Luminescent, Semiconductor Nanoparticle-Loadedpolymer Microbeads–Comparingparticlearchitectures
- Luminescent polymer microparticles (PMPs) are applied in various (bio)analytical and diagnostic processes.[1] The staining of these beads is important for the realization of optically distinguishable barcodes that can be read out, e.g., by a flow cytometer or fluorescence microscope. Typically, luminescent semiconductor nanoparticles (NPs) absorb in a broad wavelength range and show narrow emission bands, which enables simultaneous excitation of differently colored luminophores and facilitates a spectral discrimination.[1] This makes them ideal candidates for this purpose and encouraged us to explore and develop a simple, effective approach to luminescent semiconductor NP encoding of polystyrene PMPs and identify suitable synthesis conditions.[2]
Until now, mainly semiconductor quantum dots (QDs) have been used for the synthesis of luminescent PMPs, although NPs with different shapes could introduce beneficial new features. Aiming for the application of our developed procedure toLuminescent polymer microparticles (PMPs) are applied in various (bio)analytical and diagnostic processes.[1] The staining of these beads is important for the realization of optically distinguishable barcodes that can be read out, e.g., by a flow cytometer or fluorescence microscope. Typically, luminescent semiconductor nanoparticles (NPs) absorb in a broad wavelength range and show narrow emission bands, which enables simultaneous excitation of differently colored luminophores and facilitates a spectral discrimination.[1] This makes them ideal candidates for this purpose and encouraged us to explore and develop a simple, effective approach to luminescent semiconductor NP encoding of polystyrene PMPs and identify suitable synthesis conditions.[2]
Until now, mainly semiconductor quantum dots (QDs) have been used for the synthesis of luminescent PMPs, although NPs with different shapes could introduce beneficial new features. Aiming for the application of our developed procedure to non-spherical NPs, we systematically investigated the luminescence properties of the resulting NP-stained beads using fluorescence and integrating sphere spectroscopy as well as fluorescence and electron microscopy. These studies showed that the suitability of semiconductor NPs for the synthesis of luminescent PMPs depends not only on their shape, but also heavily on their surface chemistry.[3] The successful incorporation of nonspherical NPs opens the path to include even more NPs, and the results can help to deduce future applications for the beads which best suit their specific properties.…


| Autor*innen: | Lena Scholtz |
|---|---|
| Koautor*innen: | J. G. Eckert, F. Lübkemann-Warwas, R. T. Graf, A. Kunst, O. Hübner, Karl David WegnerORCiD, N. C. Bigall, Ute Resch-GengerORCiD |
| Dokumenttyp: | Vortrag |
| Veröffentlichungsform: | Präsentation |
| Sprache: | Englisch |
| Jahr der Erstveröffentlichung: | 2025 |
| Organisationseinheit der BAM: | 1 Analytische Chemie; Referenzmaterialien |
| 1 Analytische Chemie; Referenzmaterialien / 1.2 Biophotonik | |
| DDC-Klassifikation: | Naturwissenschaften und Mathematik / Chemie / Analytische Chemie |
| Technik, Medizin, angewandte Wissenschaften / Ingenieurwissenschaften / Ingenieurwissenschaften und zugeordnete Tätigkeiten | |
| Freie Schlagwörter: | Barcode; Characterization; Encoding; Fluorescence; Lifetime; Mechanism; Method; Nano; Particle; Platelet; Polymer particle; Polymerization; Quality assurance; Quantum dot; Quantum rod; Quantum yield; Surface chemistry; Synthesis |
| Themenfelder/Aktivitätsfelder der BAM: | Chemie und Prozesstechnik |
| Chemie und Prozesstechnik / Chemische Charakterisierung und Spurenanalytik | |
| Material | |
| Material / Advanced Materials | |
| Umwelt | |
| Veranstaltung: | E-MRS Fall Meeting 2025 |
| Veranstaltungsort: | Warsaw, Poland |
| Beginndatum der Veranstaltung: | 15.09.2025 |
| Verfügbarkeit des Dokuments: | Datei im Netzwerk der BAM verfügbar ("Closed Access") |
| Datum der Freischaltung: | 01.10.2025 |
| Referierte Publikation: | Nein |
| Eingeladener Vortrag (wissenschaftliche Konferenzen): | Nein |

