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- 2007 (4) (entfernen)
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- Englisch (4)
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- Bone (2)
- NMR (2)
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Eingeladener Vortrag
- nein (1)
The results of copolymer characterization by coupling of chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) techniques and subsequent calculation of copolymer composition using a novel software tool MassChrom2D are presented. For high-resolution mass analysis copolymer samples were fractionated by means of liquid adsorption chromatography (LAC). These fractions were investigated off-line by MALDI-TOF MS. Various mono-n-butyl ethers of polyethylene oxide-polypropylene oxide copolymers (PEO-co-PPO) were investigated. As well as the copolymer composition presented in two-dimensional plots, the applied approach can give additional hints on specific structure-dependent separation conditions in chromatography.
A solid-state NMR comparison of the mineral structure in bone from diseases joints in the horse
(2007)
In this work, subchondral cortical bone material is investigated from the joints of five horses, three of which presented with no clinical signs or radiographic signs of osteoarthritis and two of which suffered osteoarthritis joint disease, as judged by clinical and radiographic assessment and histological findings. The horse is a good model for osteoarthritis in humans, so the aim of this study is to use nuclear magnetic resonance (NMR) for a detailed investigation of the bone structure in bone material affected by osteoarthritis. In particular, we report on the assessment of the mineral structure of these samples as viewed by solid-state NMR.