition (1)
- EU Definition of nanomaterial (1)
- Eignungsprüfung (1)
- Einkoppeleffizienz (1)
- Einzelmolekülmagnete (1)
- Eisen (1)
- Electron Rutherford backscattering (1)
- Elektrochemie (1)
- Elementanalyse (1)
- Emissionsmesskammer (1)
- Emulsions (1)
- Emuslions (1)
- Energiekopplung (1)
- Enriched isotope (1)
- Ermüdung (1)
- Estrogen receptor (ER) (1)
- Estrone (1)
- Extinction coefficient (1)
- FD (1)
- FRET (1)
- Fenton oxidation (1)
- Fermentation (1)
- Ferroelectret (1)
- Flow profiles (1)
- Fluor-Substitution (1)
- Fluorescence Imaging (1)
- Fluorescence label (1)
- Fluorescence labeling (1)
- Fluorescence lifetime (1)
- Fluoreszenz (1)
- Fluoride catalyst (1)
- Focusing (1)
- Fügefestigkeit (1)
- Gas calibration (1)
- Gassensor (1)
- Gasspeicher (1)
- Gene-5 protein (1)
- Geographic differentiation (1)
- Geophysics (1)
- Gesamtcyanid (1)
- Gesteuerte Materialien (1)
- Gold-Katalyse (1)
- Granulated blast furnace slag (1)
- Granulierte Hochofenschlacke (1)
- HPLC (1)
- HPLC-MS/MS (1)
- HPLC/MS/MS technique (1)
- Heterogeneity (1)
- High throughput (1)
- High voltage cable accessories (1)
- Honeycombing (1)
- Hybridoma (1)
- ICP-MS (1)
- IDMS (1)
- Image processing (1)
- Imaging (1)
- Indirect Hard Modeling (IHM) (1)
- Infrared spectroscopy (1)
- Initial hydration (1)
- Inspection of CFRP (1)
- Iron (1)
- Iron-gall ink (1)
- Karak Castle (1)
- Kikuchi diffraction (1)
- Kikuchi pattern (1)
- Klebverbindungen (1)
- Kolloquium Prozessanalytik (1)
- Konvektion (1)
- Koordinationspolymere (1)
- LC-ELISA (1)
- Ladder sequencing (1)
- Laminografie (1)
- Laminography (1)
- Laser-induced breakdown spectroscopy (LIBS) (1)
- Lattice parameter determination (1)
- Lubricated contact (1)
- Luminescence (1)
- MALDI-TOF-MS (1)
- MKW (1)
- Machine learning (1)
- Massenspektrometrie (1)
- Materials characterization (1)
- Matrix effects (1)
- Mehr-Proben-Prüfung (1)
- Mehr-Proben-Prüfverfahren (1)
- Merrifield (1)
- Mesoporöse Träger (1)
- Messsysteme (1)
- Metal ions (1)
- Metal matrix (1)
- Metall (1)
- Metrologie (1)
- MicroRNA (1)
- Microcracking (1)
- Micromechanical differential scheme (1)
- Microplastics (1)
- Mikroplastik (1)
- Misindexing (1)
- Mitigation (1)
- Mo (1)
- Mobiles LIBS (1)
- Molar extinction coefficient determination (1)
- Molecular dynamics simulation (1)
- Molecular machines (1)
- Monoclonal antibodies (1)
- Multiplexing (1)
- Multivariate classification (1)
- Mycoplasma (1)
- Mycotoxins (1)
- NDT (1)
- NEXAFS (1)
- NHS (1)
- NHS-Ester (1)
- NMR-Spektroskopie (1)
- Nanoanalytic (1)
- Nanoscale EDX analysis (1)
- Nanoscale T-SEM (1)
- Natrium (1)
- Near infrared spectroscopy (1)
- Non-destructive testing (1)
- Non-metal determination (1)
- Nondestructive testing (1)
- Nuclear structures (1)
- OBOC library (1)
- Online monitoring (1)
- Online-RFA (1)
- Ophthalmische Schichten (1)
- Optical sensors (1)
- Optische Schichten (1)
- Organic osmolytes (1)
- Orientation noise (1)
- Orientation precision (1)
- PAH (1)
- PAK (1)
- PFA (1)
- PLS-R (1)
- Palimpsests (1)
- Palladium (1)
- Partial discharge (1)
- Particle (1)
- Pattern matching (1)
- Peptide (1)
- Peptide synthesis (1)
- Phase analysis (1)
- Photo-Fenton oxidation (1)
- Photostabilität (1)
- Pigments (1)
- Plasma-Injektion (1)
- Plasma-kompatible Partikel (1)
- Plasmonics (1)
- Platinum (1)
- Polycarboxylate ether (1)
- Polymer beads (1)
- Polymer optical fiber POF (1)
- Polymers (1)
- Polyoxometalates (1)
- Polysaccharides (1)
- Polyvinyl alcohol (1)
- Porosity (1)
- Portland cement (1)
- Powder diffraction (1)
- Primary standards (1)
- Primäres Isotopenreferenzmaterial (1)
- Priority pollutants (1)
- Priority substances (1)
- Process control (1)
- Proficiency testing (1)
- Prozess-Sensoren 4.0 (1)
- Prozessindustrie (1)
- Pseudo symmerty (1)
- Pt catalysts (1)
- Pt–Si layers (1)
- Pull-out test (1)
- Pulse echo technique (1)
- Pyrite (1)
- Quality control tool (1)
- Quality infrastructure (1)
- Qualitätskontrolle (1)
- Quantification (1)
- Quantitative concentration (1)
- Quantummechanical molecular dynamics simulation (1)
- REM-EDX (1)
- RFID based sensors (1)
- RT (1)
- Raman Mikroskopie (1)
- Raman imaging (1)
- Raman microscopy (1)
- Raman-Spektroskopie (1)
- Reaction Monitoring (1)
- Reactive azo dye degradation (1)
- Rebar (1)
- Reference Material (1)
- Referenzmaterialien (1)
- Reflection seismics (1)
- Reinheitsbestimmung (1)
- Reverse time migration (1)
- Rice husk as (1)
- Roadmap (1)
- Rotaxanes (1)
- Röntgenröhre (1)
- SEIRA methodology (1)
- SEM-EDX (1)
- SERS (1)
- SHM (1)
- SPME-GC-MS (1)
- SPPS (1)
- Saffron (1)
- Salsa (1)
- Sample loss (1)
- Scaled boundary finite element method (1)
- Scanning Electron Microscopy (SEM) (1)
- Schwerflüchtige organische Verbindungen (1)
- Security (1)
- Seismic (1)
- Seismics (1)
- Sensitized magnetic nanocatalysts (1)
- Sequencing (1)
- Silicone rubber (1)
- Silk Roas Sites (1)
- Single-cell fusion (1)
- Single-molecule magnets (1)
- Solid-phase peptide synthesis (1)
- Solvothermal syntheses (1)
- Sonden (1)
- Sonderprobenanalytik (1)
- Spike (1)
- Split and mix technology (1)
- Spurenelemente (1)
- Stabilizer (1)
- Standards (1)
- Starch (1)
- Steel slag (1)
- Stress (1)
- Structural health monitoring (1)
- Structure viewer (1)
- Subgroup relationships (1)
- Sulfamethoxazole (1)
- Sulfo-NHS (1)
- Sulfur (1)
- Superplasticizer (1)
- Supplementary cementitious materials (1)
- Surface analysis (1)
- Surface functional groups (1)
- Surfactant (1)
- Sustainability (1)
- Sustainable (1)
- Synchrotron (1)
- Synchrotron XRD (1)
- Synchrotron measurements (1)
- TKD (1)
- TPH (1)
- TSA (1)
- Tagungsband (1)
- Tensile test inside a TEM (1)
- Tentagel (1)
- Thermografie (1)
- Thermographie (1)
- Timber (1)
- Time-gated fluorescence detection (1)
- ToF-SIMS (1)
- Total cyanide (1)
- Trace elements (1)
- Transducer (1)
- Transducers (1)
- Transmission Electron Microscopy (TEM) (1)
- Transmissionstarget (1)
- Troubleshooting Samples Analytics (1)
- UV-vis Spectrometry (1)
- Ultrasonic test (1)
- Ultrasound concrete (1)
- Untersuchung von CFK (1)
- Uranine (1)
- Verbundfestigkeit (1)
- Verteilte Sensorik (1)
- Voltammetric electronic tongue (1)
- Volume fraction (1)
- Wall paint (1)
- Water structure (1)
- Wear particle analysis (1)
- Wärmeverluste (1)
- X-ray Fluorescence analysis (1)
- ZfP (1)
- Zugfestigkeit (1)
- absorption (1)
- add-on Funktionen (1)
- ageing (1)
- archaeology (1)
- artificial weathering (1)
- bio-diagnostic (1)
- cold neutrons (1)
- computed tomography (1)
- crystal structures (1)
- degradation (1)
- electrochemical dealloying (1)
- emission (1)
- estrogenic activity (1)
- extraction (1)
- iron embrittlement (1)
- leaching (1)
- maghemite (1)
- metal (1)
- nanoparticles (1)
- nanotechnology (1)
- neutron imaging (1)
- neutron instrumentation (1)
- nutritional supplements (1)
- oxidation state (1)
- pore structure (1)
- rubber (1)
- serine-protease inhibitor (1)
- sporting track (1)
- ssNMR spectroscopy (1)
- structural information (1)
- surface modification (1)
- upconverting nanoparticles (UCNPs) (1)
Eingeladener Vortrag
- nein (23)
Ziel dieser Arbeit war die Entwicklung einer Methode zur Hochdurchsatzanalyse von partikelgebundenen Split-and-Mix-Peptidbibliotheken. Dabei wurde ein System entwickelt, das Partikelbibliotheken in kurzer Zeit auf ihre Bindung zu einem Zielmolekül hin untersucht und im nächsten Schritt eine direkte „Ein-Partikel“-Sequenzierung der Peptide von der festen Phase ermöglicht. Die Analyse der Bindung eines Zielmoleküls an ein selektiv bindendes Peptid wurde dabei in einem Modellsystem simuliert. Dazu wurde FITC-markiertes Neutravidin 3 mit festphasengebundenen biotinylierten und nicht-biotinylierten Peptiden inkubiert. Die Bindung von Neutravidin-FITC an die biotinylierten Peptide konnte erfolgreich mittels eines Fluoreszenzmikroskops nachgewiesen werden, wobei diese Methode für eine Hochdurchsatzanalyse ungeeignet war. So wurde die Analyse des Fluoreszenzassays auf einen Microarrayscanner übertragen (siehe Abbildung 33). Dies gelang erfolgreich wobei die hohe Eigenfluoreszenz des Tentagel-Harzes zu falsch positiven Ergebnissen führte. Mit einem Wechsel zum längerwelligen Fluoreszenzfarbstoff ATTO-633 konnten falsch positive Ergebnisse vermieden werden. Somit wurde die zeitintensive Fluoreszenzanalyse von einem Fluoreszenzmikroskop erfolgreich auf einen Microarrayscanner übertragen, welcher in kurzer Zeit (ca. 5 min pro Objektträger) eine Vielzahl an peptidbeladenen Partikeln gleichzeitig analysieren kann.
Quo Vadis – Kurzdarstellung
Im Fokus von Quo Vadis stehen die Qualitätssicherung von Verbundwerkstoffen und die Validierung der Zentrifugentechnologie zur quantitativen Bestimmung von Festigkeitswerten in der Beanspruchung auf Zug als Mehr-Proben-Prüfverfahren unter Verwendung einer analytischen Zentrifuge (nachfolgend als „Adhesion Analyser LUMiFrac®“ bezeichnet). Zu den Festigkeiten, die mit Hilfe des LUMiFrac® unter Verwendung aufgeklebter Prüfstempel bestimmt werden, gehören die Fügefestigkeit (FF) von Klebverbindungen, die Haftfestigkeit (HF) von Beschichtungen sowie die Verbundfestigkeit (VF) von Faserverbundwerkstoffen. Aufbauend auf zwei Funktionsmustern der analytischen Zentrifuge sollen für die genannten Anwendungsszenarien (FF, HF, VF) in Anlehnung an die geltenden Normen DIN EN 15870 „Klebstoffe – Zugprüfung zur Bestimmung der Zugfestigkeit von Stumpfklebungen“ und DIN EN ISO 4624 „Beschichtungsstoffe – Abreißversuch zur Beurteilung der Haftfestigkeit“ geeignete Prüfstrategien und -abläufe sowie zum Klebprozess kompatible Aufnahmen für den Prüfkörperverbund in der Zentrifuge entwickelt werden.
Im Ergebnis des Vorhabens soll ein automatisiertes und validiertes Mehr-Proben-Prüfverfahren zur Qualitätssicherung von Verbundfestigkeiten zur Verfügung stehen, welches neben der Hardware auch eine Software für die angepassten Prüfstrategien in Form von SOPs (standard operating procedures) bereitstellt.
Im Fokus steht die Qualitätssicherung mit Blick auf Herstellung, Modifizierung, Handling und Erprobung von PLASMA-kompatiblen Partikeln zur gepulsten in-situ Injektion von ex-situ hergestellten Partikeln für add-on Funktionen in und zur Identifikationsprüfung von BeschichTungen (PLASMA-FIT). Im Kern war zunächst zu prüfen, welche Klassen ex-situ hergestellter Partikel unterschiedlichster Materialien überhaupt bzw. unter welchen Bedingungen PLASMA-fit sind oder unter welchen Randbedingungen PLASMA-fit gemacht werden können. In den dazugehörenden Projektphasen Screening und Adaption stand dabei das komplexe Beanspruchungsszenario bestehend aus Vakuum-, Temperatur- und wenigstens kurzzeitiger Plasmabeständigkeit der ex-situ bereitgestellten Partikel im Fokus. In der Projektphase Applikation sollte dann unter Verwendung einer modifizierten Plasmaquelle (BAM-Patentanmeldung, beabsichtigte Lizenznahme durch Fa. CemeCon, Optionsvertrag) hinsichtlich der Realisierbarkeit, Prüfung und Qualitätssicherung von Plasmadispersionsschichten ein erster Praxistest zur in-situ Injektion von Partikeln in einen laufenden Beschichtungsprozess, zur Realisierung funktioneller Eigenschaften z.B. zur Identifikation oder Authentifizierung von Originalteilen, vorgenommen werden
The qualitative and quantitative investigations of historical iron-gall inks by use of μ-XRF spectrometry is a common method for analyzing the diff erences in their composition. When a fingerprint is established, it is possible to characterize the distinguishable inks used in the production of medieval manuscripts, and, in turn assist in the reconstruction of the manuscript’s history.The characterization of the primary inks in palimpsests, i.e. manuscripts written on re-used parchment, presents a serious problem as the effect of the partial removal on the inks fi ngerprint is yet known.
In this paper we explore our preliminary results concerning the effects of two removal techniques on the fingerprint of iron-gall inks on parchment.
This project aims to develop capacity to produce certified reference materials (CRMs) for environmental analysis by transferring know-how between the partners and combining their skills to focus on environmental CRM production. The production process includes good manufacturing practices for processing materials, method development, the validation and application of homogeneity, stability and characterisation tests, the calculation of individual uncertainties (between-unit inhomogeneity, long term stability, characterisation) and combination of uncertainties to determine overall uncertainty of the matrix reference materials. An inter laboratory comparison registered as a EURAMET project is set as the ultimate project outcome, confirming the partners’ capabilities in applying newly acquired skills.
This project aims to develop capacity to produce certified reference materials (CRMs) for environmental analysis by transferring know-how between the partners and combining their skills to focus on environmental CRM production. The production process includes good manufacturing practices for processing materials, method development, the validation and application of homogeneity, stability and characterisation tests, the calculation of individual uncertainties (between-unit inhomogeneity, long term stability, characterisation) and combination of uncertainties to determine overall uncertainty of the matrix reference materials. An inter laboratory comparison registered as a EURAMET project is set as the ultimate project outcome, confirming the partners’ capabilities in applying newly acquired skills.
The importance of microRNA (miRNA) dysregulation for the development and progression of diseases and the discovery of stable miRNAs in peripheral blood have made these short-sequence nucleic acids next-generation biomarkers. Here we present a fully homogeneous multiplexed miRNA FRET assay that combines careful biophotonic design with various RNA hybridization and ligation steps. The single-step, single-temperature, and amplification-free assay provides a unique combination of performance parameters compared to state-of-the-art miRNA detection technologies. Precise multiplexed quantification of miRNA-20a, -20b, and -21 at concentrations between 0.05 and 0.5 nm in a single 150 mL sample and detection limits between 0.2 and 0.9 nm in 7.5 mL serum samples demonstrate the feasibility of both highthroughput and point-of-care clinical diagnostics.
One of the most important collections of manuscripts and wall paintings from sites of the northern Silk Road, discovered at the beginning of the 20thC, are deposited in Berlin. The fragments represent a broad spectrum of scripts, languages, and painting styles depending on the region of origin and purpose of dissemination. The manufacturing material reflects the various influences in the oasis sites. Based on analyses of some pigments, examples are posed.
Sixteen Ayyubid-Mamluk glazed pottery sherds were analyzed in order to identify and characterize the elemental composition to determine their provenance. The tested sherds were collected from the historical site of Karak Castle, southern Jordan.
Chemical analysis for the sixteen samples has been carried out using Synchrotron Radiation X-ray Fluorescence Spectrometry (SR-XRF) Technique. Furthermore, the semiquantitative analysis of the elements Fe – Cu – Zn – Br – Rb – Sr – Y – Zr – Nb – Mo – Pd – Ag – Cd and Pb has been performed for the samples based on Principal Component Analysis (PCA) and hierarchical Cluster Analysis with Bray-Curtis in order to define grouping of different glazed pottery by obtaining information on their similarity and clustering. The results of chemical analysis provided persuasive evidence that the Karak Castle pottery sherds have at least three different sources of provenance.
The modeling of waveguides by means of the Scaled Boundary Finite Element Method (SBFEM) has recently been addressed and is considered an effective procedure for the simulation of ultrasonic guided waves in plates and uniform structures, as well as their interaction with defects. This work presents the extension of the known applications like uniform concrete foundation cylinders to structures with more complex shapes and defects. The main focus is the required modeling of 3-D structures in SBFEM to solve these efficiently. Furthermore the coupling of different models is discussed. This involves models like a mainly uniform foundation cylinder with varying material behavior or geometry in certain areas which has to be modeled in 3-D SBFEM. With the presentation of numerical examples the accuracy and performance of the modeling is discussed and the advantages in improving numerical stability are shown.