4.1 Biologische Materialschädigung und Referenzorganismen
Filtern
Dokumenttyp
- Zeitschriftenartikel (84) (entfernen)
Sprache
- Englisch (84) (entfernen)
Schlagworte
- Antimicrobial resistance (6)
- Bacteria (6)
- Biocides (6)
- Ectoine (5)
- Biofilm (4)
- Biofilms (4)
- Polyethylene (4)
- Wood protection (4)
- Disinfection (3)
- NAP-XPS (3)
- Osmoadaptation (3)
- Termites (3)
- Wood Protection (3)
- Antimicrobial (2)
- Bacterial adhesion (2)
- Biocorrosion (2)
- Brown-rot fungi (2)
- Condensed Matter Physics (2)
- DNA (2)
- Degradation (2)
- Energy Engineering and Power Technology (2)
- Evolution (2)
- Fuel Technology (2)
- Halomonas elongata (2)
- Horizontal gene transfer (2)
- Insect biotechnology (2)
- Isoptera (2)
- Keratin (2)
- Laser processing (2)
- Laser-induced periodic surface structures (LIPSS) (2)
- Leaching (2)
- MIC (2)
- Method development (2)
- Microbiologically influenced corrosion (2)
- NanoSIMS (2)
- Nanoparticles (2)
- Nosema ceranae (2)
- Osmia bicornis (2)
- Pseudomonas aeruginosa (2)
- Renewable Energy, Sustainability and the Environment (2)
- Tineola bisselliella (2)
- Wild bees (2)
- XPS (2)
- 2D nanomaterials (1)
- 3D printing (1)
- A-DNA conformation (1)
- Acidobacteria (1)
- Alkylating agents (1)
- Amphiphilic polymer (1)
- Anaerobic pathways (1)
- Anobium punctatum (1)
- Antagonism (1)
- Antibacterial (1)
- Antibacterial polymer (1)
- Antibacterial surfaces (1)
- Antibiotic resistance (1)
- Antibiotics (1)
- Antifouling (1)
- Antimicrobial coating (1)
- Antimicrobial test (1)
- Antimicrobials (1)
- Antiseptic agents (1)
- Artificial weathering (1)
- Aspergillus (1)
- Atomic and Molecular Physics and Optics (1)
- Automated analysis (1)
- BODIPY (1)
- Bacillus subtilis (1)
- Bacterial attachment (1)
- Bacterial cell cycle (1)
- Bacterial second messenger (1)
- Basidiomycetes (1)
- Bee diseases (1)
- Bee health (1)
- Beneficial microbes (1)
- Biocide tolerance (1)
- Biodeterioration (1)
- Biodeterioration and biodegradation (1)
- Biofilm formation (1)
- Biofilm quantification (1)
- Bioinformatics (1)
- Bioinformatics virology viruses software (1)
- Biokorrosion (1)
- Biological pest control (1)
- Biomimetic (1)
- Biosynthesis (1)
- Biphasic growth (1)
- C-di-GMP (1)
- COST action CA15114 AMICI (1)
- Calcareous deposits (1)
- Carbon steel (1)
- Carbon steel corrosion (1)
- Cathodic protection (1)
- Cell appendages (1)
- Cell studies (1)
- Cell-envelope (1)
- Cellulose synthase (1)
- Chemicals (1)
- Cleridae (1)
- Coleoptera (1)
- Compatible solute (1)
- Coniophora puteana (1)
- Conjugate (1)
- Conjugation (1)
- Coptotermes (1)
- Core microbiome (1)
- Cross-feeding (1)
- Cross-resistance (1)
- Cryo XPS (1)
- CuNPs (1)
- Cultural heritage (1)
- Cupriavidus campinensis (1)
- DSM 5009 (1)
- Decomposition point (1)
- Degradable polymer (1)
- Denitrification (1)
- Desert ecology (1)
- Dielectric heating (1)
- Dietary adaptation (1)
- Diffractive gratings (1)
- Direct laser writing (1)
- Disinfection Fuel (1)
- Disposal (1)
- Diversity (1)
- Drywood termite (1)
- Dye (1)
- E. coli (1)
- Efficacy (1)
- Electronic (1)
- Environment (1)
- Environmental conditions (1)
- Environmental simulations (1)
- Exocrine gland (1)
- External (1)
- Extremophile (1)
- F pili (1)
- Fenton-like reaction (1)
- Flow system (1)
- Fluorescence spectroscopy (1)
- Fluoride (1)
- Fluoride nanoparticles (1)
- Fluorides (1)
- Fluorolytic sol-gel synthesis (1)
- Fluorolytic sol−gel (1)
- Food fermentation (1)
- Fuel sorption (1)
- Functionalized graphene (1)
- Fungal decay (1)
- Fungicidal property (1)
- Fungiculture (1)
- Fusarium (1)
- Gene expression (1)
- Genome sequence (1)
- Geology (1)
- Graphene (1)
- Graphene–bacteria interaction (1)
- Growth-rate homeostasis (1)
- Gut symbionts (1)
- Halogenation (1)
- Halophilic bacteria (1)
- Healthcare (1)
- High density polyethylene (1)
- Holzschutzmittel (1)
- Hospital premises (1)
- Hydrogen permeation (1)
- Hydrogen storage (1)
- Hydrogenasen (1)
- Hydrophobic interaction (1)
- Hylotrupes bajulus, Anobium punctatum, natural durability, tropical wood, native wood. (1)
- Hyperarid (1)
- Hypopharynx (1)
- IR spectroscopy (1)
- Immunity (1)
- Infections (1)
- Insect evolution (1)
- Insecticide (1)
- Interdisciplinarity (1)
- Ionic liquid (1)
- Ir DNA staining approach (1)
- Issues (1)
- Korynetes caeruleus (1)
- Laboratory breeding (1)
- Labrum (1)
- Laser-induced nanostructures (1)
- Laser-modified surface (1)
- Life history data (1)
- Lifetime (1)
- Low alloy steel (1)
- Marek's virus (1)
- Mechanosensitive channel (1)
- Melting point (1)
- Melting temperature (1)
- Metabolic engineering (1)
- Metabolic flux analysis (1)
- Metabolic modeling (1)
- Metabolism (1)
- Metabolomics (1)
- Methane (1)
- Methanogen (1)
- Microbial adhesions (1)
- Microbial simulation, (1)
- Microbially Induced Corrosion (1)
- Microbiological influenced corrosion MIC (1)
- Micromonospora aurantiaca (1)
- Micropatterning (1)
- Microwaves (1)
- Model (1)
- Modeling (1)
- Modelling studies (1)
- Modified mycotoxins (1)
- Moisture (1)
- Moisture performance (1)
- Molecular clock (1)
- MscS (1)
- Mud volcanoe fluids (1)
- Multi-resistant bacteria (1)
- Multiple lines of evidence (1)
- Multiport (1)
- Mussel-inspired coating (1)
- Mussel-inspired materials (1)
- Mutation rate (1)
- Mycotoxin (1)
- Nano Particles (1)
- Natural durability (1)
- Natural products discovery (1)
- Near ambient x-ray photoelectron spectroscopy (1)
- Next generation sequencing (1)
- Nitrous oxide (1)
- Nonvolatile (1)
- One-step ionic liquids synthesis (1)
- Optical and Magnetic Materials (1)
- Osmotic shock (1)
- Osteogenesis (1)
- P. Fluorescens (1)
- Paper sizings (1)
- Particle synthesis (1)
- Pathogen spillover (1)
- Pathogen transmission (1)
- Performance (1)
- Permeability (1)
- Persian historical recipes (1)
- Persistence (1)
- Pest control (1)
- Phenotypic heterogeneity (1)
- Phenotypic variation (1)
- Photodynamic therapy (1)
- Photonics (1)
- Physical and optical characteristics (1)
- Plastic degradation (1)
- Polydopamine (1)
- Polyethylene terephthalate (1)
- Polyglycerol (1)
- Polyioinic liquid (1)
- Polymer-based products (1)
- Proteome (1)
- Pseudomonas fluorescens (1)
- Pseudomonas veronii (1)
- Ptinidae (1)
- Quasispecies (1)
- RNA-Sequencing (1)
- Radio waves (1)
- Reactive oxygen species (1)
- Reactor conditions (1)
- Resistance model (1)
- Rhizopus (1)
- Rhizopus and Aspergillus oryzae (1)
- Rhodonia placenta (1)
- Ruthenium (1)
- SEM (1)
- SEM micrography (1)
- SEM wood characterization (1)
- SIMS (1)
- Sc-ICP-ToF-MS (1)
- Self-assembled monolayer (1)
- Sensors (1)
- Silica and polystyrene nanoparticles (1)
- Silver (1)
- Single cell (1)
- Single cell microbiology (1)
- Social (1)
- Social insects (1)
- Software (1)
- Soil contact (1)
- Soldier (1)
- Solitary bees (1)
- Solute excretion (1)
- Spectral imaging (1)
- Standardisation (1)
- Suppression (1)
- Survival rates (1)
- Symbiosis (1)
- Synergy (1)
- Synthetic metabolism (1)
- Termite-associated microbes (1)
- Termitoidae (1)
- Thermodynamic (1)
- Thioimidazolium (1)
- Touch surfaces (1)
- Transcriptomics (1)
- UV-irradiation (1)
- Ultrastructure (1)
- Virology (1)
- Virulence (1)
- Viruses (1)
- Water (1)
- Water atmosphere (1)
- Water stable isotope analysis (1)
- Water uptake (1)
- White-rot fungi (1)
- Wood Modification (1)
- X-ray tomographic (1)
- Zearalenone (1)
- Zearalenone sulfate (1)
- a-zearalenol (1)
- dsDAN monolayer (1)
- iChip (1)
- pH probe (1)
- underexplored phyla (1)
Organisationseinheit der BAM
- 4 Material und Umwelt (84)
- 4.1 Biologische Materialschädigung und Referenzorganismen (84)
- 6 Materialchemie (17)
- 4.0 Abteilungsleitung und andere (8)
- 1 Analytische Chemie; Referenzmaterialien (7)
- 6.1 Oberflächen- und Dünnschichtanalyse (6)
- 6.2 Material- und Oberflächentechnologien (6)
- 5 Werkstofftechnik (3)
- 6.3 Strukturanalytik (3)
- 8 Zerstörungsfreie Prüfung (3)
- 1.2 Biophotonik (2)
- 1.7 Organische Spuren- und Lebensmittelanalytik (2)
- 1.8 Umweltanalytik (2)
- 4.3 Schadstofftransfer und Umwelttechnologien (2)
- 8.1 Sensorik, mess- und prüftechnische Verfahren (2)
- 1.1 Anorganische Spurenanalytik (1)
- 1.4 Prozessanalytik (1)
- 3 Gefahrgutumschließungen; Energiespeicher (1)
- 3.1 Sicherheit von Gefahrgutverpackungen und Batterien (1)
- 5.1 Mikrostruktur Design und Degradation (1)
- 5.3 Polymere Verbundwerkstoffe (1)
- 5.4 Multimateriale Fertigungsprozesse (1)
- 6.6 Physik und chemische Analytik der Polymere (1)
- 6.7 Materialsynthese und Design (1)
- 7 Bauwerkssicherheit (1)
- 7.5 Technische Eigenschaften von Polymerwerkstoffen (1)
- 8.0 Abteilungsleitung und andere (1)
- 9 Komponentensicherheit (1)
- 9.0 Abteilungsleitung und andere (1)
Paper des Monats
- ja (6)
Despite the recognized excellence of virology and bioinformatics, these two communities have interacted surprisingly sporadically, aside from some pioneering work on HIV-1 and influenza. Bringing together the Expertise of bioinformaticians and virologists is crucial, since very specific but fundamental computational approaches are required for virus research, particularly in an era of big data. Collaboration between virologists and bioinformaticians is necessary to improve existing analytical tools, cloud-based systems, computational resources, data sharing approaches, new diagnostic tools, and bioinformatic training. Here, we highlight current progress and discuss potential avenues for future developments in this promising era of virus bioinformatics. We end by presenting an overview of current technologies, and by outlining some of the Major challenges and Advantages that bioinformatics will bring to the field of virology.
Quaternary ammonium compounds (QACs) are widely used as active agents in disinfectants, antiseptics, and preservatives. Despite being in use since the 1940s, there remain multiple open questions regarding their detailed mode-of-action and the mechanisms, including phenotypic heterogeneity, that can make bacteria less susceptible to QACs. To facilitate studies on resistance mechanisms towards QACs, we synthesized a fluorescent quaternary ammonium compound, namely N-dodecyl-N,N-dimethyl-[2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]ethyl]azanium-iodide (NBD-DDA). NBD-DDA is readily detected by flow cytometry and fluorescence microscopy with standard GFP/FITC-settings, making it suitable for molecular and single-cell studies. As a proof-of-concept, NBD-DDA was then used to investigate resistance mechanisms which can be heterogeneous among individual bacterial cells. Our results reveal that the antimicrobial activity of NBD-DDA against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa is comparable to that of benzalkonium chloride (BAC), a widely used QAC, and benzyl-dimethyl-dodecylammonium chloride (BAC12), a mono-constituent BAC with alkyl-chain length of 12 and high structural similarity to NBD-DDA. Characteristic time-kill kinetics and increased tolerance of a BAC tolerant E. coli strain against NBD-DDA suggest that the mode of action of NBD-DDA is similar to that of BAC. As revealed by confocal laser scanning microscopy (CLSM), NBD-DDA is preferentially localized to the cell envelope of E. coli, which is a primary target of BAC and other QACs. Leveraging these findings and NBD-DDA‘s fluorescent properties, we show that reduced cellular accumulation is responsible for the evolved BAC tolerance in the BAC tolerant E. coli strain and that NBD-DDA is subject to efflux mediated by TolC. Overall, NBD-DDA’s antimicrobial activity, its fluorescent properties, and its ease of detection render it a powerful tool to study resistance mechanisms of QACs in bacteria and highlight its potential to gain detailed insights into its mode-of-action.
Terrestrial mud volcanoes are unique structures driven by tectonic pressure and fluids from the deep subsurface. These structures are mainly found in active tectonic zones, such as the area near the Los Bajos Fault in Trinidad. Here we report a chemical and microbiological characterization of three mud volcanoes, which included analyses of multiple liquid and solid samples from the mud volcanoes. Our study confirms previous suggestions that at least some of the mud volcano fluids are a mixture of deeper salt-rich water and surficial/precipitation water. No apparent water quality differences were found between sampling sites north and south of a major geological fault line. Microbiological analyses revealed diverse communities, both aerobic and anaerobic, including sulfate reducers, methanogens, carbon dioxide fixing and denitrifying bacteria. Several identified species were halophilic and likely derived from the deeper salt-rich subsurface water, while we also cultivated pathogenic species from the Vibrionaceae, Enterobacteriaceae, Shewanellaceae, and Clostridiaceae. These microorganisms were likely introduced into the mud volcano fluids both from surface water or shallow ground-water, and perhaps to a more minor degree by rain water. The identified pathogens are a major health concern that needs to be addressed.
AbstractThis work addresses the critical need for multifunctional materials and substrate‐independent high‐precision surface modification techniques that are essential for advancing microdevices and sensing elements. To overcome existing limitations, the versatility of mussel‐inspired materials (MIMs) is combined with state‐of‐the‐art multiphoton direct laser writing (DLW) microfabrication. In this way, 2D and 3D MIM microstructures of complex designs are demonstrated with sub‐micron to micron resolution and extensive post‐functionalization capabilities. This study includes polydopamine (PDA), mussel‐inspired linear, and dendritic polyglycerols (MI‐lPG and MI‐dPG), allowing their direct microstructure on the substrate of choice with the option to tailor the patterned topography and morphology in a controllable manner. The functionality potential of MIMs is demonstrated by successfully immobilizing and detecting single‐stranded DNA on MIM micropattern and nanoarray surfaces. In addition, easy modification of MIM microstructure with silver nanoparticles without the need of any reducing agent is shown. The methodology developed here enables the integration of MIMs in advanced applications where precise surface functionalization is essential.