Chemische Charakterisierung und Spurenanalytik
Filtern
Dokumenttyp
- Vortrag (90)
- Zeitschriftenartikel (72)
- Posterpräsentation (27)
- Forschungsdatensatz (3)
- Forschungsbericht (2)
- Buchkapitel (1)
- Beitrag zu einem Tagungsband (1)
- Preprint (1)
Sprache
- Englisch (156)
- Deutsch (40)
- Mehrsprachig (1)
Schlagworte
- Synchrotron (33)
- BAMline (30)
- Mikroplastik (29)
- TED-GC/MS (25)
- Microplastic (18)
- Microplastics (18)
- XRF (18)
- Mechanochemistry (10)
- TED-GC-MS (9)
- XANES (9)
- MALDI-TOF MS (8)
- Gold (7)
- Machine learning (7)
- Nanoparticle (6)
- Reference material (6)
- Analytik (5)
- Polymer 3R (5)
- XRD (5)
- Analysis (4)
- Automation (4)
- Bayesian Statistics (4)
- In situ (4)
- Pollen (4)
- Polylactide (4)
- Reference materials (4)
- Single cell analysis (4)
- TXRF (4)
- Water (4)
- Archaea (3)
- Coded Aperture (3)
- DNA (3)
- Dosimetry (3)
- Gaussian process (3)
- Machine Learning (3)
- Microbiologically influenced corrosion (3)
- Mikroplastik-Analytik (3)
- Nanoparticles separation capillary electrophoresis asymmetrcial flow field flow fractionation (3)
- Neural network (3)
- Probennahme (3)
- Referenzmaterialien (3)
- SAXS (3)
- Sampling (3)
- Sampling techniques (3)
- Standardisation (3)
- Tire wear (3)
- Trinkwasser (3)
- Affinity Chromatography (2)
- Aktivkohle (2)
- Amperometry (2)
- Analytic (2)
- Artificial Inelligence (2)
- Artificial intelligence (2)
- Asymmetrical flow field flow fractionation (AF4) (2)
- Batteries (2)
- Bayesian Optimization (2)
- Bioimaging (2)
- CXC (2)
- Capillary electrophoresis (2)
- Capillary electrophoresis (CE) (2)
- Certification (2)
- Crystalinity (2)
- D2XRF (2)
- EXAFS (2)
- FPLC (2)
- HPLC (2)
- Harmonisation (2)
- Homogeneity (2)
- ILC (2)
- Immunoassay (2)
- Internal Standard (2)
- Ionization (2)
- Lanthanide (2)
- MALDI TOF MS (2)
- Nanomaterial (2)
- Polymere (2)
- Polymers (2)
- Probenahme (2)
- Quality testing (2)
- Referenzmaterial (2)
- Risk assessment (2)
- SC-ICP-ToF-MS (2)
- Sc-ICP-ToF-MS (2)
- Soil (2)
- Spectroscopy (2)
- Stability (2)
- Standarisierung (2)
- Synthesis (2)
- Thermogravimetrie (2)
- Umwelt (2)
- Wasseraufbereitung (2)
- X-ray fluorescence (2)
- XAFS (2)
- A4F (1)
- AG nanoparticle (1)
- AU nanoparticle (1)
- Absorption spectrometry (1)
- Acidic oxygen evolution reaction (1)
- Acoustic levitation (1)
- Acute myocardial infarction (1)
- Additive (1)
- Additive Manufacturing (1)
- Affinity Extraction (1)
- Affinity Separation (1)
- Amyloid (1)
- Analyse (1)
- Analytical Sciences (1)
- Analytical standards (1)
- Antibodies (1)
- Antibody Purification (1)
- Antikensammlung Berlin (1)
- Application properties (1)
- Archaeometry (1)
- Archäometrie (1)
- Artificial Intelligence (1)
- Aspergillus (1)
- Atomic layer deposition (1)
- Aufbereitung (1)
- Automated Purification (1)
- Barium (1)
- Battery (1)
- Bayes (1)
- Bbeverages (1)
- Beamline (1)
- Bernstorf (1)
- Biological & biomedical applications (1)
- Biomarker (1)
- Biosensor (1)
- Biosynthesis (1)
- Bismuth (1)
- Bisphenol A (1)
- Bone matrix (1)
- Borosilicate Glass (1)
- Böden (1)
- CCQM key comparison (1)
- Calcium monofluoride (1)
- Carboxyl group (1)
- Cardiac troponin (1)
- Cascade filtration (1)
- Catalysts (1)
- Cathode material (1)
- Causes leading to scientific misconduct (1)
- Channel access (1)
- Chemical composition (1)
- Chemical transformation (1)
- Chemiluminescence (1)
- Citizen Science (1)
- Classification (1)
- Cobalt deposition (1)
- Cocoa (1)
- Cocrystal (1)
- Color X-ray Camera (1)
- Column holder (1)
- Comparative test (1)
- Compost (1)
- Concentration step (1)
- Conjugate (1)
- Construction (1)
- Coordination polymers (1)
- Core-shell nanoparticles (1)
- Core/shell nanoparticle (1)
- Corrosion (1)
- Coupling reactions (1)
- Crystallization (1)
- Cyclic voltammetry (1)
- Cyclization (1)
- Cycloparaphenylenes (1)
- Cylic Voltammetry (1)
- DNA strand break (1)
- Data conversion (1)
- Data manipulation (1)
- Debye-Waller parameter (1)
- Deep work (1)
- Degradation (1)
- Density separation (1)
- Depth profile (1)
- Desorption (1)
- Detektion (1)
- Detektion von Mikroplastik (1)
- Diagnosis (1)
- Diagnostic Antibodies (1)
- Digital laboratory (1)
- Digitalization (1)
- Dispersive-XAS (1)
- Dose (1)
- Down Stream Processing (1)
- EPICS (1)
- Ectoine (1)
- Ectoine radiation protection (1)
- Egypt (1)
- Electrocatalysis (1)
- Electrochemistry (1)
- Electrohpresis (1)
- Elektronenmikroskopie (1)
- Emergency (1)
- Endocrine disruptor (1)
- Energy input (1)
- Energy storage (1)
- Environmental analysis (1)
- Environmental impacts (1)
- Epoxy (1)
- Extended X-ray absorption fine structure (1)
- FTIR (1)
- Farbenlehre (1)
- Fenton (1)
- Filter crucible (1)
- Filtration (1)
- Flow injection immunoassay (1)
- Fluorescence (1)
- Fluorine (1)
- Folic acid (1)
- Food safety (1)
- Fraktionierte Filtration (1)
- Framework (1)
- Fundamentals (1)
- Fusarium (1)
- GUI (1)
- Gaussian Process (1)
- General Chemistry (1)
- General Materials Science (1)
- Gilding (1)
- Glass (1)
- Glass Support (1)
- Goethe (1)
- Graphite furnace (1)
- Greek curse tablets (1)
- H/D-Austausch (1)
- H/D-Exchange (1)
- H2020 (1)
- HDF5 (1)
- HERFD-XAS (1)
- HR-CS-MAS (1)
- Hamonisierung (1)
- Handheld (1)
- Harmonisierung (1)
- Hazardous substances (1)
- Heart attack (1)
- Heavy metals (1)
- Hierarchical cluster analysis (1)
- High repetition-rate (1)
- High-Speed Separations (1)
- High-entropy alloy (1)
- High-resolution synchrotron XRF (1)
- Histology (1)
- Holistic science (1)
- Host–guest systems (1)
- Human Plasma (1)
- Hydrogen (1)
- ILC on detection methods (1)
- IgG determination (1)
- Image manipulation (1)
- Immuno assay (1)
- Immunometric assay (1)
- Immunometric biosensor (1)
- Immunosensor (1)
- Implant material (1)
- In situ EXAFS (1)
- In situ SAXS/WAXS (1)
- In situ studies (1)
- Inlet ionization (1)
- Instrument control (1)
- Instrumentation (1)
- Instrumentation utilization (1)
- Inter-laboratory comparison (1)
- Interner Standard (1)
- Ion mobility (1)
- Ionizing radiation (1)
- Iridium oxide (1)
- Klassifizierung (1)
- LA-ICP-MS (1)
- Laboratory automation (1)
- Laboratory management (1)
- Lacunary Keggin ion (1)
- Lead ions (1)
- Lead isotopes (1)
- Levitation (1)
- Li-ion battery (1)
- Luminol (1)
- MALDI (1)
- MALDI Imaging (1)
- MALDI Imaging MS (1)
- MALDI-TOF Massenspektrometrie (1)
- MALDI-ToF MS (1)
- MAS NMR spectroscopy (1)
- MCC (1)
- MDG ICP-ToF-MS (1)
- MOF (1)
- MOUSE (1)
- Machining (1)
- Macrocycles (1)
- Macrophagen (1)
- Magnetic nanocatalyst (1)
- Maia detector (1)
- Mass contents (1)
- Mass spectrometry (1)
- Massenspektrometrie (1)
- Material characterization (1)
- Matrices (1)
- Measurement data conversion (1)
- Mechanism (1)
- Mechanochemical synthesis (1)
- Metal nanoparticles (1)
- Metal-tag (1)
- Metformin (1)
- Methodenentwicklung Böden (1)
- Methodology (1)
- Metrics (1)
- Microdosimetry (1)
- Microdroplet generator (1)
- Microfluidic system (1)
- Microplastic analysis (1)
- Microplastic mass (1)
- Microplastic particles (1)
- Microplastic pathways (1)
- Microplastics analytic (1)
- Microplastics detection (1)
- Microplastics sampling (1)
- Microplastics standardisation (1)
- Mikroplastik Böden (1)
- Mikroplastik Massegehalt (1)
- Mikroplastik in Luft (1)
- Mikroplastikreferenzmaterial (1)
- Modelling (1)
- Molecular recognition (1)
- Molecule (1)
- Monitoring (1)
- Monoclonal Antibodies (1)
- Monoclonal antibodies (1)
- Monolith (1)
- Monolithic column (1)
- Motor controller (1)
- Multimodal (1)
- Multivariate Analyse (1)
- Multivariate Statistics (1)
- Multivariate analyses (1)
- Mycotoxin (1)
- Mycotoxins (1)
- NIR spectroscopy (1)
- NMR (1)
- NXsas (1)
- Nano (1)
- Nanocarrier (1)
- Nanocrystal (1)
- Nanomaterials (1)
- Nanoparticles (1)
- Nanoparticles with same nominal diameter (1)
- Nanoparticles with same nominal diameter; surface coating; two-dimensional off-line coupling (1)
- Nanoplastic (1)
- Nanoplastics (1)
- Natural language processing (1)
- NeXus (1)
- Near edge X-ray absorption fine structure spectroscopy (1)
- Nebra (1)
- Neural Network (1)
- Neural networks (1)
- Nondestructive testing techniques (1)
- OECD (1)
- Ochratoxin A (1)
- Online biosensor (1)
- Open Science (1)
- Optimierung (1)
- Outreach (1)
- P-aminothiophenol (1)
- PET (1)
- PXRD (1)
- Paper mills (1)
- Partial least square discriminant analysis (PLS-DA) (1)
- Particle size distribution (1)
- Pb isotopes (1)
- Peroxidase (1)
- Pharmacy (1)
- Phosphonate esters (1)
- Phosphonates (1)
- Photocatalysis (1)
- Photodegradation (1)
- Photooxidation (1)
- Plastic bottles (1)
- Pollen grains (1)
- Pollenkörner (1)
- Polycapillaries (1)
- Polyclonal Antibodies (1)
- Polyethyleneglycol (1)
- Polymer blends (1)
- Polymere Eigenschaften (1)
- Polymorph (1)
- Polymorphs (1)
- Polyoxometalates (1)
- Polyurethanes (1)
- Pomodore (1)
- Poster presentation (1)
- Principal component analysis (1)
- Principal component analysis (PCA) (1)
- Prisma (1)
- Probenpräparation (1)
- Procedure (1)
- Protein A (1)
- Protein Purification (1)
- Purification (1)
- Purity assessment (1)
- Python (1)
- Quality (1)
- Qualitätssicherung (1)
- Quantum dot (1)
- Quick-XAS (1)
- RUSEKU (1)
- RXES (1)
- Radiation (1)
- Radiation damage (1)
- Raman (1)
- Refractory alloys (1)
- Regeneration (1)
- Reifenabrieb (1)
- Release kinetics (1)
- Reliabiilty (1)
- Renewable Energy (1)
- Rhizopus (1)
- Ringversuch (1)
- Ringversuche (1)
- River (1)
- Robustness (1)
- Röntgenfluoreszenz (1)
- Salt (1)
- Sample preparation (1)
- Sata corrections (1)
- Scattering (1)
- Scientific misconduct (1)
- Sedimentation box (SB) (1)
- Sedimentationskasten (1)
- Sedimenttaionskasten (1)
- Self-assembly (1)
- Sensing (1)
- Separation (1)
- Sers (1)
- Si wafer filter (1)
- Silver nanoparticles (1)
- Sintered Material (1)
- Size (1)
- Size exclusion chromatography (1)
- Slags (1)
- Small-angle scattering (1)
- Soft-templated mesoporous films (1)
- Software (1)
- Solid support (1)
- Solvent-free (1)
- Sonochemical synthesis (1)
- Spinel (1)
- Sportböden (1)
- Supramolecular chemistry (1)
- Surface chemistry (1)
- Surface coating (1)
- Suspended particulate matter (SPM) (1)
- Sustainability and the Environment (1)
- TGA-FTIR (1)
- TGA-MS (1)
- TMB (1)
- TXRF-XAS (1)
- Tattoo inks (1)
- Temperature (1)
- Tesserae (1)
- Textile fibres (1)
- The MOUSE (1)
- Therapeutic Antibodies (1)
- Thermal analysis (1)
- Thermal degradation (1)
- Thermal extraction desorption-gas chromatography/mass spectrometry (TED-GC/MS), monitoring (1)
- Thermal extraction-desorption gas chromatography mass spectrometry (1)
- Thermo-desorption (1)
- Thermoanalyse (1)
- Thermoanalysis (1)
- Thermoanalytic (1)
- Thermoanalytical methods (1)
- Thermoanalytics (1)
- Thermoanalytik (1)
- Tire Wear (1)
- Tire particles (1)
- Tools to combat scientific misconduct (1)
- Toxic metals (1)
- Traceability (1)
- Transesterification (1)
- Two-dimensional off-line coupling (1)
- Ultrasound (1)
- Underwater LIBS (1)
- Urban (1)
- VAMAS (1)
- VRF (1)
- Vacuum ionization (1)
- Validation (1)
- Vanadium redox flow battery (1)
- WAXS (1)
- Wastewater (1)
- Water samples (1)
- Welding (1)
- X-Ray Fluorescence (1)
- X-ray absorption spectroscopy (1)
- X-ray and electron diffraction (1)
- X-ray fluorescence spectroscopy (1)
- X-ray photoelectron spectroscopy (1)
- X-ray scattering (1)
- X-ray spectroscopy (1)
- XAS (1)
- Xerogel (1)
- Zearalenone (1)
- Zinc analysis (1)
- Zirconium (1)
- electrocatalysis (1)
- microplastics, sampling, sampling techniques, water (1)
- nanostructured (1)
- µJ-DPSS laser (1)
- Ägyptisches Museum Berlin (1)
Organisationseinheit der BAM
- 6 Materialchemie (197) (entfernen)
Paper des Monats
- ja (1)
Besides conventional scanning X-ray fluorescence imaging at synchrotron sources, full-field X-ray fluorescence (FF-XRF) imaging techniques that do not implicitly require spatial scanning of the sample have become available. FF-XRF has become achievable thanks to the development of a new type of energy dispersive CCD-based 2D detector, also referred to as a 'color X-ray camera (CXC)' or 'SLcam'. We report on different imaging schemes for biological samples using FF-XRF imaging: (a) 2D 'zoom' imaging with pinhole optics using the 'camera obscura' principle; (b) 2D 'fixed magnification' imaging using magnifying polycapillary optics; and (c) 3D-FF-XRF imaging using an X-ray sheet beam or computed tomography (CT). The different FF-XRF imaging modes are illustrated using the crustacean Daphnia magna, a model organism for investigating the effects of metals on organism/ecosystem health, and foraminifera, a class of amoeboid protist. Detailed analytical characterization of the set-up is performed through analyzing various reference materials in order to determine limits of detection (LODs) and sensitivities. Experiments were performed using the BAMline at the BESSY synchrotron (Berlin, Germany) and using the P06 Hard X-ray Microprobe at the PETRAIII synchrotron (Hamburg, Germany).
Thermo-Desorption Gas Chromatography-Mass Spectrometry (TD-GC-MS) was used to investigate the thermal degradation of two different polyurethanes (PU). PU samples were heated at different heating rates and the desorbed products were collected in a cold injection system and thereafter submitted to GC-MS. Prospects and limitations of the detection and quantification of semi-volatile degradation products were investigated. A temperature dependent PU depolymerization was
found at temperatures above 200 °C proved by an increasing release of 1,4-butanediol and methylene diphenyl diisocyanate (MDI) representing the main building blocks of both polymers. Their release was monitored quantitatively based on external calibration with authentic compounds. Size Exclusion Chromatography (SEC) of the residues obtained after thermodesorption confirmed the initial competitive degradation mechanism indicating an equilibrium of crosslinking and depolymerization as previously suggested. Matrix-Assisted Laser Desorption Ionization (MALDI) mass spectrometry of SEC fractions of thermally degraded PUs provided additional hints on degradation mechanism.
Amyloid fibrils are polymers formed by proteins under specific conditions and in many cases they are related to pathogenesis, such as Parkinson’s and Alzheimer’s diseases. Their hallmark is the presence of a β-sheet structure. High resolution structural data on these systems as well as information gathered from multiple complementary analytical techniques is needed, from both a fundamental and a pharmaceutical perspective. Here, a previously reported de novo designed, pH-switchable coiled coil-based peptide that undergoes structural transitions resulting in fibril formation under physiological conditions has been exhaustively characterized by transmission electron microscopy (TEM), cryo-TEM, atomic force microscopy (AFM), wide-angle X-ray scattering (WAXS) and solid-state NMR (ssNMR). Overall, a unique 2-dimensional carpet-like assembly composed of large coexisiting ribbon-like, tubular and funnel-like structures with a clearly resolved protofilament substructure is observed. Whereas electron microscopy and scattering data point somewhat more to a hairpin model of β-fibrils, ssNMR data obtained from samples with selectively labelled peptides are in agreement with both, hairpin structures and linear arrangements.
This presentation highlights ongoing scientific misconduct as found in academic literature. This includes data- and image manipulation, and paper mills. Starting with an expose of examples, it delves deeper into the causes and metrics driving this phenomenon. Finally a range of possible tools is presented, that the young researcher can use to prevent themselves from sliding into the dark scientific methods.
The Color X-ray Camera CXC or SLcam® is an energy-resolving X-ray camera capable of energy- and space-resolved measurements. It consists of a high-speed CCD detector coupled to a polycapil-lary optic that conducts the X-ray photons from the probe to distinct pixels onto the detector. The camera is capable of fast acquisition of spatially and energy resolved fluorescence images. A dedicated software enables the acquisition and the online processing of the spectral data for all 69696 pixels, leading to a real-time visualization of the elements distribution in a sample. It was developed in a joint project with BAM, IFG Berlin and PN Sensors. In this contribution we will mainly discuss the use of the CXC at our beamline, the BAMline at BESSY II and imaging applications of the CXC from different areas, like biology and archaeometry. Additionally new developments for the use of the detector without optics, like wavelength dispersive detection or 1shot-XANES, will be presented.
The occurrence of small particles consisting of organic polymers, so-called microplastic (MP), in aquatic Environments attracts increasing interest in both public and science. Recent sampling campaigns in surface Waters revealed substantial numbers of particles in the size range from a few micrometers to a few millimeters. In order to validate sample preparation, identification and quantification and to investigate the behavior of MP particles and potential toxic effects on organisms, defined MP model particles are needed. Many studies use spherical compounds that probably behave differently compared to irregularly shaped MP found in environmental samples.
However, preparation and handling of MP particles are challenging tasks and have been systematically investigated in the present study. Polystyrene (PS) as a commonly found polymer with a density slightly above that of water was selected as polymer type for milling and fractionation studies. A cryogenic ball mill proved to be practical and effective to produce particles in the size range from 1 to 200 μm. The yield of small particles increased with increasing pre-cooling and milling durations. Depending on the concentration and the size, PS particles do not completely disperse in water and particles partly creep vertically up along glass walls. Stabilized MP suspensions without use of surfactants that might harm organisms are needed for toxicological studies. The stabilization of PS particle suspensions with ozone treatment reduced the wall effect and increased the number of dispersed PS particles but increased the dissolved organic carbon concentration and changed the size Distribution of the particles.
In der klinischen Diagnostik werden für zytometrische Messverfahren bereits eine Reihe von Reagenzien eingesetzt zur Markierung von Antikörper eingesetzt, um die Detektion von Biomarkern mittels Fluoreszenz- oder Flugzeitmassenspektrometrie zu ermöglichen.
Seit kurzem ist auch eine Imaging Mass Cytometry Kombination direkt erhältlich, wodurch der Nachweis von Biomarkern in Gewebeschnitten erreicht werden kann. Dazu wird eine Kopplung von Laser Ablation und induktiv gekoppeltem Plasma Massenspektrometrie eingesetzt, wobei ähnlich der Massenzytometrie, zuvor Antikörper mit Metallen markiert, und im Anschluss mit dem Gewebeschnitt inkubiert werden. Durch die hohe Ortsauflösung können die Biomarker lokalisiert, und zukünftig vielleicht auch quantifiziert werden.
Insbesondere Lanthanide eignen sich als Markierungsmetalle, da sie einen niedrigen Untergrund und chemisch ähnliches Verhalten zueinander aufweisen. Allein durch diese Elemente können bereits etwa 15 Parameter unterschieden werden, was durch isotopenreine Standards weiter gesteigert werden kann.
Vom Markierungsgrad abhängig werden unterschiedlich viele Metalle am Antikörper gebunden, und beeinflussen so die Sichtbarkeit im ICP-MS. Nanopartikel könnten daher eine deutliche Steigerung der Sensitivität bewirken. GdVO4 Nanokristalle scheinen bisher sehr vielversprechend und bieten neben multiparametrischen Anwendungen auch Multimodalität.
Die Synthese der Nanokristalle zeigte hohe Homogenität und Reproduzierbarkeit in Partikelgröße in der Zusammensetzung. Ein erstes Experiment mit einer Zellkultur konnte bereits die effiziente Markierung der Zellen unter Beweis stellen, wobei durch hohe Signalstärke auch subzelluläre Auflösung in der LA-ICP-MS erreicht werden konnte.
Two divalent manganese aminophosphonates, manganese mono (nitrilotrimethylphosphonate) (MnNP3) and manganese bis N-(carboxymethyl)iminodi(methylphosphonate)) (Mn(NP2AH)2), have been prepared by mechanochemical synthesis and characterized by powder X-ray diffraction (PXRD). The structure of the novel compound Mn(NP2AH)2 was determined from PXRD data. MnNP3 as well as Mn(NP2AH)2 exhibits a chain-like structure.
In both cases, the manganese atom is coordinated by six oxygen atoms in a distorted octahedron. The local coordination around Mn was further characterized by extended X-ray absorption fine structure. The synthesis process was followed in situ by synchrotron X-ray diffraction revealing a three-step reaction mechanism. The asprepared manganese(II) phosphonates were calcined on air.
All samples were successfully tested for their suitability as catalyst material in the oxygen evolution reaction.