Nano
Filtern
Dokumenttyp
- Zeitschriftenartikel (347)
- Vortrag (338)
- Posterpräsentation (100)
- Forschungsdatensatz (50)
- Sonstiges (20)
- Beitrag zu einem Tagungsband (16)
- Buchkapitel (10)
- Beitrag zu einem Sammelband (10)
- Forschungsbericht (9)
- Zeitschriftenheft (Herausgeberschaft für das komplette Heft) (6)
Sprache
- Englisch (870)
- Deutsch (52)
- Spanisch (2)
- Mehrsprachig (1)
Schlagworte
- Nanoparticles (124)
- Nano (70)
- SAXS (64)
- XPS (60)
- Laser-induced periodic surface structures (LIPSS) (59)
- Fluorescence (53)
- Quantum yield (51)
- Electron microscopy (48)
- Nanoparticle (46)
- X-ray scattering (46)
- SEM (40)
- Nanomaterial (39)
- Quality assurance (39)
- Lifetime (35)
- VAMAS (35)
- HAXPES (33)
- Dye (32)
- Particle size distribution (30)
- Particle (29)
- Sensor (28)
- Nanomaterials (27)
- Lanthanide (26)
- Photophysics (25)
- MOUSE (24)
- Surface functionalization (24)
- Standardisation (23)
- Graphene (22)
- Photoluminescence (22)
- Synthesis (22)
- Method (21)
- Reference material (21)
- Simulation (20)
- Small-angle X-ray scattering (20)
- X-ray photoelectron spectroscopy (20)
- AFM (19)
- Interlaboratory comparison (19)
- NIR (19)
- Boehmite (17)
- Nanocomposites (17)
- Quantum dots (17)
- Reference materials (17)
- Sample preparation (17)
- Thin films (17)
- Traceability (17)
- Geant4 (16)
- Imaging (16)
- Laser processing (16)
- NanoSolveIT (16)
- Nanocomposite (16)
- Upconversion nanoparticle (16)
- Inter-laboratory comparison (15)
- Surface chemistry (15)
- Functionalized graphene (14)
- Metrology (14)
- Microdosimetry (14)
- Upconversion (14)
- Applications (13)
- Dosimetry (13)
- Femtosecond laser (13)
- Geant4-DNA (13)
- Luminescence (13)
- MCS (13)
- OECD (13)
- Quantum dot (13)
- SWIR (13)
- Scattering (13)
- DNA (12)
- EDS (12)
- Ellipsometry (12)
- Optical spectroscopy (12)
- Polymer (12)
- Quantitative spectroscopy (12)
- Conductivity (11)
- EBSD (11)
- Nanostructures (11)
- Particle size (11)
- Size (11)
- Surface analysis (11)
- Brightness (10)
- Energy transfer (10)
- Femtosecond laser ablation (10)
- Integrating sphere spectroscopy (10)
- LEE (10)
- Mechanism (10)
- Radiation damage (10)
- Small angle scattering (10)
- Standardization (10)
- TiO2 (10)
- Atomic force microscopy (9)
- AuNP (9)
- Broadband dielectric spectroscopy (9)
- Epoxy (9)
- Friction (9)
- Gold (9)
- Methodology (9)
- Microstructures (9)
- Monte-Carlo simulation (9)
- Oxygen evolution reaction (9)
- Quantification (9)
- Radioactive decay (9)
- Silica (9)
- Surface (9)
- Wear (9)
- Energy deposit (8)
- Nanoconfinement (8)
- Protein (8)
- Rigid amorphous fraction (8)
- Spectroscopic ellipsometry (8)
- Additive manufacturing (7)
- Advanced materials (7)
- Automation (7)
- Cancer treatment (7)
- Coating (7)
- DNA damage (7)
- Excitation power density (7)
- FIB (7)
- Flash DSC (7)
- Ionic Liquid crystals (7)
- Ligand (7)
- Monte-Carlo simulations (7)
- Nanoplastics (7)
- Nanostructure (7)
- Radiationtherapy (7)
- Reference data (7)
- Shape (7)
- Single particle (7)
- Spectroscopy (7)
- TEM (7)
- TOPAS (7)
- Titania nanoparticles (7)
- ToF-SIMS (7)
- Uncertainty (7)
- Advanced Materials (6)
- Assay (6)
- Beta decay (6)
- Brachytherapy (6)
- Calibration (6)
- Cell (6)
- Flow cytometry (6)
- G5P (6)
- Glass (6)
- Gold Nanoparticles (6)
- Indium phosphide (6)
- Lab automation (6)
- Laser ablation (6)
- Laser-induced periodic surface structures, LIPSS (6)
- Low energy electrons (6)
- Measurement uncertainty (6)
- Multiplexing (6)
- NP (6)
- Nano powder (6)
- Nanoplastic (6)
- Particle scattering simulations (6)
- Prüfrichtlinie (6)
- Radiation therapy (6)
- Radiolysis (6)
- Reproducibility (6)
- Small-angle scattering (6)
- TOPAS-nbio (6)
- Temperature (6)
- VSSA (6)
- Adsorbed Layer (5)
- Analysis (5)
- Application (5)
- Bacteria (5)
- Biofilm (5)
- Cancer (5)
- Carbon nanotubes (5)
- Characterization (5)
- Core-shell (5)
- Data analysis (5)
- Dynamics (5)
- EPMA (5)
- Ectoine (5)
- Elastomers (5)
- Elemental composition (5)
- Environment (5)
- ISO/TC 202 (5)
- LLG (5)
- Mesoporous iridium oxide films (5)
- Micromagnetism (5)
- Microscopy (5)
- Multiphoton lithography (5)
- Nanocrystal (5)
- Nanoparticle concentration (5)
- Nanosafety (5)
- Nanotechnology (5)
- OH radical (5)
- OOMMF (5)
- Oxidation (5)
- Particle scattering (5)
- Polycarbonate (5)
- Risk assessment (5)
- Rubber (5)
- Semiconductor quantum dot (5)
- Sensing (5)
- SiO2 (5)
- Single-stranded DNA-binding proteins (5)
- Software (5)
- Surfaces (5)
- Topas (5)
- X-ray (5)
- XRD (5)
- nPSize (5)
- 2D materials (4)
- 3D (4)
- Advanced manufacturing (4)
- BDS (4)
- Bacterial adhesion (4)
- Barcoding (4)
- Bead (4)
- Bending modulus (4)
- Bio-SAXS (4)
- Bioimaging (4)
- Calcium sulfate (4)
- Capillary waves (4)
- Catalysis (4)
- Certification (4)
- Clustered nanoparticles (4)
- Corrosion (4)
- Cosolute (4)
- Crystallization (4)
- DLS (4)
- Data (4)
- Data stewardship (4)
- Diffraction (4)
- Direct laser writing (4)
- EC4SafeNano (4)
- Ectoin (4)
- Encoding (4)
- Epoxy nanocomposites (4)
- Exchange interaction (4)
- Fast Scanning Calorimetry (4)
- Ferromagnetism (4)
- GVP (4)
- Glass transition (4)
- Guideline (4)
- Hard X-ray photoelectron spectroscopy (HAXPES) (4)
- ISO/TC 229 (4)
- Image analysis (4)
- Image segmentation (4)
- InP (4)
- Instrumentation (4)
- Introduction (4)
- Ionic liquid (4)
- Ionizing radiation damage (4)
- Iron oxide (4)
- Iron oxide nanoparticles (4)
- Knowledge Readiness Level (4)
- Landau Lifshitz equation (4)
- Life sciences (4)
- Livermore model (4)
- Magnetic moment (4)
- McSAS3 (4)
- Microbeam Analysis (4)
- Microbeam analysis (4)
- Microstructure (4)
- Modelling (4)
- NEXAFS (4)
- Nano@BAM (4)
- NanoDefine (4)
- Nanoelectronics (4)
- Nanofibers (4)
- Nanomaterial classification (4)
- Nanopartikel (4)
- Non-destructive operando analysis (4)
- Nucleation (4)
- OH radical scavenger (4)
- Object oriented micromagnetic framework (4)
- Optical assay (4)
- Orientation (4)
- PDF (4)
- Penelope model (4)
- Polymers (4)
- Probe (4)
- Protein unfolding (4)
- Radiotherapy (4)
- Reference product (4)
- Regulation (4)
- Round robin (4)
- Signal enhancement (4)
- Size distribution (4)
- Standard (4)
- Stochastic Landau Lifshitz Gilbert equation (4)
- Strategic Research Agenda (SRA) (4)
- Surface modification (4)
- Synchrotron (4)
- TMDSC (4)
- Thickness (4)
- Titanium dioxide (4)
- Transmission electron microscopy (4)
- Two-photon polymerization (4)
- Ultrashort laser processing (4)
- particle scattering (4)
- ssDNA (4)
- AIS (3)
- Aggregation (3)
- Aging (3)
- Analytical sciences (3)
- Antibacterial (3)
- Atomic Force Microscopy (3)
- Automated synthesis (3)
- BAM reference data (3)
- BioSAXS (3)
- Biofilm formation (3)
- CLS (3)
- Cement (3)
- Ceria (3)
- Contact resonance (3)
- Core-shell nanoparticles (3)
- Correlative analysis (3)
- Correlative imaging (3)
- Cycloalyphatic epoxy oligosiloxane (3)
- Cytotoxicity (3)
- Differential scanning calorimetry (3)
- Electrochemistry (3)
- Electromagnetic scattering (3)
- Electron Microscopy (3)
- Electrospinning (3)
- Energy dispersive X-ray spectroscopy (3)
- European Centre (3)
- European Metrology Network (EMN) (3)
- Extracellular vesicles (EV) (3)
- FTIR (3)
- Femtosecond laser processing (3)
- Framework (3)
- Free electron laser (3)
- General Materials Science (3)
- Gold nanocluster (3)
- Graphene oxide (3)
- Graphene related 2D materials (3)
- Growth Kinetics (3)
- Hard-energy X-ray photoelectron spectroscopy (3)
- Hybrid metrology (3)
- ISO (3)
- ISO/TC 229 Nanotechnologies (3)
- Immunoassay (3)
- Intermodulation AFM (3)
- Interpenetrating polymer network (3)
- Interphase (3)
- LIPSS (3)
- Laboratory automation (3)
- Laboratory management (3)
- Limit of detection (3)
- Linearity (3)
- Lubricants (3)
- MOF (3)
- Machine Learning (3)
- Machine learning (3)
- Magnetic nanoparticles (3)
- Mechanical properties (3)
- Method comparison (3)
- Method development (3)
- Micro- and nanoplastics (3)
- Microprinting (3)
- Modeling (3)
- Monte Carlo (3)
- NAP-XPS (3)
- NMR (3)
- Nano particle (3)
- Nano-powder (3)
- Nanomaterialien (3)
- Nanopipettes (3)
- Nanostructure quantification (3)
- OH Radical (3)
- OH radicals (3)
- Optical assays (3)
- Particle Synthesis (3)
- Photocatalysis (3)
- Pollutant (3)
- Polyglycerol (3)
- Porosity (3)
- Porous materials (3)
- Processing (3)
- Protein G (3)
- Proteins (3)
- Python (3)
- Quantitative NMR (3)
- ROS (3)
- Radical Scavenger (3)
- Ratiometric sensors (3)
- Resonance frequency (3)
- Rigidity (3)
- SAXS/WAXS (3)
- SEM/EDS (3)
- SOP (3)
- Safe-by-Design (3)
- Scattering pattern analysis (3)
- Semiconductor (3)
- Sensors (3)
- Shell (3)
- Small-angle xray scattering (3)
- Stability (3)
- Standards (3)
- Surface chemical analysis (3)
- Surface group analysis (3)
- Surface group quantification (3)
- Test guideline (3)
- Thin Films (3)
- Ti6Al4V alloy (3)
- Time-resolved scattering (3)
- Topas-MC (3)
- Topas-nBio (3)
- Toxicology (3)
- Transmission Kikuchi Diffraction (TKD) (3)
- Tribology (3)
- Ultrafast laser processing (3)
- Ultrashort laser pulses (3)
- Upconversion nanocrystal (3)
- Upconversion nanoparticles (3)
- Validation (3)
- X-ray Photoelectron Spectroscopy (3)
- beta particle (3)
- nanoparticle (3)
- pH probe (3)
- pH sensing (3)
- 100Cr6 (2)
- 150th anniversary (2)
- 2D Materials (2)
- 2PP (2)
- 3D Fourier Transform (2)
- 3D printing (2)
- ABC (2)
- ACEnano (2)
- APTES (2)
- Absolute fluorescence (2)
- Achsschenkel (2)
- Adsorption (2)
- Advanced Manufacturing (2)
- Advanced nanomaterials (2)
- Affinity chromatography (2)
- Agglomerates (2)
- Aktivkohle (2)
- Amorphous silica particles (2)
- Amplification (2)
- Amyloid (2)
- Anodization (2)
- Antibody (2)
- Antibody coating (2)
- Au (2)
- Automated image analysis (2)
- Automatisation (2)
- BAM (2)
- BET (2)
- Bacterial adhesion tests (2)
- Base damage (2)
- Base loss (2)
- Behavior and Systematics (2)
- Beta particle (2)
- Bio-based concrete (2)
- Bioconjugation (2)
- Biofilm growth (2)
- Biosensor (2)
- Bruchmechanische Auslegung (2)
- Bundesanstalt für Materialforschung und -prüfung (2)
- Bundesoberbehörden (2)
- CEN/TC 352 Nanotechnologies (2)
- Case studies (2)
- Catalysts (2)
- Cathodoluminescence (2)
- CeO2 (2)
- Cell studies (2)
- Ceramics and Composites (2)
- Characterisation (2)
- Chemical admixtures (2)
- Chemical analysis (2)
- Chemical composition (2)
- Cleavable probe (2)
- Cluster (2)
- Coatings (2)
- Collection (2)
- Commercial graphene (2)
- Comparison (2)
- Complex (2)
- Composites (2)
- Concentration (2)
- Concrete (2)
- Conductometry (2)
- Convolutional neural networks (2)
- Correlative Imaging (2)
- Cr(III) (2)
- Cribellate spiders (2)
- Crosslinker (2)
- DNA radiation damage (2)
- Data conversion (2)
- Data curation (2)
- Data fitting (2)
- Data organization (2)
- Decision support (2)
- Desintegracion radioactiva (2)
- Diagnosis (2)
- Dielectric Spectroscopy (2)
- Dielectric spectroscopy (2)
- Diopside (2)
- Direct damage (2)
- Direct laser interference patterning (DLIP) (2)
- Direct laser-interference patterning (DLIP) (2)
- Discotic Liquid Crystals (2)
- Dispersion process (2)
- Dissociative electron attachment (DEA) (2)
- Dissociative electron transfer (DET) (2)
- Double-strand break (DSB) (2)
- Dynamic Light Scattering (2)
- EDX (2)
- EMN (2)
- EMPIR (2)
- EMPIR 18HLT01 MetVesII (2)
- ESCA (2)
- EU FP7 project NanoValid (2)
- Ecology (2)
- Ectrocatalysis (2)
- Electrocatalysis (2)
- Electrolysis (2)
- Elektronenmikroskopie (2)
- Engineered Nanomaterials (2)
- Enhancement strategy (2)
- European Metrology Networks (EMNs) (2)
- Evolution (2)
- Excitation (2)
- FAIR (2)
- FFT (2)
- FLIM (2)
- Fail-safe (2)
- Fast scanning calorimetry (2)
- Fe3O4 (2)
- FeNi (2)
- FeNi-Oxide NPs (2)
- Film thickness (2)
- Finite-difference time-domain calculations (2)
- Flame retardancy (2)
- Flow cytometry (FCM) (2)
- Fluorescence standard (2)
- Fluorescent particles (2)
- Fluoride (2)
- Force distance curve (2)
- Fourier Transform (2)
- Fourier transforms (2)
- Functionalization (2)
- Funtional Groups (2)
- Gallium doping (2)
- Gene five protein (2)
- Glue (2)
- Graphene inks (2)
- Graphene oxide flakes (2)
- Graphene powder (2)
- Graphitization (2)
- HDF5 (2)
- Halloysite nanotubes (2)
- Hard x-ray photoelectron spectroscopy (2)
- Herceptin (2)
- Hierarchical micro-nanostructures (2)
- High resolution (2)
- Holistic experimental procedures (2)
- Holistic experimentation (2)
- Holistic science (2)
- Homogeneity (2)
- Hydrated DNA (2)
- Hydrated electron (2)
- Hydration (2)
- Hydration shell (2)
- Hydrogen evolution reaction (2)
- Hydroxyectoine (2)
- Hydroxyl radical (2)
- ICP-MS (2)
- IgG (2)
- Immunoassays (2)
- Immunocapture (2)
- Immunoglobulins (2)
- Immunoprecipitation (2)
- Immunosensor (2)
- In-situ (2)
- Indirect damage (2)
- Industrial applications (2)
- Instrument calibration (2)
- Interfaces (2)
- Interlaboratory Comparison (2)
- Interlaboratory Comparisons (2)
- Ionic Liquid Crystals (2)
- Ionisation (2)
- Ionization (2)
- Jahrestag (2)
- Kerbschlagarbeit (2)
- Kikuchi (2)
- Korrelation (2)
- Korrosion (2)
- Latex (2)
- Lattice parameters (2)
- Layer-by-layer deposition (2)
- Ligands (2)
- Lubrication (2)
- Material sciences (2)
- Measurement data conversion (2)
- Mesoporous (2)
- Metal cluster (2)
- Metal organic framework (2)
- Metals and Alloys (2)
- Method validation (2)
- Microanalysis (2)
- Microfluidics (2)
- Micropatterning (2)
- Microplastic (2)
- Microplastics (2)
- Molecularly Imprinted Polymers (2)
- Monitoring (2)
- Morphology (2)
- Multi photon lithography (2)
- Multilayer graphene (2)
- Multiphoton Lithography (2)
- Método de Montecarlo (2)
- NXsas (2)
- Nano- and microsensors (2)
- Nano-safety (2)
- Nanocarrier (2)
- Nanocharacterisation (2)
- Nanofasern (2)
- Nanoindentation (2)
- Nanomechanics (2)
- Nanometrology (2)
- Nanopulver (2)
- Nanorisk (2)
- Nanosensor (2)
- Nanostructure investigation (2)
- Natural rubber (2)
- NeXus (2)
- Near ambient pressure xray photo electron spectroscopy (2)
- Net-ionization reaction (2)
- Neural networks (2)
- Neutron (2)
- Neutron scattering (2)
- Niobium (2)
- Non-spherical shape (2)
- OECD TG 124 (2)
- OER (2)
- Oberflächenfunktionalisierung (2)
- Optical Spectroscopy (2)
- Optical probe (2)
- Oriented immobilization (2)
- Osmolyte (2)
- Oxygen (2)
- PAG (2)
- PDT (2)
- PEG (2)
- Particle number concentration (2)
- Particle scattering simulation (2)
- Particle size and shape distribution (2)
- Particle size distributuion (2)
- Particle surface analysis (2)
- Particle synthesis (2)
- Partikel (2)
- Partikelgrößenverteilung (2)
- Peptide (2)
- Peptide Library (2)
- Performance validation (2)
- Permethrin (2)
- Perovskite (2)
- Ph (2)
- Phosphor (2)
- Photocuring (2)
- Photonic crystal (2)
- Photoresist (2)
- Plant Science (2)
- Polydopamine (2)
- Polymer blends (2)
- Polymer nanocomposites (2)
- Polymer particle (2)
- Polymer-based nanocomposites (2)
- Polymers of Intrinsic Microporosity (2)
- Polypropylene (2)
- Polysaccharides (2)
- Power density (2)
- Prehydrated electron (2)
- Presolvated electron (2)
- Protein A (2)
- Proximity-enhanced reaction (2)
- Pump-probe experiments (2)
- Quantitative Analysis (2)
- Quantum yields (2)
- Quasi-direct damage (2)
- Radical (2)
- Radical scavenger (2)
- Radioactive nanoparticle (2)
- Raman (2)
- Ratio refinement (2)
- Reactive oxygen species (2)
- Reference Material (2)
- Reliability (2)
- Reproducibility crisis (2)
- Rheology (2)
- Robotics (2)
- Rosin (2)
- SANS (2)
- SBA-15 (2)
- SIMS (2)
- SZ2080 negative photo-resist (2)
- Safety (2)
- Saxs (2)
- Scanning electron microscopy (2)
- Scicat (2)
- Secondary ion mass spectrometry (2)
- Self-assembly (2)
- Self-organization (2)
- Sensor molecules (2)
- SiGe (2)
- Silane (2)
- Silanization (2)
- Silica and Polystyrene Particles (2)
- Silica and polystyrene nanoparticles (2)
- Silica nanoparticles (2)
- Silicon (2)
- Silver nanoparticle (2)
- Single particle spectroscopy (2)
- Single-strand break (SSB) (2)
- Special issue (2)
- Spectroscopic Ellipsometry (2)
- Spectroscopic imaging ellipsometry (2)
- Stakeholder (2)
- Standardisierung (2)
- Starch (2)
- Starch nanoparticle (2)
- Steel (2)
- Structure-property relationship (2)
- Struvite (2)
- Surface Analysis (2)
- Surface Group Analysis (2)
- Surface charge (2)
- Surface morphology (2)
- Surface oxidation (2)
- Sustainability (2)
- Synchrotron radiation (2)
- Sythesis (2)
- TED-GC/MS (2)
- TGA (2)
- TKD (2)
- Temeprature scaling (2)
- Temperature scaling (2)
- Test material (2)
- Thermoanalytik (2)
- Thermoplastics (2)
- Thin polymer films (2)
- TiAl64V (2)
- Time-of-flight secondary ion mass spectrometry (ToF-SIMS) (2)
- Titania (2)
- Titanium alloy (2)
- Titration (2)
- Transmission electron microscopy (TEM) (2)
- Transparency (2)
- Transparent Conductive Oxides (2)
- Two photon polymerisation (2)
- Ultra thin polymer films (2)
- Uncertainties (2)
- Virus inhibition (2)
- Volume specific surface area (2)
- WAXS (2)
- White light interference microscopy (2)
- X-ray diffraction (2)
- X-ray spectroscopy (2)
- XANES (2)
- Xray (2)
- Xray photo electron spectrocopy (2)
- Zeta potential (2)
- Zinc oxide (2)
- fluorescence (2)
- low energy electrons (2)
- nanoparticula (2)
- pH (2)
- (Hard) X-ray Photoelectron Spectroscopy (1)
- 100Cr6 (AISI 52100) steel (1)
- 18HLT01 MetVes II (1)
- 2D (1)
- 2D flakes (1)
- 2D nanomaterial (1)
- 2D nanoparticle (1)
- 3D FFT (1)
- 3D etching (1)
- 3D printed hydrogel (1)
- 3D-printing (1)
- 3d structuring (1)
- 60-230V (1)
- AAAA (1)
- ACCORDs (1)
- ADA-GEL (1)
- AEROSIL® OX50 (1)
- AFM based test methods (1)
- AFM force spectroscopy (1)
- AFM-IR (1)
- AFM-Kraft-Abstand-Kurven (1)
- AI tool (1)
- AIS QD (1)
- ASAXS (1)
- ATH (1)
- ATZ (1)
- Aantimicrobial (1)
- Ab initio calculations (1)
- Absolute measurement (1)
- Absorption (1)
- Active Matter (1)
- Actuating materials (1)
- Additiv (1)
- Additive (1)
- Adhesion (1)
- Adhesives (1)
- Advanced optics (1)
- Ag (1)
- Ag2S (1)
- AgInS (1)
- Aggregation induced emission (1)
- Al-Composite (1)
- Al-based alloy (1)
- Al2O3 thin films (1)
- AlOOH (1)
- Albumin (1)
- Alloy 36 (1)
- Alpha (1)
- Alumina toughened zirconia (1)
- Aluminium alloy (1)
- Aluminium oxide hydroxide (1)
- Aluminiumoxid (1)
- Amphiphilicity (1)
- Analyses (1)
- Analysis approach (1)
- Analytical chemistry (1)
- Analytical methods (1)
- Analytical scanning electron microscopy (1)
- Analytical services (1)
- Analytische Zentrifuge (1)
- Anatase (1)
- Aneurism (1)
- Anhydrite (1)
- Anisotropy (1)
- Antiadhesive surfaces (1)
- Antibacterial properties (1)
- Antibacterial surfaces (1)
- Antibakterielle Oberflächen (1)
- Antibiotic delivery (1)
- Antibiotic release (1)
- Antibodies (1)
- Antibody-gated indicator delivery (1)
- Antifouling (1)
- Antikörper (1)
- Antimicrobial resistance (1)
- Antimicrobial titanium coating (1)
- Antioxydant (1)
- Antiviral activity (1)
- Aqueous quantum dot (1)
- Aqueous synthesis (1)
- Arbitrary shapes (1)
- Argon gas cluster ion sputtering (1)
- Aromatische Aminosäureanalytik (1)
- Article concentration (1)
- Artificial Intelligence (1)
- Artificial digestion (1)
- Artificial intelligence (1)
- Atomic force microscope (1)
- Atomic fraction (1)
- Au Nanoparticles (1)
- Au nanodisks (1)
- Au nanoparticles (1)
- Au-nanocubes (1)
- Augenbohne (1)
- Auger Electron Spectroscopy (1)
- Auger electron spectroscopy (1)
- Automated Image Analysis (1)
- Automated analysis (1)
- Automated assay (1)
- Autonomous Materials Discovery (1)
- Aza-BODIPY (1)
- BADGER film (1)
- BAM Academy (1)
- BCA (1)
- BMU (1)
- BNP (1)
- BODIPY (1)
- BODIPY probe (1)
- BSA (1)
- BTS (1)
- Bacteria repellent surfaces (1)
- Bacteria-repellent surfaces (1)
- BadgerFilm (1)
- Basidiomycetes (1)
- Bassanite (1)
- Bead-based assays (1)
- Benchmarking (1)
- Bessel-Strahlen (1)
- Bimetallic noble metal nanoparticles (1)
- Bimodal (1)
- Bimodal size distribution (1)
- Bio-ceramic engineering (1)
- Bio-orthogonal chemistry (1)
- Biochip (1)
- Biofilme (1)
- Biofilms (1)
- Biofunctional Molecules (1)
- Bioinspiration (1)
- Biomaterials (1)
- Biomimetic (1)
- Biomimetic surfaces (1)
- Bionic materials (1)
- Bioresorbable Biomaterials (1)
- Biosensing (1)
- Biosensors (1)
- Bipyramid (1)
- Black phosphorus (1)
- Bloch wall (1)
- Boehmite alumina (1)
- Boehmite nanoparticles (1)
- Bone screws (1)
- Bone tissue engineering (1)
- Boronic acid (1)
- Boronic acid-functionalized 2D MoS2 (1)
- Bradford-Assay (1)
- Bragg peak (1)
- Broadband dielectric microscopy (1)
- Brown-rot fungi (1)
- Brownian motion (1)
- Brownsche Molekularbewegung (1)
- Building and Construction (1)
- Bulk metallic glasses (1)
- Bulk temperature (1)
- Bystander effect (1)
- Böhmit (1)
- C++ (1)
- C-F bond activation (1)
- C7H15N2O4P (1)
- CCQM (Consultative Committee for Amount of Substance) (1)
- CE-ICP-MS (1)
- CEN (1)
- CO2 (1)
- CRP (1)
- CUINS2 nanocrystals (1)
- Calamistrum (1)
- Calcium sulfoaluminate (CSA) cement (1)
- Calibrated fluorescence measurements (1)
- Calibration structure (1)
- Cancer therapy (1)
- Carbon (1)
- Carbon Nanomembranes (1)
- Carbon black (1)
- Carbon dot (1)
- Carbon fibers (1)
- Carbon footprint (1)
- Carbon ions (1)
- Carbon nanoparticles (1)
- Carbon storage (1)
- Carrier protein (1)
- Catalogue of Services (CoS) (1)
- Catalogue of services (1)
- Catalyst (1)
- Catalyst layer (1)
- Catch and release assay (1)
- Cationic photocuring (1)
- Causes leading to scientific misconduct (1)
- CdS (1)
- CdTe quantum dots (1)
- Ce0.1Zr0.9O2 nanoparticles (1)
- Ce0.25Zr0.75O2 nanoparticles (1)
- Ce0.5Zr0.5O2 nanoparticles (1)
- Ce0.75Zr0.25O2 nanoparticles (1)
- Ce0.9Zr0.1O2 (1)
- CeO2 nanoparticles (1)
- CeO2/Co3O4 (1)
- Cell appendages (1)
- Cell size (1)
- Cell-repellent surfaces (1)
- Cells (1)
- Cellulose acetate (1)
- Cellulose nanofibrils (1)
- Ceramic matrix composites (1)
- Ceramic microprinting (1)
- Ceramic nano particles (1)
- Ceramics (1)
- Ceramics 3D printing (1)
- Cerium oxide (1)
- Certified Referencematerial (1)
- Certified reference materials (1)
- Certified reference nanomaterials (1)
- Ceruloplasmin (1)
- Cetrifugal Liquid Sedimentation CLS (1)
- Channel access (1)
- Characterization method (1)
- Charge (1)
- Charge transfer (1)
- Chemical analyses (1)
- Chemiluminescence (1)
- Chemistry (1)
- Chemometric analysis (1)
- Chromium (III) complexes (1)
- Civil and Structural Engineering (1)
- Classification (1)
- Cleavable linker (1)
- Cleavable probes (1)
- Click chemistry (1)
- Climate (1)
- Cmake (1)
- Co (1)
- Co0.75Fe2.25O4 nanoparticles (1)
- Co1.5Fe1.5O4 nanoparticles (1)
- Co2.25Fe0.75O4 nanoparticles (1)
- Co3O4 nanoparticles (1)
- Coaggregation (1)
- Coatings and Films (1)
- Cobalt (1)
- Coherent exchange (1)
- Colloidal semiconductor nanocrystals (1)
- Color (1)
- Color tuning (1)
- Combinatorial peptide library (1)
- Command line (1)
- Command-line interface (1)
- Commercialization (1)
- Comparability (1)
- Comparability of Measurement Results (1)
- Compatible solute (1)
- Complementary methodology and metrology (1)
- Complementary methods (1)
- Complex-shape (1)
- Composition (1)
- Compound semiconductors (1)
- Computed tomography (1)
- Computertomographie (1)
- Conference (1)
- Confined catalyst (1)
- Confocal raman imaging (1)
- Conjugate (1)
- Contrast agent (1)
- Controlled morphology (1)
- Controlled periodic illumination (1)
- Converter marterial (1)
- Converter material (1)
- Copper (1)
- Coprecipitation (1)
- Core-shell nanoparticle (1)
- Core-shell nanoparticle (CSNP) (1)
- Core-shell particles (1)
- Core-shell structures (1)
- Core/shell materials (1)
- Core/shell nanoparticle (1)
- Core/shell quantum dot (1)
- Core–shell particles (1)
- Correlative Spectroscopy (1)
- Corrosion rate (1)
- Coulomb explosion (1)
- Covalend functionalization (1)
- Covalent Organic frameworks (1)
- Covalent functionalization (1)
- Covalent interactions (1)
- Cr(III) complex (1)
- Critical strain (1)
- Cross-sectioning (1)
- Crosslinking (1)
- Crosslinking density (1)
- CuNPs (1)
- Cubical Iron Oxide (1)
- Cubical shape (1)
- Curie temperature (1)
- Curing (1)
- Curve fitting (1)
- Cycloaliphatic epoxy oligosiloxane (1)
- Cyclometalated iridium (III) complexes (1)
- DFT (1)
- DFT calculations of Raman spectra (1)
- DMAS (1)
- DMSO (1)
- DNA structures (1)
- DNA-Binding protein (1)
- DPA (1)
- DRIFTS (1)
- DSB (1)
- DSC (1)
- DTAB (1)
- Damage (1)
- Damping factor (1)
- Data Fusion (1)
- Data Management (1)
- Data analysis round robin (1)
- Data catalog (1)
- Data corrections (1)
- Data correlation (1)
- Data management (1)
- Data manipulation (1)
- Data pipelines (1)
- Data processing (1)
- Data provenance (1)
- Data readiness level (1)
- Data stewartship (1)
- Data visualisation (1)
- Databases (1)
- Datasets (1)
- Datenfusion (1)
- Debian (1)
- Debye scattering equation (1)
- Debye-Waller-Faktor (1)
- Decay kinetics (1)
- Defect Analysis (1)
- Defect photoluminescence (1)
- Definition (1)
- Definition of nanomaterial (1)
- Degradation signatures (1)
- Degradation studies (1)
- Demonstration (1)
- Dendritic polyglycerol (1)
- Density (1)
- Depth profiling (1)
- Deuterium (1)
- Diagnostic antibodies (1)
- Diclofenac (1)
- Diffractive gratings (1)
- Digestion (1)
- Digital laboratory (1)
- Digitalisation (1)
- Digitalisierung (1)
- Digitalization (1)
- Dimensional mismatch of crystalline lattice periods (misfit) (1)
- Diopsid (1)
- Direct Laser Writing (1)
- Direct laser interference patterning (1)
- Dispersion (1)
- Dispersion of nano materials (1)
- Dissolution (1)
- Distribution of nanoparticles (1)
- Domain wall (1)
- Doping (1)
- Drug delivery (1)
- Dual sensing (1)
- Durability (1)
- Dyad molecules (1)
- Dye labeling (1)
- Dyes (1)
- Dynamic behavior (1)
- Dynamic heterogeneity (1)
- Dynamische Lichtstreuung (1)
- Dünne Schichten (1)
- E. coli (1)
- EC nanomaterial definition (1)
- EDS-TM002 (1)
- ELISA (1)
- EMPIR nPSize (1)
- EMPIR project (1)
- EPICS (1)
- EPMA (Electron Probe Microanalysis) (1)
- EU (1)
- EXAFS (1)
- Ectoine hydration (1)
- Editorial (1)
- Education (1)
- Elastin (1)
- Elastomer (1)
- Electric Safety Interlock (1)
- Electrical Paramters (1)
- Electrical Properties (1)
- Electrical conductivity (1)
- Electrical properties (1)
- Electrical thin layers (1)
- Electrocatalytic Water Splitting (1)
- Electrochemical Degradation (1)
- Electrochemical Titration (1)
- Electrochemical catalysts (1)
- Electrochemical sensing (1)
- Electrochemical treatment (1)
- Electromagnetic radiation (1)
- Electromagnetic theories (1)
- Electron Probe Microanalysis (1)
- Electron Probe Microanalysis (EPMA) (1)
- Electron backscattering diffraction (EBSD) (1)
- Electron beam-induced fragmentation (1)
- Electron density map (1)
- Electron probe microanallysis (EPMA) (1)
- Electron probe microanalysis (1)
- Electron spectroscopy (1)
- Electron tomography (1)
- Electronic, Optical and Magnetic Materials (1)
- Electrons (1)
- Electrospun fibers (1)
- Electrospun nanocomposite fiber (1)
- Elektronisches Laborbuch (1)
- Ellipsometric porosimetry (1)
- Ellipsometrie (1)
- Emission enhancement (1)
- Encapsulation (1)
- Endpoints (1)
- Energiedissipation im Kontakt (1)
- Energy materials (1)
- Engineered nanomaterials (1)
- Environmental Chemistry (1)
- Epoxi nanocomposites (1)
- Epoxy conversion degree (1)
- Epoxy-Anhydrid Duroplast (1)
- Escherichia coli (1)
- Estrogenic activity of plastic nanoparticles (1)
- Etofenprox (1)
- European Metrology Network (1)
- European Metrology Network for Advanced Manufacturing, Strategic Research Agenda (1)
- European funding strategies (1)
- Ex-situ (1)
- Exchange length (1)
- Exfoliation (1)
- Experiment tracking (1)
- Experimental traceability (1)
- Expert system (1)
- Extracellualr vesicles (1)
- Extracellular matrix (1)
- F pili (1)
- FAIRification (1)
- FLASH effect (1)
- FTIR spectroscopy (1)
- Fabrication parameters (1)
- Fe (1)
- Fe-Ni (1)
- Fe2O3 nanoparticles (1)
- FeNi nanoparticles (1)
- FeNi thin film (1)
- Femtosecond laser-processing (1)
- Fermi resonance (1)
- Ferrihydrite (1)
- Ferumoxytol (1)
- Fiber toxicology (1)
- Field of view (1)
- Field sensor (1)
- Filled rubbers (1)
- Filled thermosets and plastics (1)
- Finite element analysis (1)
- Finite-difference time-domain calculations (FDTD) (1)
- Fire Retardant (1)
- Fityk (1)
- Flame retardant (1)
- Flammability (1)
- Flexural rigidity (1)
- Flourescence (1)
- Fluorescence intensity ratio (1)
- Fluorescence microscopy (1)
- Fluorescence quantum yield (1)
- Fluorescence spectroscopy (1)
- Fluorescent glasses (1)
- Fluorescent indicator (1)
- Fluorescent label (1)
- Fluorides (1)
- Fluorolytic sol-gel synthesis (1)
- Focused Ion Beam (1)
- Focussed ion beam (1)
- Food Science (1)
- Force distance curves (1)
- Force-distance curves (1)
- Force-distance-curve (1)
- Form factor (1)
- Forschungsstrategie (1)
- Free electron laser (FEL) (1)
- Freeze casting (1)
- Fresnoit (1)
- Frozen state photopolymerization (1)
- Fullerene (1)
- Fullerite (1)
- Fully aromatic frameworks (1)
- Functional fatigue (1)
- Functional group analysis (1)
- Functional properties (1)
- Functionalized Nanomaterials (1)
- Functionalized nano- and microparticles (1)
- Functionalized nanographene (1)
- Functionalized silica and polymeric particles (1)
- Gadolinium (1)
- Gamma (1)
- Gamma ray (1)
- Gas separation membranes (1)
- Gas sorption (1)
- Gastrointestinal barrier (1)
- Gated hybrid material (1)
- Gel (1)
- General Chemistry (1)
- General Medicine (1)
- Geology (1)
- Git (1)
- Glass Ceramic (1)
- Glass ceramic (1)
- Glass transition temperature (1)
- Glass-ceramic (1)
- Glow-discharge optical emission spectroscopy (1)
- Gold Nanoparticle (1)
- Gold nanoclusters (1)
- Gold-Nanopartikel (1)
- Governance (1)
- Grafting (1)
- Grain orientation (1)
- Granulometrie (1)
- Graphen Oxide (1)
- Graphene /-oxide (1)
- Graphene funcionalisation (1)
- Graphene functionalisation (1)
- Graphene functionalization (1)
- Graphene related materials (1)
- Graphene related two-dimensional materials (GR2M) (1)
- Graphene template (1)
- Graphene-based polyglycerol sulfates (1)
- Graphene-related 2D materials (1)
- Graphhene (1)
- Graphs (1)
- Green synthesis (1)
- Grenzfläche als Material (1)
- Größe (1)
- Größenbestimmung (1)
- Guanidine receptor (1)
- Gypsum' SAXS (1)
- HEA (1)
- Hard X-ray photoelectron spectroscopy (1)
- Heat maps (1)
- Heat-resistant nickel alloys (1)
- Hematite (1)
- Heterogeneous catalysis (1)
- Hexagonally-arranged nano-protrusions (1)
- Hierarchical porosities (1)
- Hierarchical structures (1)
- Hierarchically porous (1)
- High Resolution (1)
- High pressure (1)
- High-resolution (1)
- High-resolution transmission electron microscopy (1)
- High-throughput (1)
- High-throughput measurements (1)
- History (1)
- Holistic experiment approaches (1)
- Holzschutzmittel (1)
- Homogeneous deposition (1)
- Human antibodies (1)
- Human factor (1)
- Human influence (1)
- Hybrid metrology measurement (1)
- Hydrodynamics (1)
- Hydrogen Generation (1)
- Hydrogenated nanostructures (1)
- Hydrothermal synthesis (1)
- Hygiene (1)
- Hyperbranched (1)
- Hyperspectral imaging (1)
- ICP-OES (1)
- ILC (1)
- IR (1)
- IR oxide (1)
- IR spectroscopy (1)
- IR spectroscopy; conductometry (1)
- ISO 21363 (1)
- ISO 23173 (1)
- ISO/TC 201 (1)
- ISO/TC 202 Microbeam Analysis (1)
- ISO/TC229 (1)
- ISOGScope (1)
- Identification (1)
- ImAFM (1)
- Image Segmentation (1)
- Image manipulation (1)
- Images (1)
- Imaging Ellipsometry (1)
- Imaging ellipsometry (1)
- Imaging surface chemical analysis (1)
- Imaging techniques (1)
- Immobilisierung (1)
- Immobilization (1)
- Immunoaffinity extraction (1)
- Immunpräzipitation (1)
- Implant material (1)
- In situ (1)
- In situ Atomic Force Microscopy (AFM) (1)
- In situ synthesis (1)
- In vivo imaging (1)
- In-situ scattering (1)
- Indenter area function (1)
- Indium Tin Oxide (1)
- Industrial and Manufacturing Engineering (1)
- Industrial application (1)
- Inelastic background (1)
- Inelastic neutron scattering (1)
- Inflammation (1)
- Influenza A virus (1)
- Infrared nano AFM (1)
- Infrastructure (1)
- Insecticide (1)
- Instrument automation (1)
- Instrument compliance (1)
- Instrument control (1)
- Instrumentation utilization (1)
- Inter-laborator comparison (1)
- Inter-laboratory comparisons (1)
- Intercomparability (1)
- Interlaboratory (1)
- Interlaboratory comparability (1)
- Interlaboratory comparisons (1)
- Interlabority comparison (1)
- Intermixing (1)
- Intermodulation (1)
- Intermodulation-AFM (1)
- Interpenetrating polymer networks (1)
- Intrinsic OER activity (1)
- Iodine (1)
- Ion beam erosion Sectioning (1)
- Ion beam therapy (1)
- Iridium oxide (1)
- Iron (1)
- Iron carbide (1)
- Iron nanoparticles (1)
- Iron nanophases (1)
- Iron nitride (1)
- Irreversible adsorption (1)
- JNP (1)
- JNP AdvManuNet (1)
- K+ doped (1)
- K-rich Birnessite (K0.45MnO2) (1)
- Knowledge (1)
- Kunststoff (1)
- LET (1)
- LEVASIL 50/50 (1)
- LL equation (1)
- Label (1)
- Laboratory methodology (1)
- Landau Lifshitz Gilbert equation (1)
- Landau de-Gennes analysis (1)
- Lanthanide(III) (1)
- Lanthanides (1)
- Large number of participants (1)
- Laser (1)
- Laser Metal Deposition (LMD) (1)
- Laser damage (1)
- Laser direct writing (1)
- Laser light scattering (1)
- Laser nanostructuring (1)
- Laser technology (1)
- Laser writing (1)
- Laser-Materialbearbeitung (1)
- Laser-induced Periodic Surface Structures (LIPSS) (1)
- Laser-induced amorphization (1)
- Laser-induced micro- and nanostructures (1)
- Laser-induced nanostructures (1)
- Laser-induced pariodic surface structures (1)
- Laser-induced periodic surface structueres (LIPPS) (1)
- Laser-induced periodic surface structures (1)
- Laser-induzierte periodische Oberflächen-Nanostrukturen (1)
- Laser-induzierte periodische Oberflächenstrukturen (1)
- Laser-modified surface (1)
- Lateral dimensions (1)
- Lateral flow assay (1)
- Lateral flow test (1)
- Layer Materials (1)
- Layer system (1)
- Layered manganese oxide (1)
- Lead-free (1)
- Legionella (1)
- Leichtbau (1)
- Lichtstreuung (1)
- Lifetime analysis (1)
- Ligand exchange (1)
- Ligand quantification (1)
- Lignin (1)
- Linux (1)
- Liquid-liquid-phase-separation (1)
- Literature survey (1)
- Llifetime (1)
- Lonic liquid (1)
- Lorenz transmission electron microscopy (1)
- Low Reynolds number swimmers (1)
- Low-loading (1)
- Lubricant additives (1)
- Luminescence lifetime measurments (1)
- Luminescent lifetime (1)
- Luminescent materials (1)
- MCNP (1)
- MIC (1)
- MNP production technique (1)
- MPI (1)
- MPLS (1)
- MRT (1)
- Macrophage (1)
- Magic-sized cluster (1)
- Magnet coupling (1)
- Magnetic (1)
- Magnetic Nanoparticles (1)
- Magnetic anisotropy (1)
- Magnetic beads (1)
- Magnetic interacion (1)
- Magnetic nanoparticle (1)
- Magnetic resonance imaging (1)
- Magnetic swimmers (1)
- Magnetization dynamics (1)
- Magnetron Sputtering (1)
- Martin Seah (1)
- Mass spectrometry (1)
- Material chemistry (1)
- Material defects (1)
- Material-binding Peptides (1)
- Materials Chemistry (1)
- Materials Design (1)
- Materials and Processes Data Reusability (1)
- Materials science (1)
- Matrix (1)
- Matter reorganization (1)
- Matter reorganization theories (1)
- Me-TiO2 (1)
- Measurement methodology (1)
- Measurement science (1)
- Mechanical testing (1)
- Median lethal energy deposit (1)
- Medical implants (1)
- Mesocrystal (1)
- Mesoporous Materials (1)
- Mesoporous SiO2-CaO nanoparticles (1)
- Mesoporous iridium-titanium mixed oxides (1)
- Mesoporous particles (1)
- Mesoporous phosphate-based glasses (1)
- Meta material (1)
- Metadata (1)
- Metadata collection (1)
- Metadata structuring (1)
- Metal (1)
- Metal carbides (1)
- Metal fluorides (1)
- Metal organic frameworks (1)
- Metal-organic frameworks (1)
- Metal-semiconductor (1)
- Metal–organic framework (1)
- Metasurface (1)
- Methodology development (1)
- Methos comparision (1)
- Metrics (1)
- Metrological traceability (1)
- Metrology in Chemistry and Biology (1)
- Micelle (1)
- Micro- and Nanoplastics (1)
- Microarray (1)
- Microarray printing (1)
- Microbial adhesions (1)
- Microfabrication (1)
- Microfluids (1)
- Microorganism (1)
- Microparticle (1)
- Microparticles (1)
- Microplastic reference materials (1)
- Microstructure evolution (1)
- Microtribology (1)
- Microwave synthesis (1)
- Microwave-assisted synthesis (1)
- Mie resonances (1)
- Mikrostrukturen (1)
- Mitochondria (1)
- Mixed metal oxide (1)
- Model (1)
- Modulus (1)
- Molecular Dynamics (1)
- Molecular Mobility (1)
- Molecular mobility (1)
- Molecularly imprinted polymers (1)
- Monomer (1)
- Monte carlo (1)
- Monte-Carlo (1)
- Morpho-chemical characterization (1)
- Motor controller (1)
- Multi-photon light structuring (1)
- Multi-resistant bacteria (1)
- Multi-sample analysis (1)
- Multi-scale (1)
- Multi-scale measurements (1)
- Multicolored (1)
- Multifunctional nanoparticles (1)
- Multiphoton laser structuring (1)
- Multivalency (1)
- Mussel inspired materials (1)
- Mussel-inspired adhesives (1)
- Mussel-inspired coating (1)
- Mussel-inspired materials (1)
- Mutual calibration (1)
- NFDI (1)
- NIR-II Imaging (1)
- NIR-II fluorescence (1)
- NIRII (1)
- NaCl-Methode (1)
- Nafion 117 (1)
- Naica (1)
- Nanaoparticle (1)
- Nano CRM (1)
- Nano Characterisation (1)
- Nano characterization (1)
- Nano material (1)
- Nano screening (1)
- Nano structure (1)
- Nano-ceramic-additive-manufacturing photoresin (1)
- Nano-characterisation (1)
- Nano-object (1)
- Nano-related data (1)
- Nano-risk assessment (1)
- NanoCAM (1)
- NanoValid (1)
- Nanoanalysis (1)
- Nanoanalytics (1)
- Nanobiointerfaces (1)
- Nanocasting (1)
- Nanocomposite fibers (1)
- Nanocubes (1)
- Nanodiamant (1)
- Nanodielectrics (1)
- Nanodosimetry (1)
- Nanofiller (1)
- Nanokomposit (1)
- Nanomaterial Properties (1)
- Nanomaterial analysis (1)
- Nanomaterial categorisation (1)
- Nanomaterial definition (1)
- Nanomaterial design (1)
- Nanomaterial legislation (1)
- Nanomaterial properties (1)
- Nanomaterial regulation (1)
- Nanomechanical charecteisation (1)
- Nanomechanical properties (1)
- Nanon (1)
- Nanoparticle Characterization (1)
- Nanoparticle characterization (1)
- Nanoparticle size distribution (1)
- Nanoparticle size measurement (1)
- Nanoparticles Synthesis and Characterization (1)
- Nanoparticular TiO2 (Anatase) (1)
- Nanopipette modification (1)
- Nanoplatelet (1)
- Nanoplatform (1)
- Nanoplattform (1)
- Nanoporous (1)
- Nanopowder (1)
- Nanopropous materials (1)
- Nanorisk Governance (1)
- Nanosafety services (1)
- Nanoscale (1)
- Nanoscale luminescent reporters (1)
- Nanoscale measurements (1)
- Nanoscience (1)
- Nanosensors (1)
- Nanosilica (NS) (1)
- Nanosilver (1)
- Nanostrcutures (1)
- Nanostructural analysis (1)
- Nanostructured FeOx films (1)
- Nanostrukturen (1)
- Nanotechnologie (1)
- Nanotechnologies (1)
- Nanotoxicity (1)
- Nanotribology (1)
- Nanowear (1)
- Native oxide layer (1)
- Nd excitation (1)
- Near-field spectroscopy (1)
- Neel wall (1)
- Network (1)
- Neuartige Materialien (1)
- Neural Networks (1)
- Neutron Scattering (1)
- Neutron imaging (1)
- Next Generation Sequencing (1)
- Ni (1)
- Ni-Mn-Ga (1)
- Nichtrostender Stahl (1)
- Nickel (1)
- Nile Red (1)
- Nitrene[2+1]cycloaddition (1)
- Nitrogen (1)
- Nnano particle (1)
- Noble metal nanoparticles (1)
- Non-classical crystallization (1)
- Non-destructive ambient analysis (1)
- Non-destructive testing (1)
- Non-spherical nanoparticles (1)
- Non-thermally coupled levels (1)
- Non-vitriolic iron-gall inks (1)
- Nonclassical crystallization (1)
- Nonlinear lithography (1)
- Normung (1)
- Nuclear Energy and Engineering (1)
- Nucleus (1)
- Numerical simulations (1)
- OECD TG (1)
- OECD TG 125 (1)
- OH (1)
- OMS (1)
- Oberflächenanalytik (1)
- Oberflächenintegrität (1)
- Oberflächenmesstechnik (1)
- Oberflächenmodifikation (1)
- Oberflächenpotential (1)
- Oberflächensteifigkeit (1)
- Ontologies (1)
- Open data on zenodo (1)
- Operating Procedure (1)
- Optical Assays (1)
- Optical analysis (1)
- Optical birefringence (1)
- Optical constants (1)
- Optical detection (1)
- Optical flow (1)
- Optical measurement technology (1)
- Optical measurements (1)
- Optical near field (1)
- Optical probes (1)
- Optical properties (1)
- Optical scattering (1)
- Optical temperature sensing (1)
- Optical tweezers (1)
- Optically active surfaces (1)
- Oral uptake (1)
- Ordered mesoporous carbon (1)
- Organic phosphates (1)
- Organic–inorganic nanostructures (1)
- Origami (1)
- Osteogenesis (1)
- Oxygen evolution reaction (OER) (1)
- Oxygen sensing (1)
- Oxygen sensitive (1)
- P25 (1)
- PC characterisation (1)
- PES (1)
- PFAS (1)
- PH (1)
- PH probe (1)
- PVDF-Based membrane (1)
- Paint (1)
- Pair distribution function (1)
- Paper mills (1)
- Paramagnetism (1)
- Parameter correlation. (1)
- Participatory Approach (1)
- Particle accretion (1)
- Particle architecture (1)
- Particle scatterin simulations (1)
- Particle sensors (1)
- Particle shape (1)
- Particle size determination (1)
- Particle transfer (1)
- Particle, imaging (1)
- Partikeldurchmesser (1)
- Partikelgröße (1)
- Partikelgrößenbestimmung (1)
- Partikelkonzentration (1)
- Passivation shell (1)
- Pd(II) (1)
- Peem (1)
- Pelletization (1)
- Peptide binder (1)
- Peptides (1)
- Perfluorooctanoic Acid (PFOA) (1)
- Performance check (1)
- Perovskites (1)
- Pesticide (1)
- Pflanzenvirus (1)
- Phage Display (1)
- Phase transition (1)
- Phase transitions (1)
- Phenothrin (1)
- Phosphinine (1)
- Photodynamic therapy (1)
- Photoelectrochemistry (1)
- Photoluminescence quantum yield (1)
- Photon bunching (1)
- Photonics (1)
- Photons (1)
- Photooxidation (1)
- Photophysic (1)
- Photopolymer (1)
- Photoreforming (1)
- Photostability (1)
- Physical and theoretical chemistry (1)
- Physicochemical characterization (1)
- Pigments (1)
- Pitfalls (1)
- Plant virus (1)
- Plasma deposition (1)
- Plasmon enhancement (1)
- Plasmon resonance (1)
- Plasmonic nanofocusing (1)
- Plasmonic nanofocusing spectroscopy (1)
- Plastic reference materials (1)
- Plastics (1)
- Plastikstrategie (1)
- Platinum-ruthenium colloid (1)
- Polarimetry (1)
- Pollution (1)
- Polybutadiene/chloroprene (1)
- Polydispersity (1)
- Polyethylene (1)
- Polyethylene Glycol (1)
- Polyethylene glycol (1)
- Polyethylene glycol diacrylate (1)
- Polyethylene terephthalate (1)
- Polymer analysis/characterization (1)
- Polymer based Nanocomposites (1)
- Polymer electrolyte fuel cell (1)
- Polymer foils (1)
- Polymer nanocomposite (1)
- Polymer-binding Peptides (1)
- Polymer-ceramic mixtures (1)
- Porous carbon (1)
- Porous carbons (1)
- Porphyrin (1)
- Position of carboxylate group (1)
- Post-modification by L-cysteine (1)
- Postfluorination (1)
- Powder (1)
- Powder X-ray diffraction (1)
- Powder processing (1)
- Power Electronics (1)
- Power electronics (1)
- Pphotophysics (1)
- Practical aspects (1)
- Pre-standardisation (1)
- Preceramic polymer (1)
- Precipitation (1)
- Preparation (1)
- Primer (1)
- Principle component analysis (1)
- Procedure (1)
- Prodrug antibiotic (1)
- Production (1)
- Proficiency test (1)
- Propolis (1)
- Protection (1)
- Protein structure (1)
- Prürfrichtlinie (1)
- Pt(II) (1)
- Pump-probe (1)
- Purification (1)
- Pycnometry (1)
- Pyrethroid (1)
- QNMR (1)
- QUASES (1)
- Qantum yield (1)
- Quality assurcance (1)
- Quality control (1)
- Quality infrastructure (1)
- Quantitative surface chemical analysis (1)
- Quantum Dots (1)
- Quantum Yields (1)
- Quantum do (1)
- Quantum rod (1)
- Quartz nanopipettes (1)
- Quarzglas (1)
- RBE (1)
- REACH (1)
- RNA (1)
- Radiation (1)
- Radiation protection (1)
- Radical Scavenge (1)
- Radioactive NP (1)
- Raman spectroscopy (1)
- Ratiometric (1)
- Ratiometric Sensors (1)
- Real time growth control (1)
- Real-time infrared spectroscopy (1)
- Recycling (1)
- Recycling-by-design (1)
- Reference Method (1)
- Reference Nanomaterials (1)
- Reference methods (1)
- Reference nanomaterials (1)
- Reference nanoparticles (1)
- Reference particles (1)
- Reference procedures (1)
- Reference products (1)
- Reference standards (1)
- Reference structure (1)
- Referenzdaten (1)
- Regeneration (1)
- Regional workshop (1)
- Reibungsreduktion (1)
- Reinforcement (1)
- Release (1)
- Release kinetics (1)
- Reliabiilty (1)
- Reliable characterization (1)
- Renewable Energy (1)
- Renewable energy (1)
- Repelling surface coatings (1)
- Reporter (1)
- Representative morphology modeling (1)
- Research Data Management (1)
- Resins (1)
- Resonance (1)
- Reverse microemulsion (1)
- Ridis amorphous fraction (1)
- Ripples (1)
- Risk Governance (1)
- Risk asessment (1)
- Risstrajektorie (1)
- Robocasting (1)
- Robotic synthesis (1)
- Robotic-supported synthesis (1)
- Roughness (1)
- Round Robin (1)
- Rreference material (1)
- Röntgenrefraktion (1)
- SARS-CoV 2 (1)
- SARS-CoV2 inhibitor (1)
- SBA-16 (1)
- SDLs (1)
- SKPM (1)
- SMPS (1)
- SRA (1)
- SSB (1)
- SSbD (1)
- STEM-in-SEM (1)
- STEM-in-SEM (TSEM) (1)
- STL file input (1)
- SWIR photoluminescence (1)
- Sabatier (1)
- Saccharide sensing (1)
- Safe by design (1)
- Safe-by-design (1)
- Safer by design (1)
- Sall-angle scattering (1)
- Sample peparation (1)
- Saphir (1)
- Saponite (1)
- Scannig probe microscope (1)
- Scanning Auger Spectroscopy (1)
- Scanning Electron Microscopy (1)
- Scanning Kelvin Probe Force Microscopy (SKPFM) (1)
- Scanning Probe Microscopy (1)
- Scanning Probe methods (1)
- Scanning micro-X-ray fluorescence (1)
- Scanning probe measurements (1)
- Scanning probe microscopy (1)
- Scanning transmission X-ray microscopy (STXM) (1)
- Scattering pattern (1)
- Scattering pattern simulation (1)
- Schlangenbohne (1)
- Schmiermittel (1)
- SchwarzP cells (1)
- Scientific misconduct (1)
- Screening (1)
- Screening method (1)
- Scribal corrections (1)
- Second-generation high temperature superconductor technology (1)
- Secondary Ion Mass Spectrometry (1)
- Self-degrading (1)
- Self-driving Labs (1)
- Semantic Interoperability (1)
- Semiconductor materials (1)
- Semiconductor nanocrystals (1)
- Semiconductur (1)
- Sensing; temperature (1)
- Sensitization (1)
- Sensor Materials (1)
- Separation membranes (1)
- Sequential Learning (1)
- Shape-controlled (1)
- Shape-memory alloys (1)
- Shortwave infrared (1)
- Si-Ge (1)
- SiO2 Nanoparticle (1)
- Sialic acid (1)
- Silanisation (1)
- Silica Nanoparticles (1)
- Silica coating (1)
- Silica particles (1)
- Silica- and Polystyrene Particles (1)
- Silica- and polystyrene particles (1)
- Silicon nanoparticles (1)
- Silver indium sulfide (1)
- Simulations (1)
- Single asperity (1)
- Single asperity contact (1)
- Single cell-ICP-ToF-MS (1)
- Single enhancement (1)
- Single molecule (1)
- Single particle-ICP-ToF-MS (1)
- Single-dot spectroscopy (1)
- Single-particle measurements (1)
- Singlet oxygen (1)
- Size and size distribution (1)
- Size measurement (1)
- Size measurements (1)
- Slicers (1)
- Sliding (1)
- Slurry (1)
- Small angle x-ray scattering (1)
- Small-Angle X-ray Scattering (1)
- Small-angle X-ray Scattering (1)
- Small-angle x-ray scattering (1)
- Small-area XPS (1)
- Smartphone readout device (1)
- Software UNIFIT 2022 (1)
- Sol-gel (1)
- Sol-gel synthesis (1)
- Solar cell (1)
- Solar cells (1)
- Solarpur (1)
- Solid state (1)
- Solid-binding Peptides (1)
- Sonochemical synthesis (1)
- SpICP-MS (1)
- Speciation analysis (1)
- Specific Surface Area (BET) (1)
- Specific heat spectroscopy (1)
- Specific surface (1)
- Spectroscopy / Instrumentation (1)
- Spectroscopy / Theory (1)
- Spektroskopie (1)
- Spezifische Oberfläche (1)
- Spin (1)
- Stabilization (1)
- Standard Operation Procedures (1)
- Standard operation procedures (1)
- Standardarbeitsanweisung (1)
- Standardarbeitsanweisungen (1)
- Standardized check (1)
- Stepwise growth (1)
- Stochastic Landau Lifshitz equation (1)
- Strain measurement (1)
- Strategic Research Agenda (SRA), (1)
- Strontium titanate (1)
- Structural characterisation (1)
- Structural color (1)
- Structural precision (1)
- Structure activity relationships (1)
- Structure–property correlation (1)
- Sulfated materials (1)
- Superconductivity (1)
- Superelasticity (1)
- Superparamagnetism (1)
- Surface Activation (1)
- Surface Analysis Working Group (1)
- Surface Analytics (1)
- Surface Chemical Transformation (1)
- Surface Chemistry (1)
- Surface Modification (1)
- Surface characterization (1)
- Surface chemisttry (1)
- Surface coating (1)
- Surface engineering (1)
- Surface functional group quantification (1)
- Surface group (1)
- Surface groups (1)
- Surface modified nano- and microparticles (1)
- Surface morphology and chemistry (1)
- Surface plasmon polaritons (1)
- Surface plasmon resonance (1)
- Surface properties (1)
- Surface regeneration (1)
- Surface superconductivity (1)
- Surface-induced Melting (1)
- Surface-initated grafting (1)
- Surfaces, Coatings and Films (1)
- Sustainability and the Environment (1)
- Sustainable-by-Design (1)
- Suzuki-Miyaura coupling (1)
- Swarming (1)
- Switch (1)
- Synergistic effects (1)
- Synergy (1)
- Synthesis library (1)
- Systems architecture (1)
- TGA-MS (1)
- TMDCs (1)
- TOPAS-nBio (1)
- TRL (1)
- TSEM (1)
- Tafel Plot (1)
- Tag (1)
- Targeted nanoparticle (1)
- Temparatur modulated Flash DSC (1)
- Temperature effects (1)
- Temperature modulated DSC (1)
- Temperature modulated differential scanning calorimetry (1)
- Terminal functional groups (1)
- Termites (1)
- Test artifact (1)
- Test structure (1)
- Testguideline (1)
- Theoretical modelling (1)
- Theranostics (1)
- Therapeutic antibodies (1)
- Therapy (1)
- Thermal annealing (1)
- Thermal coupling energy level (1)
- Thermal desorption mass spectrometry (1)
- Thermally coupled levels (1)
- Thermogravimetry (1)
- Thermoset composition (1)
- Thermosets (1)
- Thetaevolve (1)
- Thick shells (1)
- Thickness measurements (1)
- Thin Layers (1)
- Thin film (1)
- Thin film analysis (1)
- Thin film systems (1)
- Thin magnetic films (1)
- Thin mesoporous films (1)
- Thiol-ene click chemistry (1)
- Thiols (1)
- Threshold (1)
- Thumor therapy (1)
- Ti oxide (1)
- Ti-6Al-4V alloy (1)
- Ti6Al4V alloys (1)
- TiO2 D540 nanoparticles (1)
- TiO2 PVP (1)
- TiO2 nanoparticle (1)
- TiO2 nanoparticles (1)
- Time of Flight - Secondary ion mass spectrometry (1)
- Time-of-Flight Secondary Ion Mass Spectrometry (1)
- Time-of-flight secondary ion mass spectrometry (1)
- Time-offlight secondary ion mass spectrometry (ToF-SIMS) (1)
- Time-resolved analysis (1)
- Time-resolved coherent scattering (1)
- Titanium (1)
- Titanium alloys (1)
- Titanium oxide (1)
- ToF SIMS (1)
- Tools (1)
- Tools to combat scientific misconduct (1)
- Topas-nbio (1)
- TopasMC (1)
- Torah scrolls (1)
- Total scattering (1)
- Toxicity (1)
- Traceability derivation (1)
- Traceable nanoparticle size measurements; (1)
- Transition electron microscopy (1)
- Transition metal dichalcogenide (1)
- Transmission Electron Microscopy (1)
- Transmission electron microsocpy (1)
- Transmission function IERF (1)
- Transparent conductive Oxides (1)
- Transport limitations (1)
- Trastuzumab (1)
- Trends (1)
- Triazine (1)
- Triggered (1)
- Trinkwasser (1)
- Triplet-triplet annihilation (1)
- Tungsten (1)
- Twin orientation relationship (1)
- Two photon polymerization (1)
- Two-Photon Polymerization (1)
- Two-dimensional hexagonal boron nitride(h-BN) (1)
- Two-photon adsorption (1)
- Two-photon polymerisatio (1)
- Two-photon-polymerization (1)
- Type-I pyrethroids (1)
- UV Weathering (1)
- UV-curing (1)
- UiO (1)
- Ultrakurzpuls-Laser (1)
- Ultrakurzpuls-Laserbearbeitung (1)
- Ultraschall (1)
- Ultraschallunterstütztes Fräsen (1)
- Ultrashort lasers (1)
- Uncertainty budget (1)
- UpConversion (1)
- Upconverion (1)
- Upconversion luminescence (1)
- Upconverstion (1)
- Upscaling (1)
- VMAAS (1)
- VRFB (1)
- Van der Waals forces (1)
- Vanadium speciation (1)
- Variable excitation (1)
- Vernetzung (1)
- Verschleißreduktion (1)
- Video (1)
- Vigna unguiculata (1)
- Virucidality (1)
- Viskosität (1)
- Vitriolic iron-gall inks (1)
- Volatiles from thermosets (1)
- Volcano plot (1)
- Vulcanization (1)
- Wastewater (1)
- Water (1)
- Water analysis (1)
- Water dispersibility (1)
- Water electrolysis (1)
- Water filtration (1)
- Water management (1)
- Waxs (1)
- Wear particles (1)
- Werkstoffe (1)
- Wet dispersion (1)
- White light interferometric microscopy (1)
- White light interferometry microscopy (1)
- White-light Interference Microscopy (1)
- White-rot fungi (1)
- Wide-bandgap semiconductors (1)
- Wide-range (1)
- Wirksumme (1)
- Wood protection (1)
- Workflow (1)
- Workflows (1)
- X-Ray Spectroscopy (1)
- X-Ray analysis (1)
- X-ray Photoelectron Spectroscopy (1)
- X-ray Absorption Spectroscopy (1)
- X-ray Fluorescence (1)
- X-ray Photoelectron Spectroscopy (XPS) (1)
- X-ray generation (1)
- X-ray instrumentation (1)
- X-ray microscopy (1)
- X-ray microspectroscopy (1)
- X-ray photoelectron spectroscopy (XPS) (1)
- X-ray production efficiency (1)
- X-ray spectrometer (1)
- X-rays (1)
- XCT (1)
- XPS spctroscopy (1)
- XRM (1)
- XUV scattering (1)
- Yb(III) complex (1)
- Young´s modulus (1)
- Yttria stabilized zirconia (1)
- Yttria-stabilized zirconia (1)
- ZIF-8 (1)
- Zeolitic Imidazolate Frameworks (1)
- Zero wear (1)
- Zinc phosphate (1)
- Zirconium (1)
- ZnO (1)
- ZnO nanoparticles (1)
- ZnSe (1)
- ZrO2 nanoparticles (1)
- [MMIM]+[DMP]− (1)
- abasic side (1)
- aggregation-induced dual emission (AIDE) (1)
- analytical service (1)
- anion-exchange (1)
- antibody (1)
- attraktive Wechelwirkung (1)
- automation (1)
- bacteria (1)
- bacteria detection (1)
- base loss (1)
- bended arrow of time (1)
- bioactive (1)
- bioimaging (1)
- biomaterials (1)
- bone (1)
- clustered nanoparticles (1)
- dispersion (1)
- dsDNA (1)
- electron microscopy (1)
- flow cytometry (1)
- fluorescence microscopy (1)
- fluorescence standards (1)
- gamma ray (1)
- graphene related 2D materials (1)
- immunoseparation (1)
- instrument utilization (1)
- laboratory automation (1)
- laboratory management (1)
- lifetime (1)
- magnetic nanoparticle (1)
- metadata collection (1)
- method (1)
- nm films (1)
- organic dyes (1)
- particle (1)
- particle size determination (1)
- qNMR (1)
- quality assurcance (1)
- quantum dot (1)
- quantum yield (1)
- radiolysis (1)
- research efficiency (1)
- sample preparation (1)
- screening tes (1)
- shape control (1)
- single cell-ICP-ToF-MS (1)
- single particle-ICP-ToF-MS (1)
- stl code (1)
- surface group analysis (1)
- synthesis (1)
- temeprature dependent exchange length (1)
- time-temperature equivalent formulation (1)
- time-temperature superposition principle (1)
- total scattering (1)
- transmission mode (1)
- wrapping (1)
- µ-XRF (1)
- Äquivalenzdurchmesser (1)
Organisationseinheit der BAM
- 6 Materialchemie (656)
- 6.1 Oberflächen- und Dünnschichtanalyse (345)
- 1 Analytische Chemie; Referenzmaterialien (184)
- 1.2 Biophotonik (159)
- 6.6 Physik und chemische Analytik der Polymere (134)
- 6.5 Synthese und Streuverfahren nanostrukturierter Materialien (129)
- 6.2 Material- und Oberflächentechnologien (90)
- 5 Werkstofftechnik (61)
- 4 Material und Umwelt (46)
- 5.4 Multimateriale Fertigungsprozesse (33)
Paper des Monats
- ja (15)
Simulational tools are applied to investigate the physical properties of nanoparticles.
For the description of radioactive gold nanoparticles, particles scattering simulations are performed with the Geant4 monte carlo simulation toolkit.
The temperature dependent behaviour of the magnetization dynamics of different magnetic nanoparticles are simulated with the object oriented micormagnetic framework (OOMMF).
The coherent exchange of optical near fields between two neighbouring dipoles plays an essential role in the optical properties, quantum dynamics and thus the function of many naturally occurring and artificial nanosystems. These interactions are challenging to quantify experimentally. They extend over only a few nanometres and depend sensitively on the detuning, dephasing and relative orientation (that is, the vectorial properties) of the coupled dipoles. Here, we introduce plasmonic nanofocusing spectroscopy to record coherent light scattering spectra with 5 nm spatial resolution from the apex of a conical gold nanotaper.
The apex is excited solely by evanescent fields and coupled to plasmon resonances in a single gold nanorod. We resolve resonance energy shifts and line broadenings as a function of dipole distance and relative orientation. We demonstrate how These phenomena arise from mode couplings between different vectorial components of the interacting optical near fields, specifically from the coupling of the nanorod to both transverse and longitudinal polarizabilities of the taper apex.
The performance of functional coatings and adhesively joined hybrid components relies strongly on the stability of the polymer-metal interface. With the increasing utilization of multi-material structures in the automotive and aerospace industry, it is of great scientific and technical interest to understand the processes leading to interface degradation and to develop novel strategies to increase corrosion and delamination resistance.
The aim of this project is to develop thin epoxy-based films on aluminium alloy AA2024-T3 as a model system and to investigate their interfacial stability under corrosive and coupled corrosive-mechanical load. Electrochemical and spectroscopic methods were used for the characterisation of the film properties and in situ corrosion experiments were performed by means of AFM. The deformation properties of the aluminium alloy and the model coatings were investigated by means of scanning Kelvin probe force microscopy (SKPFM) utilizing the integrated tensile stage.
The presentation will give a brief overview of the capabilities of the new AFM setup to foster future collaborations and summarize our work on the interface stability of model coatings.
This report describes a standard operation procedure for dispersion of nanomaterials in liquids prior to toxicological or ecotoxicological testing. Main factors, who determine the state of agglomeration and aggregation of ENMs after dispersion are specific energy input, particle concentration and fluid composition. The method was validated in two round robin tests, where two typical nanomaterials (a nanopowder and a nanodispersion) were investigated. One main result arising out of the data comparison was that only those participants, who were able to follow the instructions in the SOPs completely, received similar results regarding particle size and zeta potential. The SOP is easy to adapt for other types of nanomaterials. The results provide the standardization process and were presented at DIN working group.
A new method for top‐down, one‐pot, gram‐scale production of high quality nanographene by incubating graphite in a dilute sodium hypochlorite solution at only 40 °C is reported here. The produced sheets have only 4 at% oxygen content, comparable with nanographene grown by chemical vapor deposition. The nanographene sheets are covalently functionalized using a nondestructive nitrene [2+1] cycloaddition reaction that preserves their π‐conjugated system. Statistical analyses of Raman spectroscopy and X‐ray photoelectron spectroscopy indicate a low number of sp3 carbon atoms on the order of 2% before and 4% after covalent functionalization. The nanographene sheets are significantly more conductive than conventionally prepared nanographene oxide, and conductivity further increases after covalent functionalization. The observed doping effects and theoretical studies suggest sp2 hybridization for the carbon atoms involved in the [2+1] cycloaddition reaction leading to preservation of the π‐conjugated system and enhancing conductivity via n‐type doping through the bridging N‐atom. These methods are easily scalable, which opens the door to a mild and efficient process to produce high quality nanographenes and covalently functionalize them while retaining or improving their physicochemical properties.
Preactivation crosslinking – An efficient method for the oriented immobilization of antibodies
(2019)
Crosslinking of proteins for their irreversible immobilization on surfaces is a proven and popular method. However, many protocols lead to random orientation and the formation of undefined or even inactive by-products. Most concepts to obtain a more targeted conjugation or immobilization requires the recombinant modification of at least one binding partner, which is often impractical or prohibitively expensive. Here a novel method is presented, which is based on the chemical preactivation of Protein A or G with selected conventional crosslinkers. In a second step, the antibody is added, which is subsequently crosslinked in the Fc part. This leads to an oriented and covalent immobilization of the immunoglobulin with a very high yield. Protocols for Protein A and Protein G with murine and human IgG are presented. This method may be useful for the preparation of columns for affinity chromatography, immunoprecipitation, antibodies conjugated to magnetic particles, permanent and oriented immobilization of antibodies in biosensor systems, microarrays, microtitration plates or any other system, where the loss of antibodies needs to be avoided, and maximum binding capacity is desired. This method is directly applicable even to antibodies in crude cell culture supernatants, raw sera or protein-stabilized antibody preparations without any purification nor enrichment of the IgG. This new method delivered much higher signals as a traditional method and, hence, seems to be preferable in many applications.
Preactivation Crosslinking - An Efficient Method for the Oriented Immobilization of Antibodies
(2019)
Crosslinking of proteins for their irreversible immobilization on surfaces is a proven and popular method. However, many protocols lead to random orientation and the formation of undefined or even inactive by-products. Most concepts to obtain a more targeted conjugation or immobilization requires the recombinant modification of at least one binding partner, which is often impractical or prohibitively expensive. Here a novel method is presented, which is based on the chemical preactivation of Protein A or G with selected conventional crosslinkers. In a second step, the antibody is added, which is subsequently crosslinked in the Fc part. This leads to an oriented and covalent immobilization of the immunoglobulin with a very high yield. Protocols for Protein A and Protein G with murine and human IgG are presented. This method may be useful for the preparation of columns for affinity chromatography, immunoprecipitation, antibodies conjugated to magnetic particles, permanent and oriented immobilization of antibodies in biosensor systems, microarrays, microtitration plates or any other system, where the loss of antibodies needs to be avoided, and maximum binding capacity is desired. This method is directly applicable even to antibodies in crude cell culture supernatants, raw sera or protein-stabilized antibody preparations without any purification nor enrichment of the IgG. This new method delivered much higher signals as a traditional method and, hence, seems to be preferable in many applications.
If the particle size decreases, the ratio of surface area to volume increases considerably. This provides benefits for all surface-driven processes that run faster or at lower temperatures than larger particles. However, handling and characterization of the nanopowders are much more difficult. Particularly polydisperse powders with irregular shape, as grinding products, represent a challenge. Granulometry in the submicron and nanoscale often leads to incorrect results without knowledge of particle morphology.
This presentation demonstrates potentials of using the volume-specific surface area (SV or VSSA) in the granulometric characterization of nanopowders, for instance, correlations between the volume-specific surface area and the median particle size are discussed considering the particle morphology and the model of the logarithmic normal distribution.
Moreover, the presentation deals with the optimal dispersion of nanopowders during sample preparation. Indirect ultrasound device with defined cooling was developed to prevent both contamination by sonotrode abrasion and sample changes by heat.
Successful granulometric characterization of nanopowders demands both improved dispersion technology and very often an effective combination of two or more measurement methods.
Dose enhancement by gold nanoparticles (AuNP) was shown to increase the biological effectiveness of radiation damage in biomolecules and tissue. Most of the current studies focus on external beam therapy on combination with AuNP. Here we present a Monte-Carlo study (Geant4) to characterise radioactive AuNP. Radioactive 198 Au emits beta and gamma rays and is considered for applications with solid tumours. To effectively apply 198 AuNP their energy deposit characteristics have to be determined in terms of intrinsic and extrinsic properties e.g. AuNP diameter, AuNP density, and their clustering behaviour. After each decay process, the energy deposit, inelastic scattering events, kinetic energy spectrum of secondary particles within the AuNP themselves and in a spherical target volume of water up to 1 μm radius were determined. Simulations were performed for AuNP radii ranging from 2.5 nm to 20 nm radius, different cluster sizes and densities. The results show an increase of the energy deposit in the vicinity of the AuNP up to 150 nm. This effect nearly vanishes for distances up to one micron. For the case of AuNP clusters and the same activity, the enhancement of the energy deposit increases with the relative gold mass percentage and therefore can be adjusted by changing AuNP radius or clustering behaviour.
In this work, a novel boehmite (BA)-embedded organic/inorganic nanocomposite coating based on cycloaliphatic epoxy oligosiloxane (CEOS) resin was fabricated applying UV-induced cationic polymerization. The main changes of the material behavior caused by the nanofiller were investigated with regard to its photocuring kinetics, thermal stability, and glass transition. The role of the particle surface was of particular interest, thus, unmodified nanoparticles (HP14) and particles modified with p-toluenesulfonic acid (OS1) were incorporated into a CEOS matrix in the concentration range of 1–10 wt.%. Resulting nanocomposites exhibited improved thermal properties, with the glass transition temperature (Tg) being shifted from 30 °C for unfilled CEOS to 54 °C (2 wt.% HP14) and 73 °C (2 wt.% OS1) for filled CEOS. Additionally, TGA analysis showed increased thermal stability of samples filled with nanoparticles. An attractive interaction between boehmite and CEOS matrix influenced the curing. Real-time infrared spectroscopy (RT-IR) experiments demonstrated that the epoxide conversion rate of nanocomposites was slightly increased compared to neat resin. The beneficial role of the BA can be explained by the participation of hydroxyl groups at the particle surface in photopolymerization processes and by the complementary contribution of p-toluenesulfonic acid surface modifier and water molecules introduced into the system with nanoparticles.
Dose enhancement by gold nanoparticles (AuNP) was shown to increase the biological effectiveness of radiation damage in biomolecules and tissue. Most of the current studies focus on external beam therapy on combination with AuNP. Here we present a Monte-Carlo study (Geant4) to characterise radioactive AuNP. Radioactive ¹⁹⁸Au emits beta and gamma rays and is considered for applications with solid tumours. To effectively apply ¹⁹⁸AuNP their energy deposit characteristics have to be determined in terms of intrinsic and extrinsic properties e.g. AuNP diameter, AuNP density, and their clustering behaviour. After each decay process, the energy deposit, inelastic scattering events, kinetic energy spectrum of secondary particles within the AuNP themselves and in a spherical target volume of water up to 1 μm radius were determined. Simulations were performed for AuNP radii ranging from 2.5 nm to 20 nm radius, different cluster sizes and densities. The results show an increase of the energy deposit in the vicinity of the AuNP up to 150 nm. This effect nearly vanishes for distances up to one micron. For the case of AuNP clusters and the same activity, the enhancement of the energy deposit increases with the relative gold mass percentage and therefore can be adjusted by changing AuNP radius or clustering behaviour.
In this study, we systematically investigate the decay characteristics of upconversion luminescence (UCL) under anti-Stokes excitation through numerical simulations based on rate-equation models. We find that a UCL decay profile generally involves contributions from the sensitizer’s excited-state lifetime, energy transfer and cross-relaxation processes. It should thus be regarded as the overall temporal response of the whole upconversion system to the excitation function rather than the intrinsic lifetime of the luminescence emitting state. Only under certain conditions, such as when the effective lifetime of the sensitizer’s excited state is significantly shorter than that of the UCL emitting state and of the absence of cross-relaxation processes involving the emitting energy level, the UCL decay time approaches the intrinsic lifetime of the emitting state. Subsequently, Stokes excitation is generally preferred in order to accurately quantify the intrinsic lifetime of the emitting state. However, possible cross-relaxation between doped ions at high doping levels can complicate the decay characteristics of the luminescence and even make the Stokesexcitation approach fail. A strong cross-relaxation process can also account for the power dependence of the decay characteristics of UCL.
Considerations for nanomaterial identification of powders using volume-specific surface area method
(2019)
The EC’s recommendation for a definition of nanomaterial (2011/696/EU) should allow the identification of a particulate nanomaterial based on the number-based metric criterion according to which at least 50% of the constituent particles have the smallest dimension between 1 and 100 nm. However, it has been recently demonstrated that the implementation of this definition for regulatory purposes is conditioned by the large deviations between the results obtained by different sizing methods or due to practical reasons such as high costs and time-consuming.
For most measurement methods for particle size determination it is necessary to initially disperse the particles in a suitable liquid. However, as the particle size decreases, the adhesion forces increase strongly, making it more difficult to deagglomerate the particles and to assess accurately the result of this process. Therefore, the success of the deagglomeration process substantially determines the measurement uncertainty and hence, the comparability between different methods.
Many common methods such as dynamic light scattering (DLS), centrifugal liquid sedimentation (CLS) or ultrasound attenuation spectroscopy (US) can give good comparable results for the size of nanoparticles, if they are properly separated and stabilized (e.g. in reference suspensions).
In order to avoid the use of hardly available and expensive methods such as SEM / TEM for all powders, an agglomeration-tolerant screening method is useful.
One of the measurement methods well suited to probe the size of particulate powder is the determination of the volume-specific surface area (VSSA) by means of gas adsorption as well as skeletal density. The value of 60 m2/cm3 corresponding to spherical, monodisperse particles with a diameter of 100 nm constitutes the threshold for decisioning if the material is a nano- or non-nanomaterial. The identification of a nanomaterial by VSSA method is accepted by the EU recommendation.
However, the application of the VSSA method was associated also with some limitations. The threshold of 60 m2/cm3 is dependent on the particle shape, so that it changes considerably with the number of nano-dimensions, but also with the degree of sphericity of the particles. For particles containing micro-pores or having a microporous coating, false positive results are induced. Furthermore, broad particle size distributions made necessary to additionally correct the threshold. Based on examples of commercially available ceramic powders, the applicability of the VSSA approach was tested in relation with SEM and TEM measurements. The introduction of a correction term for deviations from sphericity and further additions improved the applicability of VSSA as a screening method.
The Scope of the Workshop was to provide a forum for discussion on progress in development, characterisation and application of reference nanomaterials. Results of recently finsihed national and international research projects have been presented. Moreover, the need for future developments have been addressed.
Attendees of teh Workshop were expected to be experts from academia, research institutes, regulatory bodies and industry working or interested in the area of reference nanomaterials.
The following structure of Workshop was planned: the main focus of the first day was on reference material needs and development, while teh second day was focussed on reference materials characterisation and standardisation.
Over 111 participants frm 13 countries and teh European Joint Research Centre have regsitered for the Workshop with 16 platform presentations and 42 poster contributions grouped in 2 sessions and 10 topical areas.
A summary of the observations, analysis and conclusions of the Workshop is made including an overview table of links to information on existing reference nanomaterials.
An overview of the activities in the field of surface and microbeam analysis at BAM-6.1 is given with focus on physico-chemical characterization at the nanoscale. Ideas of potential joint activities are presented: structural and chemical analysis of graphene, deposition techniques for nanoparticles, EBSD on steel for a broader range of methods, instruments and types of steel, soft X-ray Analysis of low-Z materials, analysis of mesoporous thin films, etc.
Das EMPIR-Förderprogramm wird kurz erläutert und laufende Projekte aus der Nanotechnologie werden vorgestellt. Der Schwerpunkt liegt auf Standardisierungsprojekten, die gemeinsam mit ISO/TC 229 'Nanotechnologies' und CEN/TC 352 'Nanotechnologies' zu neuen Normen führen sollten. Als Beispiel für laufende Nanotechnologie-Projekte mit Koordination aus Deutschland werden MagNaStand (PTB) und nPSize (BAM) gegeben.
Superglassy polymers with a large fractional free volume have emerged as novel materials with a broad range of applications, especially in the field of membrane separations. Highly permeable addition-type substituted polynorbornenes with high thermal resistance and chemical stability are among the most promising materials. The major obstacle for extending the practical membrane application is their strong tendency to physical aging, leading to a partial decline in their superior transport performance over time. In the present study, broadband dielectric spectroscopy with complementary X-ray scattering techniques were employed to reveal changes in microporous structure, molecular mobility, and conductivity by systematic
comparison of two polynorbornenes with different numbers of trimethylsilyl side groups. Their response upon heating (aging) was compared in terms of structure, dynamics, and charge transport behavior. Furthermore, a detailed analysis of the observed
Maxwell−Wagner−Sillars polarization at internal interfaces provides unique information about the microporous structure in the
solid films. The knowledge obtained from the experiments will guide and unlock potential in synthesizing addition-type polynorbornenes with versatile properties.
New Focus On Boehmite-Reinforced Nanocomposites Molecular Approach With Advanced FTIR-Techniques
(2019)
By FTIR-study it was possible to proof a chemical reaction between boehmite and the hardener of anhydride cured epoxy resins. Future studies can assume that the chemical environment of the resin system is changed in the surrounding of boehmite nanoparticles. This highly affects especially localized properties.
Der vorliegende Vortrag gibt einen Überblick über Probenpräparationen mit der Focused Ion Beam (FIB) für AFM-basierte Untersuchungsverfahren. Anhand zweier Beispiele wird gezeigt, wie ionenstrahlpolierte Lamellen aus Halbleiter-Schichtsystemen elektrisch leitfähig auf Substrate platziert werden, so dass in-situ und in-operando Messungen mit Scanning Microwave Microscope (SMM) bzw. Spectroscopic infrared scanning near-field optical microscope (IR-SNOM) durchgeführt werden können.
Nanocomposites are extremely versatile due to their physicochemical properties, which differ significantly from bulk homopolymers. One of the inorganic nanomaterials which are increasingly used as a filler in polymer matrices is boehmite, typically used as an inexpensive flame retardant. Here, it is used as a nanofiller in polycarbonate and polyamide, expecting to improve their mechanical properties. For industrial use boehmite is obtained by the solvothermal method, resulting in a layered nanomaterial, whereas naturally it occurs as single crystals with the size of <100µm. In this work we are obtaining and isolating boehmite crystals by a bottom-up method, in which a reaction between aluminum nitride and sodium hydroxide. Obtaining boehmite as microcrystals is necessary for its analysis and characterization, as well as to investigate its interaction with polymer matrices at the polymer/particle interface. Here, the obtained particles in polymer matrices are characterized with differential scanning calorimetry and thermogravimetry analysis.
Nanocomposites are extremely versatile due to their physicochemical properties, which differ significantly from bulk homopolymers. One of the inorganic nanomaterials which are increasingly used as a filler in polymer matrices is boehmite, typically used as an inexpensive flame retardant. Here, it is used as a nanofiller in polycarbonate and polyamide, expecting to improve their mechanical properties. For industrial use boehmite is obtained by the solvothermal method, resulting in a layered nanomaterial, whereas naturally it occurs as single crystals with the size of <100µm. In this work we are obtaining and isolating boehmite crystals by a bottom-up method, in which a reaction between aluminum nitride and sodium hydroxide. Obtaining boehmite as microcrystals is necessary for its analysis and characterization, as well as to investigate its interaction with polymer matrices at the polymer/particle interface. Here, the obtained particles in polymer matrices are characterized with differential scanning calorimetry and thermogravimetry analysis.
Synthetic microswimmers mimicking biological movements at the microscale have been developed in recent years. Actuating helical magnetic materials with a homogeneous rotating magnetic field is one of the most widespread techniques for propulsion at the microscale, partly because the actuation strategy revolves around a simple linear relationship between the actuating field frequency and the propeller velocity.
However, full control of the swimmers’ motion has remained a challenge. Increasing the controllability of micropropellers is crucial to achieve complex actuation schemes that, in turn, are directly relevant for numerous applications. However, the simplicity of the linear relationship limits the possibilities and flexibilities of swarm control. Using a pool of randomly shaped magnetic microswimmers, we show that the complexity of shape can advantageously be translated into enhanced control. In particular, directional reversal of sorted micropropellers is controlled by the frequency of the actuating field. This directionality change is linked to the balance between magnetic and hydrodynamic forces. We further show an example of how this behavior can experimentally lead to simple and effective sorting of individual swimmers from a group. The ability of these propellers to reverse swimming direction solely by frequency increases the control possibilities and is an example for propeller designs, where the complexity needed for many applications is embedded directly in the propeller geometry rather than external factors such as actuation sequences.
Mesoporous phosphates are a group of nanostructured materials with promising applications, particularly in biomedicine and catalysis. However, their controlled synthesis via conventional template-based routes presents a number of challenges and limitations. Here, we show how to synthesize a mesoporous Magnesium phosphate with a high surface area and a well-defined pore structure through thermal decomposition of a crystalline struvite (MgNH4PO4·6H2O) precursor. In a first step, struvite crystals with various morphologies and sizes, ranging from a few micrometers to several millimeters, had been synthesized from supersaturated aqueous solutions (saturation index (SI) between 0.5 and 4) at ambient pressure and temperature conditions. Afterwards, the crystals were thermally treated at 70–250 °C leading to the release of structurally bound water (H2O) and ammonia (NH3). By combining thermogravimetric analyses (TGA), scanning and transmission electron microscopy (SEM, TEM), N2 sorption analyses and small- and wide-angle X-ray scattering (SAXS/WAXS) we show that this decomposition process results in a pseudomorphic transformation of the original struvite into an amorphous Mg-phosphate. Of particular importance is the fact that the final material is characterized by a very uniform mesoporous structure with 2–5 nm wide pore channels, a large specific surface area of up to 300 m2 g−1 and a total pore volume of up to 0.28 cm3 g−1. Our struvite decomposition method is well controllable and reproducible and can be easily extended to the synthesis of other mesoporous phosphates. In addition, the so produced mesoporous material is a prime candidate for use in biomedical applications considering that Magnesium phosphate is a widely used, non-toxic substance that has already shown excellent biocompatibility and biodegradability.
While today, engineers can choose from a wide range of rheology modifying admixtures, in some parts of the world, these are difficult to access, due to their complex processing. However, alternatives can be bio-based polymers such as polysaccharides from various sources. These are easily accessible all over the world, do not demand for complicated processing, and typically they are more sustainable than many established materials, which are crude oil-based.
The paper presents the effects of acacia gum, cassava starch and the gum of triumfetta pendrata A. Rich on the rheological performance of cementitious systems. It is shown that acacia gum can be as efficient as polycarboxylate based superplasticisers, cassava starch can reduce the yield stress slightly with little effect on the plastic viscosity, and the gum of triumfetta pendrata A. Rich increases the thixotropy of cement pastes with plasticizing polymers significantly.
While today, engineers can choose from a wide range of rheology modifying admixtures, in some parts of the world, these are difficult to access, due to their complex processing. However, alternatives can be bio‐based polymers such as polysaccharides from various sources. These are easily accessible all over the world, do not demand for complicated processing, and typically they are more sustainable than many established materials, which are crude oil‐based.
The paper presents the effects of acacia gum, cassava starch and the gum of triumfetta pendrata A. Rich on the rheological performance of cementitious systems. It is shown that acacia gum can be as efficient as polycarboxylate based superplasticisers, cassava starch can reduce the yield stress slightly with little effect on the plastic viscosity, and the gum of triumfet ta pendrata A. Rich increases the thixotropy of cement pastes with plasticizing polymers significantly.
Structural design and application have always been linked to the compressive strength of concrete as the main relevant criterion. This was justifiable in the past, where concrete consisted of water, ordinary Portland cement and aggregates, but this concept is no longer relevant for modern and more sustainable cement and concrete.
Despite these new developments, existing standards, guidelines and academic curricula have not been much updated and are still used worldwide. There is a need to change this situation by proper education of the users.
This overview describes the challenges that arise at a user Level from the higher complexity of modern concrete, and defines needs and requirements for enhanced applicability of sustainable concrete concepts.
Furthermore, recommendations are given on how better concrete practice can be communicated to all the involved parties, from civil and design engineers to constructors and site-appliers on the construction site.
UV-curing coatings are nowadays widely used due to their unique advantages. High-quality coatings can be obtained at short curing times and low temperatures so that thermal stress to the substrate is minimised. Photocured Cycloaliphatic-Epoxy Oligosiloxane (CEO) resin was reported to be used as encapsulation material for organic electronics. However, further reinforcement of CEO film properties is desired to achieve requested device lifetime.
In this work we introduced Boehmite nanoparticles (BA) into CEO matrix in order to modify the film properties and study the main changes of the material behaviour with regard to its photocuring kinetics, thermal stability and glass transition. Particular interest was focused on the role of particle surface in nanocomposite properties. Hence, BA particles without (HP14) and with organic surface modifier (OS1) at different loadings (up to 10 wt%) were applied in this study. Morphology investigation with SEM operated in transmission mode showed good BA dispersion forming network-like structure. At the same time, distribution of particles differed for HP14 and OS1 as a result of different interaction in CEO-solvent-particles system. CEO structure obtained via non-hydrolytic sol-gel reaction was verified by 13C and 29Si NMR. In situ monitoring of film curing was performed using RT-IR spectroscopy. No significant modification of final convention degree with particle incorporation was observed in contrast to considerable decrease of curing efficiency reported previously for similar system by Esposito et al.,2008. Further, cured hybrid nanocomposite films were analysed by TGA and DSC, which revealed impact of surface modifier on film thermal properties.
Organic-inorganic nanostructured materials have drawn much attention over the past decade, particularly due to their versatile and outstanding properties. Possessing the properties between those of polymers and those of glasses, siloxane-based resins are non-toxic, easy to synthesize and process hybrid materials, that hold a promising potential in the field of advanced coatings.
Photocurable resins are nowadays widely used as coatings due to their unique advantages. In particular, cationic ring-opening curing is not inhibited by oxygen, leads to low degree of shrinkage and superior adhesion. The most important, it enables production of high-quality coatings within short exposure times without applying temperature, thus, minimizing the presence of the thermal stress in the substrate. Photocured Cycloaliphatic-Epoxy Oligosiloxane (CEO) resin was reported to be used as encapsulation material for organic electronics. However, further reinforcement of CEO properties is desired to achieve requested device lifetime. One of the common approaches to improve material characteristics is by embedding inorganic nanoparticles into polymer matrix. It has been shown that the resulted nanocomposites exhibit enhanced functional properties included but not limited by optical, mechanical, thermal and barrier ones.
In this work we focused on the incorporation of Boehmite nanoparticles (BA) into CEO matrix as a tool to strengthen the film properties and to study the main changes occurred in the material behavior with regard to its photocuring kinetics, thermal stability and glass transition. Particular interest was focused on the role of particle surface in nanocomposite properties. Hence, BA particles without (HP14) and with organic surface modifier (OS1) at different loadings
(up to 10 wt%) were applied in this study. Morphology investigation with SEM operated in transmission mode showed good BA dispersion forming
network-like structure. At the same time, distribution of particles differed for HP14 and OS1 as a result of different interaction in CEO-solvent-particles system. CEO structure obtained via non-hydrolytic sol-gel reaction was verified by 13C and 29Si NMR. In situ monitoring of film curing was performed using
RT-IR spectroscopy. A slight increase of final convention degree with particle incorporation was observed in contrast to the considerable decrease of curing efficiency reported previously for similar system. Further, the cured hybrid nanocomposite films were analyzed by TGA and DSC, which revealed impact of surface modifier on thermal stability and glass transition temperature.
Coating materials are nowadays often required to deliver not only sufficient barrier performance and suited optical appearance but a broad range of other functional properties. The incorporation of inorganic nanoparticles (NPs) is known to improve many key characteristics and provide new functionalities in polymer materials. Presented work aims to prepare and characterize an organic-inorganic coating material designed to bring together advantageous properties of hybrid materials and reinforcement effect delivered from the inorganic NPs embedment.
Siloxane-based hybrid resins hold great advantages as coating materials as their properties can be tuned between those of polymers and those of glasses, thus, the compositions with superior thermal and mechanical properties can be achieved. We used Cycloaliphatic Epoxy Oligosiloxane (CEOS) resin as a polymeric matrix where the network formation was achieved by UV induced cationic polymerisation. Boehmite Alumina (BA) nanoparticles were added to CEOS resin as a reinforcing agent and resultant material was processed into films either by bar-coating or by spin-coating depending on further characterization procedure. Two different types of BA NPs, hydrophilic and organophilic, were used in order to assess the impact of particles surface on the resin characteristics. CEOS synthesis by condensation reaction was confirmed using 13C and 29Si NMR. Changes in CEOS photocuring process, resulting from particles incorporation, were monitored by real-time IR spectroscopy. At the same time, the thermal behaviour was evaluated by DSC and TGA methods. Morphology of the coatings was investigated by means of SEM operated in transmission mode.
It was observed that BA presence increased the epoxy conversion degree and glass transition temperature. Material formulations providing best film characteristics were determined with regard to the particle type and loading. Compared to the hydrophilic nanoparticles, organophilic BA NPs yield superior overall performance of the foils.
Thermosetting materials are gaining increasing attention in many structural composite applications. However, the incorporation of inorganic nanoparticles (NPs) into polymer matrix is a promising approach to enhance their functional characteristics, and thus, to enable the development of thermosets advanced application. It has been shown that Boehmite Alumina (BA) used as nanofillers can improve different parameters of polymers. This NPs can be easily tailored enabling desirable interactions with a big range of polymers. However, the overall effect of nanofiller depends on many factors, therefore, making it hard to predict the resulted performance of nanocomposites. In the current contribution we would like to discuss the impact of Boehmite NPs on two different epoxy resin nanocomposite systems with the focus on the possible influence mechanisms of this nanofiller.
As the first system, UV curable Cycloaliphatic-Epoxy Oligosiloxane (CEOS) resin/Boehmite nanocomposites were investigated by FTIR, TGA, DSC and T-SEM. It was observed that incorporation of BA leads to the reinforcement of glass transition (Tg) and overall thermal stability indicating the attractive interactions between BA and CEOS network. In addition, an increase in epoxy conversion of CEOS was concluded for nanocomposites assuming that particles are involved in UV polymerisation processes.
The second epoxy/Boehmite nanocomposite is based on the bisphenol-A-diglycidyl ether (DGEBA) cured with methyl tetrahydrophtalic acid anhydride (MTHPA). Thermomechanical as well as nanomechanical properties of this material were investigated by DMTA and IR spectroscopy and the advanced Intermodulation AFM, respectively. In contrast to the first system, it was found that BA leads to a decrease of Tg and crosslink density of the polymer while the young’s modulus of the composite and local stiffness of polymer matrix increase significantly.
As a result, the versatile role of Boehmite was detected depending on the investigated systems. Based on the obtained results, the parameters indicating property-efficient epoxy/Boehmite system are suggested.
Nachdem Jahrzehnte die Grenzfläche zwischen Kohlefaser und Duroplastmatrix optimiert wurde liegt das Augenmerk heute auf der Polymermatrix selbst. Diese lässt sich hinsichtlich ihres Elastizitätsmoduls und ihrer Bruchfestigkeit verbessern, indem Nanopartikel aus Böhmit (AlOOH) eindispergiert werden. Der Vortrag geht auf integrale und hochauflösend-bildgebende Methoden ein die ein Verständnis der komplexen Zusammenhänge ermöglichen. Nach einer chemischen in-situ Analyse des Aushärtvorgangs, aus welchem sich die Bedeutung der externer Parameter ablesen lässt, werden diverse hochauflösende, neue Methoden der Rasterkraftmikroskopie (AFM) eingeführt. Der lokalen Bestimmung des E-Moduls der Nanopartikel folgen Ausführungen zum temperaturabhängigen Chemismus des Böhmits, der während der Aushärtung Wasser freisetzt. Die hochauflösende Bestimmung der Oberflächenpotentiale, der Steifigkeit, der attraktiven Kräfte zwischen Spitze und Probe sowie der Energiedissipation im Kontakt stellen auf der Nanoskala eine komplexe Datenquelle dar, die auf der Makroskala einer Ergänzung bedarf: Durch Kombination von dynamisch-mechanisch-thermischer Analyse einerseits und Kartierung physikalischer Eigenschaften auf der Nanoskala andererseits kann der Zusammenhang zwischen chemischer Steuerung der Netzwerkbildung und den mechanischen Eigenschaften des Nanokomposits geklärt werden. Überraschend ist, dass bei geeigneter Steuerung der lokale E-Modul der Polymermatrix den des Füllstoffs übersteigt. Die Rissfortschrittsenergie wird in Böhmit-modifiziertem Epoxy verbessert absorbiert, die These dazu ist, dass die (010)-Gleitebenen, die nur durch Wasserstoffbrücken zusammen gehalten werden, einigermaßen schadlos geschert werden können. Daraus folgt, dass das System auf der Nanoskala über einen, wenn auch begrenzten, Selbstheilmechanismus verfügt. Zudem wird durch die hohe Heterogenität der Steifigkeit und Energiedissipation des Nanokomposits eine Risstrajektorie vielfach umgelenkt und somit früher gestoppt. Ergebnisse dieses Vortrags stammen aus einer Zusammenarbeit innerhalb des DFG-Forscherverbundes FOR2021 „Wirkprinzipien nanoskaliger Matrixadditive für den Faserverbundleichtbau“.
Optical spectroscopy – Techniques, instrumentation, and typical molecular and nanoscale reporters
(2018)
Different types of optical spectroscopies are introduced with special emphasis on method-inherent limitations and reliable instrument calibration and performance validation. In addition, different classes of molecular and nanocrystalline emitters are presented and the underlying photophysical processes are briefly described.
Different types of optical spectroscopies are introduced with special emphasis on method-inherent limitations and reliable instrument calibration and performance validation. In addition, procedures for the determination of spectroscopic key parameters like the photoluminescence quantum yield are presented including required instrument calibrations and material-specific effects related to certain emitters.
Surface functionalization of 2D- and 3D-supports and nanomaterials are nowadays at the core of many applications of functional materials in the life and material sciences. Examples range from membranes and microarrays over bead-based assays, immunoseparation, and next generation sequencing to nanometer-sized optical reporters, nanosensors, and magnetic and optical contrast agents. Typically performed functionalization procedures include silanization and grafting reactions with reactive monomers to introduce functional groups like amino or carboxylic acid groups and the attachment of ligands like polyethylene glycol (PEG) molecules and biomolecules such as peptides, proteins, and DNA.[1-3]
We present here a versatile concept to quantify the number of bioanalytically relevant functional groups like carboxyl, amino, and aldehyde moieties through the specific binding and subsequent release of small reporter molecules such as fluorescent dyes and non-fluorescent chromophores utilizing cleavable linkers or the formation of cleavable bonds as a reversible covalent labeling strategy. This is representatively demonstrated for different types of nano- and microparticles with different labeling densities of carboxyl, amino, and aldehyde groups. This strategy enables to separate the signal-generating molecule from the bead surface, thereby circumventing uncertainties associated with light scattering, binding-induced changes in reporter fluorescence, and fluorescence quenching dye-dye interactions on crowded material surfaces.[1-3] Moreover, the reporters are chosen to be detectable with different analytical methods as prerequisite for straightforward validation via method compari-sons and mass balances. Applications of these assays and multimodal cleavable probes range from a quantitative comparison of bead batches and process control to a qualitative prediction of the coupling efficiencies in bioconjugation reactions.
We show that complex physical and chemical interactions between boehmite nanoparticles and epoxy drastically affect matrix properties, which in the future will provide tuning of material properties for further optimization in applications from automotive to aerospace. We utilize intermodulation atomic force microscopy (ImAFM) for probing local stiffness of both particles and polymer matrix. Stiff particles are expected to increase total stiffness of nanocomposites and the stiffness of polymer should remain unchanged. However, ImAFM revealed that stiffness of matrix in epoxy/boehmite nanocomposite is significantly higher than unfilled epoxy. The stiffening effect of the boehmite on epoxy also depends on the particle concentration. To understand the mechanism behind property alteration induced by boehmite nanoparticles, network architecture is investigated using dynamic mechanical thermal analysis (DMTA). It was revealed that although with 15 wt% boehmite nanoparticles the modulus at glassy state increases, crosslinking density of epoxy for this composition is drastically low.
Understanding the interaction between nanoparticles and the matrix and the properties of interphase is crucial to predict the macroscopic properties of a nanocomposite system. Here, we investigate the interaction between boehmite nanoparticles (BNPs) and epoxy using different atomic force microscopy (AFM) approaches. We demonstrate benefits of using multifrequency intermodulation AFM (ImAFM) to obtain information about conservative, dissipative and van der Waals tip-surface forces and probing local properties of nanoparticles, matrix and the interphase.
We utilize scanning kelvin probe microscopy (SKPM) to probe surface potential as a tool to visualize material contrast with a physical parameter, which is independent from the mechanics of the surface. Combining the information from ImAFM stiffness and SKPM surface potential results in a precise characterization of interfacial region, demonstrating that the interphase is softer than epoxy and boehmite nanoparticles. Further, we investigated the effect of boehmite nanoparticles on the bulk properties of epoxy matrix. ImAFM stiffness maps revealed the significant stiffening effect of boehmite nanoparticles on anhydride-cured epoxy matrix. The energy Dissipation of epoxy Matrix locally measured by ImAFM shows a considerable increase compared to that of neat epoxy. These measurements suggest a substantial alteration of epoxy structure induced by the presence of boehmite.
Overview about the surface initiated microstructure formation in glass surfaces. Samples which are exposed to a temperature treatment, can develop a crystalline microstructure above Tg at the surface. These separated crystals can be preferably oriented towards the surface of the sample. First experiments about the origin of these orientation phenomenon as well as the potentially causing mechanisms are presented and discussed within the presentation.
Mandatory for the comparison of different emitter classes and the rational design of the next generation of molecular and nanoscale reporters are reliable and quantitative photoluminescence measurements. This is of special relevance for all fluorescence applications in the life and material sciences. In the following, procedures for the determination of this spectroscopic key parameter are presented including pitfalls and achievable uncertainties and material-specific effects related to certain emitter classes are addressed.
Optical spectroscopic studies of the influence of size, particle architecture, and surface chemistry of different types of photoluminescent nanocrystals with emission in the vis/NIR will be presented including semiconductor quantum dots and lanthanide-based upconversion nanoparticles. This will include the photophysics of these materials assessed with steady state and time-resolved fluorometry on the ensemble and single particle level and concepts for the quantification of surface groups at nanomaterials with optical methods using cleavable probes and catch-and-release assays.
Nanomaterials are used in many different applications in the material and life sciences. Examples are optical reporters, barcodes, and nanosensors, magnetic and optical contrast agents, and catalysts. Due to their small size and large surface area, there are also concerns about their interaction with and uptake by biological systems. This has initiated an ever increasing number of cyctoxicity studies of nanomaterials of different chemical composition and surface chemistry, but until now, the toxicological results presented by different research groups often do not address or differ regarding a potential genotoxicity of these nanomaterials. This underlines the need for a standardized test procedure to detect genotoxicity.1,2
Aiming at the development of fast, easy to use, and automatable microscopic methods for the determination of the genotoxicity of different types of nanoparticles, we assess the potential of the fluorometric γH2AX assay for this purpose. This assay, which can be run on an automated microscopic detection system, relies on the determination of DNA double strand breaks as a sign for genotoxicity.3 Here, we present first results obtained with broadly used nanomaterials like CdSe/CdS and InP/ZnS quantum dots as well as iron oxide, gold, and polymer particles of different surface chemistry with previously tested colloidal stability. These studies will be also used to establish nanomaterials as positive and negative genotoxicity controls or standards for assay performance validation for users of this fluorometric genotoxicity assay. In the future, after proper validation, this microscopic platform technology will be expanded to other typical toxicity assays.
References. (1) Landsiedel, R.; Kapp, M. D.; Schulz, M.; Wiench, K.; Oesch, F., Reviews in Mutation Research 2009, 681, 241-258. (2) Henriksen-Lacey, M.; Carregal-Romero, S.; Liz-Marzán, L. M., Bioconjugate Chem. 2016, 28, 212-221. (3) Willitzki, A.; Lorenz, S.; Hiemann, R.; Guttek, K.; Goihl, A.; Hartig, R.; Conrad, K.; Feist, E.; Sack, U.; Schierack, P., Cytometry Part A 2013, 83, 1017-1026.
The phase behavior and molecular ordering of hexakishexyloxy triphenylene (HAT6) DLC under cylindrical nanoconfinement is studied utilizing differential scanning calorimetry (DSC) and dielectric spectroscopy (DS), where cylindrical nanoconfinement is established through embedding HAT6 into the nanopores of anodic aluminum oxide membranes (AAO), and a silica membrane with pore diameters ranging from 161 nm down to 12 nm. Both unmodified and modified pore walls were considered, and in the latter case the pore walls of AAO membranes were chemical treated with n octadecylphosphonic acid (ODPA) resulting in the formation of a 2.2 nm thick layer of grafted alkyl chains. Phase transition enthalpies decrease with decreasing pore size, indicating that a large proportion of the HAT6 molecules within the pores has a disordered structure, which increases with decreasing pore size for both pore walls. In the case of the ODPA modification the amount of ordered HAT6 is increased compared to the unmodified case. The pore size dependencies of the phase transition temperatures were approximated using the Gibbs Thomson equation, where the estimated surface tension is dependent on the molecular ordering of HAT6 molecules within the pores and upon their surface. DS was employed to investigate the molecular ordering of HAT6 within the nanopores. These investigations revealed that with a pore size of around 38 nm, for the samples with the unmodified pore walls, the molecular ordering changes from planar axial to homeotropic radial. However, the planar axial configuration, which is suitable for electronic applications, can be successfully preserved through ODPA modification for most of the pore sizes.
We investigate the nearfield dipole mobility of protein membranes in a wide frequency range from 3 kHz to 10 GHz. The results of our nanoscale dielectric images and spectra of bacteriorhodopsin (bR) reveal Debye relaxations with time constants of τ ∼ 2 ns and τ ∼ 100 ns being characteristic of the Dipole moments of the bR retinal and α-helices, respectively. However, the dipole mobility and therefore the protein biophysical function depend critically on the amount of surface water surrounding the protein, and the characteristic mobility in the secondary structure is only observed for humidity levels <30%. Our results have been achieved by adding the frequency as a second fundamental dimension to quantitative dielectric microscopy. The key elements for the success of this advanced technique are the employed heterodyne detection scheme, the broadband electrical signal source, a high frequency optimized cabling, development of calibration procedures and precise finite element modelling. Our study demonstrates the exciting possibilities of broadband dielectric microscopy for the investigation of dynamic processes in cell bioelectricity at the individual molecular level. Furthermore, the technique may shed light on local dynamic processes in related materials science applications like semiconductor Research or nano-electronics.
Broadband dielectric spectroscopy in the frequency range from 10-1 to 109 Hz is employed to revisit the segmental dynamics of the miscible blend system poly(vinyl methyl ether)/polystyrene (PVME/PS) in dependence on the composition firstly in the bulk state. Here especially the case of high polystyrene concentrations is considered. It is important to note that only the molecular dynamics of PVME segments as affected by PS is observed because the dipole moment of polystyrene is negligible. Three relaxation processes are found which are due to fluctuations of differently constrained or confined PVME segments. The degree of the confinement of PVME segments due to PS is discussed in dependence on the composition.
Further a spatial confinement is considered by investigating thin films of the PVME/PS blend where the film thickness was varied from 100 nm down to 5 nm. Two concentrations of PVME/PS (50/50 wt% and 25/75 wt%) are investigated. To measure nanometer thick films a novel electrode system based on nanostructured electrodes was employed. Nanostructured electrodes can be considered as a cut-edge technology in dielectric spectroscopy. The relaxation spectra of the films showed multiple processes which are discussed in dependence on the film thickness.
The molecular mobility of the highly asymmetric miscible blend poly(vinyl methyl ether)/polystyrene was investigated by broadband dielectric (frequency range 10^-1 Hz – 10^9 Hz) and specific heat spectroscopy (frequency range 10^1 Hz – 10^4 Hz). The dielectric spectra revealed a complex molecular dynamic behavior, where three different relaxation processes were observed. At temperatures below the glass transition temperature an α´-relaxation was found, with an Arrhenius-like temperature dependence of its relaxation rates. It is assigned to localized fluctuations of the confined PVME segments within a frozen glassy matrix dominated by PS. Above the thermal glass transition temperature two processes with a VFT behavior of their relaxation rates were detected called α1- and α2-relaxation, both originating from PVME dipoles fluctuating in PS-rich environments, however with diverse PS concentrations. The relevant length scales for the processes are assumed to be different, corresponding to the Kuhn segment length for the former relaxation and to the CRR for the latter one. The observed multiple glassy dynamics result from spatial local compositional heterogeneities on a microscopic level. Additionally, SHS investigations were performed for the first time for this system, proving an existence of a fourth relaxation process (α3-relaxation) due to the cooperative fluctuations of both PS and PVME segments. The separation between the thermal α3- and dielectric α2-relaxation increases dramatically with increasing polystyrene concentration, proving that the thermal response is dominated by PS.