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The presentation deals with the progess, the use of beads brings with it when developing and using immunoanalytical methods. While with conventional assays (e.g. ELISA) fill/empty/wash steps have to be performed within the same microplate well, antibodies on beads bring the possibility of incubating the sample with the capture antibodies in one compartment and then transport it, e.g. in microfluidic channels, to the site of detection. Especially magnetic nanoparticles, that can be captured and released easily, have a wide field of application.
A vast number of emerging pollutants is being detected in the environment. Another lingering problem are health-threatening contaminants, such as mycotoxins, that deteriorate food and feed, and the pathogens themselves. Analytical methods, suitable for trace analysis, are needed that are desirably also fast, inexpensive and, if possible, robust and portable. It is set out, how immunoana-lytical, i.e., antibody-based methods, which are elaborated in a broad range of formats, can be profitably used to gain insights on the distribution and concentration trends of the target analytes at the point-of-need.