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Experimentshow that the strength of Ni-base superalloystrongly depends on the actual morphology of the microstructure. This makes a multiphase micro-mechanical modelling indispensable for a reliable safety analysis. Unfortunately, the classical crystal plasticity theory leads to erroneous predictions, when applied to the scale of the microstructure. This paper suggests that this failure is related to a breakdown of the meaning of plastic strain at the scale of the size of dislocation loops. We propose a global modelling of the compound that overcomes the deficiencies of local crystal plasticity at this description level.