Analytische Chemie
Filtern
Erscheinungsjahr
- 2016 (1)
Dokumenttyp
- Vortrag (1)
Sprache
- Englisch (1)
Referierte Publikation
- nein (1)
Schlagworte
- Surface analysis; (1) (entfernen)
Eingeladener Vortrag
- nein (1)
The surface modification of nanometer- and micrometer-sized particles with polyethylene glycol (PEG) ligands of varying length is a very common strategy to tune their hydrophilicity and biocompatibility, minimize unspecific interactions, improve biofunctionalization efficiencies, and enhance blood circulation times. Nevertheless, simple methods for the quantification of PEG ligands are rare. This is similarly true for the spectroscopic characterization of lanthanide-doped upconverting nanoparticles (UCNPs), novel near infrared (NIR)-excitable nonlinear fluorescence reporters for bioanalysis and theranostics, providing background-free multiple narrow emission bands in the visible and NIR, excellent photostability, and long luminescence lifetimes.
We present here a simple method for the determination of the number of PEG ligands on nanomaterials and screening methods for the fast identification of nonradiative deaction pathways in UCNPs.